All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Sergey Shcherbinin, Cynthia D Evans, Ming Lu, Scott W Andersen, Michael J Pontecorvo, Brian A Willis, Ivelina Gueorguieva, Paula M Hauck, Dawn A Brooks, Mark A Mintun, John R Sim. Association of Amyloid Reduction After Donanemab Treatment With Tau Pathology and Clinical Outcomes: The TRAILBLAZER-ALZ Randomized Clinical Trial. JAMA neurology. 2022-09-12. PMID:36094645. β-amyloid plaques and neurofibrillary tau deposits biologically define alzheimer disease. 2022-09-12 2023-08-14 Not clear
Masoume Alipour, Majid Tebianian, Nahid Tofigh, Reyhaneh Sadat Taheri, Sayed Alireza Mousavi, Asal Naseri, Amin Ahmadi, Nayla Munawar, Koorosh Shahpasan. Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models. Neuropeptides. vol 96. 2022-09-10. PMID:36087426. traumatic brain injury (tbi), characterized by acute neurological impairment, is associated with a higher incidence of neurodegenerative diseases, particularly chronic traumatic encephalopathy (cte), alzheimer's disease (ad), and parkinson's disease (pd), whose hallmarks include hyperphosphorylated tau protein. 2022-09-10 2023-08-14 mouse
Rong Shi, Luyao Wang, Jiehui Jian. An unsupervised region of interest extraction model for tau PET images and its application in the diagnosis of Alzheimer's disease. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-09. PMID:36083928. an unsupervised region of interest extraction model for tau pet images and its application in the diagnosis of alzheimer's disease. 2022-09-09 2023-08-14 Not clear
Rong Shi, Luyao Wang, Jiehui Jian. An unsupervised region of interest extraction model for tau PET images and its application in the diagnosis of Alzheimer's disease. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-09. PMID:36083928. recently, tau positron-emission tomography (pet) images have been widely used for the diagnosis of alzheimer's disease (ad). 2022-09-09 2023-08-14 Not clear
Colin Groot, Ruben Smith, Erik Stomrud, Alexa Pichet Binette, Antoine Leuzy, Anika Wuestefeld, Laura E M Wisse, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Shorena Janelidze, Olof Strandberg, Rik Ossenkoppele, Oskar Hansso. Phospho-tau with subthreshold tau-PET predicts increased tau accumulation rates in amyloid-positive individuals. Brain : a journal of neurology. 2022-09-09. PMID:36084009. different tau biomarkers become abnormal at different stages of alzheimer's disease, with csf phospho-tau typically becoming elevated at subthreshold levels of tau-pet binding. 2022-09-09 2023-08-14 Not clear
Colin Groot, Ruben Smith, Erik Stomrud, Alexa Pichet Binette, Antoine Leuzy, Anika Wuestefeld, Laura E M Wisse, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Shorena Janelidze, Olof Strandberg, Rik Ossenkoppele, Oskar Hansso. Phospho-tau with subthreshold tau-PET predicts increased tau accumulation rates in amyloid-positive individuals. Brain : a journal of neurology. 2022-09-09. PMID:36084009. while this suggests that the tau-discordant biomarker profile is not strongly associated with short-term clinical decline, this group does represent an interesting population for monitoring effects of interventions with disease modifying agents on tau accumulation in early alzheimer's disease, and for examining the emergence of tau aggregates in alzheimer's disease. 2022-09-09 2023-08-14 Not clear
