| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Catherine M Roe, Ganesh M Babulal, Shruti Mishra, Brian A Gordon, Sarah H Stout, Brian R Ott, David B Carr, Beau M Ances, John C Morris, Tammie L S Benzinge. Tau and Amyloid Positron Emission Tomography Imaging Predict Driving Performance Among Older Adults with and without Preclinical Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 61. issue 2. 2019-01-15. PMID:29171997. |
tau and amyloid positron emission tomography imaging predict driving performance among older adults with and without preclinical alzheimer's disease. |
2019-01-15 |
2023-08-13 |
human |
| Nadeeja Wijesekara, Rafaella Araujo Gonçalves, Rosemary Ahrens, Fernanda G De Felice, Paul E Frase. Tau ablation in mice leads to pancreatic β cell dysfunction and glucose intolerance. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 32. issue 6. 2019-01-15. PMID:29401605. |
abnormally phosphorylated tau aggregates assemble into neurofibrillary tangles linked to alzheimer's disease pathology and has also been found in islets of patients with type 2 diabetes. |
2019-01-15 |
2023-08-13 |
mouse |
| Yannis Gerakis, Claudio Het. Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease. The FEBS journal. vol 285. issue 6. 2019-01-14. PMID:29148236. |
alzheimer's disease (ad) is a progressive neurodegenerative disease characterized by synaptic dysfunction and accumulation of abnormal aggregates formed by amyloid-β peptides or phosphorylated tau proteins. |
2019-01-14 |
2023-08-13 |
Not clear |
| Samuele Lisi, Emmanuelle Fiore, Simona Scarano, Emanuela Pascale, Yannik Boehman, Frederic Ducongé, Sabine Chierici, Maria Minunni, Eric Peyrin, Corinne Ravele. Non-SELEX isolation of DNA aptamers for the homogeneous-phase fluorescence anisotropy sensing of tau Proteins. Analytica chimica acta. vol 1038. 2019-01-14. PMID:30278900. |
herein, we report for the first time the isolation of dna aptamers directed against the whole tau protein, an important alzheimer's disease (ad) biomarker. |
2019-01-14 |
2023-08-13 |
Not clear |
| Xinghua Liu, Kuan Zeng, Mengzhu Li, Qun Wang, Rong Liu, Bin Zhang, Jian-Zhi Wang, Xiji Shu, Xiaochuan Wan. Expression of P301L-hTau in mouse MEC induces hippocampus-dependent memory deficit. Scientific reports. vol 7. issue 1. 2019-01-11. PMID:28634382. |
intracellular accumulation of abnormally phosphorylated tau in different types of neurons is a pathological characteristic of alzheimer's disease (ad). |
2019-01-11 |
2023-08-13 |
mouse |
| Chao Song, Pan Deng, Long Qu. Rapid multiplexed detection of beta-amyloid and total-tau as biomarkers for Alzheimer's disease in cerebrospinal fluid. Nanomedicine : nanotechnology, biology, and medicine. vol 14. issue 6. 2019-01-11. PMID:29857195. |
this paper reports the multiplexed monitoring of two promising biomarkers, beta-amyloid (aβ42) and total tau (t-tau), in both buffer and cerebrospinal fluid (csf) for alzheimer's disease (ad) using label-free optical nanosensors. |
2019-01-11 |
2023-08-13 |
Not clear |
| Yingjia Yao, Yameng Wang, Liang Kong, Yuqing Chen, Jingxian Yan. Osthole decreases tau protein phosphorylation via PI3K/AKT/GSK-3β signaling pathway in Alzheimer's disease. Life sciences. vol 217. 2019-01-11. PMID:30471283. |
osthole decreases tau protein phosphorylation via pi3k/akt/gsk-3β signaling pathway in alzheimer's disease. |
2019-01-11 |
2023-08-13 |
Not clear |
| Murat Çakır, Suat Tekin, Züleyha Doğanyiğit, Yavuz Erden, Merve Soytürk, Yılmaz Çiğremiş, Süleyman Sanda. Cannabinoid type 2 receptor agonist JWH-133, attenuates Okadaic acid induced spatial memory impairment and neurodegeneration in rats. Life sciences. vol 217. 2019-01-11. PMID:30500552. |
we aimed to determine the possible effect of cb2 agonist jwh-133 in okadaic acid (oka)-induced neurodegeneration model mimicking alzheimer's disease (ad) through tau pathology. |
2019-01-11 |
2023-08-13 |
rat |
| Jinhai Duan, Kristen A Marcellus, Xike Qin, Yunling Wang, Hemant K Paude. Cystatin C promotes tau protein phosphorylation and causes microtubule instability by inhibiting intracellular turnover of GSK3β in neurons. Molecular and cellular neurosciences. vol 89. 2019-01-10. PMID:29577984. |
in alzheimer's disease (ad) tau protein hyperphosphorylation causes neurofibrillary tangle formation, microtubule instability and neurodegeneration. |
2019-01-10 |
2023-08-13 |
mouse |
| Mario Merlini, Tunahan Kirabali, Luka Kulic, Roger M Nitsch, Maria Teresa Ferrett. Extravascular CD3+ T Cells in Brains of Alzheimer Disease Patients Correlate with Tau but Not with Amyloid Pathology: An Immunohistochemical Study. Neuro-degenerative diseases. vol 18. issue 1. 2019-01-09. PMID:29402847. |
extravascular cd3+ t cells in brains of alzheimer disease patients correlate with tau but not with amyloid pathology: an immunohistochemical study. |
