| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thierry S M Reijn, Marcel Olde Rikkert, Wieneke J A van Geel, Danielle de Jong, Marcel M Verbee. Diagnostic accuracy of ELISA and xMAP technology for analysis of amyloid beta(42) and tau proteins. Clinical chemistry. vol 53. issue 5. 2007-06-12. PMID:17395712. |
cerebrospinal fluid (csf) concentrations of amyloid beta(42) (abeta(42)) peptides and tau proteins may serve as biomarkers for alzheimer disease (ad). |
2007-06-12 |
2023-08-12 |
Not clear |
| Robert Adalbert, Jonathan Gilley, Michael P Colema. Abeta, tau and ApoE4 in Alzheimer's disease: the axonal connection. Trends in molecular medicine. vol 13. issue 4. 2007-06-11. PMID:17344096. |
abeta, tau and apoe4 in alzheimer's disease: the axonal connection. |
2007-06-11 |
2023-08-12 |
mouse |
| Robert Adalbert, Jonathan Gilley, Michael P Colema. Abeta, tau and ApoE4 in Alzheimer's disease: the axonal connection. Trends in molecular medicine. vol 13. issue 4. 2007-06-11. PMID:17344096. |
mutations in amyloid precursor protein (app), tau and apolipoprotein e4 (apoe4) lead to alzheimer's disease (ad) or related pathologies. |
2007-06-11 |
2023-08-12 |
mouse |
| Hiroyuki Ara. [From neuropathology to biomarker development in Alzheimer research]. Rinsho shinkeigaku = Clinical neurology. vol 46. issue 11. 2007-06-11. PMID:17432224. |
recent advances in our understanding of neurobiology of alzheimer's disease (ad) demonstrate that ad starts with accumulation of amyloid beta-protein (abeta) followed by abnormal phosphorylation of tau protein and a massive neuron death in vulnerable brain areas. |
2007-06-11 |
2023-08-12 |
mouse |
| Michael R Sawaya, Shilpa Sambashivan, Rebecca Nelson, Magdalena I Ivanova, Stuart A Sievers, Marcin I Apostol, Michael J Thompson, Melinda Balbirnie, Jed J W Wiltzius, Heather T McFarlane, Anders Ø Madsen, Christian Riekel, David Eisenber. Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature. vol 447. issue 7143. 2007-06-07. PMID:17468747. |
these include segments from the alzheimer's amyloid-beta and tau proteins, the prp prion protein, insulin, islet amyloid polypeptide (iapp), lysozyme, myoglobin, alpha-synuclein and beta(2)-microglobulin, suggesting that common structural features are shared by amyloid diseases at the molecular level. |
2007-06-07 |
2023-08-12 |
Not clear |
| Qing-Guo Ren, Xiao-Mei Liao, Xiao-Qian Chen, Gong-Ping Liu, Jian-Zhi Wan. Effects of tau phosphorylation on proteasome activity. FEBS letters. vol 581. issue 7. 2007-06-06. PMID:17376439. |
dysfunction of proteasome contributes to the accumulation of the abnormally hyperphosphorylated tau in alzheimer's disease. |
2007-06-06 |
2023-08-12 |
Not clear |
| Tong Li, Hemant K Paude. 14-3-3zeta facilitates GSK3beta-catalyzed tau phosphorylation in HEK-293 cells by a mechanism that requires phosphorylation of GSK3beta on Ser9. Neuroscience letters. vol 414. issue 3. 2007-06-05. PMID:17317006. |
hyperphosphorylated tau is the prominent component of paired helical filaments, which are the major component of neurofibrillary tangles associated with alzheimer's disease (ad). |
2007-06-05 |
2023-08-12 |
cattle |
| Li-Wen Ko, Jayanarayan G Kulathingal, Shu-Hui C Ye. Cytosine beta-D-arabinofuranoside used as a paradigm modifier to increase production of tau aggregates in a cellular model of tauopathy. Neurochemical research. vol 32. issue 4-5. 2007-05-29. PMID:17151917. |
intraneuronal deposition of filamentous tau is a hallmark of alzheimer's disease (ad) and related tauopathies. |
2007-05-29 |
2023-08-12 |
Not clear |
| Rostislav Skrabana, Jozef Sevcik, Michal Nova. Intrinsically disordered proteins in the neurodegenerative processes: formation of tau protein paired helical filaments and their analysis. Cellular and molecular neurobiology. vol 26. issue 7-8. 2007-05-24. PMID:16779670. |
among them, alpha-synuclein is involved in parkinson's disease, prion protein in transmissible spongiform encephalopathies, and tau protein in alzheimer's disease (ad) and related tauopathies. |
2007-05-24 |
2023-08-12 |
Not clear |
| Yolande A L Pijnenburg, John C Janssen, Niki S M Schoonenboom, Axel Petzold, Cees Mulder, Torgny Stigbrand, Niklas Norgren, Hans Heijst, C Erik Hack, Philip Scheltens, Charlotte E Teunisse. CSF neurofilaments in frontotemporal dementia compared with early onset Alzheimer's disease and controls. Dementia and geriatric cognitive disorders. vol 23. issue 4. 2007-05-24. PMID:17290105. |
we therefore measured csf neurofilament profiles in patients with ftd, patients with early onset alzheimer's disease (ead) and healthy control subjects to explore the discriminative potential of csf neurofilaments compared with the existing csf biomarkers amyloid-beta(1-42), tau and tau phosphorylated at threonine-181. |
2007-05-24 |
2023-08-12 |
human |
