All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Khadga Raj, G D Gupta, Shamsher Sing. Spermine protects aluminium chloride and iron-induced neurotoxicity in rat model of Alzheimer's disease via attenuation of tau phosphorylation, Amyloid-β (1-42) and NF-κB pathway. Inflammopharmacology. vol 29. issue 6. 2021-12-08. PMID:34727278. spermine protects aluminium chloride and iron-induced neurotoxicity in rat model of alzheimer's disease via attenuation of tau phosphorylation, amyloid-β (1-42) and nf-κb pathway. 2021-12-08 2023-08-13 rat
Rebecca M Parodi-Rullán, Sabzali Javadov, Silvia Fossat. Dissecting the Crosstalk between Endothelial Mitochondrial Damage, Vascular Inflammation, and Neurodegeneration in Cerebral Amyloid Angiopathy and Alzheimer's Disease. Cells. vol 10. issue 11. 2021-12-08. PMID:34831125. alzheimer's disease (ad) is the most prevalent cause of dementia and is pathologically characterized by the presence of parenchymal senile plaques composed of amyloid β (aβ) and intraneuronal neurofibrillary tangles of hyperphosphorylated tau protein. 2021-12-08 2023-08-13 Not clear
SpiroAnthony Stathas, Victor E Alvarez, Weiming Xia, Raymond Nicks, Gaoyuan Meng, Sarah Daley, Morgan Pothast, Arsal Shah, Hunter Kelley, Camille Esnault, Robert McCormack, Erin Dixon, Lucas Fishbein, Jonathan D Cherry, Bertrand R Huber, Yorghos Tripodis, Michael L Alosco, Jesse Mez, Ann C McKee, Thor D Stei. Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-12-08. PMID:34854540. tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and alzheimer's disease. 2021-12-08 2023-08-13 Not clear
SpiroAnthony Stathas, Victor E Alvarez, Weiming Xia, Raymond Nicks, Gaoyuan Meng, Sarah Daley, Morgan Pothast, Arsal Shah, Hunter Kelley, Camille Esnault, Robert McCormack, Erin Dixon, Lucas Fishbein, Jonathan D Cherry, Bertrand R Huber, Yorghos Tripodis, Michael L Alosco, Jesse Mez, Ann C McKee, Thor D Stei. Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-12-08. PMID:34854540. post-translation modifications to tau in cte have not been well delineated or compared to alzheimer's disease (ad). 2021-12-08 2023-08-13 Not clear
Viktoriya Zhuravleva, João Vaz-Silva, Mei Zhu, Patricia Gomes, Joana M Silva, Nuno Sousa, Ioannis Sotiropoulos, Clarissa L Waite. Rab35 and glucocorticoids regulate APP and BACE1 trafficking to modulate Aβ production. Cell death & disease. vol 12. issue 12. 2021-12-08. PMID:34876559. chronic stress and elevated glucocorticoids (gcs), the major stress hormones, are risk factors for alzheimer's disease (ad) and promote ad pathomechanisms, including overproduction of toxic amyloid-β (aβ) peptides and intraneuronal accumulation of hyperphosphorylated tau protein. 2021-12-08 2023-08-13 Not clear
Thais Rafael Guimarães, Eric Swanson, Julia Kofler, Amantha Thathia. G protein-coupled receptor kinases are associated with Alzheimer's disease pathology. Neuropathology and applied neurobiology. vol 47. issue 7. 2021-12-07. PMID:34164834. alzheimer's disease (ad) is characterised by extracellular deposition of amyloid-β (aβ) in amyloid plaques and intracellular aggregation and accumulation of hyperphosphorylated tau in neurofibrillary tangles (nfts). 2021-12-07 2023-08-13 Not clear
Gesine Respondek, Lea Krey, Meret Huber, Henning Pflugrad, Florian Wegner, Günter U Höglinge. [Neuroprotective treatment of tauopathies]. Der Nervenarzt. vol 92. issue 12. 2021-12-07. PMID:34652482. these include primary tauopathies, in which tau plays the main role in the pathogenesis as well as secondary tauopathies, such as alzheimer's disease, in which amyloid beta also plays a substantial role in the disease process in addition to the tau pathology. 2021-12-07 2023-08-13 Not clear
Paulino Ramirez, Gabrielle Zuniga, Wenyan Sun, Adrian Beckmann, Elizabeth Ochoa, Sarah L DeVos, Bradley Hyman, Gabriel Chiu, Ethan R Roy, Wei Cao, Miranda Orr, Virginie Buggia-Prevot, William J Ray, Bess Fros. Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system. Progress in neurobiology. 2021-12-07. PMID:34670118. recent studies have identified links between pathogenic forms of tau, a protein that accumulates in alzheimer's disease and related "tauopathies," and transposable element-induced neurotoxicity. 2021-12-07 2023-08-13 mouse
Galina Limorenko, Hilal A Lashue. To target Tau pathologies, we must embrace and reconstruct their complexities. Neurobiology of disease. vol 161. 2021-12-07. PMID:34718129. the accumulation of hyperphosphorylated fibrillar tau aggregates in the brain is one of the defining hallmarks of tauopathy diseases, including alzheimer's disease. 2021-12-07 2023-08-13 Not clear
Emily Hill, Thomas K Karikari, Juan Lantero-Rodriguez, Henrik Zetterberg, Kaj Blennow, Magnus J Richardson, Mark J Wal. Truncating tau reveals different pathophysiological actions of oligomers in single neurons. Communications biology. vol 4. issue 1. 2021-12-07. PMID:34737403. in alzheimer's disease, small numbers of tau molecules can aggregate to form oligomers. 2021-12-07 2023-08-13 human
