| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tammaryn Lashley, Maria-Armineh Tossounian, Neve Costello Heaven, Samantha Wallworth, Sew Peak-Chew, Aaron Bradshaw, J Mark Cooper, Rohan de Silva, Surjit Kaila Srai, Oksana Malanchuk, Valeriy Filonenko, Margreet B Koopman, Stefan G D Rüdiger, Mark Skehel, Ivan Gou. Extensive Anti-CoA Immunostaining in Alzheimer's Disease and Covalent Modification of Tau by a Key Cellular Metabolite Coenzyme A. Frontiers in cellular neuroscience. vol 15. 2021-11-02. PMID:34720880. |
extensive anti-coa immunostaining in alzheimer's disease and covalent modification of tau by a key cellular metabolite coenzyme a. alzheimer's disease (ad) is a neurodegenerative disorder, accounting for at least two-thirds of dementia cases. |
2021-11-02 |
2023-08-13 |
human |
| Liping Fu, Zhi Zhou, Linwen Liu, Jinming Zhang, Hengge Xie, Xiaojun Zhang, Mingwei Zhu, Ruimin Wan. Functional Abnormality Associated With Tau Deposition in Alzheimer's Disease - A Hybrid Positron Emission Tomography/MRI Study. Frontiers in aging neuroscience. vol 13. 2021-11-02. PMID:34721001. |
functional abnormality associated with tau deposition in alzheimer's disease - a hybrid positron emission tomography/mri study. |
2021-11-02 |
2023-08-13 |
Not clear |
| Aqilah Hambali, Jaya Kumar, Nur Fariesha Md Hashim, Sandra Maniam, Muhammad Zulfadli Mehat, Manraj Singh Cheema, Muzaimi Mustapha, Mohd Ilham Adenan, Johnson Stanslas, Hafizah Abdul Hami. Hypoxia-Induced Neuroinflammation in Alzheimer's Disease: Potential Neuroprotective Effects of Frontiers in physiology. vol 12. 2021-11-02. PMID:34721056. |
hypoxia-induced neuroinflammation in alzheimer's disease: potential neuroprotective effects of alzheimer's disease (ad) is a neurodegenerative disorder that is characterised by the presence of extracellular beta-amyloid fibrillary plaques and intraneuronal neurofibrillary tau tangles in the brain. |
2021-11-02 |
2023-08-13 |
Not clear |
| Charles D Chen, Timothy R Holden, Brian A Gordon, Erin E Franklin, Yan Li, Dean W Coble, Hongbo Luo, Randall J Bateman, Beau M Ances, Richard J Perrin, Tammie L S Benzinger, Nigel J Cairns, John C Morri. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease. Annals of clinical and translational neurology. vol 7. issue 12. 2021-11-01. PMID:33150749. |
ante- and postmortem tau in autosomal dominant and late-onset alzheimer's disease. |
2021-11-01 |
2023-08-13 |
Not clear |
| Charles D Chen, Timothy R Holden, Brian A Gordon, Erin E Franklin, Yan Li, Dean W Coble, Hongbo Luo, Randall J Bateman, Beau M Ances, Richard J Perrin, Tammie L S Benzinger, Nigel J Cairns, John C Morri. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease. Annals of clinical and translational neurology. vol 7. issue 12. 2021-11-01. PMID:33150749. |
antemortem tau positron emission tomography imaging suggests elevated tau pathology in autosomal dominant versus late-onset alzheimer's disease at equivalent clinical stages, but does not implicate the specific tau pathologies responsible. |
2021-11-01 |
2023-08-13 |
Not clear |
| Charles D Chen, Timothy R Holden, Brian A Gordon, Erin E Franklin, Yan Li, Dean W Coble, Hongbo Luo, Randall J Bateman, Beau M Ances, Richard J Perrin, Tammie L S Benzinger, Nigel J Cairns, John C Morri. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease. Annals of clinical and translational neurology. vol 7. issue 12. 2021-11-01. PMID:33150749. |
here we made stereological measurements of tau neurofibrillary tangles, neuritic plaques, and neuropil threads and found compared to late-onset alzheimer's disease, autosomal dominant alzheimer's disease showed even greater tangle and thread burdens. |
