| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nalini V Gorantla, Rashmi Das, Fayaj A Mulani, Hirekodathakallu V Thulasiram, Subashchandrabose Chinnathamb. Neem Derivatives Inhibits Tau Aggregation. Journal of Alzheimer's disease reports. vol 3. issue 1. 2021-05-13. PMID:31259310. |
alzheimer's disease pathology triggers several modifications in tau, which causes it to lose its affinity towards microtubule, thus, leading to microtubule disassembly and loss of axonal integrity. |
2021-05-13 |
2023-08-13 |
Not clear |
| Kelly Ceyzériat, Benjamin B Tournier, Philippe Millet, Giovanni B Frisoni, Valentina Garibotto, Thomas Zill. Low-Dose Radiation Therapy: A New Treatment Strategy for Alzheimer's Disease? Journal of Alzheimer's disease : JAD. vol 74. issue 2. 2021-05-13. PMID:32039848. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by extracellular amyloid-β (aβ) peptide aggregates, forming amyloid plaques, and intracellular deposits of phosphorylated tau. |
2021-05-13 |
2023-08-13 |
Not clear |
| Claudio Liguori, Matteo Spanetta, Francesca Izzi, Flaminia Franchini, Marzia Nuccetelli, Giulia Maria Sancesario, Simona Di Santo, Sergio Bernardini, Nicola Biagio Mercuri, Fabio Placid. Sleep-Wake Cycle in Alzheimer's Disease Is Associated with Tau Pathology and Orexin Dysregulation. Journal of Alzheimer's disease : JAD. vol 74. issue 2. 2021-05-13. PMID:32065791. |
sleep-wake cycle in alzheimer's disease is associated with tau pathology and orexin dysregulation. |
2021-05-13 |
2023-08-13 |
Not clear |
| Yanli Jiang, Longfei Li, Chun-Ling Dai, Ranran Zhou, Cheng-Xin Gong, Khalid Iqbal, Jin-Hua Gu, Fei Li. Effect of Peripheral Insulin Administration on Phosphorylation of Tau in the Brain. Journal of Alzheimer's disease : JAD. vol 75. issue 4. 2021-05-13. PMID:32417781. |
abnormally hyperphosphorylated tau is the major protein of neurofibrillary tangles in alzheimer's disease. |
2021-05-13 |
2023-08-13 |
Not clear |
| Erratum to: Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons. Brain : a journal of neurology. vol 144. issue 4. 2021-05-13. PMID:33437996. |
erratum to: alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons. |
2021-05-13 |
2023-08-13 |
Not clear |
| Christian Humpe. Intranasal Delivery of Collagen-Loaded Neprilysin Clears Beta-Amyloid Plaques in a Transgenic Alzheimer Mouse Model. Frontiers in aging neuroscience. vol 13. 2021-05-13. PMID:33967739. |
alzheimer's disease (ad) is pathologically characterized by extracellular beta-amyloid (aβ) plaques and intraneuronal tau tangles in the brain. |
2021-05-13 |
2023-08-13 |
mouse |
| Rik Ossenkoppele, Oskar Hansso. Towards clinical application of tau PET tracers for diagnosing dementia due to Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-05-13. PMID:33984177. |
towards clinical application of tau pet tracers for diagnosing dementia due to alzheimer's disease. |
2021-05-13 |
2023-08-13 |
Not clear |
| Rik Ossenkoppele, Oskar Hansso. Towards clinical application of tau PET tracers for diagnosing dementia due to Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-05-13. PMID:33984177. |
the recent development of several tau positron emission tomography (pet) tracers represents a major milestone for the alzheimer's disease (ad) field. |
2021-05-13 |
2023-08-13 |
Not clear |
| Ryszard Pluta, Liang Ouyang, Sławomir Januszewski, Yang Li, Stanisław J Czuczwa. Participation of Amyloid and Tau Protein in Post-Ischemic Neurodegeneration of the Hippocampus of a Nature Identical to Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 5. 2021-05-12. PMID:33671097. |
participation of amyloid and tau protein in post-ischemic neurodegeneration of the hippocampus of a nature identical to alzheimer's disease. |
2021-05-12 |
2023-08-13 |
Not clear |
| Connor M Wander, Jui-Heng Tseng, Sheng Song, Heba A Al Housseiny, Dalton S Tart, Aditi Ajit, Yen-Yu Ian Shih, Rebecca Lobrovich, Juan Song, Rick B Meeker, David J Irwin, Todd J Cohe. The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging. iScience. vol 23. issue 7. 2021-05-11. PMID:32585593. |
the microtubule-associated tau protein forms pathological inclusions that accumulate in an age-dependent manner in tauopathies including alzheimer's disease (ad). |
2021-05-11 |
2023-08-13 |
mouse |
| Allal Boutajangout, Wei Zhang, Justin Kim, Wed Ali Abdali, Frances Prelli, Thomas Wisniewsk. Passive Immunization With a Novel Monoclonal Anti-PrP Antibody TW1 in an Alzheimer's Mouse Model With Tau Pathology. Frontiers in aging neuroscience. vol 13. 2021-05-11. PMID:33716717. |
