All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Bess Frost, Martin Hemberg, Jada Lewis, Mel B Fean. Tau promotes neurodegeneration through global chromatin relaxation. Nature neuroscience. vol 17. issue 3. 2014-05-16. PMID:24464041. the microtubule-associated protein tau is involved in a number of neurodegenerative disorders, including alzheimer's disease. 2014-05-16 2023-08-12 mouse
Bess Frost, Martin Hemberg, Jada Lewis, Mel B Fean. Tau promotes neurodegeneration through global chromatin relaxation. Nature neuroscience. vol 17. issue 3. 2014-05-16. PMID:24464041. we found widespread loss of heterochromatin in tau transgenic drosophila and mice and in human alzheimer's disease. 2014-05-16 2023-08-12 mouse
Yongchang Diwu, Jinzhou Tian, Jing Sh. [Effects of Xixin decoction on enzymes related to O-GlcNAc glycosylation of tau proteins in the brain of rats with sporadic Alzheimer's disease]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 33. issue 10. 2014-05-15. PMID:24144743. [effects of xixin decoction on enzymes related to o-glcnac glycosylation of tau proteins in the brain of rats with sporadic alzheimer's disease]. 2014-05-15 2023-08-12 rat
Yongchang Diwu, Jinzhou Tian, Jing Sh. [Effects of Xixin decoction on enzymes related to O-GlcNAc glycosylation of tau proteins in the brain of rats with sporadic Alzheimer's disease]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 33. issue 10. 2014-05-15. PMID:24144743. to study the effects of xixin decoction (xxd) on o-glcnac transferase (ogt) and o-glcnac glycosidase in o-glcnac glycosylation of tau proteins in the brain of rats with sporadic alzheimer's disease (sad) and explore the possible mechanism. 2014-05-15 2023-08-12 rat
Luis F Maia, Stephan A Kaeser, Julia Reichwald, Michael Hruscha, Peter Martus, Matthias Staufenbiel, Mathias Jucke. Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein. Science translational medicine. vol 5. issue 194. 2014-05-14. PMID:23863834. altered concentrations of amyloid-β (aβ) peptide and tau protein in the cerebrospinal fluid (csf) are thought to be predictive markers for alzheimer's disease (ad). 2014-05-14 2023-08-12 mouse
Yun Li, Yahong Liu, Zhaojun Wang, Yongjun Jian. Clinical trials of amyloid-based immunotherapy for Alzheimer's disease: end of beginning or beginning of end? Expert opinion on biological therapy. vol 13. issue 11. 2014-05-12. PMID:24053611. amyloid deposit and hyperphosphorylated tau protein contribute to pathological changes seen in alzheimer's disease (ad) and imply that removal may reverse the cognitive decline. 2014-05-12 2023-08-12 Not clear
Diego Iacono, Susan M Resnick, Richard O'Brien, Alan B Zonderman, Yang An, Olga Pletnikova, Gay Rudow, Barbara Crain, Juan C Troncos. Mild cognitive impairment and asymptomatic Alzheimer disease subjects: equivalent β-amyloid and tau loads with divergent cognitive outcomes. Journal of neuropathology and experimental neurology. vol 73. issue 4. 2014-05-12. PMID:24607960. mild cognitive impairment and asymptomatic alzheimer disease subjects: equivalent β-amyloid and tau loads with divergent cognitive outcomes. 2014-05-12 2023-08-12 human
Diana L Castillo-Carranza, Urmi Sengupta, Marcos J Guerrero-Muñoz, Cristian A Lasagna-Reeves, Julia E Gerson, Gurpreet Singh, D Mark Estes, Alan D T Barrett, Kelly T Dineley, George R Jackson, Rakez Kaye. Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 12. 2014-05-08. PMID:24647946. recent findings suggest that tau oligomers, which form before neurofibrillary tangles (nfts), are the true neurotoxic tau entities in neurodegenerative tauopathies, including alzheimer's disease (ad). 2014-05-08 2023-08-12 mouse
Li-Rong Xu, Xiao-Ling Liu, Jie Chen, Yi Lian. Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization. PloS one. vol 8. issue 10. 2014-04-29. PMID:24098548. tau protein is implicated in the pathogenesis of neurodegenerative disorders such as tauopathies including alzheimer disease, and tau fibrillization is thought to be related to neuronal toxicity. 2014-04-29 2023-08-12 Not clear
Li-Rong Xu, Xiao-Ling Liu, Jie Chen, Yi Lian. Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization. PloS one. vol 8. issue 10. 2014-04-29. PMID:24098548. physiological inhibitors of tau fibrillization hold promise for developing new strategies for treatment of alzheimer disease. 2014-04-29 2023-08-12 Not clear