2021-11-01 |
2023-08-13 |
Not clear |
| Charles D Chen, Timothy R Holden, Brian A Gordon, Erin E Franklin, Yan Li, Dean W Coble, Hongbo Luo, Randall J Bateman, Beau M Ances, Richard J Perrin, Tammie L S Benzinger, Nigel J Cairns, John C Morri. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease. Annals of clinical and translational neurology. vol 7. issue 12. 2021-11-01. PMID:33150749. |
finally, our results suggest tau imaging measures total tau burden in alzheimer's disease, composed predominantly of tangle and thread pathology. |
2021-11-01 |
2023-08-13 |
Not clear |
| Rebecca L Kow, Timothy J Strovas, Pamela J McMillan, Ashley M Jacobi, Mark A Behlke, Aleen D Saxton, Caitlin S Latimer, C Dirk Keene, Brian C Kraeme. Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes. Neurobiology of disease. vol 147. 2021-11-01. PMID:33184027. |
aging drives pathological accumulation of proteins such as tau, causing neurodegenerative dementia disorders like alzheimer's disease. |
2021-11-01 |
2023-08-13 |
mouse |
| Rebecca L Kow, Timothy J Strovas, Pamela J McMillan, Ashley M Jacobi, Mark A Behlke, Aleen D Saxton, Caitlin S Latimer, C Dirk Keene, Brian C Kraeme. Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes. Neurobiology of disease. vol 147. 2021-11-01. PMID:33184027. |
alzheimer's disease patients with low toe1 levels exhibited significantly increased pathological tau deposition and loss of neun staining. |
2021-11-01 |
2023-08-13 |
mouse |
| Anna Siegert, Marija Rankovic, Filippo Favretto, Tina Ukmar-Godec, Timo Strohäker, Stefan Becker, Markus Zweckstette. Interplay between tau and α-synuclein liquid-liquid phase separation. Protein science : a publication of the Protein Society. vol 30. issue 7. 2021-11-01. PMID:33452693. |
liquid-liquid phase separation (llps) of proteins has recently been shown to be important for protein aggregation involved in amyotrophic lateral sclerosis, whereas tau phase separation has been linked to alzheimer's disease. |
2021-11-01 |
2023-08-13 |
Not clear |
| Saeed Najafi, Yanxian Lin, Andrew P Longhini, Xuemei Zhang, Kris T Delaney, Kenneth S Kosik, Glenn H Fredrickson, Joan-Emma Shea, Songi Ha. Liquid-liquid phase separation of Tau by self and complex coacervation. Protein science : a publication of the Protein Society. vol 30. issue 7. 2021-11-01. PMID:33955104. |
the liquid-liquid phase separation (llps) of tau has been postulated to play a role in modulating the aggregation property of tau, a process known to be critically associated with the pathology of a broad range of neurodegenerative diseases including alzheimer's disease. |
2021-11-01 |
2023-08-13 |
Not clear |
| Yuxing Xia, Brach M Bell, Benoit I Giasso. Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau-microtubule interactions and inhibits aggregation. Scientific reports. vol 11. issue 1. 2021-11-01. PMID:34426645. |
alzheimer's disease is the leading cause of dementia and a defining hallmark is the progressive brain deposition of tau aggregates. |
2021-11-01 |
2023-08-13 |
Not clear |
| Analiese R Fernandes, Simon Dujardin, Anastasie Maté de Gérando, Bradley T Hyman, Matthew P Frosc. Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds. Journal of neuropathology and experimental neurology. vol 80. issue 10. 2021-11-01. PMID:34498073. |
for tau species derived from human alzheimer disease tissue (brain homogenate and sarkosyl-insoluble fibrils), both autoclaving and incubation in 90.6% formic acid were sufficient to reduce tau bioactivity. |
2021-11-01 |
2023-08-13 |
mouse |