2019-01-09 |
2023-08-13 |
Not clear |
| Andrée-Ann Baril, Julie Carrier, Alexandre Lafrenière, Simon Warby, Judes Poirier, Ricardo S Osorio, Najib Ayas, Marie-Pierre Dubé, Dominique Petit, Nadia Gosseli. Biomarkers of dementia in obstructive sleep apnea. Sleep medicine reviews. vol 42. 2019-01-07. PMID:30241998. |
many fluid biomarkers linked to alzheimer's disease and vascular dementia show abnormal levels in individuals with obstructive sleep apnea, suggesting that these conditions share common underlying mechanisms, including amyloid and tau protein neuropathology, inflammation, oxidative stress, and metabolic disturbances. |
2019-01-07 |
2023-08-13 |
Not clear |
| Seulgi Shin, Sungsu Lim, Hyeanjeong Jeong, Li Ting Kwan, Yun Kyung Ki. Visualization of Tau⁻Tubulin Interaction in a Living Cell Using Bifluorescence Complementation Technique. International journal of molecular sciences. vol 19. issue 10. 2019-01-07. PMID:30274285. |
due to the implication of tau aggregation in neurodegenerative disorders, including alzheimer's disease, great efforts have been made to identify the tau aggregation process. |
2019-01-07 |
2023-08-13 |
Not clear |
| Koorosh Shahpasand, Alireza Sepehri Shamloo, Seyed Massood Nabavi, Kun Ping Lu, Xiao Zhen Zho. "Tau immunotherapy: Hopes and hindrances". Human vaccines & immunotherapeutics. vol 14. issue 2. 2019-01-04. PMID:29049003. |
alzheimer's disease (ad) is a progressive neurological disorder having two major pathological hallmarks: the extracellular senile plaques and intracellular neurofibrillary tangles composed of amyloid beta protein and hyperphosphorylated tau respectively. |
2019-01-04 |
2023-08-13 |
mouse |
| Ayesha Khan, Anne Corbett, Clive Ballar. Emerging amyloid and tau targeting treatments for Alzheimer's disease. Expert review of neurotherapeutics. vol 17. issue 7. 2019-01-03. PMID:28490214. |
emerging amyloid and tau targeting treatments for alzheimer's disease. |
2019-01-03 |
2023-08-13 |
Not clear |
| Ramesh Kandimalla, Maria Manczak, Xiangling Yin, Rui Wang, P Hemachandra Redd. Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease. Human molecular genetics. vol 27. issue 1. 2019-01-02. PMID:29040533. |
hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of alzheimer's disease. |
2019-01-02 |
2023-08-13 |
mouse |
| Julian H Birnbaum, Debora Wanner, Anton F Gietl, Antje Saake, Thomas M Kündig, Christoph Hock, Roger M Nitsch, Christian Tackenber. Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients. Stem cell research. vol 27. 2019-01-02. PMID:29414602. |
oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in ipsc-derived neurons from sporadic alzheimer's disease patients. |
2019-01-02 |
2023-08-13 |
human |
| María José Pérez, Katiana Vergara-Pulgar, Claudia Jara, Fabian Cabezas-Opazo, Rodrigo A Quintanill. Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer's Disease. Molecular neurobiology. vol 55. issue 2. 2019-01-01. PMID:28084594. |
caspase-cleaved tau impairs mitochondrial dynamics in alzheimer's disease. |
2019-01-01 |
2023-08-13 |
mouse |
| María José Pérez, Katiana Vergara-Pulgar, Claudia Jara, Fabian Cabezas-Opazo, Rodrigo A Quintanill. Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer's Disease. Molecular neurobiology. vol 55. issue 2. 2019-01-01. PMID:28084594. |
alzheimer's disease (ad) is characterized by the presence of aggregates of tau protein. |
2019-01-01 |
2023-08-13 |
mouse |
| Fang Fang, Wanlin Yang, Jazmin B Florio, Edward Rockenstein, Brian Spencer, Xavier M Orain, Stephanie X Dong, Huayan Li, Xuqiao Chen, Kijung Sung, Robert A Rissman, Eliezer Masliah, Jianqing Ding, Chengbiao W. Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease. Scientific reports. vol 7. issue 1. 2018-12-31. PMID:28634349. |
recent studies have demonstrated that hyperphosphorylation of tau protein plays a role in neuronal toxicities of α-synuclein (asyn) in neurodegenerative disease such as familial alzheimer's disease (ad), dementia with lewy bodies (dlb) and parkinson's disease. |
2018-12-31 |
2023-08-13 |
mouse |
| Susanne Wegmann, Bahareh Eftekharzadeh, Katharina Tepper, Katarzyna M Zoltowska, Rachel E Bennett, Simon Dujardin, Pawel R Laskowski, Danny MacKenzie, Tarun Kamath, Caitlin Commins, Charles Vanderburg, Allyson D Roe, Zhanyun Fan, Amandine M Molliex, Amayra Hernandez-Vega, Daniel Muller, Anthony A Hyman, Eckhard Mandelkow, J Paul Taylor, Bradley T Hyma. Tau protein liquid-liquid phase separation can initiate tau aggregation. The EMBO journal. vol 37. issue 7. 2018-12-28. PMID:29472250. |
the transition between soluble intrinsically disordered tau protein and aggregated tau in neurofibrillary tangles in alzheimer's disease is unknown. |
2018-12-28 |
2023-08-13 |
human |