| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Veronika Pak, Quadri Adewale, Danilo Bzdok, Mahsa Dadar, Yashar Zeighami, Yasser Iturria-Medin. Distinctive whole-brain cell types predict tissue damage patterns in thirteen neurodegenerative conditions. eLife. vol 12. 2024-03-21. PMID:38512130. |
by unifying spatial gene expression, structural mri, and cell deconvolution, here we describe how the human brain distribution of canonical cell types extensively predicts tissue damage in 13 neurodegenerative conditions, including early- and late-onset alzheimer's disease, parkinson's disease, dementia with lewy bodies, amyotrophic lateral sclerosis, mutations in presenilin-1, and 3 clinical variants of frontotemporal lobar degeneration (behavioral variant, semantic and non-fluent primary progressive aphasia) along with associated three-repeat and four-repeat tauopathies and tdp43 proteinopathies types a and c. we reconstructed comprehensive whole-brain reference maps of cellular abundance for six major cell types and identified characteristic axes of spatial overlapping with atrophy. |
2024-03-21 |
2024-03-23 |
human |
| Dror Shir, Nick Corriveau-Lecavalier, Camilo Bermudez Noguera, Leland Barnard, Nha Trang Thu Pham, Hugo Botha, Joseph R Duffy, Heather M Clark, Rene L Utianski, David S Knopman, Ronald C Petersen, Bradley F Boeve, Melissa E Murray, Aivi T Nguyen, R Ross Reichard, Dennis W Dickson, Gregory S Day, Walter K Kremers, Neill R Graff-Radford, David T Jones, Mary M Machulda, Julie A Fields, Jennifer L Whitwell, Keith A Josephs, Jonathan Graff-Radfor. Clinicoradiological and neuropathological evaluation of primary progressive aphasia. Journal of neurology, neurosurgery, and psychiatry. 2024-03-21. PMID:38514176. |
three ppa variants correlate with distinct underlying pathologies: semantic variant ppa (svppa) with transactive response dna-binding protein of 43 kd (tdp-43) proteinopathy, agrammatic variant ppa (agppa) with tau deposition and logopenic variant ppa (lvppa) with alzheimer's disease (ad). |
2024-03-21 |
2024-03-24 |
Not clear |
| Mengjie Huang, Ramon Landin-Romero, Sophie Matis, Marshall A Dalton, Olivier Pigue. Longitudinal volumetric changes in amygdala subregions in frontotemporal dementia. Journal of neurology. 2024-01-24. PMID:38265470. |
patients clinically diagnosed with behavioral variant ftd (bvftd) (n = 20), semantic dementia (sd) (n = 20), primary nonfluent aphasia (pnfa) (n = 20), alzheimer's disease (ad) (n = 20), and 20 matched healthy controls underwent whole brain structural mri. |
2024-01-24 |
2024-01-26 |
Not clear |
| Fang Lan, Daniel Roquet, Marshall A Dalton, Hashim El-Omar, Rebekah M Ahmed, Olivier Piguet, Muireann Iris. Exploring graded profiles of hippocampal atrophy along the anterior-posterior axis in semantic dementia and Alzheimer's disease. Neurobiology of aging. vol 135. 2024-01-17. PMID:38232501. |
exploring graded profiles of hippocampal atrophy along the anterior-posterior axis in semantic dementia and alzheimer's disease. |
2024-01-17 |
2024-01-20 |
human |
| Nicole D Cilia, Claudio De Stefano, Francesco Fontanella, Sabato Marco Siniscalch. How word semantics and phonology affect handwriting of Alzheimer's patients: A machine learning based analysis. Computers in biology and medicine. vol 169. 2024-01-05. PMID:38181607. |
how word semantics and phonology affect handwriting of alzheimer's patients: a machine learning based analysis. |
2024-01-05 |
2024-01-08 |
cat |
| Nicole D Cilia, Claudio De Stefano, Francesco Fontanella, Sabato Marco Siniscalch. How word semantics and phonology affect handwriting of Alzheimer's patients: A machine learning based analysis. Computers in biology and medicine. vol 169. 2024-01-05. PMID:38181607. |
in this paper, we investigated how word semantics and phonology affect the handwriting of people affected by alzheimer's disease. |
2024-01-05 |
2024-01-08 |
cat |
