| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joseph Seemiller, Gérard N Bischof, Merle C Hoenig, Masoud Tahmasian, Thilo van Eimeren, Alexander Drzezg. Indication of retrograde tau spreading along Braak stages and functional connectivity pathways. European journal of nuclear medicine and molecular imaging. vol 48. issue 7. 2021-06-25. PMID:33462630. |
tau pathology progression in alzheimer's disease (ad) is explained through the network degeneration hypothesis and the neuropathological braak stages; however, the compatibility of these models remains unclear. |
2021-06-25 |
2023-08-13 |
Not clear |
| Gemma Salvadó, Michel J Grothe, Colin Groot, Alexis Moscoso, Michael Schöll, Juan Domingo Gispert, Rik Ossenkoppel. Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia. European journal of nuclear medicine and molecular imaging. vol 48. issue 7. 2021-06-25. PMID:33521872. |
to examine associations between the apoe-ε2 and apoe-ε4 alleles and core alzheimer's disease (ad) pathological hallmarks as measured by amyloid-β (aβ) and tau pet in older individuals without dementia. |
2021-06-25 |
2023-08-13 |
Not clear |
| Gérard N Bischof, Alessandra Dodich, Marina Boccardi, Thilo van Eimeren, Cristina Festari, Henryk Barthel, Oskar Hansson, Agneta Nordberg, Rik Ossenkoppele, Osama Sabri, B Frisoni G Giovanni, Valentina Garibotto, Alexander Drzezg. Clinical validity of second-generation tau PET tracers as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework. European journal of nuclear medicine and molecular imaging. vol 48. issue 7. 2021-06-25. PMID:33590274. |
clinical validity of second-generation tau pet tracers as biomarkers for alzheimer's disease in the context of a structured 5-phase development framework. |
2021-06-25 |
2023-08-13 |
Not clear |
| A Leuzy, N J Ashton, N Mattsson-Carlgren, A Dodich, M Boccardi, J Corre, A Drzezga, A Nordberg, R Ossenkoppele, H Zetterberg, K Blennow, G B Frisoni, V Garibotto, O Hansso. 2020 update on the clinical validity of cerebrospinal fluid amyloid, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework. European journal of nuclear medicine and molecular imaging. vol 48. issue 7. 2021-06-25. PMID:33674895. |
2020 update on the clinical validity of cerebrospinal fluid amyloid, tau, and phospho-tau as biomarkers for alzheimer's disease in the context of a structured 5-phase development framework. |
2021-06-25 |
2023-08-13 |
Not clear |
| N J Ashton, A Leuzy, T K Karikari, N Mattsson-Carlgren, A Dodich, M Boccardi, J Corre, A Drzezga, A Nordberg, R Ossenkoppele, H Zetterberg, K Blennow, G B Frisoni, V Garibotto, O Hansso. The validation status of blood biomarkers of amyloid and phospho-tau assessed with the 5-phase development framework for AD biomarkers. European journal of nuclear medicine and molecular imaging. vol 48. issue 7. 2021-06-25. PMID:33677733. |
the development of blood biomarkers that reflect alzheimer's disease (ad) pathophysiology (phosphorylated tau and amyloid-β) has offered potential as scalable tests for dementia differential diagnosis and early detection. |
2021-06-25 |
2023-08-13 |
Not clear |
| Konstantinos Chiotis, Alessandra Dodich, Marina Boccardi, Cristina Festari, Alexander Drzezga, Oskar Hansson, Rik Ossenkoppele, Giovanni Frisoni, Valentina Garibotto, Agneta Nordber. Clinical validity of increased cortical binding of tau ligands of the THK family and PBB3 on PET as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework. European journal of nuclear medicine and molecular imaging. vol 48. issue 7. 2021-06-25. PMID:33723628. |
clinical validity of increased cortical binding of tau ligands of the thk family and pbb3 on pet as biomarkers for alzheimer's disease in the context of a structured 5-phase development framework. |
2021-06-25 |
2023-08-13 |
Not clear |
| Eli J Cornblath, Howard L Li, Lakshmi Changolkar, Bin Zhang, Hannah J Brown, Ronald J Gathagan, Modupe F Olufemi, John Q Trojanowski, Danielle S Bassett, Virginia M Y Lee, Michael X Henderso. Computational modeling of tau pathology spread reveals patterns of regional vulnerability and the impact of a genetic risk factor. Science advances. vol 7. issue 24. 2021-06-25. PMID:34108219. |
neuropathological staging studies have suggested that tau pathology spreads through the brain in alzheimer's disease (ad) and other tauopathies, but it is unclear how neuroanatomical connections, spatial proximity, and regional vulnerability contribute. |
2021-06-25 |
2023-08-13 |
mouse |
| Meng-Shan Tan, Xi Ji, Jie-Qiong Li, Wei Xu, Hui-Fu Wang, Chen-Chen Tan, Qiang Dong, Chuan-Tao Zuo, Lan Tan, John Suckling, Jin-Tai Y. Longitudinal trajectories of Alzheimer's ATN biomarkers in elderly persons without dementia. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32393375. |
models of alzheimer's disease (ad) pathophysiology posit that amyloidosis [a] precedes and accelerates tau pathology [t] that leads to neurodegeneration [n]. |
2021-06-24 |
2023-08-13 |
Not clear |
| Caitlin N Suire, Samer O Abdul-Hay, Tomoko Sahara, Dongcheul Kang, Monica K Brizuela, Paul Saftig, Dennis W Dickson, Terrone L Rosenberry, Malcolm A Leissrin. Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32631408. |
