All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Pamela J McMillan, Sarah J Benbow, Rikki Uhrich, Aleen Saxton, Misa Baum, Timothy Strovas, Jeanna M Wheeler, Jeremy Baker, Nicole F Liachko, C Dirk Keene, Caitlin S Latimer, Brian C Kraeme. Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change. Brain : a journal of neurology. 2023-02-02. PMID:36732296. alzheimer's disease and related disorders feature neurofibrillary tangles and other neuropathological lesions composed of detergent-insoluble tau protein. 2023-02-02 2023-08-14 mouse
Pamela J McMillan, Sarah J Benbow, Rikki Uhrich, Aleen Saxton, Misa Baum, Timothy Strovas, Jeanna M Wheeler, Jeremy Baker, Nicole F Liachko, C Dirk Keene, Caitlin S Latimer, Brian C Kraeme. Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change. Brain : a journal of neurology. 2023-02-02. PMID:36732296. trc35 exhibits specificity for alzheimer's disease-derived detergent insoluble tau relative to soluble recombinant tau. 2023-02-02 2023-08-14 mouse
Itika Saha, Patricia Yuste-Checa, Miguel Da Silva Padilha, Qiang Guo, Roman Körner, Hauke Holthusen, Victoria A Trinkaus, Irina Dudanova, Rubén Fernández-Busnadiego, Wolfgang Baumeister, David W Sanders, Saurabh Gautam, Marc I Diamond, F Ulrich Hartl, Mark S Hip. The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system. Nature communications. vol 14. issue 1. 2023-02-02. PMID:36732333. amyloid-like aggregates of the microtubule-associated protein tau are associated with several neurodegenerative disorders including alzheimer's disease. 2023-02-02 2023-08-14 Not clear
Lulu Jiang, Pijush Chakraborty, Lushuang Zhang, Melissa Wong, Shannon E Hill, Chelsea Joy Webber, Jenna Libera, Laura J Blair, Benjamin Wolozin, Markus Zweckstette. Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress. Science advances. vol 9. issue 5. 2023-02-01. PMID:36724228. alzheimer's disease and related tauopathies are characterized by the pathogenic misfolding and aggregation of the microtubule-associated protein tau. 2023-02-01 2023-08-14 mouse
Jie Wen, Yangyang Wang, Chuanling Wang, Minghao Yuan, Fei Chen, Qian Zou, Zhiyou Cai, Bin Zha. Dietary High-Fat Promotes Cognitive Impairment by Suppressing Mitophagy. Oxidative medicine and cellular longevity. vol 2023. 2023-01-31. PMID:36718278. dietary habits contribute to the characteristics of alzheimer's disease (ad) and cognitive impairment, which are partly induced by the accumulation of hyperphosphorylated tau, a microtubule-associated protein. 2023-01-31 2023-08-14 mouse
Anne-Marie Jacobsen, Nico C van de Merbel, Dorte K Ditlevsen, Ketil Tvermosegaard, Frank Schalk, Wietske Lambert, Christoffer Bundgaard, Jan T Pedersen, Nina Rosenqvis. A Quantitative LC-MS/MS Method for Distinguishing the Tau Protein Forms Phosphorylated and Nonphosphorylated at Serine-396. Journal of the American Society for Mass Spectrometry. 2023-01-31. PMID:36719168. hyperphosphorylated tau protein is well-known to be involved in the formation of neurofibrillary tangles and the progression of age-related neurodegenerative diseases (tauopathies), including alzheimer's disease (ad). 2023-01-31 2023-08-14 mouse
Christopher Pham Pacia, Jinyun Yuan, Yimei Yue, Eric C Leuthardt, Tammie L S Benzinger, Arash Nazeri, Hong Che. Focused Ultrasound-mediated Liquid Biopsy in a Tauopathy Mouse Model. Radiology. 2023-01-31. PMID:36719290. background neurodegenerative disorders (such as alzheimer disease) characterized by the deposition of various pathogenic forms of tau protein in the brain are collectively referred to as tauopathies. 2023-01-31 2023-08-14 mouse
Emily A Largent, Joshua Grill, Kyra O'Brien, David Wolk, Kristin Harkins, Jason Karlawis. Testing for Alzheimer Disease Biomarkers and Disclosing Results Across the Disease Continuum. Neurology. 2023-01-31. PMID:36720642. three pathological processes define or are characteristic of alzheimer's disease (ad): amyloid-β, hyperphosphorylated tau, and neurodegeneration. 2023-01-31 2023-08-14 human
Cherie Strikwerda-Brown, Hazal Ozlen, Alexa Pichet Binette, Marianne Chapleau, Natalie L Marchant, John C S Breitner, Sylvia Villeneuv. Trait Mindfulness Is Associated With Less Amyloid, Tau, and Cognitive Decline in Individuals at Risk for Alzheimer's Disease. Biological psychiatry global open science. vol 3. issue 1. 2023-01-30. PMID:36712573. trait mindfulness is associated with less amyloid, tau, and cognitive decline in individuals at risk for alzheimer's disease. 2023-01-30 2023-08-14 Not clear
Tushar Dubey, Preethi Kushawa, H V Thulasiram, Madhura Chandrashekar, Subashchandrabose Chinnathamb. Bacopa monnieri reduces Tau aggregation and Tau-mediated toxicity in cells. International journal of biological macromolecules. 2023-01-30. PMID:36716837. the overall results of the present study suggested that bacopa monnieri could be considered a potent herb against tau phosphorylation and tau aggregation, which projects it as a promising formulation for alzheimer's disease. 2023-01-30 2023-08-14 Not clear