| Wladimir Labeikovsky, Elan Z Eisenmesser, Daryl A Bosco, Dorothee Ker. Structure and dynamics of pin1 during catalysis by NMR. Journal of molecular biology. vol 367. issue 5. 2007-05-24. PMID:17316687. |
pin1 has been shown to be essential for cell-cycle progression and to interact with the neuronal tau protein inhibiting its aggregation into fibrillar tangles as found in alzheimer's disease. |
2007-05-24 |
2023-08-12 |
Not clear |
| Erik D Roberson, Kimberly Scearce-Levie, Jorge J Palop, Fengrong Yan, Irene H Cheng, Tiffany Wu, Hilary Gerstein, Gui-Qiu Yu, Lennart Muck. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science (New York, N.Y.). vol 316. issue 5825. 2007-05-21. PMID:17478722. |
reducing endogenous tau ameliorates amyloid beta-induced deficits in an alzheimer's disease mouse model. |
2007-05-21 |
2023-08-12 |
mouse |
| Erik D Roberson, Kimberly Scearce-Levie, Jorge J Palop, Fengrong Yan, Irene H Cheng, Tiffany Wu, Hilary Gerstein, Gui-Qiu Yu, Lennart Muck. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science (New York, N.Y.). vol 316. issue 5825. 2007-05-21. PMID:17478722. |
thus, tau reduction can block abeta- and excitotoxin-induced neuronal dysfunction and may represent an effective strategy for treating alzheimer's disease and related conditions. |
2007-05-21 |
2023-08-12 |
mouse |
| Kaoru Sugimori, Katsuji Kobayashi, Tatsuru Kitamura, Satoru Sudo, Yoshifumi Koshin. 14-3-3 protein beta isoform is associated with 3-repeat tau neurofibrillary tangles in Alzheimer's disease. Psychiatry and clinical neurosciences. vol 61. issue 2. 2007-05-14. PMID:17362433. |
14-3-3 protein beta isoform is associated with 3-repeat tau neurofibrillary tangles in alzheimer's disease. |
2007-05-14 |
2023-08-12 |
Not clear |
| Kaoru Sugimori, Katsuji Kobayashi, Tatsuru Kitamura, Satoru Sudo, Yoshifumi Koshin. 14-3-3 protein beta isoform is associated with 3-repeat tau neurofibrillary tangles in Alzheimer's disease. Psychiatry and clinical neurosciences. vol 61. issue 2. 2007-05-14. PMID:17362433. |
14-3-3 proteins play roles in phosphorylation of tau proteins in neurofibrillary tangles (nft) in alzheimer's disease (ad). |
2007-05-14 |
2023-08-12 |
Not clear |
| Spiridon Papapetropoulos, Matthew J Farrer, Jeremy T Stone, Nicole M Milkovic, Owen A Ross, Linda Calvo, Donald McQuorquodale, Deborah C Mas. Phenotypic associations of tau and ApoE in Parkinson's disease. Neuroscience letters. vol 414. issue 2. 2007-05-08. PMID:17204369. |
to explore possible phenotypic implications, we studied common tau and apoe gene polymorphisms, associated with alzheimer's disease (ad), progressive supranuclear palsy (psp) and pd, in a clinically and pathologically characterized cohort of pd patients and aged control subjects. |
2007-05-08 |
2023-08-12 |
human |
| Chad A Dickey, Adeela Kamal, Karen Lundgren, Natalia Klosak, Rachel M Bailey, Judith Dunmore, Peter Ash, Sareh Shoraka, Jelena Zlatkovic, Christopher B Eckman, Cam Patterson, Dennis W Dickson, N Stanley Nahman, Michael Hutton, Francis Burrows, Leonard Petrucell. The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. The Journal of clinical investigation. vol 117. issue 3. 2007-05-04. PMID:17304350. |
a primary pathologic component of alzheimer's disease (ad) is the formation of neurofibrillary tangles composed of hyperphosphorylated tau (p-tau). |
2007-05-04 |
2023-08-12 |
mouse |
| Dmitry Goryunov, Ronald K H Lie. CHIP-ping away at tau. The Journal of clinical investigation. vol 117. issue 3. 2007-05-04. PMID:17332887. |
in alzheimer's disease (ad), a hyperphosphorylated form of the protein tau (p-tau) forms intracellular inclusions known as neurofibrillary tangles. |
2007-05-04 |
2023-08-12 |
Not clear |
| Steffen Albrecht, Martine Bourdeau, David Bennett, Elliott J Mufson, Meena Bhattacharjee, Andréa C LeBlan. Activation of caspase-6 in aging and mild cognitive impairment. The American journal of pathology. vol 170. issue 4. 2007-05-04. PMID:17392160. |
active caspase-6 (csp6) and tau cleaved by csp6 (taudeltacsp6) are abundant in neuritic plaques (nps), neuropil threads (npts), and neurofibrillary tangles (nfts) in end-stage alzheimer's disease (ad) (guo h, albrecht s, bourdeau m, petzke t, bergeron c, leblanc ac: active caspase-6 and caspase-6 cleaved tau in neuropil threads, neuritic plaques and neurofibrillary tangles of alzheimer's disease. |
2007-05-04 |
2023-08-12 |
human |
| Steffen Albrecht, Martine Bourdeau, David Bennett, Elliott J Mufson, Meena Bhattacharjee, Andréa C LeBlan. Activation of caspase-6 in aging and mild cognitive impairment. The American journal of pathology. vol 170. issue 4. 2007-05-04. PMID:17392160. |
given the ability of active csp6 to increase amyloid-beta peptide production and cleave tau and several synaptic proteins (leblanc ac, liu h, goodyer c, bergeron c, hammond j: caspase-6 role in apoptosis of human neurons, amyloidogenesis and alzheimer's disease. |
2007-05-04 |
2023-08-12 |
human |