Li-Rong Xu, Xiao-Ling Liu, Jie Chen, Yi Lian. Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization. PloS one. vol 8. issue 10. 2014-04-29. PMID:24098548. because protein disulfide isomerase (pdi) is both an enzyme and a chaperone, and implicated in neuroprotection against alzheimer disease, we want to know whether pdi can prevent tau fibrillization. 2014-04-29 2023-08-12 Not clear
J Pozueta, R Lefort, M L Shelansk. Synaptic changes in Alzheimer's disease and its models. Neuroscience. vol 251. 2014-04-23. PMID:22687952. alzheimer's disease (ad) is a highly prevalent neurodegenerative disorder characterized by a progressive loss of cognition and the presence of two hallmark lesions, senile plaques (sp) and neurofibrillary tangles (nft), which result from the accumulation and deposition of the β-amyloid peptide (aβ) and the aggregation of hyperphosphorylated tau protein, respectively. 2014-04-23 2023-08-12 Not clear
Ana M García-Cabrero, Rosa Guerrero-López, Beatriz G Giráldez, María Llorens-Martín, Jesús Avila, José M Serratosa, Marina P Sánche. Hyperexcitability and epileptic seizures in a model of frontotemporal dementia. Neurobiology of disease. vol 58. 2014-04-23. PMID:23774255. abnormal forms of hyperphosphorylated tau accumulate in alzheimer disease and other tauopathies. 2014-04-23 2023-08-12 mouse
Un Young Yu, Byong Chul Yoo, Jung-Hyuck Ah. Regulatory B Subunits of Protein Phosphatase 2A Are Involved in Site-specific Regulation of Tau Protein Phosphorylation. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 18. issue 2. 2014-04-23. PMID:24757378. hyperphosphorylated isoforms of tau are major components of neurofibrillary tangles, which are histopathological hallmarks of alzheimer's disease. 2014-04-23 2023-08-13 Not clear
Yu-Jing Tan, Dexin Sui, Wei-Han Wang, Min-Hao Kuo, Gavin E Reid, Merlin L Bruenin. Phosphopeptide enrichment with TiO2-modified membranes and investigation of tau protein phosphorylation. Analytical chemistry. vol 85. issue 12. 2014-04-22. PMID:23638980. the combination of membrane enrichment with tandem mass spectrometry reveals seven phosphorylation sites from in vivo phosphorylated tau (p-tau) protein, which is associated with alzheimer's disease. 2014-04-22 2023-08-12 Not clear
Qing Yan Liu, Marilyn N Vera Chang, Joy X Lei, Roger Koukiekolo, Brandon Smith, Dongling Zhang, Othman Ghrib. Identification of microRNAs involved in Alzheimer's progression using a rabbit model of the disease. American journal of neurodegenerative disease. vol 3. issue 1. 2014-04-22. PMID:24754001. alzheimer's disease (ad) is the most common neurodegenerative disorder characterized by the presence of extracellular plaques of β-amyloid peptides and intracellular tangles of hyperphosphorylated tau proteins in the brain. 2014-04-22 2023-08-13 human
Toshihisa Tanaka, Daisuke Mayuyama, Masatoshi Taked. [Alzheimer disease and tau protein]. Rinsho shinkeigaku = Clinical neurology. vol 52. issue 11. 2014-04-21. PMID:23196553. [alzheimer disease and tau protein]. 2014-04-21 2023-08-12 Not clear
Toshihisa Tanaka, Daisuke Mayuyama, Masatoshi Taked. [Alzheimer disease and tau protein]. Rinsho shinkeigaku = Clinical neurology. vol 52. issue 11. 2014-04-21. PMID:23196553. to elucidate involvement of tau protein in neurodegenerative processes in alzheimer disease and related disorders, self-assembly process and degradative process of tau protein were examined. 2014-04-21 2023-08-12 Not clear
Lucilla Parnetti, Lucia Farotti, Paolo Eusebi, Davide Chiasserini, Claudia De Carlo, David Giannandrea, Nicola Salvadori, Viviana Lisetti, Nicola Tambasco, Aroldo Rossi, Nour K Majbour, Omar El-Agnaf, Paolo Calabres. Differential role of CSF alpha-synuclein species, tau, and Aβ42 in Parkinson's Disease. Frontiers in aging neuroscience. vol 6. 2014-04-18. PMID:24744728. preliminary evidences show that the combination of csf t-α-syn and classical alzheimer's disease (ad) biomarkers-β-amyloid 1-42 (aβ42), total tau (t-tau), phosphorylated tau (p-tau)-differentiate pd patients from controls, and that reduced levels of aβ42 represent a predictive factor for development of cognitive deterioration in pd. 2014-04-18 2023-08-13 Not clear
Gucci Jijuan Gu, Harald Lund, Di Wu, Andries Blokzijl, Christina Classon, Gabriel von Euler, Ulf Landegren, Dan Sunnemark, Masood Kamali-Moghadda. Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease. Neuromolecular medicine. vol 15. issue 3. 2014-04-15. PMID:23666762. role of individual mark isoforms in phosphorylation of tau at ser²⁶² in alzheimer's disease. 2014-04-15 2023-08-12 human