Dustin B Hammers, Ralitsa V Kostadinova, Robert J Spencer, Jean N Ikanga, Frederick W Unverzagt, Shannon L Risacher, Liana G Apostolov. Sensitivity of memory subtests and learning slopes from the ADAS-Cog to distinguish along the continuum of the NIA-AA Research Framework for Alzheimer's Disease. Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition. 2022-09-08. PMID:36074015. all participants were categorized using the nia-aa research framework - based on pet-imaging of β-amyloid (a) and tau (t) deposition - as normal ad biomarkers (a-t-), alzheimer's pathologic change (a + t-), or alzheimer's disease (a + t+). 2022-09-08 2023-08-14 human
Sehnaz Ferdosh, Senjuti Banerjee, Chandana Bara. Amplification of Amyloid Protein-induced Aggregation of the Eukaryotic Ribosome. Protein and peptide letters. 2022-09-06. PMID:36065931. alzheimer's disease (ad) is characterized by the aggregation of tau protein and amyloid-β peptides (aβ 1-40 and aβ 1-42). 2022-09-06 2023-08-14 Not clear
Iris E Jansen, Sven J van der Lee, Duber Gomez-Fonseca, Itziar de Rojas, Maria Carolina Dalmasso, Benjamin Grenier-Boley, Anna Zettergren, Aniket Mishra, Muhammad Ali, Victor Andrade, Céline Bellenguez, Luca Kleineidam, Fahri Küçükali, Yun Ju Sung, Niccolo Tesí, Ellen M Vromen, Douglas P Wightman, Daniel Alcolea, Montserrat Alegret, Ignacio Alvarez, Philippe Amouyel, Lavinia Athanasiu, Shahram Bahrami, Henri Bailly, Olivia Belbin, Sverre Bergh, Lars Bertram, Geert Jan Biessels, Kaj Blennow, Rafael Blesa, Mercè Boada, Anne Boland, Katharina Buerger, Ángel Carracedo, Laura Cervera-Carles, Geneviève Chene, Jurgen A H R Claassen, Stephanie Debette, Jean-Francois Deleuze, Peter Paul de Deyn, Janine Diehl-Schmid, Srdjan Djurovic, Oriol Dols-Icardo, Carole Dufouil, Emmanuelle Duron, Emrah Düzel, Tormod Fladby, Juan Fortea, Lutz Frölich, Pablo García-González, Maria Garcia-Martinez, Ina Giegling, Oliver Goldhardt, Johan Gobom, Timo Grimmer, Annakaisa Haapasalo, Harald Hampel, Olivier Hanon, Lucrezia Hausner, Stefanie Heilmann-Heimbach, Seppo Helisalmi, Michael T Heneka, Isabel Hernández, Sanna-Kaisa Herukka, Henne Holstege, Jonas Jarholm, Silke Kern, Anne-Brita Knapskog, Anne M Koivisto, Johannes Kornhuber, Teemu Kuulasmaa, Carmen Lage, Christoph Laske, Ville Leinonen, Piotr Lewczuk, Alberto Lleó, Adolfo López de Munain, Sara Lopez-Garcia, Wolfgang Maier, Marta Marquié, Merel O Mol, Laura Montrreal, Fermin Moreno, Sonia Moreno-Grau, Gael Nicolas, Markus M Nöthen, Adelina Orellana, Lene Pålhaugen, Janne M Papma, Florence Pasquier, Robert Perneczky, Oliver Peters, Yolande A L Pijnenburg, Julius Popp, Danielle Posthuma, Ana Pozueta, Josef Priller, Raquel Puerta, Inés Quintela, Inez Ramakers, Eloy Rodriguez-Rodriguez, Dan Rujescu, Ingvild Saltvedt, Pascual Sanchez-Juan, Philip Scheltens, Norbert Scherbaum, Matthias Schmid, Anja Schneider, Geir Selbæk, Per Selnes, Alexey Shadrin, Ingmar Skoog, Hilkka Soininen, Lluís Tárraga, Stefan Teipel, Betty Tijms, Magda Tsolaki, Christine Van Broeckhoven, Jasper Van Dongen, John C van Swieten, Rik Vandenberghe, Jean-Sébastien Vidal, Pieter J Visser, Jonathan Vogelgsang, Margda Waern, Michael Wagner, Jens Wiltfang, Mandy M J Wittens, Henrik Zetterberg, Miren Zulaica, Cornelia M van Duijn, Maria Bjerke, Sebastiaan Engelborghs, Frank Jessen, Charlotte E Teunissen, Pau Pastor, Mikko Hiltunen, Martin Ingelsson, Ole A Andreassen, Jordi Clarimón, Kristel Sleegers, Agustín Ruiz, Alfredo Ramirez, Carlos Cruchaga, Jean-Charles Lambert, Wiesje van der Flie. Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta neuropathologica. 2022-09-06. PMID:36066633. amyloid-beta 42 (aβ42) and phosphorylated tau (ptau) levels in cerebrospinal fluid (csf) reflect core features of the pathogenesis of alzheimer's disease (ad) more directly than clinical diagnosis. 2022-09-06 2023-08-14 Not clear
Zhen-Kai Ngian, Yow-Yong Tan, Ching-Thong Choo, Wei-Qi Lin, Chao-Yong Leow, Shan-Jie Mah, Mitchell Kim-Peng Lai, Christopher Li-Hsian Chen, Chin-Tong On. Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 37. 2022-09-06. PMID:36067305. truncated tau caused by intron retention is enriched in alzheimer's disease cortex and exhibits altered biochemical properties. 2022-09-06 2023-08-14 Not clear
Zhen-Kai Ngian, Yow-Yong Tan, Ching-Thong Choo, Wei-Qi Lin, Chao-Yong Leow, Shan-Jie Mah, Mitchell Kim-Peng Lai, Christopher Li-Hsian Chen, Chin-Tong On. Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 37. 2022-09-06. PMID:36067305. alzheimer's disease (ad) is characterized by the accumulation of amyloid-β plaques and tau tangles in brain tissues. 2022-09-06 2023-08-14 Not clear
Aocai Yang, Lei Du, Wenwen Gao, Bing Liu, Yue Chen, Yige Wang, Xiuxiu Liu, Kuan Lv, Wenwei Zhang, Hui Xia, Kai Wu, Guolin M. Associations of cortical iron accumulation with cognition and cerebral atrophy in Alzheimer's disease. Quantitative imaging in medicine and surgery. vol 12. issue 9. 2022-09-05. PMID:36060596. in alzheimer's disease (ad), cerebral iron accumulation colocalizes with the pathological proteins amyloid-β (aβ) and tau. 2022-09-05 2023-08-14 Not clear
Masoumeh Gharb, Amideddin Nouralishahi, Ali Riazi, Gholamhossein Riaz. Inhibition Of Tau Protein Aggregation By a Chaperone-like β-Boswellic Acid Conjugated To Gold Nanoparticles. ACS omega. vol 7. issue 34. 2022-09-05. PMID:36061732. a potential therapeutic strategy to inhibit tau protein aggregation in neurons has substantial effects on preventing or controlling alzheimer's disease (ad). 2022-09-05 2023-08-14 Not clear
Qingling Sun, Jingnian Ni, Mingqing Wei, Siwei Long, Ting Li, Dongsheng Fan, Tao Lu, Jing Shi, Jinzhou Tia. Plasma β-amyloid, tau, neurodegeneration biomarkers and inflammatory factors of probable Alzheimer's disease dementia in Chinese individuals. Frontiers in aging neuroscience. vol 14. 2022-09-05. PMID:36062146. plasma β-amyloid, tau, neurodegeneration biomarkers and inflammatory factors of probable alzheimer's disease dementia in chinese individuals. 2022-09-05 2023-08-14 Not clear
Qingling Sun, Jingnian Ni, Mingqing Wei, Siwei Long, Ting Li, Dongsheng Fan, Tao Lu, Jing Shi, Jinzhou Tia. Plasma β-amyloid, tau, neurodegeneration biomarkers and inflammatory factors of probable Alzheimer's disease dementia in Chinese individuals. Frontiers in aging neuroscience. vol 14. 2022-09-05. PMID:36062146. plasma-derived β-amyloid, tau, and neurodegeneration (atn) biomarkers can accurately diagnose alzheimer's disease (ad) and predict its progression. 2022-09-05 2023-08-14 Not clear