| Subashchandrabose Chinnathambi, Nalini Vijay Gorantl. Implications of Valosin-containing Protein in Promoting Autophagy to Prevent Tau Aggregation. Neuroscience. vol 476. 2021-11-01. PMID:34509548. |
in the case of tau aggregation associated with alzheimer's disease, the importance of vcp is poorly understood. |
2021-11-01 |
2023-08-13 |
Not clear |
| Zhiyong Zhao, Lei Zhang, Qingqing Wen, Wanrong Luo, Weihao Zheng, Tingting Liu, Yi Zhang, Keqing Zhu, Dan W. The effect of beta-amyloid and tau protein aggregations on magnetic susceptibility of anterior hippocampal laminae in Alzheimer's diseases. NeuroImage. vol 244. 2021-11-01. PMID:34537383. |
the effect of beta-amyloid and tau protein aggregations on magnetic susceptibility of anterior hippocampal laminae in alzheimer's diseases. |
2021-11-01 |
2023-08-13 |
Not clear |
| M Senda, K Ishii, K Ito, T Ikeuchi, H Matsuda, T Iwatsubo, A Iwata, R Ihara, K Suzuki, K Kasuga, Y Ikari, Y Niimi, H Arai, A Tamaoka, Y Arahata, Y Itoh, H Tachibana, Y Ichimiya, S Washizuka, T Odawara, K Ishii, K Ono, T Yokota, A Nakanishi, E Matsubara, H Mori, H Shimad. A Japanese Multicenter Study on PET and Other Biomarkers for Subjects with Potential Preclinical and Prodromal Alzheimer's Disease. The journal of prevention of Alzheimer's disease. vol 8. issue 4. 2021-11-01. PMID:34585225. |
pet (positron emission tomography) and csf (cerebrospinal fluid) provide the "atn" (amyloid, tau, neurodegeneration) classification and play an essential role in early and differential diagnosis of alzheimer's disease (ad). |
2021-11-01 |
2023-08-13 |
human |
| Anis Barati, Raheleh Masoudi, Reza Yousefi, Malihezaman Monsefi, Abbas Mirshafie. Tau and amyloid beta differentially affect the innate immune genes expression in Drosophila models of Alzheimer's disease and β- D Mannuronic acid (M2000) modulates the dysregulation. Gene. vol 808. 2021-11-01. PMID:34600048. |
tau and amyloid beta differentially affect the innate immune genes expression in drosophila models of alzheimer's disease and β- d mannuronic acid (m2000) modulates the dysregulation. |
2021-11-01 |
2023-08-13 |
drosophila_melanogaster |
| Mehdi Shojaie, Solale Tabarestani, Mercedes Cabrerizo, Steven T DeKosky, David E Vaillancourt, David Loewenstein, Ranjan Duara, Malek Adjouad. PET Imaging of Tau Pathology and Amyloid-β, and MRI for Alzheimer's Disease Feature Fusion and Multimodal Classification. Journal of Alzheimer's disease : JAD. 2021-11-01. PMID:34719488. |
pet imaging of tau pathology and amyloid-β, and mri for alzheimer's disease feature fusion and multimodal classification. |
2021-11-01 |
2023-08-13 |
Not clear |
| Christiana Bjorkli, Claire Louet, Trude Helen Flo, Mary Hemler, Axel Sandvig, Ioanna Sandvi. In Vivo Microdialysis in Mice Captures Changes in Alzheimer's Disease Cerebrospinal Fluid Biomarkers Consistent with Developing Pathology. Journal of Alzheimer's disease : JAD. 2021-11-01. PMID:34719495. |
preclinical models of alzheimer's disease (ad) can provide valuable insights into the onset and progression of the disease, such as changes in concentrations of amyloid-β (aβ) and tau in cerebrospinal fluid (csf). |
2021-11-01 |
2023-08-13 |
mouse |
| Angie K Torres, Claudia Jara, Han S Park-Kang, Catalina M Polanco, Diego Tapia, Fabián Alarcón, Adely de la Peña, Jesus Llanquinao, Gabriela Vargas-Mardones, Javiera A Indo, Nibaldo C Inestrosa, Cheril Tapia-Roja. Synaptic Mitochondria: An Early Target of Amyloid-β and Tau in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2021-11-01. PMID:34719499. |
synaptic mitochondria: an early target of amyloid-β and tau in alzheimer's disease. |
2021-11-01 |
2023-08-13 |
Not clear |