| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhong-Hao Zhang, Chen Chen, Qiu-Yan Wu, Rui Zheng, Yao Chen, Qiong Liu, Jia-Zuan Ni, Guo-Li Son. Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 17. issue 10. 2019-11-20. PMID:27689994. |
olfactory dysfunction is an early and common symptom in alzheimer's disease (ad) and is reported to be related to several pathologic changes, including the deposition of aβ and hyperphosphorylated tau protein as well as synaptic impairment. |
2019-11-20 |
2023-08-13 |
mouse |
| Brittany N Dugger, Charisse M Whiteside, Chera L Maarouf, Douglas G Walker, Thomas G Beach, Lucia I Sue, Angelica Garcia, Travis Dunckley, Bessie Meechoovet, Eric M Reiman, Alex E Rohe. The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 54. issue 3. 2019-11-20. PMID:27716678. |
the presence of select tau species in human peripheral tissues and their relation to alzheimer's disease. |
2019-11-20 |
2023-08-13 |
human |
| Bei Zhang, Qiongqiong Li, Xingkun Chu, Suya Sun, Shengdi Che. Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3β phosphorylation in a tau transgenic Translational neurodegeneration. vol 5. 2019-11-20. PMID:27933142. |
salidroside reduces tau hyperphosphorylation via up-regulating gsk-3β phosphorylation in a tau transgenic alzheimer's disease (ad) is an age-related and progressive neurodegenerative disease that causes substantial public health care burdens. |
2019-11-20 |
2023-08-13 |
Not clear |
| Gérard N Bischof, Frank Jessen, Klaus Fliessbach, Julian Dronse, Jochen Hammes, Bernd Neumaier, Oezguer Onur, Gereon R Fink, Juraj Kukolja, Alexander Drzezga, Thilo van Eimere. Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease. Annals of clinical and translational neurology. vol 3. issue 12. 2019-11-20. PMID:28097205. |
impact of tau and amyloid burden on glucose metabolism in alzheimer's disease. |
2019-11-20 |
2023-08-13 |
Not clear |
| Tingting Xiao, Weiwei Zhang, Bin Jiao, Chu-Zheng Pan, Xixi Liu, Lu She. The role of exosomes in the pathogenesis of Alzheimer' disease. Translational neurodegeneration. vol 6. 2019-11-20. PMID:28184302. |
accumulating evidence has demonstrated that exosomes are associated with amyloid precursor (app) and tau proteins and play a controversial role in alzheimer's disease process. |
2019-11-20 |
2023-08-13 |
Not clear |
| Urmi Sengupta, Erik Portelius, Oskar Hansson, Kathleen Farmer, Diana Castillo-Carranza, Randall Woltjer, Henrik Zetterberg, Douglas Galasko, Kaj Blennow, Rakez Kaye. Tau oligomers in cerebrospinal fluid in Alzheimer's disease. Annals of clinical and translational neurology. vol 4. issue 4. 2019-11-20. PMID:28382304. |
tau oligomers in cerebrospinal fluid in alzheimer's disease. |
2019-11-20 |
2023-08-13 |
Not clear |
| Urmi Sengupta, Erik Portelius, Oskar Hansson, Kathleen Farmer, Diana Castillo-Carranza, Randall Woltjer, Henrik Zetterberg, Douglas Galasko, Kaj Blennow, Rakez Kaye. Tau oligomers in cerebrospinal fluid in Alzheimer's disease. Annals of clinical and translational neurology. vol 4. issue 4. 2019-11-20. PMID:28382304. |
with an increasing incidence of alzheimer's disease (ad) and neurodegenerative tauopathies, there is an urgent need to develop reliable biomarkers for the diagnosis and monitoring of the disease, such as the recently discovered toxic tau oligomers. |
2019-11-20 |
2023-08-13 |
Not clear |
| Khushbu K Modi, Arundhati Jana, Supurna Ghosh, Richard Watson, Kalipada Paha. Correction: A Physically-Modified Saline Suppresses Neuronal Apoptosis, Attenuates Tau Phosphorylation and Protects Memory in an Animal Model of Alzheimer's Disease. PloS one. vol 12. issue 6. 2019-11-20. PMID:28654697. |
correction: a physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of alzheimer's disease. |
2019-11-20 |
2023-08-13 |
Not clear |
| Alessia Galasso, Charles S Cameron, Bruno G Frenguelli, Kevin G Moffa. An AMPK-dependent regulatory pathway in tau-mediated toxicity. Biology open. vol 6. issue 10. 2019-11-20. PMID:28808138. |
alongside its metabolic functions, it is also known to be activated in alzheimer's brains, phosphorylate tau, and be a critical autophagy activator. |
2019-11-20 |
2023-08-13 |
Not clear |
| Fulvio Florenzano, Corsetti Veronica, Gabriele Ciasca, Maria Teresa Ciotti, Anna Pittaluga, Gunedalina Olivero, Marco Feligioni, Filomena Iannuzzi, Valentina Latina, Michele Francesco Maria Sciacca, Alessandro Sinopoli, Danilo Milardi, Giuseppe Pappalardo, De Spirito Marco, Massimiliano Papi, Anna Atlante, Antonella Bobba, Antonella Borreca, Pietro Calissano, Giuseppina Amador. Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies. Oncotarget. vol 8. issue 39. 2019-11-20. PMID:29029390. |
extracellular truncated tau causes early presynaptic dysfunction associated with alzheimer's disease and other tauopathies. |
2019-11-20 |
2023-08-13 |
Not clear |
