All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Jinwang Ye, Huali Wan, Sihua Chen, Gong-Ping Li. Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy. Neural regeneration research. vol 19. issue 7. 2023-12-05. PMID:38051891. targeting tau in alzheimer's disease: from mechanisms to clinical therapy. 2023-12-05 2023-12-10 Not clear
Jinwang Ye, Huali Wan, Sihua Chen, Gong-Ping Li. Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy. Neural regeneration research. vol 19. issue 7. 2023-12-05. PMID:38051891. primary features of alzheimer's disease include extracellular aggregation of amyloid-β plaques and the accumulation of neurofibrillary tangles, formed by tau protein, in the cells. 2023-12-05 2023-12-10 Not clear
Jinwang Ye, Huali Wan, Sihua Chen, Gong-Ping Li. Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy. Neural regeneration research. vol 19. issue 7. 2023-12-05. PMID:38051891. mounting evidence suggests significant involvement of tau protein in alzheimer's disease-related neurodegeneration. 2023-12-05 2023-12-10 Not clear
Jinwang Ye, Huali Wan, Sihua Chen, Gong-Ping Li. Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy. Neural regeneration research. vol 19. issue 7. 2023-12-05. PMID:38051891. various therapeutic strategies targeting tau protein have begun to emerge, and are considered possible methods to prevent and treat alzheimer's disease. 2023-12-05 2023-12-10 Not clear
Jinwang Ye, Huali Wan, Sihua Chen, Gong-Ping Li. Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy. Neural regeneration research. vol 19. issue 7. 2023-12-05. PMID:38051891. this review summarizes the recent findings on the underlying mechanisms of tau protein in the onset and progression of alzheimer's disease and discusses tau-targeted treatment of alzheimer's disease. 2023-12-05 2023-12-10 Not clear
Gustavo Patow, Leon Stefanovski, Petra Ritter, Gustavo Deco, Xenia Kobelev. Whole-brain modeling of the differential influences of amyloid-beta and tau in Alzheimer's disease. Alzheimer's research & therapy. vol 15. issue 1. 2023-12-05. PMID:38053164. whole-brain modeling of the differential influences of amyloid-beta and tau in alzheimer's disease. 2023-12-05 2023-12-10 Not clear
Gustavo Patow, Leon Stefanovski, Petra Ritter, Gustavo Deco, Xenia Kobelev. Whole-brain modeling of the differential influences of amyloid-beta and tau in Alzheimer's disease. Alzheimer's research & therapy. vol 15. issue 1. 2023-12-05. PMID:38053164. alzheimer's disease is a neurodegenerative condition associated with the accumulation of two misfolded proteins, amyloid-beta (a[formula: see text]) and tau. 2023-12-05 2023-12-10 Not clear
Anna Rubinski, Anna Dewenter, Lukai Zheng, Nicolai Franzmeier, Henry Stephenson, Yuetiva Deming, Marco Duering, Benno Gesierich, Jannis Denecke, An-Vi Pham, Barbara Bendlin, Michael Ewer. Florbetapir PET-assessed demyelination is associated with faster tau accumulation in an APOE ε4-dependent manner. European journal of nuclear medicine and molecular imaging. 2023-12-04. PMID:38049659. the main objectives were to test whether (1) a decrease in myelin is associated with enhanced rate of fibrillar tau accumulation and cognitive decline in alzheimer's disease, and (2) whether apolipoprotein e (apoe) ε4 genotype is associated with worse myelin decrease and thus tau accumulation. 2023-12-04 2023-12-10 Not clear
Carolyn Tallon, Benjamin J Bell, Medhinee M Malvankar, Pragney Deme, Carlos Nogueras-Ortiz, Erden Eren, Ajit G Thomas, Kristen R Hollinger, Arindom Pal, Maja Mustapic, Meixiang Huang, Kaleem Coleman, Tawnjerae R Joe, Rana Rais, Norman J Haughey, Dimitrios Kapogiannis, Barbara S Slushe. Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer's disease mouse model. Translational neurodegeneration. vol 12. issue 1. 2023-12-04. PMID:38049923. cognitive decline in alzheimer's disease (ad) is associated with hyperphosphorylated tau (ptau) propagation between neurons along synaptically connected networks, in part via extracellular vesicles (evs). 2023-12-04 2023-12-10 mouse
Ye Wang, Yuhan Zhang, Enyan Y. Targeted examination of amyloid beta and tau protein accumulation via positron emission tomography for the differential diagnosis of Alzheimer's disease based on the A/T(N) research framework. Clinical neurology and neurosurgery. vol 236. 2023-12-03. PMID:38043158. targeted examination of amyloid beta and tau protein accumulation via positron emission tomography for the differential diagnosis of alzheimer's disease based on the a/t(n) research framework. 2023-12-03 2023-12-10 Not clear
