All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
J A P van de Nes, S Konermann, R Nafe, D F Swaa. Beta-protein/A4 deposits are not associated with hyperphosphorylated tau in somatostatin neurons in the hypothalamus of Alzheimer's disease patients. Acta neuropathologica. vol 111. issue 2. 2007-10-30. PMID:16456666. beta-protein/a4 deposits are not associated with hyperphosphorylated tau in somatostatin neurons in the hypothalamus of alzheimer's disease patients. 2007-10-30 2023-08-12 human
Johannes Attems, Magdalena Quass, Kurt A Jellinge. Tau and alpha-synuclein brainstem pathology in Alzheimer disease: relation with extrapyramidal signs. Acta neuropathologica. vol 113. issue 1. 2007-10-26. PMID:17031655. tau and alpha-synuclein brainstem pathology in alzheimer disease: relation with extrapyramidal signs. 2007-10-26 2023-08-12 human
Sarita Lagalwar, Robert W Berry, Lester I Binde. Relation of hippocampal phospho-SAPK/JNK granules in Alzheimer's disease and tauopathies to granulovacuolar degeneration bodies. Acta neuropathologica. vol 113. issue 1. 2007-10-26. PMID:17089132. alzheimer's disease (ad), progressive supranuclear palsy (psp), corticobasal degeneration (cbd) and pick's disease (pid) all present with pathological lesions containing hyperphosphorylated filamentous tau protein; however, the location and type of lesion varies. 2007-10-26 2023-08-12 Not clear
Salvatore Spina, Jill R Murrell, Hirotaka Yoshida, Bernardino Ghetti, Niamh Bermingham, Brian Sweeney, Stephen R Dlouhy, R Anthony Crowther, Michel Goedert, Catherine Keohan. The novel Tau mutation G335S: clinical, neuropathological and molecular characterization. Acta neuropathologica. vol 113. issue 4. 2007-10-26. PMID:17186252. the pattern of pathological tau bands was like that of alzheimer disease. 2007-10-26 2023-08-12 Not clear
Carlo Ballatore, Virginia M-Y Lee, John Q Trojanowsk. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nature reviews. Neuroscience. vol 8. issue 9. 2007-10-26. PMID:17684513. advances in our understanding of the mechanisms of tau-mediated neurodegeneration in alzheimer's disease (ad) and related tauopathies, which are characterized by prominent cns accumulations of fibrillar tau inclusions, are rapidly moving this previously underexplored disease pathway to centre stage for disease-modifying drug discovery efforts. 2007-10-26 2023-08-12 Not clear
G Santpere, B Puig, I Ferre. Oxidative damage of 14-3-3 zeta and gamma isoforms in Alzheimer's disease and cerebral amyloid angiopathy. Neuroscience. vol 146. issue 4. 2007-10-25. PMID:17445990. the present study shows glycoxidative damage, as revealed with mono and bi-dimensional gel electrophoresis and western blotting, followed by in-gel digestion and mass spectrometry, in the frontal cortex in alzheimer's disease (ad) and cerebral amyloid angiopathy (caa), a neurodegenerative disease with deposition of abeta in cerebral blood vessels and in diffuse plaques unaccompanied by intraneuronal hyper-phosphorylated tau deposition. 2007-10-25 2023-08-12 Not clear
Junko Fujio, Hiroaki Hosono, Koichi Ishiguro, Shiro Ikegami, Shinobu C Fujit. Tau phosphorylation in the mouse brain during aversive conditioning. Neurochemistry international. vol 51. issue 2-4. 2007-10-25. PMID:17597257. these results suggest involvement of tau and tpki/gsk3beta phosphorylation in an early phase of memory formation in the hippocampus and amygdala, raising a possibility that a dysregulation of tau phosphorylation may underlie memory impairment in incipient alzheimer's disease. 2007-10-25 2023-08-12 mouse
Erin E Congdon, Mihaela Necula, Robert D Blackstone, Jeff Kure. Potency of a tau fibrillization inhibitor is influenced by its aggregation state. Archives of biochemistry and biophysics. vol 465. issue 1. 2007-10-24. PMID:17559794. tau fibrillization is a potential therapeutic target for alzheimer's and other neurodegenerative diseases. 2007-10-24 2023-08-12 Not clear
Malin E Andersson, Annica Sjölander, Niels Andreasen, Lennart Minthon, Oskar Hansson, Nenad Bogdanovic, Christina Jern, Katarina Jood, Anders Wallin, Kaj Blennow, Henrik Zetterber. Kinesin gene variability may affect tau phosphorylation in early Alzheimer's disease. International journal of molecular medicine. vol 20. issue 2. 2007-10-23. PMID:17611642. kinesin gene variability may affect tau phosphorylation in early alzheimer's disease. 2007-10-23 2023-08-12 Not clear
Shabnam Baig, Gordon K Wilcock, Seth Lov. Loss of perineuronal net N-acetylgalactosamine in Alzheimer's disease. Acta neuropathologica. vol 110. issue 4. 2007-10-19. PMID:16133543. we have investigated the relative preservation of wisteria floribunda agglutinin (wfa)-positive pns and parvalbumin-positive neurons in alzheimer's disease (ad), and the relationship of wfa-positive pns to parenchymal tau, amyloid beta-peptide (abeta) and mhc class ii antigen (a marker of activated microglia), in paraffin sections of 100 cases with ad and 45 controls. 2007-10-19 2023-08-12 Not clear
