| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rashmi Das, Abhishek Ankur Balmik, Subashchandrabose Chinnathamb. Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia. Journal of neuroinflammation. vol 17. issue 1. 2020-11-09. PMID:31915009. |
alzheimer's disease is associated with the accumulation of intracellular tau tangles within neurons and extracellular amyloid-β plaques in the brain parenchyma, which altogether results in synaptic loss and neurodegeneration. |
2020-11-09 |
2023-08-13 |
Not clear |
| Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. |
proteomic and genomic changes in tau protein, which are associated with alzheimer's disease after ischemia-reperfusion brain injury. |
2020-11-09 |
2023-08-13 |
Not clear |
| Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. |
recent evidence suggests that transient ischemia of the brain with reperfusion in humans and animals is associated with the neuronal accumulation of neurotoxic molecules associated with alzheimer's disease, such as all parts of the amyloid protein precursor and modified tau protein. |
2020-11-09 |
2023-08-13 |
Not clear |
| Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. |
pathological changes in the amyloid protein precursor and tau protein at the protein and gene level due to ischemia may lead to dementia of the alzheimer's disease type after ischemic brain injury. |
2020-11-09 |
2023-08-13 |
Not clear |
| Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. |
finally we present the positive correlation between tau protein dysfunction and the development of sporadic alzheimer's disease type of neurodegeneration. |
2020-11-09 |
2023-08-13 |
Not clear |
| Jung-Lung Hsu, Kun-Ju Lin, Ing-Tsung Hsiao, Kuo-Lun Huang, Chi-Hung Liu, Hsiu-Chuan Wu, Yi-Ching Weng, Chu-Yun Huang, Chiung-Chih Chang, Tzu-Chen Yen, Makoto Higuchi, Ming-Kuei Jang, Chin-Chang Huan. The Imaging Features and Clinical Associations of a Novel Tau PET Tracer-18F-APN1607 in Alzheimer Disease. Clinical nuclear medicine. vol 45. issue 10. 2020-11-09. PMID:32701794. |
the imaging features and clinical associations of a novel tau pet tracer-18f-apn1607 in alzheimer disease. |
2020-11-09 |
2023-08-13 |
Not clear |
| Jung-Lung Hsu, Kun-Ju Lin, Ing-Tsung Hsiao, Kuo-Lun Huang, Chi-Hung Liu, Hsiu-Chuan Wu, Yi-Ching Weng, Chu-Yun Huang, Chiung-Chih Chang, Tzu-Chen Yen, Makoto Higuchi, Ming-Kuei Jang, Chin-Chang Huan. The Imaging Features and Clinical Associations of a Novel Tau PET Tracer-18F-APN1607 in Alzheimer Disease. Clinical nuclear medicine. vol 45. issue 10. 2020-11-09. PMID:32701794. |
in vivo tau pet imaging could help clarify the spatial distribution of tau deposition in alzheimer disease (ad) and aid in the differential diagnosis of tauopathies. |
2020-11-09 |
2023-08-13 |
Not clear |
| Christian Tackenberg, Luka Kulic, Roger M Nitsc. Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. PloS one. vol 15. issue 9. 2020-11-09. PMID:32966331. |
familial alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. |
2020-11-09 |
2023-08-13 |
mouse |
| Lauren K Rudenko, Horst Wallrabe, Ammasi Periasamy, Karsten H Siller, Zdenek Svindrych, Matthew E Seward, Merci N Best, George S Bloo. Intraneuronal Tau Misfolding Induced by Extracellular Amyloid-β Oligomers. Journal of Alzheimer's disease : JAD. vol 71. issue 4. 2020-11-06. PMID:31524157. |
abnormal folding and aggregation of the microtubule-associated protein, tau, is a hallmark of several neurodegenerative disorders, including alzheimer's disease (ad). |
2020-11-06 |
2023-08-13 |
mouse |
| Carol J Huseby, Claire N Hoffman, Grace L Cooper, Jean-Christophe Cocuron, Ana P Alonso, Stefani N Thomas, Austin J Yang, Jeff Kure. Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31450505. |
quantification of tau protein lysine methylation in aging and alzheimer's disease. |
2020-11-05 |
2023-08-13 |
human |
| Arnaud Charil, Sergey Shcherbinin, Sudeepti Southekal, Michael D Devous, Mark Mintun, Melissa E Murray, Bradley B Miller, Adam J Schwar. Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31476153. |
tau subtypes of alzheimer's disease determined in vivo using flortaucipir pet imaging. |
2020-11-05 |
2023-08-13 |
human |
| Eglė Jakubauskienė, Laurynas Vilys, Inga Pečiulienė, Arvydas Kanopk. The role of hypoxia on Alzheimer's disease-related APP and Tau mRNA formation. Gene. vol 766. 2020-11-05. PMID:32941952. |
