All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Kyra Ungerleider, Jessica Beck, Delphine Lissa, Casmir Turnquist, Izumi Horikawa, Brent T Harris, Curtis C Harri. Astrocyte senescence and SASP in neurodegeneration: tau joins the loop. Cell cycle (Georgetown, Tex.). vol 20. issue 8. 2021-09-23. PMID:33818291. tau accumulation is a core component of alzheimer's disease and other neurodegenerative tauopathies. 2021-09-23 2023-08-13 human
Tzayaka Castillo-Mendieta, Yoaly Arana-Lechuga, Victoria Campos-Peña, Ana Luisa Sosa, Sandra Orozco-Suarez, Rodolfo Pinto-Almazán, Julia Segura-Uribe, Aldo Javier Rodríguez-Sánchez de Tagle, Elizabeth Ruiz-Sánchez, Christian Guerra-Araiz. Plasma Levels of Amyloid-β Peptides and Tau Protein in Mexican Patients with Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 82. issue s1. 2021-09-23. PMID:34151786. plasma levels of amyloid-β peptides and tau protein in mexican patients with alzheimer's disease. 2021-09-23 2023-08-13 Not clear
Miranda Robbins, Emma Clayton, Gabriele S Kaminski Schierl. Synaptic tau: A pathological or physiological phenomenon? Acta neuropathologica communications. vol 9. issue 1. 2021-09-22. PMID:34503576. in this review, we discuss the synaptic aspects of tau pathology occurring during alzheimer's disease (ad) and how this may relate to memory impairment, a major hallmark of ad. 2021-09-22 2023-08-13 Not clear
Argyro Thalia Delizannis, Annelies Nonneman, Wangchen Tsering, An De Bondt, Ilse Van den Wyngaert, Bin Zhang, Emily Meymand, Modupe F Olufemi, Pyry Koivula, Shaniya Maimaiti, John Q Trojanowski, Virginia M-Y Lee, Kurt R Brunde. Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice. Acta neuropathologica communications. vol 9. issue 1. 2021-09-22. PMID:34503586. dystrophic neuronal processes harboring neuritic plaque (np) tau pathology are found in association with aβ plaques in alzheimer's disease (ad) brain. 2021-09-22 2023-08-13 mouse
Nils Korte, Ross Nortley, David Attwel. Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease. Acta neuropathologica. vol 140. issue 6. 2021-09-21. PMID:32865691. therapies targeting late events in alzheimer's disease (ad), including aggregation of amyloid beta (aβ) and hyperphosphorylated tau, have largely failed, probably because they are given after significant neuronal damage has occurred. 2021-09-21 2023-08-13 Not clear
Takashi Kubota, Yutaka Kirin. Age-dependent impairment of memory and neurofibrillary tangle formation and clearance in a mouse model of tauopathy. Brain research. vol 1765. 2021-09-21. PMID:33894222. insoluble, fibrillar intraneuronal accumulation of the tau protein termed neurofibrillary tangles (nfts), are characteristic hallmarks of alzheimer's disease (ad). 2021-09-21 2023-08-13 mouse
Sun Sang Kwon, Dongwoo Kim, Mijin Yun, Jeong Gon Son, Soo Hyun Le. The role of graphene patterning in field-effect transistor sensors to detect the tau protein for Alzheimer's disease: Simplifying the immobilization process and improving the performance of graphene-based immunosensors. Biosensors & bioelectronics. vol 192. 2021-09-21. PMID:34333316. the role of graphene patterning in field-effect transistor sensors to detect the tau protein for alzheimer's disease: simplifying the immobilization process and improving the performance of graphene-based immunosensors. 2021-09-21 2023-08-13 Not clear
Sun Sang Kwon, Dongwoo Kim, Mijin Yun, Jeong Gon Son, Soo Hyun Le. The role of graphene patterning in field-effect transistor sensors to detect the tau protein for Alzheimer's disease: Simplifying the immobilization process and improving the performance of graphene-based immunosensors. Biosensors & bioelectronics. vol 192. 2021-09-21. PMID:34333316. moreover, tau protein in the plasma of five alzheimer's disease patients was measured using a linker-free patterned graphene sensor. 2021-09-21 2023-08-13 Not clear
Natália Chermont Dos Santos Moreira, Jéssica Ellen Barbosa de Freitas Lima, Talita Perez Cantuaria Chierrito, Ivone Carvalho, Elza Tiemi Sakamoto-Hoj. Novel Hybrid Acetylcholinesterase Inhibitors Induce Differentiation and Neuritogenesis in Neuronal Cells in vitro Through Activation of the AKT Pathway. Journal of Alzheimer's disease : JAD. vol 78. issue 1. 2021-09-20. PMID:32986667. alzheimer's disease (ad) is characterized by a progressive loss of episodic memory associated with amyloid-β peptide aggregation and the abnormal phosphorylation of the tau protein, leading to the loss of cholinergic function. 2021-09-20 2023-08-13 Not clear
Rui-Qi Zhang, Shi-Dong Chen, Xue-Ning Shen, Yu-Xiang Yang, Jia-Ying Lu, Mei Cui, Chuan-Tao Zuo, Qiang Dong, Lan Tan, Jin-Tai Y. Elevated Tau PET Signal Depends on Abnormal Amyloid Levels and Correlates with Cognitive Impairment in Elderly Persons without Dementia. Journal of Alzheimer's disease : JAD. vol 78. issue 1. 2021-09-20. PMID:32986669. the recent developed pet ligands for amyloid-β (aβ) and tau allow these two neuropathological hallmarks of alzheimer's disease (ad) to be mapped and quantified in vivo and to be examined in relation to cognition. 2021-09-20 2023-08-13 Not clear