Sudhir Kshirsagar, Neha Sawant, Hallie Morton, Arubala P Reddy, P Hemachandra Redd. Mitophagy enhancers against phosphorylated Tau-induced mitochondrial and synaptic toxicities in Alzheimer disease. Pharmacological research. vol 174. 2021-12-07. PMID:34763094. the purpose of our study is to determine the protective effects of mitophagy enhancers against phosphorylated tau (p-tau)-induced mitochondrial and synaptic toxicities in alzheimer's disease (ad). 2021-12-07 2023-08-13 mouse
Manuela Piazzi, Alberto Bavelloni, Vittoria Cenni, Irene Faenza, William L Blaloc. Revisiting the Role of GSK3, A Modulator of Innate Immunity, in Idiopathic Inclusion Body Myositis. Cells. vol 10. issue 11. 2021-12-07. PMID:34831477. among the previously examined potential molecular players in ibm is glycogen synthase kinase (gsk)-3, whose role in promoting tau phosphorylation and inclusion bodies in alzheimer's disease is well known. 2021-12-07 2023-08-13 Not clear
Katharina Steiner, Christian Humpe. Microcontact Printing of Cholinergic Neurons in Organotypic Brain Slices. Frontiers in neurology. vol 12. 2021-12-07. PMID:34867765. alzheimer's disease is a severe neurodegenerative disorder of the brain, characterized by beta-amyloid plaques, tau pathology, and cell death of cholinergic neurons, resulting in loss of memory. 2021-12-07 2023-08-13 mouse
Sivaprakasam R Saroja, Abhijeet Sharma, Patrick R Hof, Ana C Pereir. Differential expression of tau species and the association with cognitive decline and synaptic loss in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-12-07. PMID:34873815. differential expression of tau species and the association with cognitive decline and synaptic loss in alzheimer's disease. 2021-12-07 2023-08-13 human
Sivaprakasam R Saroja, Abhijeet Sharma, Patrick R Hof, Ana C Pereir. Differential expression of tau species and the association with cognitive decline and synaptic loss in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-12-07. PMID:34873815. pathological tau proteins in patients with alzheimer's disease (ad) mainly accumulate in the form of neurofibrillary tangles (nfts) and neuritic plaques (nps). 2021-12-07 2023-08-13 human
Kathryn R Bowles, Derian A Pugh, Laura-Maria Oja, Benjamin M Jadow, Kurt Farrell, Kristen Whitney, Abhijeet Sharma, Jonathan D Cherry, Towfique Raj, Ana C Pereira, John F Crary, Alison M Goat. Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD. Acta neuropathologica. 2021-12-07. PMID:34874463. understanding regulation of mapt splicing is important to the etiology of many nerurodegenerative diseases, including alzheimer disease (ad) and progressive supranuclear palsy (psp), in which different tau isoforms accumulate in pathologic inclusions. 2021-12-07 2023-08-13 human
Kaoru Yagita, Hiroyuki Honda, Tomoyuki Ohara, Hideomi Hamasaki, Sachiko Koyama, Hideko Noguchi, Akane Mihara, Taro Nakazawa, Jun Hata, Toshiharu Ninomiya, Toru Iwak. A Comparative Study of Site-Specific Distribution of Aging-Related Tau Astrogliopathy and Its Risk Factors Between Alzheimer Disease and Cognitive Healthy Brains: The Hisayama Study. Journal of neuropathology and experimental neurology. 2021-12-07. PMID:34875089. a comparative study of site-specific distribution of aging-related tau astrogliopathy and its risk factors between alzheimer disease and cognitive healthy brains: the hisayama study. 2021-12-07 2023-08-13 Not clear
Subhalakshmi Guha, Paidi Ramesh Kumar, Soumita Goswami, Pampa Saha, Subhas C Biswa. ICAM-1 protects neurons against Amyloid-β and improves cognitive behaviors in 5xFAD mice by inhibiting NF-κB. Brain, behavior, and immunity. 2021-12-07. PMID:34875346. alzheimer's disease (ad) is mainly characterized by amyloid beta (aβ) plaque deposition and neurofibrillary tangle formation due to tau hyperphosphorylation. 2021-12-07 2023-08-13 mouse
Edmond Teng, Paul T Manser, Sandra Sanabria Bohorquez, Kristin R Wildsmith, Karen Pickthorn, Suzanne L Baker, Michael Ward, Geoffrey A Kerchner, Robby M Weime. Baseline [ Alzheimer's research & therapy. vol 13. issue 1. 2021-12-06. PMID:34852837. baseline [ the role and implementation of tau pet imaging for predicting subsequent cognitive decline in alzheimer's disease (ad) remains uncertain. 2021-12-06 2023-08-13 Not clear
Boris Stephan Rauchmann, Thomas Schneider-Axmann, Robert Perneczk. Associations of longitudinal plasma p-tau181 and NfL with tau-PET, Aβ-PET and cognition. Journal of neurology, neurosurgery, and psychiatry. vol 92. issue 12. 2021-12-05. PMID:34187867. to explore if changes over time of plasma phosphorylated tau (p-tau)181 and neurofilament light chain (nfl) predict future tau and amyloid β (aβ) pet load and cognitive performance, we studied a subsample of the alzheimer's disease (ad) neuroimaging cohort with longitudinal blood peptide assessments. 2021-12-05 2023-08-13 Not clear