All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Tushar Dubey, Nalini Vijay Gorantla, Kagepura Thammaiah Chandrashekara, Subashchandrabose Chinnathamb. Photoexcited Toluidine Blue Inhibits Tau Aggregation in Alzheimer's Disease. ACS omega. vol 4. issue 20. 2020-10-01. PMID:31737841. photoexcited toluidine blue inhibits tau aggregation in alzheimer's disease. 2020-10-01 2023-08-13 Not clear
Tushar Dubey, Nalini Vijay Gorantla, Kagepura Thammaiah Chandrashekara, Subashchandrabose Chinnathamb. Photoexcited Toluidine Blue Inhibits Tau Aggregation in Alzheimer's Disease. ACS omega. vol 4. issue 20. 2020-10-01. PMID:31737841. the aggregates of microtubule-associated protein tau are considered as a major hallmark of alzheimer's disease. 2020-10-01 2023-08-13 Not clear
Jorge Baquero, Sophia Varriano, Martha Ordonez, Pawel Kuczaj, Michael R Murphy, Gamage Aruggoda, Devon Lundine, Viktoriya Morozova, Ali Elhadi Makki, Alejandra Del C Alonso, Frida E Kleima. Nuclear Tau, p53 and Pin1 Regulate PARN-Mediated Deadenylation and Gene Expression. Frontiers in molecular neuroscience. vol 12. 2020-10-01. PMID:31749682. tau's binding factor pin1, a mitotic regulator overexpressed in cancer and depleted in alzheimer's disease (ad), also plays a role in the activation of nuclear deadenylation. 2020-10-01 2023-08-13 Not clear
S Scott Sutton, Joseph Magagnoli, Tammy Cummings, James W Hardi. Association between thiopurine medication exposure and Alzheimer's disease among a cohort of patients with inflammatory bowel disease. Alzheimer's & dementia (New York, N. Y.). vol 5. 2020-10-01. PMID:31788536. ras-related c3 botulinum toxin substrate 1 (rac1), a member of the rho-gtpase family of proteins, could be an alzheimer's disease (ad) triggering co-factor due to its effect on both amyloid precursor protein (app) and tau. 2020-10-01 2023-08-13 Not clear
Baeksun Kim, Yunjung Choi, Hye-Sun Kim, Heh-In I. Methyl-CpG Binding Protein 2 in Alzheimer Dementia. International neurourology journal. vol 23. issue Suppl 2. 2020-10-01. PMID:31795606. in particular, we focus on how the alteration of mecp2 expression can impact alzheimer disease through risk genes, amyloid-β and tau pathology, cell death and neurodegeneration, and cellular senescence. 2020-10-01 2023-08-13 Not clear
Baeksun Kim, Yunjung Choi, Hye-Sun Kim, Heh-In I. Methyl-CpG Binding Protein 2 in Alzheimer Dementia. International neurourology journal. vol 23. issue Suppl 2. 2020-10-01. PMID:31795606. we suggest that alzheimer disease can be adversely affected by upregulated mecp2-dependent repression of risk genes (mef2c, adam10, and pm20d1), increased tau accumulation, and neurodegeneration through neuronal cell death (excitotoxicity and apoptosis). 2020-10-01 2023-08-13 Not clear
Hugo Marcel Vanderstichele, Charlotte E Teunissen, Eugeen Vanmechele. Critical Steps to be Taken into Consideration Before Quantification of β-Amyloid and Tau Isoforms in Blood can be Implemented in a Clinical Environment. Neurology and therapy. vol 8. issue Suppl 2. 2020-10-01. PMID:31833029. there is a special focus on assay development for quantification of β-amyloid (aβ) and tau in blood for diagnostic use or for integration in clinical trials in the field of alzheimer's disease (ad). 2020-10-01 2023-08-13 Not clear
Marcello Esposito, Raffaele Dubbioso, Stefano Tozza, Rosa Iodice, Marco Aiello, Emanuele Nicolai, Carlo Cavaliere, Marco Salvatore, Lucio Santoro, Fiore Manganell. In vivo evidence of cortical amyloid deposition in the adult form of Niemann Pick type C. Heliyon. vol 5. issue 11. 2020-10-01. PMID:31844711. neurodegeneration in npc is associated to deposition of amyloid-β and abnormal tau aggregations likewise alzheimer disease (ad). 2020-10-01 2023-08-13 Not clear
Douglas Galasko, Meifang Xiao, Desheng Xu, Denis Smirnov, David P Salmon, Nele Dewit, Jeroen Vanbrabant, Dirk Jacobs, Hugo Vanderstichele, Eugeen Vanmechelen, Paul Worle. Synaptic biomarkers in CSF aid in diagnosis, correlate with cognition and predict progression in MCI and Alzheimer's disease. Alzheimer's & dementia (New York, N. Y.). vol 5. 2020-10-01. PMID:31853477. amyloid, tau, and neurodegeneration biomarkers can stage alzheimer's disease (ad). 2020-10-01 2023-08-13 Not clear
Athanasios Metaxas, Camilla Thygesen, Sanne R R Briting, Anne M Landau, Sultan Darvesh, Bente Finse. Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer's Disease Patients. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31866830. sections from the middle frontal gyrus (brodmann area 46) of autopsy-confirmed alzheimer's disease (ad) patients and non-demented subjects were examined for the prevalence of hallmark ad pathology, including amyloid-β (aβ) plaques, phosphorylated tau (ptau) tangles, neuroinflammation and synaptic loss ( 2020-10-01 2023-08-13 human