Laura Gasparini, Beatrice Terni, Maria Grazia Spillantin. Frontotemporal dementia with tau pathology. Neuro-degenerative diseases. vol 4. issue 2-3. 2007-10-12. PMID:17596718. filamentous deposits made of tau constitute a major defining characteristic of several neurodegenerative diseases known as tauopathies including alzheimer's disease. 2007-10-12 2023-08-12 Not clear
Sven Konzack, Edda Thies, Alexander Marx, Eva-Maria Mandelkow, Eckhard Mandelko. Swimming against the tide: mobility of the microtubule-associated protein tau in neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 37. 2007-10-11. PMID:17855606. tau protein stabilizes microtubule tracks, but in alzheimer's disease it aggregates and becomes missorted into the somatodendritic compartment. 2007-10-11 2023-08-12 Not clear
M Bibl, B Mollenhauer, S Wolf, H Esselmann, P Lewczuk, J Kornhuber, J Wiltfan. Reduced CSF carboxyterminally truncated Abeta peptides in frontotemporal lobe degenerations. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 5. 2007-10-09. PMID:17245538. cerebrospinal fluid (csf) carboxyterminally truncated amyloid-beta (abeta) peptides, abeta1-42 and tau protein were evaluated in 30 patients with frontotemporal lobe degenerations (ftld), 30 alzheimer's disease (ad) patients and 30 non-demented disease controls (ndc) by abeta-sds-page/immunoblot as well as commercial elisas for abeta1-42 and total tau. 2007-10-09 2023-08-12 Not clear
Josef Marksteiner, Hartmann Hinterhuber, Christian Humpe. Cerebrospinal fluid biomarkers for diagnosis of Alzheimer's disease: beta-amyloid(1-42), tau, phospho-tau-181 and total protein. Drugs of today (Barcelona, Spain : 1998). vol 43. issue 6. 2007-10-05. PMID:17612711. cerebrospinal fluid biomarkers for diagnosis of alzheimer's disease: beta-amyloid(1-42), tau, phospho-tau-181 and total protein. 2007-10-05 2023-08-12 Not clear
Josef Marksteiner, Hartmann Hinterhuber, Christian Humpe. Cerebrospinal fluid biomarkers for diagnosis of Alzheimer's disease: beta-amyloid(1-42), tau, phospho-tau-181 and total protein. Drugs of today (Barcelona, Spain : 1998). vol 43. issue 6. 2007-10-05. PMID:17612711. to date, the analysis of beta-amyloid(1-42), total tau and phospho-tau-181 from cerebrospinal fluid (csf) are the best biological markers to diagnose alzheimer's disease and differentiate it from other forms of dementia with a high reliability and validity. 2007-10-05 2023-08-12 Not clear
Salvatore Oddo, Antonella Caccamo, David Cheng, Bahareh Jouleh, Reidun Torp, Frank M LaFerl. Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice. Journal of neurochemistry. vol 102. issue 4. 2007-10-04. PMID:17472708. the two hallmark pathologies of alzheimer's disease (ad) are amyloid plaques, composed of the small amyloid-beta (abeta) peptide, and neurofibrillary tangles, comprised aggregates of the microtubule binding protein, tau. 2007-10-04 2023-08-12 mouse
Gregor Larbig, Marcus Pickhardt, David G Lloyd, Boris Schmidt, Eckhard Mandelko. Screening for inhibitors of tau protein aggregation into Alzheimer paired helical filaments: a ligand based approach results in successful scaffold hopping. Current Alzheimer research. vol 4. issue 3. 2007-10-02. PMID:17627489. screening for inhibitors of tau protein aggregation into alzheimer paired helical filaments: a ligand based approach results in successful scaffold hopping. 2007-10-02 2023-08-12 Not clear
Gregor Larbig, Marcus Pickhardt, David G Lloyd, Boris Schmidt, Eckhard Mandelko. Screening for inhibitors of tau protein aggregation into Alzheimer paired helical filaments: a ligand based approach results in successful scaffold hopping. Current Alzheimer research. vol 4. issue 3. 2007-10-02. PMID:17627489. the aggregation of tau protein into paired helical filaments is one of the hallmarks of alzheimer's disease and related dementias. 2007-10-02 2023-08-12 Not clear
F H Bouwman, W M van der Flier, N S M Schoonenboom, E J van Elk, A Kok, F Rijmen, M A Blankenstein, P Schelten. Longitudinal changes of CSF biomarkers in memory clinic patients. Neurology. vol 69. issue 10. 2007-09-28. PMID:17785669. in alzheimer disease (ad), longitudinal changes of beta-amyloid(1-42) (abeta(1-42)), tau, and phosphorylated tau at threonine 181 (ptau-181) in csf have been reported in small studies only. 2007-09-28 2023-08-12 Not clear
Diane P Hanger, Helen L Byers, Selina Wray, Kit-Yi Leung, Malcolm J Saxton, Anjan Seereeram, C Hugh Reynolds, Malcolm A Ward, Brian H Anderto. Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis. The Journal of biological chemistry. vol 282. issue 32. 2007-09-19. PMID:17562708. novel phosphorylation sites in tau from alzheimer brain support a role for casein kinase 1 in disease pathogenesis. 2007-09-19 2023-08-12 human