passive immunization with a novel monoclonal anti-prp antibody tw1 in an alzheimer's mouse model with tau pathology. |
2021-05-11 |
2023-08-13 |
mouse |
| Ruihua Sun, Huayuan Wang, Yingying Shi, Zhikun Sun, Haisong Jiang, Jiewen Zhan. Changes in the Morphology, Number, and Pathological Protein Levels of Plasma Exosomes May Help Diagnose Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 73. issue 3. 2021-05-10. PMID:31884461. |
recent studies have shown that exosomes contain both amyloid-β (aβ) and tau proteins and have a controversial role in the alzheimer's disease (ad) process. |
2021-05-10 |
2023-08-13 |
Not clear |
| Yanying Liu, Hongmin Wan. Modeling Sporadic Alzheimer's Disease by Efficient Direct Reprogramming of the Elderly Derived Disease Dermal Fibroblasts into Neural Stem Cells. Journal of Alzheimer's disease : JAD. vol 73. issue 3. 2021-05-10. PMID:31884463. |
alzheimer's disease (ad) is a devastating neurodegenerative disorder, neuropathologically characterized by hyperphosphorylation of tau and formation of amyloid plaques. |
2021-05-10 |
2023-08-13 |
Not clear |
| Shweta Kishor Sonawane, Subashchandrabose Chinnathamb. P301 L, an FTDP-17 Mutant, Exhibits Enhanced Glycation in vitro. Journal of Alzheimer's disease : JAD. vol 75. issue 1. 2021-05-10. PMID:32250308. |
alzheimer's disease is a non-primary tauopathy, which displays tau neuropathology of excess tangle formation and accumulation. |
2021-05-10 |
2023-08-13 |
Not clear |
| Ho Jae Lim, Jung Eun Park, Byeong C Kim, Seong-Min Choi, Min-Kyung Song, Soo Hyun Cho, Hyeon Jeong Seo, Jahae Kim, Ho-Chun Song, Kyu Yeong Choi, Jang Jae Lee, Hoo-Won Kim, Jung-Min Ha, Woo Keun Song, Sung-Gyoo Park, Jung Sup Lee, Kun Ho Le. Comparison of Two Analytical Platforms in Cerebrospinal Fluid Biomarkers for the Classification of Alzheimer's Disease Spectrum with Amyloid PET Imaging. Journal of Alzheimer's disease : JAD. vol 75. issue 3. 2021-05-10. PMID:32390627. |
cerebrospinal fluid (csf) amyloid-β1-42 (aβ1-42), total tau protein (t-tau), and phosphorylated tau (p-tau) are atn biomarkers for alzheimer's disease (ad) and reflect pathogenic changes in the brain. |
2021-05-10 |
2023-08-13 |
Not clear |
| Phuong H Nguyen, Philippe Derreumau. Structures of the intrinsically disordered Aβ, tau and α-synuclein proteins in aqueous solution from computer simulations. Biophysical chemistry. vol 264. 2021-05-10. PMID:32623047. |
the aβ and tau proteins, and the α-synuclein protein, key players in alzheimer's and parkinson's diseases, respectively are fully disordered at the monomer level. |
2021-05-10 |
2023-08-13 |
human |
| Michael G Friedrich, Amanda Skora, Sarah E Hancock, Todd W Mitchell, Paul L Else, Roger J W Truscot. Tau Is Truncated in Five Regions of the Normal Adult Human Brain. International journal of molecular sciences. vol 22. issue 7. 2021-05-10. PMID:33805376. |
the truncation of tau is thought to be important in promoting aggregation, with this feature characterising the pathology of dementias such as alzheimer disease. |
2021-05-10 |
2023-08-13 |
human |
| Charuvaka Muvva, Natarajan Arul Murugan, Venkatesan Subramania. Assessment of Amyloid Forming Tendency of Peptide Sequences from Amyloid Beta and Tau Proteins Using Force-Field, Semi-Empirical, and Density Functional Theory Calculations. International journal of molecular sciences. vol 22. issue 6. 2021-05-10. PMID:33806726. |
in alzheimer's disease (ad), the extracellular aggregates originate from amyloid-β proteins, while the intracellular aggregates are formed from microtubule-binding tau proteins. |
2021-05-10 |
2023-08-13 |
Not clear |
| Annie G Bryant, Miwei Hu, Becky C Carlyle, Steven E Arnold, Matthew P Frosch, Sudeshna Das, Bradley T Hyman, Rachel E Bennet. Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Frontiers in neurology. vol 11. 2021-05-08. PMID:33041998. |
cerebrovascular senescence is associated with tau pathology in alzheimer's disease. |
2021-05-08 |
2023-08-13 |
human |
| Annie G Bryant, Miwei Hu, Becky C Carlyle, Steven E Arnold, Matthew P Frosch, Sudeshna Das, Bradley T Hyman, Rachel E Bennet. Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Frontiers in neurology. vol 11. 2021-05-08. PMID:33041998. |
alzheimer's disease (ad) is associated with neuropathological changes, including aggregation of tau neurofibrillary tangles (nfts) and amyloid-beta plaques. |
2021-05-08 |
2023-08-13 |
human |