Longfei Li, Jin Miao, Yanli Jiang, Chun-Ling Dai, Khalid Iqbal, Fei Liu, Dandan Ch. Passive immunization inhibits tau phosphorylation and improves recognition learning and memory in 3xTg-AD mice. Experimental neurology. 2023-01-30. PMID:36717015. tau pathology is essential in the pathogenesis of alzheimer's disease (ad) and related tauopathies. 2023-01-30 2023-08-14 mouse
Natasha Krishnadas, Vincent Doré, Joanne S Robertson, Larry Ward, Christopher Fowler, Colin L Masters, Pierrick Bourgeat, Jurgen Fripp, Victor L Villemagne, Christopher C Row. Rates of regional tau accumulation in ageing and across the Alzheimer's disease continuum: an AIBL EBioMedicine. vol 88. 2023-01-29. PMID:36709581. rates of regional tau accumulation in ageing and across the alzheimer's disease continuum: an aibl tau positron emission tomography (pet) imaging enables longitudinal observation of tau accumulation in alzheimer's disease (ad). 2023-01-29 2023-08-14 Not clear
Inès R H Ben-Nejma, Aneta J Keliris, Verdi Vanreusel, Peter Ponsaerts, Annemie Van der Linden, Georgios A Keliri. Altered dynamics of glymphatic flow in a mature-onset Tet-off APP mouse model of amyloidosis. Alzheimer's research & therapy. vol 15. issue 1. 2023-01-28. PMID:36707887. alzheimer's disease (ad) is an incurable neurodegenerative disorder characterised by the progressive buildup of toxic amyloid-beta (aβ) and tau protein aggregates eventually leading to cognitive decline. 2023-01-28 2023-08-14 mouse
Edoardo Nicolò Aiello, Federico Verde, Federica Solca, Ilaria Milone, Eleonora Giacopuzzi Grigoli, Antonella Dubini, Antonia Ratti, Roberta Ferrucci, Erminio Torresani, Alberto Priori, Nicola Ticozzi, Vincenzo Silani, Barbara Polett. Lower semantic fluency scores and a phonemic-over-semantic advantage predict abnormal CSF P-tau Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-01-27. PMID:36705785. lower semantic fluency scores and a phonemic-over-semantic advantage predict abnormal csf p-tau the present study aimed to determine whether patients with mild cognitive impairment (mci) and dementia due to alzheimer's disease (ad), semantic verbal fluency (svf), and the semantic-phonemic discrepancy (spd) could predict abnormal cerebrospinal fluid (csf) phosphorylated tau (p-tau 2023-01-27 2023-08-14 Not clear
Andrej Kováč, Petra Majerová, Marianna Nytka, Monika Zajacová Cechová, Petr Bednář, Roman Hájek, Dale A Cooper-Shepherd, Alexander Muck, Karel Lem. Separation of Isomeric Tau Phosphopeptides from Alzheimer's Disease Brain by Cyclic Ion Mobility Mass Spectrometry. Journal of the American Society for Mass Spectrometry. 2023-01-27. PMID:36706338. separation of isomeric tau phosphopeptides from alzheimer's disease brain by cyclic ion mobility mass spectrometry. 2023-01-27 2023-08-14 Not clear
Xin Wang, Iris Broce, Yuqi Qiu, Kacie D Deters, Chun Chieh Fan, Anders M Dale, Steven D Edland, Sarah J Bank. A simple genetic stratification method for lower cost, more expedient clinical trials in early Alzheimer's disease: A preliminary study of tau PET and cognitive outcomes. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-01-26. PMID:36701211. a simple genetic stratification method for lower cost, more expedient clinical trials in early alzheimer's disease: a preliminary study of tau pet and cognitive outcomes. 2023-01-26 2023-08-14 Not clear
Xin Wang, Iris Broce, Yuqi Qiu, Kacie D Deters, Chun Chieh Fan, Anders M Dale, Steven D Edland, Sarah J Bank. A simple genetic stratification method for lower cost, more expedient clinical trials in early Alzheimer's disease: A preliminary study of tau PET and cognitive outcomes. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-01-26. PMID:36701211. identifying individuals who are most likely to accumulate tau and exhibit cognitive decline is critical for alzheimer's disease (ad) clinical trials. 2023-01-26 2023-08-14 Not clear
Hassan Ainani, Najat Bouchmaa, Reda Ben Mrid, Rachid El Fatim. Liquid-liquid phase separation of protein tau: An emerging process in Alzheimer's disease pathogenesis. Neurobiology of disease. 2023-01-26. PMID:36702317. liquid-liquid phase separation of protein tau: an emerging process in alzheimer's disease pathogenesis. 2023-01-26 2023-08-14 Not clear
Hassan Ainani, Najat Bouchmaa, Reda Ben Mrid, Rachid El Fatim. Liquid-liquid phase separation of protein tau: An emerging process in Alzheimer's disease pathogenesis. Neurobiology of disease. 2023-01-26. PMID:36702317. tau protein is known as a major neurofibrillary tangles component in alzheimer's disease (ad). 2023-01-26 2023-08-14 Not clear
Joo-Hee Lee, Nivethasri Lakshmana Perumal, Sehee Kwon, Hee-Cheol Kim, Na-Hyun Ahn, Su-Bin Choi, Eunjin Hwang, Hyoryeong Song, David R Elmaleh, Aryun Kim, Woong-Suk Yang, Cheorl-Ho Kim, Byeong-Churl Jang, Sungwoon Choi, Seung-Hoon Yan. The derivatives of cromolyn ameliorate the abnormal misfolding of amyloid proteins and neuroinflammation in the neural cells. Current medicinal chemistry. 2023-01-25. PMID:36694324. the representative symptom of alzheimer's disease (ad) has mainly been mentioned to be misfolding of amyloid proteins, such as amyloid-beta (aβ) and tau protein. 2023-01-25 2023-08-14 Not clear