Wendy Aquino Nunez, Benjamin Combs, T Chris Gamblin, Brian D Ackle. Age-dependent accumulation of tau aggregation in Frontiers in aging. vol 3. 2022-09-05. PMID:36062211. age-dependent accumulation of tau aggregation in aging is the primary risk factor for alzheimer's disease (ad) and related disorders (adrds). 2022-09-05 2023-08-14 Not clear
Nana Jin, Jianlan Gu, Ruozhen Wu, Dandan Chu, Yunn Chyn Tung, Jerzy Wegiel, Thomas Wisniewski, Cheng-Xin Gong, Khalid Iqbal, Fei Li. Tau seeding activity in various regions of down syndrome brain assessed by two novel assays. Acta neuropathologica communications. vol 10. issue 1. 2022-09-05. PMID:36064460. propagation of tau pathology via the seeding of naive tau aggregation underlies the progression of alzheimer's disease (ad) and related tauopathies. 2022-09-05 2023-08-14 Not clear
Moorthi Ponnusamy, Shuai Wang, Melike Yuksel, Mitchell T Hansen, Danielle M Blazier, Joseph D McMillan, Xiaolin Zhang, Eric B Dammer, Lisa Collier, Gopal Thinakara. Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model. Brain : a journal of neurology. 2022-09-04. PMID:36059072. ps19 mice develop age-dependent tau neuropathology and motor deficits and are commonly used to study alzheimer's disease tau pathophysiology. 2022-09-04 2023-08-14 mouse
Boris-Stephan Rauchmann, Matthias Brendel, Nicolai Franzmeier, Lena Trappmann, Mirlind Zaganjori, Ersin Ersoezlue, Estrella Morenas-Rodriguez, Selim Guersel, Lena Burow, Carolin Kurz, Jan Haeckert, Maia Tatò, Julia Utecht, Boris Papazov, Oliver Pogarell, Daniel Janowitz, Katharina Buerger, Michael Ewers, Carla Palleis, Endy Weidinger, Gloria Biechele, Sebastian Schuster, Anika Finze, Florian Eckenweber, Rainer Rupprecht, Axel Rominger, Oliver Goldhardt, Timo Grimmer, Daniel Keeser, Sophia Stoecklein, Olaf Dietrich, Peter Bartenstein, Johannes Levin, Günter Höglinger, Robert Perneczk. Microglial Activation and Connectivity in Alzheimer Disease and Aging. Annals of neurology. 2022-09-02. PMID:36053756. alzheimer disease (ad) is characterized by amyloid β (aβ) plaques and neurofibrillary tau tangles, but increasing evidence suggests that neuroinflammation also plays a key role, driven by the activation of microglia. 2022-09-02 2023-08-14 Not clear
Keith A Josephs, Nirubol Tosakulwong, Rodolfo G Gatto, Stephen D Weigand, Farwa Ali, Hugo Botha, Jonathan Graff-Radford, Mary M Machulda, Rodolfo Savica, Christopher G Schwarz, Matthew L Senjem, Bradley F Boeve, Kejal Kantarci, David T Jones, Vijay K Ramanan, Julie A Fields, Ross R Reichard, Dennis W Dickson, Ronald C Petersen, Clifford R Jack, Val J Lowe, Jennifer L Whitwel. Optimum Differentiation of Frontotemporal Lobar Degeneration from Alzheimer Disease Achieved with Cross-Sectional Tau Positron Emission Tomography. Annals of neurology. 2022-09-02. PMID:36054427. optimum differentiation of frontotemporal lobar degeneration from alzheimer disease achieved with cross-sectional tau positron emission tomography. 2022-09-02 2023-08-14 Not clear