All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Krystal Herline, Eleanor Drummond, Thomas Wisniewsk. Recent advancements toward therapeutic vaccines against Alzheimer's disease. Expert review of vaccines. vol 17. issue 8. 2019-01-18. PMID:30005578. alzheimer's disease (ad) is a devastating neurodegenerative disease characterized by protein aggregates of amyloid β (aβ) and tau. 2019-01-18 2023-08-13 Not clear
Andrew Arner, Edward Rockenstein, Michael Mante, Jazmin Florio, Deborah Masliah, Bahar Salehi, Anthony Adame, Cassia Overk, Eliezer Masliah, Robert A Rissma. Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau. Journal of Alzheimer's disease : JAD. vol 61. issue 3. 2019-01-17. PMID:29332037. alzheimer's disease (ad) is the most common tauopathy, characterized by progressive accumulation of amyloid-β (aβ) and hyperphosphorylated tau. 2019-01-17 2023-08-13 mouse
David Brici, Jürgen Götz, Rebecca M Nisbe. A Novel Antibody Targeting Tau Phosphorylated at Serine 235 Detects Neurofibrillary Tangles. Journal of Alzheimer's disease : JAD. vol 61. issue 3. 2019-01-17. PMID:29332046. alzheimer's disease is characterized by two main pathological hallmarks in the human brain: the extracellular deposition of amyloid-β as plaques and the intracellular accumulation of the hyperphosphorylated protein tau as neurofibrillary tangles (nfts). 2019-01-17 2023-08-13 human
Bartosz Nizynski, Hanna Nieznanska, Robert Dec, Solomiia Boyko, Wojciech Dzwolak, Krzysztof Nieznansk. Amyloidogenic cross-seeding of Tau protein: Transient emergence of structural variants of fibrils. PloS one. vol 13. issue 7. 2019-01-17. PMID:30024984. amyloid aggregates of tau protein have been implicated in etiology of many neurodegenerative disorders including alzheimer's disease (ad). 2019-01-17 2023-08-13 human
Siddhartha Mondragón-Rodríguez, Anahí Salas-Gallardo, Perla González-Pereyra, Martín Macías, Benito Ordaz, Fernando Peña-Ortega, Azucena Aguilar-Vázquez, Erika Orta-Salazar, Sofía Díaz-Cintra, George Perry, Sylvain William. Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model. The Journal of biological chemistry. vol 293. issue 22. 2019-01-16. PMID:29632073. phosphorylation of tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in alzheimer's model. 2019-01-16 2023-08-13 mouse
Siddhartha Mondragón-Rodríguez, Anahí Salas-Gallardo, Perla González-Pereyra, Martín Macías, Benito Ordaz, Fernando Peña-Ortega, Azucena Aguilar-Vázquez, Erika Orta-Salazar, Sofía Díaz-Cintra, George Perry, Sylvain William. Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model. The Journal of biological chemistry. vol 293. issue 22. 2019-01-16. PMID:29632073. tau hyperphosphorylation at several sites, including those close to the microtubule domain region (mdr), is considered a key pathological event in the development of alzheimer's disease (ad). 2019-01-16 2023-08-13 mouse
Catherine M Roe, Ganesh M Babulal, Shruti Mishra, Brian A Gordon, Sarah H Stout, Brian R Ott, David B Carr, Beau M Ances, John C Morris, Tammie L S Benzinge. Tau and Amyloid Positron Emission Tomography Imaging Predict Driving Performance Among Older Adults with and without Preclinical Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 61. issue 2. 2019-01-15. PMID:29171997. tau and amyloid positron emission tomography imaging predict driving performance among older adults with and without preclinical alzheimer's disease. 2019-01-15 2023-08-13 human
Nadeeja Wijesekara, Rafaella Araujo Gonçalves, Rosemary Ahrens, Fernanda G De Felice, Paul E Frase. Tau ablation in mice leads to pancreatic β cell dysfunction and glucose intolerance. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 32. issue 6. 2019-01-15. PMID:29401605. abnormally phosphorylated tau aggregates assemble into neurofibrillary tangles linked to alzheimer's disease pathology and has also been found in islets of patients with type 2 diabetes. 2019-01-15 2023-08-13 mouse
Yannis Gerakis, Claudio Het. Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease. The FEBS journal. vol 285. issue 6. 2019-01-14. PMID:29148236. alzheimer's disease (ad) is a progressive neurodegenerative disease characterized by synaptic dysfunction and accumulation of abnormal aggregates formed by amyloid-β peptides or phosphorylated tau proteins. 2019-01-14 2023-08-13 Not clear
Samuele Lisi, Emmanuelle Fiore, Simona Scarano, Emanuela Pascale, Yannik Boehman, Frederic Ducongé, Sabine Chierici, Maria Minunni, Eric Peyrin, Corinne Ravele. Non-SELEX isolation of DNA aptamers for the homogeneous-phase fluorescence anisotropy sensing of tau Proteins. Analytica chimica acta. vol 1038. 2019-01-14. PMID:30278900. herein, we report for the first time the isolation of dna aptamers directed against the whole tau protein, an important alzheimer's disease (ad) biomarker. 2019-01-14 2023-08-13 Not clear