the role of hypoxia on alzheimer's disease-related app and tau mrna formation. |
2020-11-05 |
2023-08-13 |
Not clear |
| Eglė Jakubauskienė, Laurynas Vilys, Inga Pečiulienė, Arvydas Kanopk. The role of hypoxia on Alzheimer's disease-related APP and Tau mRNA formation. Gene. vol 766. 2020-11-05. PMID:32941952. |
in the presented study, we have examined the influence of cellular hypoxia on mrna splice variant formation from alzheimer's disease-related tau and app genes in brain cells. |
2020-11-05 |
2023-08-13 |
Not clear |
| Ram Reddy Chandupatla, Andrew Flatley, Regina Feederle, Eva-Maria Mandelkow, Senthilvelrajan Kaniyappa. Novel antibody against low-n oligomers of tau protein promotes clearance of tau in cells via lysosomes. Alzheimer's & dementia (New York, N. Y.). vol 6. issue 1. 2020-11-05. PMID:33145390. |
tau, a natively unfolded soluble protein, forms abnormal oligomers and insoluble filaments in several neurodegenerative diseases, including alzheimer disease (ad). |
2020-11-05 |
2023-08-13 |
Not clear |
| Paola Flores-Rodríguez, Charles R Harrington, Claude M Wischik, Vanessa Ibarra-Bracamontes, Natanael Zarco, Araceli Navarrete, Alejandra Martínez-Maldonado, Parménides Guadarrama-Ortíz, Ignacio Villanueva-Fierro, Miguel Angel Ontiveros-Torres, George Perry, Alejandra D Alonso, Benjamin Floran-Garduño, José Segovia, José Luna-Muño. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study. Journal of Alzheimer's disease : JAD. vol 71. issue 2. 2020-11-04. PMID:31424392. |
in alzheimer's disease, tau protein is the major constituent of the paired helical filament, and it undergoes post-translational modifications including hyperphosphorylation and truncation. |
2020-11-04 |
2023-08-13 |
human |
| Paola Flores-Rodríguez, Charles R Harrington, Claude M Wischik, Vanessa Ibarra-Bracamontes, Natanael Zarco, Araceli Navarrete, Alejandra Martínez-Maldonado, Parménides Guadarrama-Ortíz, Ignacio Villanueva-Fierro, Miguel Angel Ontiveros-Torres, George Perry, Alejandra D Alonso, Benjamin Floran-Garduño, José Segovia, José Luna-Muño. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study. Journal of Alzheimer's disease : JAD. vol 71. issue 2. 2020-11-04. PMID:31424392. |
whether other functions of tau protein are involved in alzheimer's disease is less clear. |
2020-11-04 |
2023-08-13 |
human |
| Xinzhu Wang, Declan Williams, Iris Müller, Mackenzie Lemieux, Ramona Dukart, Isabella B L Maia, Hansen Wang, Amanda L Woerman, Gerold Schmitt-Ulm. Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins. Scientific reports. vol 9. issue 1. 2020-11-04. PMID:31700063. |
protein interactions of tau are of interest in efforts to decipher pathogenesis in alzheimer's disease, a subset of frontotemporal dementias, and other tauopathies. |
2020-11-04 |
2023-08-13 |
mouse |
| Kavita Singh, Dhananjay Yadav, Pallavi S Chauhan, Meerambika Mishra, Jun-O Ji. Novel Therapeutics for the Treatment of Alzheimer's and Parkinson's Disease. Current pharmaceutical design. vol 26. issue 7. 2020-11-03. PMID:31914906. |
in alzheimer's, β-amyloid and tau proteinopathies are prevalent, whereas a prion-like increase of α- synuclein is the characteristic trait of parkinson's disease. |
2020-11-03 |
2023-08-13 |
Not clear |
| Tariq Ahmed, Ann Van der Jeugd, Raphaëlle Caillierez, Luc Buée, David Blum, Rudi D'Hooge, Detlef Balschu. Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of Tauopathy. Frontiers in molecular neuroscience. vol 13. 2020-11-03. PMID:33132838. |
in alzheimer's disease (ad), aggregation of hyperphosphorylated tau protein is one of the neuropathological hallmarks, and tau pathology correlates better with cognitive impairments in ad patients than amyloid-β load, supporting a key role of tau-related mechanisms. |
2020-11-03 |
2023-08-13 |
mouse |
| Nabil Itzi Luna-Viramontes, B Berenice Campa-Córdoba, Miguel Ángel Ontiveros-Torres, Charles R Harrington, Ignacio Villanueva-Fierro, Parménides Guadarrama-Ortíz, Linda Garcés-Ramírez, Fidel de la Cruz, Mario Hernandes-Alejandro, Sandra Martínez-Robles, Erik González-Ballesteros, Mar Pacheco-Herrero, José Luna-Muño. PHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer's Disease. Frontiers in cellular neuroscience. vol 14. 2020-11-03. PMID:33132840. |
phf-core tau as the potential initiating event for tau pathology in alzheimer's disease. |
2020-11-03 |
2023-08-13 |
Not clear |