| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Duke Han, Jonathan Gruhl, Laurel Beckett, Hiroko H Dodge, Nikki H Stricker, Sarah Farias, Dan Munga. Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer's Disease. Brain imaging and behavior. vol 6. issue 4. 2013-08-02. PMID:22648764. |
beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for alzheimer's disease. |
2013-08-02 |
2023-08-12 |
Not clear |
| Juneyoung Yi, David J Padalino, Lawrence S Chin, Philip Montenegro, Robert C Cant. Chronic traumatic encephalopathy. Current sports medicine reports. vol 12. issue 1. 2013-08-01. PMID:23314081. |
these finding were similar to alzheimer's disease in some ways but differed in critical areas such as a predominance of tau protein deposition over amyloid. |
2013-08-01 |
2023-08-12 |
Not clear |
| Antonino Cattaneo, Pietro Calissan. Nerve growth factor and Alzheimer's disease: new facts for an old hypothesis. Molecular neurobiology. vol 46. issue 3. 2013-07-30. PMID:22940884. |
understanding sporadic alzheimer's disease (ad) onset and progression requires an explanation of what triggers the common core of abnormal processing of the amyloid precursor protein and tau processing. |
2013-07-30 |
2023-08-12 |
mouse |
| Eva-Maria Mandelkow, Eckhard Mandelko. Biochemistry and cell biology of tau protein in neurofibrillary degeneration. Cold Spring Harbor perspectives in medicine. vol 2. issue 7. 2013-07-29. PMID:22762014. |
tau represents the subunit protein of one of the major hallmarks of alzheimer disease (ad), the neurofibrillary tangles, and is therefore of major interest as an indicator of disease mechanisms. |
2013-07-29 |
2023-08-12 |
Not clear |
| Allyson V McCormick, Jeanna M Wheeler, Chris R Guthrie, Nicole F Liachko, Brian C Kraeme. Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity. Biological psychiatry. vol 73. issue 5. 2013-07-26. PMID:23140663. |
tauopathies, including alzheimer's disease and frontotemporal dementia, are diseases characterized by the formation of pathological tau protein aggregates in the brain and progressive neurodegeneration. |
2013-07-26 |
2023-08-12 |
Not clear |
| Bethany L Veo, Leslie A Krushe. Secondary RNA structure and nucleotide specificity contribute to internal initiation mediated by the human tau 5' leader. RNA biology. vol 9. issue 11. 2013-07-25. PMID:22995835. |
overall, these results identify structural and sequence elements critical for tau ires activity and consequently, provide a novel target to regulate tau protein expression in disease states including alzheimer disease and other tauopathies. |
2013-07-25 |
2023-08-12 |
human |
| D C Lee, J Rizer, J B Hunt, M-L B Selenica, M N Gordon, D Morga. Review: experimental manipulations of microglia in mouse models of Alzheimer's pathology: activation reduces amyloid but hastens tau pathology. Neuropathology and applied neurobiology. vol 39. issue 1. 2013-07-24. PMID:23171029. |
review: experimental manipulations of microglia in mouse models of alzheimer's pathology: activation reduces amyloid but hastens tau pathology. |
2013-07-24 |
2023-08-12 |
mouse |
| Julia E Gerson, Rakez Kaye. Formation and propagation of tau oligomeric seeds. Frontiers in neurology. vol 4. 2013-07-24. PMID:23882255. |
tau misfolding and aggregation leads to the formation of neurofibrillary tangles (nfts), which have long been considered one of the main pathological hallmarks for numerous neurodegenerative diseases known as tauopathies, including alzheimer's disease (ad) and parkinson's disease (pd). |
2013-07-24 |
2023-08-12 |
Not clear |
| Yan Ren, Naruhiko Sahar. Characteristics of tau oligomers. Frontiers in neurology. vol 4. 2013-07-24. PMID:23882258. |
in alzheimer disease (ad) and other tauopathies, microtubule-associated protein tau becomes hyperphosphorylated, undergoes conformational changes, aggregates, eventually becoming neurofibrillary tangles (nfts). |
2013-07-24 |
2023-08-12 |
Not clear |
| Tabea H Schauer, Maximilian Lochner, Gabor G Kovac. Nigral Tau pathology and striatal amyloid-β deposition does not correlate with striatal dopamine deficit in Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 12. 2013-07-22. PMID:22664779. |
nigral tau pathology and striatal amyloid-β deposition does not correlate with striatal dopamine deficit in alzheimer's disease. |
2013-07-22 |
2023-08-12 |
Not clear |
| Sangmook Lee, Thomas B She. Regulation of tau proteolysis by phosphatases. Brain research. vol 1495. 2013-07-22. PMID:23159717. |
