| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pengzhen Wang, Peng Yang, Kang Qian, Yixian Li, Shuting Xu, Ran Meng, Qian Guo, Yunlong Cheng, Jinxu Cao, Minjun Xu, Wei Lu, Qizhi Zhan. Precise gene delivery systems with detachable albumin shell remodeling dysfunctional microglia by TREM2 for treatment of Alzheimer's disease. Biomaterials. vol 281. 2022-01-06. PMID:34991033. |
precise gene delivery systems with detachable albumin shell remodeling dysfunctional microglia by trem2 for treatment of alzheimer's disease. |
2022-01-06 |
2023-08-13 |
mouse |
| Katherine E Prater, Kevin J Green, Kenneth L Chiou, Carole L Smith, Wei Sun, Ali Shojaie, Laura M Heath, Shannon Rose, C Dirk Keene, Benjamin A Logsdon, Noah Snyder-Mackler, Elizabeth E Blue, Jessica E Young, Gwenn A Garden, Suman Jayade. Microglia subtype transcriptomes differ between Alzheimer Disease and control human postmortem brain samples. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971137. |
microglia subtype transcriptomes differ between alzheimer disease and control human postmortem brain samples. |
2021-12-31 |
2023-08-13 |
human |
| LuLin Jiang, Xiaoguang Li, Stephanie Myers, Timothy Huang, Randal J Kaufma. Astroglial ER protein Membralin is an essential neuroinflammation regulator. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971195. |
glial cells, including astrocytes and microglia, are the immune cells in the brains, becoming reactive/gliosis during the progression of alzheimer's disease (ad). |
2021-12-31 |
2023-08-13 |
mouse |
| Paul M Kim, Michael D Kornber. Targeting PKC in microglia to promote remyelination and repair in the CNS. Current opinion in pharmacology. vol 62. 2021-12-29. PMID:34965482. |
microglia and cns-infiltrating macrophages play significant roles in the pathogenesis of neuroinflammatory and neurodegenerative diseases, such as alzheimer's disease, parkinson's disease, and multiple sclerosis. |
2021-12-29 |
2023-08-13 |
Not clear |
| Arthur A Vandenbark, Halina Offner, Szymon Matejuk, Agata Mateju. Microglia and astrocyte involvement in neurodegeneration and brain cancer. Journal of neuroinflammation. vol 18. issue 1. 2021-12-24. PMID:34949203. |
here, we discuss recent perspectives on the role of microglia and astrocytes in neurological disorders, including the two most common neurodegenerative conditions, alzheimer disease and progranulin-related frontotemporal lobar dementia, as well as astrocytoma brain tumors. |
2021-12-24 |
2023-08-13 |
Not clear |
| Seungmin Lee, In Gyoung Ju, Yujin Choi, Sangsu Park, Myung Sook O. Trichosanthis Semen Suppresses Lipopolysaccharide-Induced Neuroinflammation by Regulating the NF-κB Signaling Pathway and HO-1 Expression in Microglia. Toxins. vol 13. issue 12. 2021-12-23. PMID:34941735. |
neuroinflammation, which is mediated by microglia that release various inflammatory cytokines, is a typical feature of neurodegenerative diseases (ndds), such as alzheimer's disease and parkinson's disease. |
2021-12-23 |
2023-08-13 |
Not clear |
| Irene Frigerio, Baayla D C Boon, Chen-Pei Lin, Yvon Galis-de Graaf, John Bol, Paolo Preziosa, Jos Twisk, Frederik Barkhof, Jeroen J M Hoozemans, Femke H Bouwman, Annemieke J M Rozemuller, Wilma D J van de Berg, Laura E Jonkma. Amyloid-β, p-tau and reactive microglia are pathological correlates of MRI cortical atrophy in Alzheimer's disease. Brain communications. vol 3. issue 4. 2021-12-20. PMID:34927073. |
amyloid-β, p-tau and reactive microglia are pathological correlates of mri cortical atrophy in alzheimer's disease. |
2021-12-20 |
2023-08-13 |
Not clear |
| Étienne Gervais, Parisa Iloun, Ekaterina Martianova, Ana Claudia Gonçalves Bessa, Serge Rivest, Lisa Topolni. Structural analysis of the microglia-interneuron interactions in the CA1 hippocampal area of the APP/PS1 mouse model of Alzheimer's disease. The Journal of comparative neurology. 2021-12-17. PMID:34919273. |
here, we compared the interactions between microglia and parvalbumin (pv+) and somatostatin (som+) expressing interneurons in the ca1 hippocampal area of app/ps1 transgenic mice that mimic certain aspects of the alzheimer's disease (ad). |
2021-12-17 |
2023-08-13 |
mouse |
| Denisa Palova, Natalia Turic Csokova, Karina Markova, Eva Kontsekova, Branislav Kovacech, Monika Zilkov. The engagement of microglia in tau-targeted immunotherapy in Alzheimer's disease. General physiology and biophysics. vol 40. issue 6. 2021-12-13. PMID:34897021. |
the engagement of microglia in tau-targeted immunotherapy in alzheimer's disease. |
2021-12-13 |
2023-08-13 |
Not clear |
| Guimei Zhang, Zicheng Wang, Huiling Hu, Meng Zhao, Li Su. Microglia in Alzheimer's Disease: A Target for Therapeutic Intervention. Frontiers in cellular neuroscience. vol 15. 2021-12-13. PMID:34899188. |
microglia in alzheimer's disease: a target for therapeutic intervention. |
2021-12-13 |
2023-08-13 |
