All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Taeko Kimura, Govinda Sharma, Koichi Ishiguro, Shin-Ichi Hisanag. Phospho-Tau Bar Code: Analysis of Phosphoisotypes of Tau and Its Application to Tauopathy. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:29467609. tau is also a major component of neurofibrillary tangles (nfts), a pathological hallmark in alzheimer's disease (ad). 2020-09-30 2023-08-13 Not clear
Gerhard Leinenga, Jürgen Göt. Safety and Efficacy of Scanning Ultrasound Treatment of Aged APP23 Mice. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:29467614. deposition of amyloid-β (aβ) peptide leads to amyloid plaques that together with tau deposits characterize the brains of patients with alzheimer's disease (ad). 2020-09-30 2023-08-13 mouse
Yan Zhou, Jianhua Shi, Dandan Chu, Wen Hu, Zongyu Guan, Cheng-Xin Gong, Khalid Iqbal, Fei Li. Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer's Disease. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29472853. relevance of phosphorylation and truncation of tau to the etiopathogenesis of alzheimer's disease. 2020-09-30 2023-08-13 Not clear
Yan Zhou, Jianhua Shi, Dandan Chu, Wen Hu, Zongyu Guan, Cheng-Xin Gong, Khalid Iqbal, Fei Li. Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer's Disease. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29472853. microtubule (mt) associated protein tau is abnormally hyperphosphorylated and aggregated into paired helical filaments (phfs), which manifest as neurofibrillary tangles (nfts) in the brains of individuals with alzheimer's disease (ad) and related tauopathies. 2020-09-30 2023-08-13 Not clear
Pierre De Rossi, Virginie Buggia-Prevot, Robert J Andrew, Sofia V Krause, Elizabeth Woo, Peter T Nelson, Peter Pytel, Gopal Thinakara. BIN1 localization is distinct from Tau tangles in Alzheimer's disease. Matters. vol 2017. 2020-09-30. PMID:29479533. bin1 localization is distinct from tau tangles in alzheimer's disease. 2020-09-30 2023-08-13 Not clear
Min Chen, Zhi-Yun Du, Xi Zheng, Dong-Li Li, Ren-Ping Zhou, Kun Zhan. Use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease. Neural regeneration research. vol 13. issue 4. 2020-09-30. PMID:29722330. for diagnosis of alzheimer's disease, amyloid-β and highly phosphorylated tau protein are the major biomarkers. 2020-09-30 2023-08-13 Not clear
Bettina M Foidl, Christian Humpe. Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29725295. alzheimer's disease (ad) is a progressive neurodegenerative disorder of the brain, characterized by extracellular aggregation of beta-amyloid (aβ) and hyperphosphorylation of tau causing intraneuronal neurofibrillary tangles (nfts). 2020-09-30 2023-08-13 mouse
John R Veloria, Luxi Chen, Lin Li, Gail A M Breen, Jiyong Lee, Warren J Gou. Novel cell-penetrating-amyloid peptide conjugates preferentially kill cancer cells. MedChemComm. vol 9. issue 1. 2020-09-30. PMID:30108906. here we demonstrate that two separate amyloid-forming hexapeptides, one from the microtubule associated protein tau involved in formation of paired helical filaments of alzheimer's disease, and the other an amyloid forming sequence from apolipoprotein a 2020-09-30 2023-08-13 human
Mahmoud B Maina, Laura J Bailey, Aidan J Doherty, Louise C Serpel. The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30123109. alzheimer's disease (ad) is the most common form of dementia and is distinguished from other dementias by observation of extracellular amyloid-β (aβ) plaques and intracellular neurofibrillary tangles, comprised of fibrils of aβ and tau protein, respectively. 2020-09-30 2023-08-13 human
Mahmood Rasool, Arif Malik, Sulayman Waquar, Qura Tul-Ain, Tassadaq H Jafar, Rabia Rasool, Aasia Kalsoom, Muhammad A Ghafoor, Sheikh A Sehgal, Kalamegam Gauthaman, Muhammad I Naseer, Mohammed H Al-Qahtani, Peter N Pushpara. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:30123124. alzheimer's disease (ad) is a neurodegenerative disorder characterized by dementia, excessive acetylcholinesterase (ache) activity, formation of neurotoxic amyloid plaque, and tau protein aggregation. 2020-09-30 2023-08-13 rat