cathepsin d (catd) is a lysosomal protease that degrades both the amyloid β-protein (aβ) and the microtubule-associated protein, tau, and has been genetically linked to late-onset alzheimer disease (ad). |
2021-06-24 |
2023-08-13 |
Not clear |
| Kyu Hwan Shim, Min Ju Kang, Jee Won Suh, Jung-Min Pyun, Nayoung Ryoo, Young Ho Park, Young Chul Youn, Jae-Won Jang, Jee Hyang Jeong, Kyung Won Park, Seong Hye Choi, Kyoungho Suk, Ho-Won Lee, Pan-Woo Ko, Chan-Nyoung Lee, Tae-Sung Lim, Seong Soo A An, SangYun Ki. CSF total tau/α-synuclein ratio improved the diagnostic performance for Alzheimer's disease as an indicator of tau phosphorylation. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32660565. |
csf total tau/α-synuclein ratio improved the diagnostic performance for alzheimer's disease as an indicator of tau phosphorylation. |
2021-06-24 |
2023-08-13 |
Not clear |
| Ian Fyf. Tau species has potential for Alzheimer disease blood test. Nature reviews. Neurology. vol 16. issue 10. 2021-06-24. PMID:32792665. |
tau species has potential for alzheimer disease blood test. |
2021-06-24 |
2023-08-13 |
Not clear |
| Tengfei Guo, Deniz Korman, Renaud La Joie, Leslie M Shaw, John Q Trojanowski, William J Jagust, Susan M Landa. Normalization of CSF pTau measurement by Aβ Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32799929. |
normalization of csf ptau measurement by aβ alzheimer's disease (ad)-related tauopathy can be measured with csf phosphorylated tau (ptau) and tau pet. |
2021-06-24 |
2023-08-13 |
Not clear |
| Daniel J Norton, Mario A Parra, Reisa A Sperling, Ana Baena, Edmarie Guzman-Velez, David S Jin, Nicholas Andrea, Juna Khang, Aaron Schultz, Dorene M Rentz, Enmanuelle Pardilla-Delgado, Joshua Fuller, Keith Johnson, Eric M Reiman, Francisco Lopera, Yakeel T Quiro. Visual short-term memory relates to tau and amyloid burdens in preclinical autosomal dominant Alzheimer's disease. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32825838. |
visual short-term memory relates to tau and amyloid burdens in preclinical autosomal dominant alzheimer's disease. |
2021-06-24 |
2023-08-13 |
Not clear |
| Hanna Cho, Min Seok Baek, Hye Sun Lee, Jae Hoon Lee, Young Hoon Ryu, Chul Hyoung Lyo. Principal components of tau positron emission tomography and longitudinal tau accumulation in Alzheimer's disease. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32967721. |
principal components of tau positron emission tomography and longitudinal tau accumulation in alzheimer's disease. |
2021-06-24 |
2023-08-13 |
Not clear |
| Hanna Cho, Min Seok Baek, Hye Sun Lee, Jae Hoon Lee, Young Hoon Ryu, Chul Hyoung Lyo. Principal components of tau positron emission tomography and longitudinal tau accumulation in Alzheimer's disease. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:32967721. |
we aimed to investigate the clinical correlates of principal components (pcs) of tau positron emission tomography (pet) and their predictability for longitudinal changes in tau accumulation in alzheimer's disease (ad). |
2021-06-24 |
2023-08-13 |
Not clear |
| Anna Rubinski, Nicolai Franzmeier, Julia Neitzel, Michael Ewer. FDG-PET hypermetabolism is associated with higher tau-PET in mild cognitive impairment at low amyloid-PET levels. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:33076977. |
fdg-pet hypermetabolism can be observed in mild cognitive impairment (mci), but the link to primary pathologies of alzheimer's diseases (ad) including amyloid and tau is unclear. |
2021-06-24 |
2023-08-13 |
Not clear |
| Min Seok Baek, Hanna Cho, Hye Sun Lee, Jae Hoon Lee, Young Hoon Ryu, Chul Hyoung Lyo. Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer's disease. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:33129364. |
effect of apoe ε4 genotype on amyloid-β and tau accumulation in alzheimer's disease. |
2021-06-24 |
2023-08-13 |
Not clear |
| Min Seok Baek, Hanna Cho, Hye Sun Lee, Jae Hoon Lee, Young Hoon Ryu, Chul Hyoung Lyo. Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer's disease. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:33129364. |
to assess the effects of apolipoprotein e (apoe) ε4 genotype on amyloid-β (aβ) and tau burden and their longitudinal changes in alzheimer's disease (ad) spectrum. |
2021-06-24 |
2023-08-13 |
Not clear |
| Filippo Baldacci, Simone Lista, Maria Laura Manca, Patrizia A Chiesa, Enrica Cavedo, Pablo Lemercier, Henrik Zetterberg, Kaj Blennow, Marie-Odile Habert, Marie Claude Potier, Bruno Dubois, Andrea Vergallo, Harald Hampe. Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study. Alzheimer's research & therapy. vol 12. issue 1. 2021-06-24. PMID:33183357. |
plasma neurofilament light (nfl) and total tau (t-tau) proteins are candidate biomarkers for early stages of alzheimer's disease (ad). |
2021-06-24 |
2023-08-13 |
Not clear |
| Nicole D Anderson, Elsa Beana, Haopei Yang, Stefan Köhle. Deficits in recent but not lifetime familiarity in amnestic mild cognitive impairment. Neuropsychologia. vol 151. 2021-06-24. PMID:33359882. |
accumulation of neurofibrillary tau in preclinical alzheimer's disease begins in perirhinal cortex, a medial temporal lobe region linked to familiarity. |
2021-06-24 |
2023-08-13 |
Not clear |