Min Hu, Xinyi Ying, Miao Zheng, Can Wang, Qin Li, G U Lili, Xinyue Zhan. Therapeutic potential of natural products against Alzheimer's disease via autophagic removal of Aβ. Brain research bulletin. 2023-12-03. PMID:38043648. the pathological features of alzheimer's disease (ad), a progressive neurodegenerative disorder, include the deposition of extracellular amyloid beta (aβ) plaques and intracellular tau neurofibrillary tangles. 2023-12-03 2023-12-10 Not clear
Yunfeng Li, Xiongjin Chen, Mulan Zhou, Sifan Feng, Xiaoping Peng, Yan Wan. Microglial TLR4/NLRP3 Inflammasome Signaling in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-12-03. PMID:38043010. the accumulation of extracellular amyloid-β (aβ), intracellular neurofibrillary tangles formed by tau hyperphosphorylation, and neuroinflammation are the major pathological features of alzheimer's disease (ad). 2023-12-03 2023-12-10 Not clear
Bide Zhang, Vanessa Lage-Rupprecht, Philipp Wegner, Astghik Sargsyan, Stephan Gebel, Marc Jacobs, Jürgen Klein, Martin Hofmann-Apitius, Alpha Tom Kodamulli. Design of the formalized and integrated Alzheimer's Disease Ontology and its application in retrieving textual data via text mining. Database : the journal of biological databases and curation. vol 2023. 2023-12-02. PMID:38041858. as one of the leading causes for dementia in the population, it is imperative that we discern exactly why alzheimer's disease (ad) has a strong molecular association with beta-amyloid and tau. 2023-12-02 2023-12-10 Not clear
Jean-Pierre Bellier, Yuqi Cai, Sarah M Alam, Thorsten Wiederhold, Arica Aiello, Jonathan S Vogelgsang, Sabina Berretta, Jasmeer P Chhatwal, Dennis J Selkoe, Lei Li. Uncovering elevated tau TPP motif phosphorylation in the brain of Alzheimer's disease patients. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-12-02. PMID:38041855. uncovering elevated tau tpp motif phosphorylation in the brain of alzheimer's disease patients. 2023-12-02 2023-12-10 Not clear
Jean-Pierre Bellier, Yuqi Cai, Sarah M Alam, Thorsten Wiederhold, Arica Aiello, Jonathan S Vogelgsang, Sabina Berretta, Jasmeer P Chhatwal, Dennis J Selkoe, Lei Li. Uncovering elevated tau TPP motif phosphorylation in the brain of Alzheimer's disease patients. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-12-02. PMID:38041855. a wide array of post-translational modifications of the tau protein occurs in alzheimer's disease (ad) and they are critical to pathogenesis and biomarker development. 2023-12-02 2023-12-10 Not clear
Yanting Chen, Yanfang He, Jinling Han, Wenyan Wei, Feng Che. Blood-brain barrier dysfunction and Alzheimer's disease: associations, pathogenic mechanisms, and therapeutic potential. Frontiers in aging neuroscience. vol 15. 2023-12-01. PMID:38020775. alzheimer's disease (ad) is a common neurodegenerative disorder characterized by the accumulation of amyloid-beta (aβ), hyperphosphorylation of tau, and neuroinflammation in the brain. 2023-12-01 2023-12-10 Not clear
Haleh Barmaki, Alireza Nourazarian, Fatemeh Khaki-Khatib. Proteostasis and neurodegeneration: a closer look at autophagy in Alzheimer's disease. Frontiers in aging neuroscience. vol 15. 2023-12-01. PMID:38020769. alzheimer's disease (ad) is characterized by the accumulation of misfolded amyloid-beta and tau proteins. 2023-12-01 2023-12-10 Not clear
Wendi Huang, Juan Huang, Nanqu Huang, Yong Lu. The role of TREM2 in Alzheimer's disease: from the perspective of Tau. Frontiers in cell and developmental biology. vol 11. 2023-12-01. PMID:38020891. the role of trem2 in alzheimer's disease: from the perspective of tau. 2023-12-01 2023-12-10 Not clear
Huiying Yan, Lina Feng, Mingquan L. The Role of Traditional Chinese Medicine Natural Products in β-Amyloid Deposition and Tau Protein Hyperphosphorylation in Alzheimer's Disease. Drug design, development and therapy. vol 17. 2023-12-01. PMID:38024535. the role of traditional chinese medicine natural products in β-amyloid deposition and tau protein hyperphosphorylation in alzheimer's disease. 2023-12-01 2023-12-10 Not clear
Greet Vanderlinden, Laura Michiels, Michel Koole, Robin Lemmens, Dirk Liessens, Jan Van Walleghem, Bart Depreitere, Mathieu Vandenbulcke, Koen Van Laer. Tau imaging in late traumatic brain injury: a [ Journal of neurotrauma. 2023-12-01. PMID:38038357. tau imaging in late traumatic brain injury: a [ epidemiological studies have identified prior traumatic brain injury (tbi) as a risk factor for developing alzheimer's disease (ad). 2023-12-01 2023-12-10 Not clear