All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Khoren K Epremyan, Dmitry V Mamaev, Renata A Zvyagilskay. Alzheimer's Disease: Significant Benefit from the Yeast-Based Models. International journal of molecular sciences. vol 24. issue 12. 2023-06-28. PMID:37372938. alzheimer's disease (ad) is an age-related, multifaceted neurological disorder associated with accumulation of aggregated proteins (amyloid aβ and hyperphosphorylated tau), loss of synapses and neurons, and alterations in microglia. 2023-06-28 2023-08-14 Not clear
Deborah Inyang, Tasneem Saumtally, Chinelo Nonyerem Nnadi, Sharmila Devi, Po-Wah S. A Systematic Review of the Effects of Capsaicin on Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 12. 2023-06-28. PMID:37373321. alzheimer's disease (ad) is a progressive neurodegenerative disorder characterised by cognitive impairment, and amyloid-β plaques and neurofibrillary tau tangles at neuropathology. 2023-06-28 2023-08-14 rat
Fan Chen, Na Wang, Xinyan Tian, Juan Su, Yan Qin, Rongqiao He, Xiaping H. The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment. Pharmaceutics. vol 15. issue 6. 2023-06-28. PMID:37376018. formaldehyde (fa) has been found to induce major alzheimer's disease (ad)-like features including cognitive impairment, aβ deposition, and tau hyperphosphorylation, suggesting that it may play a significant role in the initiation and progression of ad. 2023-06-28 2023-08-14 Not clear
Correction to: Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration. Brain : a journal of neurology. 2023-06-27. PMID:37365902. correction to: brain-derived tau: a novel blood-based biomarker for alzheimer's disease-type neurodegeneration. 2023-06-27 2023-08-14 Not clear
Kyoka Hoshi, Mayumi Kanno, Mitsunari Abe, Takenobu Murakami, Yoshikazu Ugawa, Aya Goto, Takashi Honda, Takashi Saito, Takaomi C Saido, Yoshiki Yamaguchi, Masakazu Miyajima, Katsutoshi Furukawa, Hiroyuki Arai, Yasuhiro Hashimot. Correction: Hoshi et al. High Correlation among Brain-Derived Major Protein Levels in Cerebrospinal Fluid: Implication for Amyloid-Beta and Tau Protein Changes in Alzheimer's Disease. Metabolites. vol 13. issue 6. 2023-06-27. PMID:37367930. high correlation among brain-derived major protein levels in cerebrospinal fluid: implication for amyloid-beta and tau protein changes in alzheimer's disease. 2023-06-27 2023-08-14 Not clear
Lan Xiao, Xuyu Yang, Vinay Kumar Sharma, Daniel Abebe, Y Peng Lo. Hippocampal delivery of neurotrophic factor-α1/carboxypeptidase E gene prevents neurodegeneration, amyloidosis, memory loss in Alzheimer's Disease male mice. Molecular psychiatry. 2023-06-27. PMID:37369719. alzheimer's disease (ad) is a prevalent neurodegenerative disease characterized by tau hyperphosphorylation, aβ1-42 aggregation and cognitive dysfunction. 2023-06-27 2023-08-14 mouse
Débora E Peretti, Federica Ribaldi, Max Scheffler, Christian Chicherio, Giovanni B Frisoni, Valentina Garibott. Prognostic value of imaging-based ATN profiles in a memory clinic cohort. European journal of nuclear medicine and molecular imaging. 2023-06-26. PMID:37358619. the atn model represents a research framework used to classify subjects based on the presence or absence of alzheimer's disease (ad) pathology through biomarkers for amyloid (a), tau (t), and neurodegeneration (n). 2023-06-26 2023-08-14 human
Masihuz Zaman, Yingxue Fu, Ping-Chung Chen, Huan Sun, Shu Yang, Zhiping Wu, Zhen Wang, Suresh Poudel, Geidy E Serrano, Thomas G Beach, Ling Li, Xusheng Wang, Junmin Pen. Dissecting detergent-insoluble proteome in Alzheimer's disease by TMTc-corrected quantitative mass spectrometry. Molecular & cellular proteomics : MCP. 2023-06-25. PMID:37356496. protein aggregation of amyloid-β (aβ) peptides and tau are pathological hallmarks of alzheimer's disease (ad), which are often resistant to detergent extraction and thus enriched in the insoluble proteome. 2023-06-25 2023-08-14 human
L Iaccarino, S C Burnham, G Dell'Agnello, S A Dowsett, S Epelbau. Diagnostic Biomarkers of Amyloid and Tau Pathology in Alzheimer's Disease: An Overview of Tests for Clinical Practice in the United States and Europe. The journal of prevention of Alzheimer's disease. vol 10. issue 3. 2023-06-25. PMID:37357283. diagnostic biomarkers of amyloid and tau pathology in alzheimer's disease: an overview of tests for clinical practice in the united states and europe. 2023-06-25 2023-08-14 Not clear
L Iaccarino, S C Burnham, G Dell'Agnello, S A Dowsett, S Epelbau. Diagnostic Biomarkers of Amyloid and Tau Pathology in Alzheimer's Disease: An Overview of Tests for Clinical Practice in the United States and Europe. The journal of prevention of Alzheimer's disease. vol 10. issue 3. 2023-06-25. PMID:37357283. amyloid and tau biomarkers for alzheimer's disease are widely recognized diagnostic tools for the identification of alzheimer's disease pathology antemortem and are recommended by the most recent clinical and research guidelines. 2023-06-25 2023-08-14 Not clear