Christiana Bjorkli, Axel Sandvig, Ioanna Sandvi. Bridging the Gap Between Fluid Biomarkers for Alzheimer's Disease, Model Systems, and Patients. Frontiers in aging neuroscience. vol 12. 2020-10-01. PMID:32982716. alzheimer's disease (ad) is a debilitating neurodegenerative disease characterized by the accumulation of two proteins in fibrillar form: amyloid-β (aβ) and tau. 2020-10-01 2023-08-13 human
Troy T Roh. Caspase Cleaved Tau in Alzheimer's Disease: A Therapeutic Target Realized. International journal of neurology and neurotherapy. vol 2. issue 1. 2020-09-30. PMID:25639474. caspase cleaved tau in alzheimer's disease: a therapeutic target realized. 2020-09-30 2023-08-13 Not clear
Yong-Bo Hu, Yang Zou, Yue Huang, Yong-Fang Zhang, Guinevere F Lourenco, Sheng-Di Chen, Glenda M Halliday, Gang Wang, Ru-Jing Re. ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance. Frontiers in cellular neuroscience. vol 10. 2020-09-30. PMID:27853422. alzheimer's disease (ad) is the most prevalent form of late-life dementia in the population, characterized by amyloid plaque formation and increased tau deposition, which is modulated by rho-associated coiled-coil kinase 1 (rock1). 2020-09-30 2023-08-13 mouse
Athanasios Metaxas, Stefan J Kemp. Neurofibrillary tangles in Alzheimer's disease: elucidation of the molecular mechanism by immunohistochemistry and tau protein phospho-proteomics. Neural regeneration research. vol 11. issue 10. 2020-09-30. PMID:27904486. neurofibrillary tangles in alzheimer's disease: elucidation of the molecular mechanism by immunohistochemistry and tau protein phospho-proteomics. 2020-09-30 2023-08-13 Not clear
De-Yu Xia, Xin Huang, Chong-Feng Bi, Lin-Ling Mao, Li-Jun Peng, Hai-Rong Qia. PGC-1α or FNDC5 Is Involved in Modulating the Effects of Aβ Frontiers in aging neuroscience. vol 9. 2020-09-30. PMID:28377712. pgc-1α or fndc5 is involved in modulating the effects of aβ alzheimer's disease (ad) is generally defined as the aberrant production of β-amyloid protein (aβ) and hyperphosphorylated tau protein, which are deposited in β-amyloid plaques (aps) and neurofibrillary tangles (nfts), respectively. 2020-09-30 2023-08-13 mouse
Manuel Menéndez Gonzále. Mechanical Dilution of Beta-amyloid Peptide and Phosphorylated Tau Protein in Alzheimer's Disease: Too Simple to be True? Cureus. vol 9. issue 2. 2020-09-30. PMID:28382239. mechanical dilution of beta-amyloid peptide and phosphorylated tau protein in alzheimer's disease: too simple to be true? 2020-09-30 2023-08-13 Not clear
Manuel Menéndez Gonzále. Mechanical Dilution of Beta-amyloid Peptide and Phosphorylated Tau Protein in Alzheimer's Disease: Too Simple to be True? Cureus. vol 9. issue 2. 2020-09-30. PMID:28382239. the neuropathology of alzheimer's disease (ad) is characterized by the widespread accumulation of neuritic plaques and neurofibrillary tangles composed of deposits of beta-amyloid peptide (aβ) and abnormally phosphorylated tau protein (phospho-tau) respectively. 2020-09-30 2023-08-13 Not clear
Oskar Hansson, Michel J Grothe, Tor Olof Strandberg, Tomas Ohlsson, Douglas Hägerström, Jonas Jögi, Ruben Smith, Michael Schöl. Tau Pathology Distribution in Alzheimer's disease Corresponds Differentially to Cognition-Relevant Functional Brain Networks. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28408865. tau pathology distribution in alzheimer's disease corresponds differentially to cognition-relevant functional brain networks. 2020-09-30 2023-08-13 human
Oskar Hansson, Michel J Grothe, Tor Olof Strandberg, Tomas Ohlsson, Douglas Hägerström, Jonas Jögi, Ruben Smith, Michael Schöl. Tau Pathology Distribution in Alzheimer's disease Corresponds Differentially to Cognition-Relevant Functional Brain Networks. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28408865. neuropathological studies have shown that the typical neurofibrillary pathology of hyperphosphorylated tau protein in alzheimer's disease (ad) preferentially affects specific brain regions whereas others remain relatively spared. 2020-09-30 2023-08-13 human
Marvin H Berman, James P Halper, Trent W Nichols, H Jarrett, Alan Lundy, Jason H Huan. Photobiomodulation with Near Infrared Light Helmet in a Pilot, Placebo Controlled Clinical Trial in Dementia Patients Testing Memory and Cognition. Journal of neurology and neuroscience. vol 8. issue 1. 2020-09-30. PMID:28593105. the current pathophysiology of alzheimer's disease is the accumulation of neurofibrillary tangles (nfts) of hyperphosphorylated tau protein and amyloid-beta (aβ) plaques. 2020-09-30 2023-08-13 mouse