Josh King-Robson, Heather Wilson, Marios Politi. Associations Between Amyloid and Tau Pathology, and Connectome Alterations, in Alzheimer's Disease and Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD. vol 82. issue 2. 2021-09-20. PMID:34057079. associations between amyloid and tau pathology, and connectome alterations, in alzheimer's disease and mild cognitive impairment. 2021-09-20 2023-08-13 Not clear
Josh King-Robson, Heather Wilson, Marios Politi. Associations Between Amyloid and Tau Pathology, and Connectome Alterations, in Alzheimer's Disease and Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD. vol 82. issue 2. 2021-09-20. PMID:34057079. the roles of amyloid-β and tau in the degenerative process of alzheimer's disease (ad) remain uncertain. 2021-09-20 2023-08-13 Not clear
Nikita Das, James Raymick, Sumit Sarka. Role of metals in Alzheimer's disease. Metabolic brain disease. vol 36. issue 7. 2021-09-20. PMID:34313926. this review covers mechanisms of action of aluminum, iron, copper, and zinc ions with respect to the progressive, toxic accumulation of extracellular β-amyloid plaques and intracellular hyperphosphorylated neurofibrillary tau tangles that characterizes alzheimer's disease, with the goal of evaluating the therapeutic potential of metal ion interference in neurodegenerative disease prevention and treatment. 2021-09-20 2023-08-13 Not clear
Patrik Oleksak, Michal Novotny, Jiri Patocka, Eugenie Nepovimova, Jakub Hort, Jan Pavlik, Blanka Klimova, Martin Valis, Kamil Kuc. Neuropharmacology of Cevimeline and Muscarinic Drugs-Focus on Cognition and Neurodegeneration. International journal of molecular sciences. vol 22. issue 16. 2021-09-20. PMID:34445613. furthermore, it has demonstrated to positively influence tau pathology and reduce the levels of amyloid-β (aβ) peptide in the cerebral spinal fluid of alzheimer's patients. 2021-09-20 2023-08-13 Not clear
Yang Zhou, Junhao Li, Agneta Nordberg, Hans Ågre. Dissecting the Binding Profile of PET Tracers to Corticobasal Degeneration Tau Fibrils. ACS chemical neuroscience. vol 12. issue 18. 2021-09-20. PMID:34464084. alzheimer's disease and primary tauopathies are characterized by the presence of tau pathology in brain. 2021-09-20 2023-08-13 Not clear
Yang Zhou, Junhao Li, Agneta Nordberg, Hans Ågre. Dissecting the Binding Profile of PET Tracers to Corticobasal Degeneration Tau Fibrils. ACS chemical neuroscience. vol 12. issue 18. 2021-09-20. PMID:34464084. several tau positron emission tomography (pet) tracers have been developed and studied in alzheimer's disease (ad), but there is still a lack of 4r-tau specific tracers for non-ad tauopathies. 2021-09-20 2023-08-13 Not clear
Shulan Qiu, Juan Pablo Palavicini, Jianing Wang, Nancy S Gonzalez, Sijia He, Elizabeth Dustin, Cheng Zou, Lin Ding, Anindita Bhattacharjee, Candice E Van Skike, Veronica Galvan, Jeffrey L Dupree, Xianlin Ha. Adult-onset CNS myelin sulfatide deficiency is sufficient to cause Alzheimer's disease-like neuroinflammation and cognitive impairment. Molecular neurodegeneration. vol 16. issue 1. 2021-09-20. PMID:34526055. human genetic association studies point to immune response and lipid metabolism, in addition to amyloid-beta (aβ) and tau, as major pathways in alzheimer's disease (ad) etiology. 2021-09-20 2023-08-13 human
Yee Fun Lee, Dmitry Gerashchenko, Igor Timofeev, Brian J Bacskai, Ksenia V Kastanenk. Slow Wave Sleep Is a Promising Intervention Target for Alzheimer's Disease. Frontiers in neuroscience. vol 14. 2021-09-18. PMID:32714142. alzheimer's disease (ad) is the major cause of dementia, characterized by the presence of amyloid-beta plaques and neurofibrillary tau tangles. 2021-09-18 2023-08-13 mouse
Conrad N Trumbor. Shear-Induced Amyloid Aggregation in the Brain: V. Are Alzheimer's and Other Amyloid Diseases Initiated in the Lower Brain and Brainstem by Cerebrospinal Fluid Flow Stresses? Journal of Alzheimer's disease : JAD. vol 79. issue 3. 2021-09-17. PMID:33386802. amyloid-β (aβ) and tau oligomers have been identified as neurotoxic agents responsible for causing alzheimer's disease (ad). 2021-09-17 2023-08-13 Not clear
Christopher Gonzalez, Nicole S Tommasi, Danielle Briggs, Michael J Properzi, Rebecca E Amariglio, Gad A Marshal. Financial Capacity and Regional Cerebral Tau in Cognitively Normal Older Adults, Mild Cognitive Impairment, and Alzheimer's Disease Dementia. Journal of Alzheimer's disease : JAD. vol 79. issue 3. 2021-09-17. PMID:33386806. financial capacity and regional cerebral tau in cognitively normal older adults, mild cognitive impairment, and alzheimer's disease dementia. 2021-09-17 2023-08-13 Not clear