| Yuan Zhang, Jianghao Zhao, Mingkang Yin, Yujie Cai, Shengyuan Liu, Yan Wang, Xingliang Zhang, Hao Cao, Ting Chen, Pengru Huang, Hui Mai, Zhou Liu, Hua Tao, Bin Zhao, Lili Cu. The influence of two functional genetic variants of GRK5 on tau phosphorylation and their association with Alzheimer's disease risk. Oncotarget. vol 8. issue 42. 2019-11-20. PMID:29069820. |
the influence of two functional genetic variants of grk5 on tau phosphorylation and their association with alzheimer's disease risk. |
2019-11-20 |
2023-08-13 |
mouse |
| Yuan Zhang, Jianghao Zhao, Mingkang Yin, Yujie Cai, Shengyuan Liu, Yan Wang, Xingliang Zhang, Hao Cao, Ting Chen, Pengru Huang, Hui Mai, Zhou Liu, Hua Tao, Bin Zhao, Lili Cu. The influence of two functional genetic variants of GRK5 on tau phosphorylation and their association with Alzheimer's disease risk. Oncotarget. vol 8. issue 42. 2019-11-20. PMID:29069820. |
we confirmed that grk5 translocates from the cellular membrane to the cytosol in the hippocampus of alzheimer's disease mice and that grk5 deficiency promotes tau hyperphosphorylation, a hallmark of alzheimer's disease pathology. |
2019-11-20 |
2023-08-13 |
mouse |
| Yuan Zhang, Jianghao Zhao, Mingkang Yin, Yujie Cai, Shengyuan Liu, Yan Wang, Xingliang Zhang, Hao Cao, Ting Chen, Pengru Huang, Hui Mai, Zhou Liu, Hua Tao, Bin Zhao, Lili Cu. The influence of two functional genetic variants of GRK5 on tau phosphorylation and their association with Alzheimer's disease risk. Oncotarget. vol 8. issue 42. 2019-11-20. PMID:29069820. |
our findings suggest that the grk5-gln41leu mutant may resist tau hyperphosphorylation by promoting grk5 membrane stability and, in effect, may contribute to lower alzheimer's disease risk. |
2019-11-20 |
2023-08-13 |
mouse |
| Andrea C Klaver, Mary P Coffey, David A Bennett, David A Loeffle. Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer's disease subjects: an exploratory study. Translational neurodegeneration. vol 6. 2019-11-20. PMID:29204273. |
specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and alzheimer's disease subjects: an exploratory study. |
2019-11-20 |
2023-08-13 |
mouse |
| Andrea C Klaver, Mary P Coffey, David A Bennett, David A Loeffle. Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer's disease subjects: an exploratory study. Translational neurodegeneration. vol 6. 2019-11-20. PMID:29204273. |
tau vaccination and administration of anti-tau antibodies can prevent pathology and cognitive impairment in transgenic mouse models of tauopathy, suggesting that therapies which increase anti-tau antibodies might slow the development and/or progression of alzheimer's disease (ad). |
2019-11-20 |
2023-08-13 |
mouse |
| S Tomaszewski, S Gauthier, A Wimo, P Rosa-Net. Combination Therapy of Anti-Tau and Anti-Amyloid Drugs for Disease Modification in Early-stage Alzheimer's Disease: Socio-economic Considerations Modeled on Treatments for Tuberculosis, HIV/AIDS and Breast Cancer. The journal of prevention of Alzheimer's disease. vol 3. issue 3. 2019-11-20. PMID:29205255. |
patients with alzheimer's disease (ad) are known to have characteristic pathology, including senile plaques with amyloid beta-protein aggregates and neurofibrillary tangles with assembled tau proteins, which start in the hippocampus and spread to neighboring areas. |
2019-11-20 |
2023-08-13 |
Not clear |
| T J Littlejohns, K Kos, W E Henley, E Kuźma, D J Llewelly. Vitamin D and Dementia. The journal of prevention of Alzheimer's disease. vol 3. issue 1. 2019-11-20. PMID:29214280. |
studies have found that vitamin d is implicated in procognitive and neuroprotective functions, including the reduction of alzheimer's disease hallmarks such as amyloid beta and phosphorylated tau. |
2019-11-20 |
2023-08-13 |
human |
| Jonathan Orf, Scot Walke. BACE Inhibitors and Tau Protein Targeting Drugs in Prevention of Alzheimer's Disease. Hospital pharmacy. vol 52. issue 11. 2019-11-20. PMID:29276252. |
bace inhibitors and tau protein targeting drugs in prevention of alzheimer's disease. |
2019-11-20 |
2023-08-13 |
Not clear |
| Henrietta Wellington, Ross W Paterson, Aida Suárez-González, Teresa Poole, Chris Frost, Ulrika Sjöbom, Catherine F Slattery, Nadia K Magdalinou, Manja Lehmann, Eric Portelius, Nick C Fox, Kaj Blennow, Henrik Zetterberg, Jonathan M Schot. CSF neurogranin or tau distinguish typical and atypical Alzheimer disease. Annals of clinical and translational neurology. vol 5. issue 2. 2019-11-20. PMID:29468177. |
csf neurogranin or tau distinguish typical and atypical alzheimer disease. |
2019-11-20 |
2023-08-13 |
Not clear |
| Meng-Hui Dai, Hui Zheng, Ling-Dan Zeng, Yan Zhan. The genes associated with early-onset Alzheimer's disease. Oncotarget. vol 9. issue 19. 2019-11-20. PMID:29599933. |
alzheimer's disease (ad) is a progressive neurodegenerative disorder that accounts for the most cases of dementia, which is characterized by the deposition of dense plaques of amyloid beta (aβ) plaques and neurofibrillary tangles consisting of hyperphosphorylated tau. |
2019-11-20 |
2023-08-13 |
Not clear |