Rodrigo S Chaves, Amajad I Kazi, Carolliny M Silva, Michael F Almeida, Raquel S Lima, Daniel C Carrettiero, Marilene Demasi, Merari F R Ferrar. Presence of insoluble Tau following rotenone exposure ameliorates basic pathways associated with neurodegeneration. IBRO reports. vol 1. 2020-09-30. PMID:30135926. in alzheimer's disease (ad) protein aggregates are composed of hyperphosphorylated tau and amyloid beta peptide (aβ). 2020-09-30 2023-08-13 rat
Shohreh Majd, John H T Power, Simon A Koblar, Hugh J M Grantha. The impact of tau hyperphosphorylation at Ser IBRO reports. vol 2. 2020-09-30. PMID:30135928. the impact of tau hyperphosphorylation at ser an increase in phosphorylated tau (p-tau) is associated with alzheimer's disease (ad), and brain hypoxia. 2020-09-30 2023-08-13 human
David M Smit. Could a Common Mechanism of Protein Degradation Impairment Underlie Many Neurodegenerative Diseases? Journal of experimental neuroscience. vol 12. 2020-09-30. PMID:30147359. prominent species that accumulate early and play fundamental roles in disease pathogenesis are amyloid β (aβ) and tau in alzheimer disease, α-synuclein (α-syn) in parkinson disease, and polyq-expanded huntingtin (htt) in huntington disease. 2020-09-30 2023-08-13 Not clear
Onder Albayram, Peter Angeli, Elizabeth Bernstein, Sean Baxley, Ziang Gao, Kun Ping Lu, Xiao Zhen Zho. Targeting Prion-like Cis Phosphorylated Tau Pathology in Neurodegenerative Diseases. Journal of Alzheimer's disease & Parkinsonism. vol 8. issue 3. 2020-09-30. PMID:30197831. tau is a microtubule-associated protein heavily implicated in neurodegenerative diseases collectively known as tauopathies, including alzheimer's disease and chronic traumatic encephalopathy. 2020-09-30 2023-08-13 Not clear
Kwun Chung Yu, Ping Kwan, Stanley K K Cheung, Amy Ho, Larry Bau. Effects of Resveratrol and Morin on Insoluble Tau in Tau Transgenic Mice. Translational neuroscience. vol 9. 2020-09-30. PMID:30479844. tauopathies are neurodegenerative diseases, including alzheimer's disease (ad) and frontotemporal dementia (ftd), in which tau protein aggregates within neurons. 2020-09-30 2023-08-13 mouse
Md Rashidur Rahman, Afsana Tajmim, Mohammad Ali, Mostakim Shari. Overview and Current Status of Alzheimer's Disease in Bangladesh. Journal of Alzheimer's disease reports. vol 1. issue 1. 2020-09-30. PMID:30480227. alzheimer's disease (ad) is a complex neurological disorder with economic, social, and medical burdens which is acknowledged as leading cause of dementia marked by the accumulation and aggregation of amyloid-β peptide and phosphorylated tau (p-tau) protein and concomitant dementia, neuron loss and brain atrophy. 2020-09-30 2023-08-13 Not clear
Stephen L P Lippi, Meghann L Smith, Jane M Flin. A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:30524268. a novel happ/htau mouse model of alzheimer's disease: inclusion of app with tau exacerbates behavioral deficits and zinc administration heightens tangle pathology. 2020-09-30 2023-08-13 mouse
Stephen L P Lippi, Meghann L Smith, Jane M Flin. A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:30524268. the brains of those with alzheimer's disease have amyloid and tau pathology; thus, mice modeling ad should have both markers. 2020-09-30 2023-08-13 mouse
Zeba Mueed, Pallavi Tandon, Sanjeev Kumar Maurya, Ravi Deval, Mohammad A Kamal, Nitesh Kumar Podda. Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer's Development. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30686983. tau and mtor: the hotspots for multifarious diseases in alzheimer's development. 2020-09-30 2023-08-13 Not clear
Zeba Mueed, Pallavi Tandon, Sanjeev Kumar Maurya, Ravi Deval, Mohammad A Kamal, Nitesh Kumar Podda. Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer's Development. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30686983. the hyperphosphorylation of tau protein and the overexpression of mtor are considered to be the driving force behind aβ plaques and neurofibrillay tangles (nft's), hallmarks of alzheimer's disease (ad). 2020-09-30 2023-08-13 Not clear