| Min Jeong Kwon, Subin Lee, Jieun Park, Sungman Jo, Ji Won Han, Dae Jong Oh, Jun-Young Lee, Joon Hyuk Park, Jae Hyoung Kim, Ki Woong Ki. Textural and Volumetric Changes of the Temporal Lobes in Semantic Variant Primary Progressive Aphasia and Alzheimer's Disease. Journal of Korean medical science. vol 38. issue 41. 2023-10-24. PMID:37873627. |
textural and volumetric changes of the temporal lobes in semantic variant primary progressive aphasia and alzheimer's disease. |
2023-10-24 |
2023-11-08 |
Not clear |
| Min Jeong Kwon, Subin Lee, Jieun Park, Sungman Jo, Ji Won Han, Dae Jong Oh, Jun-Young Lee, Joon Hyuk Park, Jae Hyoung Kim, Ki Woong Ki. Textural and Volumetric Changes of the Temporal Lobes in Semantic Variant Primary Progressive Aphasia and Alzheimer's Disease. Journal of Korean medical science. vol 38. issue 41. 2023-10-24. PMID:37873627. |
we aimed to investigate the patterns of neurodegeneration in semantic variant primary progressive aphasia (svppa) and alzheimer's disease (ad) by comparing the temporal gray matter texture and volume between cognitively normal controls and older adults with svppa and ad. |
2023-10-24 |
2023-11-08 |
Not clear |
| Anna Marier, Mahsa Dadar, Florence Bouhali, Maxime Montembeaul. Irregular word reading as a marker of cognitive and semantic decline in Alzheimer's disease rather than an estimate of premorbid intellectual abilities. Research square. 2023-10-16. PMID:37841870. |
irregular word reading as a marker of cognitive and semantic decline in alzheimer's disease rather than an estimate of premorbid intellectual abilities. |
2023-10-16 |
2023-11-08 |
human |
| Ming-Ching Lin, Yu-Chun Chi. Application of the Semantic Fluency Test in the Screening of Mandarin-Chinese-Speaking Older Adults with Mild Dementia of the Alzheimer Type. Behavioral sciences (Basel, Switzerland). vol 13. issue 8. 2023-08-25. PMID:37622775. |
furthermore, this study proposed optimal cutoff points and calculated the auc for various test durations (i.e., 30 s, 45 s and 60 s) and semantic categories in the semantic fluency test, which may serve as a reference that would help clinical personnel distinguish between older adults without cognitive impairments and those with dementia of alzheimer type in taiwan. |
2023-08-25 |
2023-09-07 |
human |
| Sandra Invernizzi, Alice Bodart, Laurent Lefebvre, Isabelle Simoes Loureir. Correction: The role of semantic assessment in the differential diagnosis between late‑life depression and Alzheimer's disease or amnestic mild cognitive impairment: systematic review and meta‑analysis. European journal of ageing. vol 20. issue 1. 2023-08-23. PMID:37612530. |
correction: the role of semantic assessment in the differential diagnosis between late‑life depression and alzheimer's disease or amnestic mild cognitive impairment: systematic review and meta‑analysis. |
2023-08-23 |
2023-09-07 |
Not clear |
| Invernizzi Sandra, Bodart Alice, Lefebvre Laurent, Simoes Loureiro Isabell. The role of semantic assessment in the differential diagnosis between late-life depression and Alzheimer's disease or amnestic mild cognitive impairment: systematic review and meta-analysis. European journal of ageing. vol 20. issue 1. 2023-08-10. PMID:37563432. |
the role of semantic assessment in the differential diagnosis between late-life depression and alzheimer's disease or amnestic mild cognitive impairment: systematic review and meta-analysis. |
2023-08-10 |
2023-08-16 |
Not clear |
| Chris J D Hardy, Cathleen Taylor-Rubin, Beatrice Taylor, Emma Harding, Aida Suarez Gonzalez, Jessica Jiang, Laura Thompson, Rachel Kingma, Anthipa Chokesuwattanaskul, Ffion Walker, Suzie Barker, Emilie Brotherhood, Claire Waddington, Olivia Wood, Nikki Zimmermann, Nuriye Kupeli, Keir X X Yong, Paul M Camic, Joshua Stott, Charles R Marshall, Neil P Oxtoby, Jonathan D Rohrer, Anna Volkmer, Sebastian J Crutch, Jason D Warre. Symptom-led staging for semantic and non-fluent/agrammatic variants of primary progressive aphasia. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-08-07. PMID:37548125. |