one pathological hallmark of alzheimer's disease is the accumulation of highly phosphorylated tau. |
2013-07-22 |
2023-08-12 |
mouse |
| M Tajes, B Guivernau, E Ramos-Fernández, M Bosch-Morató, E Palomer, F X Guix, F J Muño. The pathophysiology of triose phosphate isomerase dysfunction in Alzheimer's disease. Histology and histopathology. vol 28. issue 1. 2013-07-22. PMID:23233058. |
alzheimer's disease (ad), the most prevalent neurodegenerative disease worldwide, has two main hallmarks: extracellular deposits of amyloid β-peptide (aβ) and intracellular neurofibrillary tangles composed by tau protein. |
2013-07-22 |
2023-08-12 |
Not clear |
| Chuang Guo, Pu Wang, Man-Li Zhong, Tao Wang, Xue-Shi Huang, Jia-Yi Li, Zhan-You Wan. Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain. Neurochemistry international. vol 62. issue 2. 2013-07-22. PMID:23262393. |
deferoxamine inhibits iron induced hippocampal tau phosphorylation in the alzheimer transgenic mouse brain. |
2013-07-22 |
2023-08-12 |
mouse |
| Chuang Guo, Pu Wang, Man-Li Zhong, Tao Wang, Xue-Shi Huang, Jia-Yi Li, Zhan-You Wan. Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain. Neurochemistry international. vol 62. issue 2. 2013-07-22. PMID:23262393. |
prior work has shown that iron interacts with hyperphosphorylated tau, which contributes to the formation of neurofibrillary tangles (nfts) in alzheimer's disease (ad), whereas iron chelator desferrioxamine (dfo) slows down the clinical progression of the cognitive decline associated with this disease. |
2013-07-22 |
2023-08-12 |
mouse |
| Reisuke H Takahashi, Estibaliz Capetillo-Zarate, Michael T Lin, Teresa A Milner, Gunnar K Goura. Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses. PloS one. vol 8. issue 1. 2013-07-22. PMID:23372648. |
pathologic aggregation of β-amyloid (aβ) peptide and the axonal microtubule-associated protein tau protein are hallmarks of alzheimer's disease (ad). |
2013-07-22 |
2023-08-12 |
mouse |
| Cassia R Overk, Sylvia E Perez, Chunqi Ma, Matthew D Taves, Kiran K Soma, Elliott J Mufso. Sex steroid levels and AD-like pathology in 3xTgAD mice. Journal of neuroendocrinology. vol 25. issue 2. 2013-07-12. PMID:22889357. |
decreases in testosterone and 17β-oestradiol (e(2)) are associated with an increased risk for alzheimer's disease (ad), which has been attributed to an increase in β-amyloid and tau pathological lesions. |
2013-07-12 |
2023-08-12 |
mouse |
| Wendy Noble, Diane P Hanger, Christopher C J Miller, Simon Loveston. The importance of tau phosphorylation for neurodegenerative diseases. Frontiers in neurology. vol 4. 2013-07-12. PMID:23847585. |
fibrillar deposits of highly phosphorylated tau are a key pathological feature of several neurodegenerative tauopathies including alzheimer's disease (ad) and some frontotemporal dementias. |
2013-07-12 |
2023-08-12 |
Not clear |
| Giulia M Sancesario, Maria T Cencioni, Zaira Esposito, Giovanna Borsellino, Marzia Nuccetelli, Alessandro Martorana, Luca Battistini, Roberto Sorge, Gianfranco Spalletta, Davide Ferrazzoli, Giorgio Bernardi, Sergio Bernardini, Giuseppe Sancesari. The load of amyloid-β oligomers is decreased in the cerebrospinal fluid of Alzheimer's disease patients. Journal of Alzheimer's disease : JAD. vol 31. issue 4. 2013-07-08. PMID:22717612. |
we evaluated whether an estimate of different species of aβ oligomers in the cerebrospinal fluid (csf) with or without dilution with ripa buffer could be more useful in the diagnosis of alzheimer's disease (ad) than the measurement of aβ42 monomers, total tau (t-tau), and phosphorylated tau (p-tau). |
2013-07-08 |
2023-08-12 |
Not clear |
| Masahiro Ono, Shun Hayashi, Kenji Matsumura, Hiroyuki Kimura, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, Hiroshi Mori, Hideo Saj. Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains. ACS chemical neuroscience. vol 2. issue 5. 2013-07-03. PMID:22778869. |
rhodanine and thiohydantoin derivatives for detecting tau pathology in alzheimer's brains. |
2013-07-03 |
2023-08-12 |
mouse |
| Masahiro Ono, Shun Hayashi, Kenji Matsumura, Hiroyuki Kimura, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, Hiroshi Mori, Hideo Saj. Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains. ACS chemical neuroscience. vol 2. issue 5. 2013-07-03. PMID:22778869. |
a novel series of rhodanin (rh) and thiohydantoin (th) derivatives were designed and synthesized for detecting tau pathology in the brains of patients with alzheimer's disease (ad). |
2013-07-03 |
2023-08-12 |
mouse |