Not clear |
| Yiliang Wang, Weisheng Luo, Xiaohui Wang, Yuying Ma, Lianzhou Huang, Yifei Wan. MAMDC2, a gene highly expressed in microglia of AD mice, positively regulated the innate antiviral response upon neurotropic virus infection. The Journal of infection. 2021-12-13. PMID:34902449. |
microglia, as central nervous system (cns)-resident macrophages, are the first line of defense against neurotropic virus infection, the immune response of which is implicated in numerous cns diseases, including alzheimer's disease (ad). |
2021-12-13 |
2023-08-13 |
mouse |
| Caden M Henningfield, Miguel A Arreola, Neelakshi Soni, Elizabeth E Spangenberg, Kim N Gree. Microglia-specific ApoE knock-out does not alter Alzheimer's disease plaque pathogenesis or gene expression. Glia. vol 70. issue 2. 2021-12-10. PMID:34643971. |
previous studies suggest that microglial-expressed apolipoprotein e (apoe) is necessary to shift microglia into a neurodegenerative transcriptional state in alzheimer's disease (ad) mouse models. |
2021-12-10 |
2023-08-13 |
mouse |
| Amy M Smith, Karen Davey, Stergios Tsartsalis, Combiz Khozoie, Nurun Fancy, See Swee Tang, Eirini Liaptsi, Maria Weinert, Aisling McGarry, Robert C J Muirhead, Steve Gentleman, David R Owen, Paul M Matthew. Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology. Acta neuropathologica. 2021-12-08. PMID:34767070. |
to better define roles that astrocytes and microglia play in alzheimer's disease (ad), we used single-nuclei rna-sequencing to comprehensively characterise transcriptomes in astrocyte and microglia nuclei selectively enriched during isolation post-mortem from neuropathologically defined ad and control brains with a range of amyloid-beta and phospho-tau (ptau) pathology. |
2021-12-08 |
2023-08-13 |
human |
| Rishika Dhapola, Subhendu Shekhar Hota, Phulen Sarma, Anusuya Bhattacharyya, Bikash Medhi, Dibbanti HariKrishna Redd. Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer's disease. Inflammopharmacology. vol 29. issue 6. 2021-12-08. PMID:34813026. |
targeting these pathways and eventually ameliorating the activation of microglia can mitigate neuroinflammation and come out as a better therapeutic option for the treatment of alzheimer's disease. |
2021-12-08 |
2023-08-13 |
Not clear |
| Tyler K Ulland, Andrea C Ewald, Andrew O Knutson, Kaitlyn M Marino, Stephanie M C Smith, Jyoti J Watter. Alzheimer's Disease, Sleep Disordered Breathing, and Microglia: Puzzling out a Common Link. Cells. vol 10. issue 11. 2021-12-08. PMID:34831129. |
alzheimer's disease, sleep disordered breathing, and microglia: puzzling out a common link. |
2021-12-08 |
2023-08-13 |
mouse |
| Lucrezia Bruno, Simge Karagil, Almas Mahmood, Ahmed Elbediwy, Michael Stolinski, Francesca E Mackenzi. Mechanosensing and the Hippo Pathway in Microglia: A Potential Link to Alzheimer's Disease Pathogenesis? Cells. vol 10. issue 11. 2021-12-08. PMID:34831369. |
mechanosensing and the hippo pathway in microglia: a potential link to alzheimer's disease pathogenesis? |
2021-12-08 |
2023-08-13 |
Not clear |
| Lucrezia Bruno, Simge Karagil, Almas Mahmood, Ahmed Elbediwy, Michael Stolinski, Francesca E Mackenzi. Mechanosensing and the Hippo Pathway in Microglia: A Potential Link to Alzheimer's Disease Pathogenesis? Cells. vol 10. issue 11. 2021-12-08. PMID:34831369. |
the activation of microglia, the inflammatory cells of the central nervous system (cns), has been linked to the pathogenesis of alzheimer's disease and other neurodegenerative diseases. |
2021-12-08 |
2023-08-13 |
Not clear |
| Lucrezia Bruno, Simge Karagil, Almas Mahmood, Ahmed Elbediwy, Michael Stolinski, Francesca E Mackenzi. Mechanosensing and the Hippo Pathway in Microglia: A Potential Link to Alzheimer's Disease Pathogenesis? Cells. vol 10. issue 11. 2021-12-08. PMID:34831369. |
in this review, we examine evidence for the potential involvement of hippo pathway components specifically in microglia in the pathogenesis of alzheimer's disease. |
2021-12-08 |
2023-08-13 |
Not clear |
| Séverine Boillé. Local and remote interactions between macrophages and microglia in neurological conditions. Current opinion in immunology. vol 74. 2021-12-08. PMID:34864338. |
in neurodegenerative diseases such as alzheimer's disease or als, mdm mostly do not enter the cns, and instead microglia take several identities. |
2021-12-08 |
2023-08-13 |
Not clear |
| Chongdong Jian, Lei Wei, Ruikang Mo, Rongjie Li, Lucong Liang, Liechun Chen, Chun Zou, Youshi Meng, Ying Liu, Donghua Zo. Corrigendum: Microglia Mediate the Occurrence and Development of Alzheimer's Disease Through Ligand-Receptor Axis Communication. Frontiers in aging neuroscience. vol 13. 2021-12-07. PMID:34867308. |
corrigendum: microglia mediate the occurrence and development of alzheimer's disease through ligand-receptor axis communication. |
2021-12-07 |
2023-08-13 |
Not clear |