here we set out to create a symptom-led staging system for the canonical semantic and non-fluent/agrammatic variants of primary progressive aphasia (ppa), which present unique diagnostic and management challenges not well captured by functional scales developed for alzheimer's disease and other dementias. |
2023-08-07 |
2023-08-14 |
Not clear |
| Rocio Olmos-Villaseñor, Consuelo Sepulveda-Silva, Teresa Julio-Ramos, Eduardo Fuentes-Lopez, David Toloza-Ramirez, Rodrigo A Santibañez, David A Copland, Carolina Mendez-Orellan. Phonological and Semantic Fluency in Alzheimer's Disease: A Systematic Review and Meta-Analysis. Journal of Alzheimer's disease : JAD. 2023-07-24. PMID:37482994. |
semantic and phonological fluency (sf and pf) are routinely evaluated in patients with alzheimer's disease (ad). |
2023-07-24 |
2023-08-14 |
Not clear |
| Erin Burke, John Gunstad, Phillip Hamric. Comparing global and local semantic coherence of spontaneous speech in persons with Alzheimer's disease and healthy controls. Applied Corpus Linguistics. vol 3. issue 3. 2023-07-21. PMID:37476646. |
comparing global and local semantic coherence of spontaneous speech in persons with alzheimer's disease and healthy controls. |
2023-07-21 |
2023-08-14 |
Not clear |
| Jet M J Vonk, Mirjam I Geerlings, Justina F Avila-Rieger, Carolyn L Qian, Nicole Schupf, Richard Mayeux, Adam M Brickman, Jennifer J Manl. Semantic item-level metrics relate to future memory decline beyond existing cognitive tests in older adults without dementia. Psychology and aging. 2023-05-18. PMID:37199965. |
in alzheimer's disease dementia, both semantic and episodic memory become impaired early in the disease process. |
2023-05-18 |
2023-08-14 |
human |
| Jessica Jiang, Jeremy C S Johnson, Maï-Carmen Requena-Komuro, Elia Benhamou, Harri Sivasathiaseelan, Anthipa Chokesuwattanaskul, Annabel Nelson, Ross Nortley, Rimona S Weil, Anna Volkmer, Charles R Marshall, Doris-Eva Bamiou, Jason D Warren, Chris J D Hard. Comprehension of acoustically degraded speech in Alzheimer's disease and primary progressive aphasia. Brain : a journal of neurology. 2023-05-15. PMID:37184986. |
here we addressed this issue in a cohort of 19 patients with typical alzheimer's disease and 30 patients representing the three canonical syndromes of primary progressive aphasia (nonfluent/agrammatic variant primary progressive aphasia; semantic variant primary progressive aphasia; logopenic variant primary progressive aphasia), compared to 25 healthy age-matched controls. |
2023-05-15 |
2023-08-14 |
human |
| Jessica Jiang, Jeremy C S Johnson, Maï-Carmen Requena-Komuro, Elia Benhamou, Harri Sivasathiaseelan, Anthipa Chokesuwattanaskul, Annabel Nelson, Ross Nortley, Rimona S Weil, Anna Volkmer, Charles R Marshall, Doris-Eva Bamiou, Jason D Warren, Chris J D Hard. Comprehension of acoustically degraded speech in Alzheimer's disease and primary progressive aphasia. Brain : a journal of neurology. 2023-05-15. PMID:37184986. |
mean noise-vocoded speech intelligibility threshold was significantly higher in all patient groups than healthy controls, and significantly higher in alzheimer's disease and logopenic variant primary progressive aphasia than semantic variant primary progressive aphasia (all p < 0.05). |
2023-05-15 |
2023-08-14 |
human |
| Farah Mgaieth, R Asaad Baksh, Carla M Startin, Sarah Hamburg, Rosalyn Hithersay, Sarah Pape, Henrik Zetterberg, Nicholas J Ashton, Miren Tamayo-Elizalde, Fedal Saini, Mina Idris, The LonDownS Consortium, Andre Strydo. Exploring semantic verbal fluency patterns and their relationship to age and Alzheimer's disease in adults with Down syndrome. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-04-28. PMID:37114906. |
exploring semantic verbal fluency patterns and their relationship to age and alzheimer's disease in adults with down syndrome. |
2023-04-28 |
2023-08-14 |
Not clear |
| Mario F Mendez, Imaad Nasi. Distinguishing Semantic Variant Primary Progressive Aphasia from Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 7. issue 1. 2023-04-24. PMID:37090957. |
distinguishing semantic variant primary progressive aphasia from alzheimer's disease. |
2023-04-24 |
2023-08-14 |
Not clear |