L Iaccarino, S C Burnham, G Dell'Agnello, S A Dowsett, S Epelbau. Diagnostic Biomarkers of Amyloid and Tau Pathology in Alzheimer's Disease: An Overview of Tests for Clinical Practice in the United States and Europe. The journal of prevention of Alzheimer's disease. vol 10. issue 3. 2023-06-25. PMID:37357283. all available pet amyloid and tau biomarkers demonstrate high accuracy in identifying amyloid and tau alzheimer's disease pathology, respectively, at autopsy. 2023-06-25 2023-08-14 Not clear
L Iaccarino, S C Burnham, G Dell'Agnello, S A Dowsett, S Epelbau. Diagnostic Biomarkers of Amyloid and Tau Pathology in Alzheimer's Disease: An Overview of Tests for Clinical Practice in the United States and Europe. The journal of prevention of Alzheimer's disease. vol 10. issue 3. 2023-06-25. PMID:37357283. overall, we conclude that commercially available pet, cerebrospinal fluid and plasma assays accurately identify alzheimer's disease amyloid and tau pathology. 2023-06-25 2023-08-14 Not clear
K P Ng, J Y Shen, H J Chiew, A S L Ng, N Kandiah, P Rosa-Neto, S Gauthie. White Matter Hyperintensity as a Vascular Contribution to the AT(N) Framework. The journal of prevention of Alzheimer's disease. vol 10. issue 3. 2023-06-25. PMID:37357280. the at(n) framework enables the classification of an individual within the biological alzheimer's disease (ad) continuum by pairing the cognitive stage with the biomarker status of amyloid-beta (aβ, a), tau (t) and neurodegeneration (n). 2023-06-25 2023-08-14 Not clear
Dianne Marquez Lopez, Connor J Maltby, Hannah Warming, Nullin Divecha, Mariana Vargas-Caballero, Mark J Coldwell, Katrin Deinhard. A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau. Frontiers in neuroscience. vol 17. 2023-06-22. PMID:37342467. in alzheimer's disease, tau pathology is thought to spread via a prion-like manner along connected neuronal networks. 2023-06-22 2023-08-14 Not clear
Nathalie Kyalu Ngoie Zola, Clémence Balty, Sébastien Pyr Dit Ruys, Axelle A T Vanparys, Nicolas D G Huyghe, Gaëtan Herinckx, Manuel Johanns, Emilien Boyer, Pascal Kienlen-Campard, Mark H Rider, Didier Vertommen, Bernard J Hanseeu. Specific post-translational modifications of soluble tau protein distinguishes Alzheimer's disease and primary tauopathies. Nature communications. vol 14. issue 1. 2023-06-22. PMID:37349319. specific post-translational modifications of soluble tau protein distinguishes alzheimer's disease and primary tauopathies. 2023-06-22 2023-08-14 human
Nathalie Kyalu Ngoie Zola, Clémence Balty, Sébastien Pyr Dit Ruys, Axelle A T Vanparys, Nicolas D G Huyghe, Gaëtan Herinckx, Manuel Johanns, Emilien Boyer, Pascal Kienlen-Campard, Mark H Rider, Didier Vertommen, Bernard J Hanseeu. Specific post-translational modifications of soluble tau protein distinguishes Alzheimer's disease and primary tauopathies. Nature communications. vol 14. issue 1. 2023-06-22. PMID:37349319. we therefore characterized post-translational modifications of both the aggregated and the soluble tau protein obtained from post mortem human brain tissue of patients with alzheimer's disease, cortico-basal degeneration, pick's disease, and frontotemporal lobe degeneration. 2023-06-22 2023-08-14 human
Klara Zubčić, Dina Franić, Mihaela Pravica, Patrick R Hof, Goran Šimić, Mirta Boba. Effects of heterologous human tau protein expression in yeast models of proteotoxic stress response. CNS neuroscience & therapeutics. 2023-06-21. PMID:37341072. the primary histological characteristic of alzheimer's disease is the presence of neurofibrillary tangles, which are large aggregates of tau protein. 2023-06-21 2023-08-14 human
Klara Zubčić, Dina Franić, Mihaela Pravica, Patrick R Hof, Goran Šimić, Mirta Boba. Effects of heterologous human tau protein expression in yeast models of proteotoxic stress response. CNS neuroscience & therapeutics. 2023-06-21. PMID:37341072. aging is the primary risk factor for the development of alzheimer's disease, however, the underlying causes of tau protein aggregation and toxicity are unclear. 2023-06-21 2023-08-14 human
Anastasie Mate De Gerando, Lindsay A Welikovitch, Anita Khasnavis, Caitlin Commins, Calina Glynn, Joshua E Chun, Romain Perbet, Bradley T Hyma. Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau. Acta neuropathologica. 2023-06-21. PMID:37341831. insoluble fibrillar tau, the primary constituent of neurofibrillary tangles, has traditionally been thought to be the biologically active, toxic form of tau mediating neurodegeneration in alzheimer's disease. 2023-06-21 2023-08-14 mouse
Anastasie Mate De Gerando, Lindsay A Welikovitch, Anita Khasnavis, Caitlin Commins, Calina Glynn, Joshua E Chun, Romain Perbet, Bradley T Hyma. Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau. Acta neuropathologica. 2023-06-21. PMID:37341831. we prepared sarkosyl-insoluble and hmw tau from the frontal cortex of alzheimer patients and compared their properties using a variety of biophysical and bioactivity assays. 2023-06-21 2023-08-14 mouse