Xinghua Liu, Kuan Zeng, Mengzhu Li, Qun Wang, Rong Liu, Bin Zhang, Jian-Zhi Wang, Xiji Shu, Xiaochuan Wan. Expression of P301L-hTau in mouse MEC induces hippocampus-dependent memory deficit. Scientific reports. vol 7. issue 1. 2019-01-11. PMID:28634382. intracellular accumulation of abnormally phosphorylated tau in different types of neurons is a pathological characteristic of alzheimer's disease (ad). 2019-01-11 2023-08-13 mouse
Chao Song, Pan Deng, Long Qu. Rapid multiplexed detection of beta-amyloid and total-tau as biomarkers for Alzheimer's disease in cerebrospinal fluid. Nanomedicine : nanotechnology, biology, and medicine. vol 14. issue 6. 2019-01-11. PMID:29857195. this paper reports the multiplexed monitoring of two promising biomarkers, beta-amyloid (aβ42) and total tau (t-tau), in both buffer and cerebrospinal fluid (csf) for alzheimer's disease (ad) using label-free optical nanosensors. 2019-01-11 2023-08-13 Not clear
Yingjia Yao, Yameng Wang, Liang Kong, Yuqing Chen, Jingxian Yan. Osthole decreases tau protein phosphorylation via PI3K/AKT/GSK-3β signaling pathway in Alzheimer's disease. Life sciences. vol 217. 2019-01-11. PMID:30471283. osthole decreases tau protein phosphorylation via pi3k/akt/gsk-3β signaling pathway in alzheimer's disease. 2019-01-11 2023-08-13 Not clear
Murat Çakır, Suat Tekin, Züleyha Doğanyiğit, Yavuz Erden, Merve Soytürk, Yılmaz Çiğremiş, Süleyman Sanda. Cannabinoid type 2 receptor agonist JWH-133, attenuates Okadaic acid induced spatial memory impairment and neurodegeneration in rats. Life sciences. vol 217. 2019-01-11. PMID:30500552. we aimed to determine the possible effect of cb2 agonist jwh-133 in okadaic acid (oka)-induced neurodegeneration model mimicking alzheimer's disease (ad) through tau pathology. 2019-01-11 2023-08-13 rat
Jinhai Duan, Kristen A Marcellus, Xike Qin, Yunling Wang, Hemant K Paude. Cystatin C promotes tau protein phosphorylation and causes microtubule instability by inhibiting intracellular turnover of GSK3β in neurons. Molecular and cellular neurosciences. vol 89. 2019-01-10. PMID:29577984. in alzheimer's disease (ad) tau protein hyperphosphorylation causes neurofibrillary tangle formation, microtubule instability and neurodegeneration. 2019-01-10 2023-08-13 mouse
Mario Merlini, Tunahan Kirabali, Luka Kulic, Roger M Nitsch, Maria Teresa Ferrett. Extravascular CD3+ T Cells in Brains of Alzheimer Disease Patients Correlate with Tau but Not with Amyloid Pathology: An Immunohistochemical Study. Neuro-degenerative diseases. vol 18. issue 1. 2019-01-09. PMID:29402847. extravascular cd3+ t cells in brains of alzheimer disease patients correlate with tau but not with amyloid pathology: an immunohistochemical study. 2019-01-09 2023-08-13 Not clear
Andrée-Ann Baril, Julie Carrier, Alexandre Lafrenière, Simon Warby, Judes Poirier, Ricardo S Osorio, Najib Ayas, Marie-Pierre Dubé, Dominique Petit, Nadia Gosseli. Biomarkers of dementia in obstructive sleep apnea. Sleep medicine reviews. vol 42. 2019-01-07. PMID:30241998. many fluid biomarkers linked to alzheimer's disease and vascular dementia show abnormal levels in individuals with obstructive sleep apnea, suggesting that these conditions share common underlying mechanisms, including amyloid and tau protein neuropathology, inflammation, oxidative stress, and metabolic disturbances. 2019-01-07 2023-08-13 Not clear
Seulgi Shin, Sungsu Lim, Hyeanjeong Jeong, Li Ting Kwan, Yun Kyung Ki. Visualization of Tau⁻Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique. International journal of molecular sciences. vol 19. issue 10. 2019-01-07. PMID:30274285. due to the implication of tau aggregation in neurodegenerative disorders, including alzheimer's disease, great efforts have been made to identify the tau aggregation process. 2019-01-07 2023-08-13 Not clear
Koorosh Shahpasand, Alireza Sepehri Shamloo, Seyed Massood Nabavi, Kun Ping Lu, Xiao Zhen Zho. "Tau immunotherapy: Hopes and hindrances". Human vaccines & immunotherapeutics. vol 14. issue 2. 2019-01-04. PMID:29049003. alzheimer's disease (ad) is a progressive neurological disorder having two major pathological hallmarks: the extracellular senile plaques and intracellular neurofibrillary tangles composed of amyloid beta protein and hyperphosphorylated tau respectively. 2019-01-04 2023-08-13 mouse
Ayesha Khan, Anne Corbett, Clive Ballar. Emerging amyloid and tau targeting treatments for Alzheimer's disease. Expert review of neurotherapeutics. vol 17. issue 7. 2019-01-03. PMID:28490214. emerging amyloid and tau targeting treatments for alzheimer's disease. 2019-01-03 2023-08-13 Not clear