All Relations between Alzheimer Disease and microglial cell

Publication Sentence Publish Date Extraction Date Species
Yun Chen, Marco Colonn. Two-faced behavior of microglia in Alzheimer's disease. Nature neuroscience. 2021-11-24. PMID:34815557. two-faced behavior of microglia in alzheimer's disease. 2021-11-24 2023-08-13 Not clear
Wenwen Li, Shiyuan Wang, Heng Zhang, Bingqiu Li, Lingzhi Xu, Yan Li, Chaojun Kong, Haishan Jiao, Yan Wang, Yana Pang, Wei Qin, Longfei Jia, Jianping Ji. Honokiol Restores Microglial Phagocytosis by Reversing Metabolic Reprogramming. Journal of Alzheimer's disease : JAD. vol 82. issue 4. 2021-11-23. PMID:34151796. dysfunction of microglia has been increasingly recognized as a causative factor in alzheimer's disease (ad); thus, developing medicines capable of restoring microglial functions is critically important and constitutes a promising therapeutic strategy. 2021-11-23 2023-08-13 Not clear
Luisana Villegas, Anne Nørremølle, Kristine Freude, Frederik Vilhard. Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington's Disease? Frontiers in aging neuroscience. vol 13. 2021-11-23. PMID:34803655. relative to other neurodegenerative diseases such as alzheimer's and parkinson's disease and amyotrophic lateral sclerosis, where the effects of either microglia or nadph oxidases (noxs) are recognized as important contributors to disease pathogenesis and progression, there is a pronounced lack of information in hd. 2021-11-23 2023-08-13 human
Abhishek Bhattacherjee, Gour C Daskhan, Arjun Bains, Adrianne E S Watson, Ghazaleh Eskandari-Sedighi, Chris D St Laurent, Anastassia Voronova, Matthew S Macaule. Increasing phagocytosis of microglia by targeting CD33 with liposomes displaying glycan ligands. Journal of controlled release : official journal of the Controlled Release Society. vol 338. 2021-11-22. PMID:34517042. cd33 is an immunomodulatory receptor expressed by microglia and genetically linked to alzheimer's disease (ad) susceptibility. 2021-11-22 2023-08-13 mouse
Ping Sun, Hu Yue, Qi Xing, Wenmin Deng, Yitao Ou, Guangjin Pan, Xiaofen Zhong, Wenhui H. Compound AD16 Reduces Amyloid Plaque Deposition and Modifies Microglia in a Transgenic Mouse Model of Alzheimer's Disease. ACS pharmacology & translational science. vol 3. issue 6. 2021-11-19. PMID:33344892. compound ad16 reduces amyloid plaque deposition and modifies microglia in a transgenic mouse model of alzheimer's disease. 2021-11-19 2023-08-13 mouse
Qi Qin, Zhaoqian Teng, Changmei Liu, Qian Li, Yunsi Yin, Yi Tan. TREM2, microglia, and Alzheimer's disease. Mechanisms of ageing and development. vol 195. 2021-11-19. PMID:33516818. trem2, microglia, and alzheimer's disease. 2021-11-19 2023-08-13 Not clear
Boyd Kenkhuis, Antonios Somarakis, Lorraine de Haan, Oleh Dzyubachyk, Marieke E IJsselsteijn, Noel F C C de Miranda, Boudewijn P F Lelieveldt, Jouke Dijkstra, Willeke M C van Roon-Mom, Thomas Höllt, Louise van der Weer. Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33597025. iron loading is a prominent feature of activated microglia in alzheimer's disease patients. 2021-11-18 2023-08-13 human
Boyd Kenkhuis, Antonios Somarakis, Lorraine de Haan, Oleh Dzyubachyk, Marieke E IJsselsteijn, Noel F C C de Miranda, Boudewijn P F Lelieveldt, Jouke Dijkstra, Willeke M C van Roon-Mom, Thomas Höllt, Louise van der Weer. Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33597025. therefore, using histological methods, multispectral immunofluorescence and an automated in-house developed microglia segmentation and analysis pipeline, we studied the occurrence of iron-accumulating microglia and the effect on its activation state in human alzheimer brains. 2021-11-18 2023-08-13 human
Yiyi Ma, Lei Yu, Marta Olah, Rebecca Smith, Stephanie R Oatman, Mariet Allen, Ehsan Pishva, Bin Zhang, Vilas Menon, Nilüfer Ertekin-Taner, Katie Lunnon, David A Bennett, Hans-Ulrich Klein, Philip L De Jage. EPIGENOMIC FEATURES RELATED TO MICROGLIA ARE ASSOCIATED WITH ATTENUATED EFFECT OF APOE ε4 ON ALZHEIMER'S DISEASE RISK IN HUMANS. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 16. issue Suppl 2. 2021-11-18. PMID:34393677. epigenomic features related to microglia are associated with attenuated effect of apoe ε4 on alzheimer's disease risk in humans. 2021-11-18 2023-08-13 Not clear
Nofar Stolero, Dan Frenke. The dialog between neurons and microglia in Alzheimer's disease: The neurotransmitters view. Journal of neurochemistry. vol 158. issue 6. 2021-11-17. PMID:33314073. the dialog between neurons and microglia in alzheimer's disease: the neurotransmitters view. 2021-11-17 2023-08-13 Not clear
Natja Haag, Hans Zempe. Persistent astrocytic IL-3 stimulation of microglia slows disease in Alzheimer's: treatment perspectives for Alzheimer's. Signal transduction and targeted therapy. vol 6. issue 1. 2021-11-17. PMID:34753904. persistent astrocytic il-3 stimulation of microglia slows disease in alzheimer's: treatment perspectives for alzheimer's. 2021-11-17 2023-08-13 Not clear
Jannis Wißfeld, Ichiro Nozaki, Mona Mathews, Tamara Raschka, Christian Ebeling, Veit Hornung, Oliver Brüstle, Harald Neuman. Deletion of Alzheimer's disease-associated CD33 results in an inflammatory human microglia phenotype. Glia. vol 69. issue 6. 2021-11-16. PMID:33539598. deletion of alzheimer's disease-associated cd33 results in an inflammatory human microglia phenotype. 2021-11-16 2023-08-13 human
Emma Gerrits, Nieske Brouwer, Susanne M Kooistra, Maya E Woodbury, Yannick Vermeiren, Mirjam Lambourne, Jan Mulder, Markus Kummer, Thomas Möller, Knut Biber, Wilfred F A den Dunnen, Peter P De Deyn, Bart J L Eggen, Erik W G M Boddek. Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease. Acta neuropathologica. vol 141. issue 5. 2021-11-16. PMID:33609158. distinct amyloid-β and tau-associated microglia profiles in alzheimer's disease. 2021-11-16 2023-08-13 mouse
Prateep Amonruttanapun, Sukumal Chongthammakun, Siriporn Chamniansawa. The effects of okadaic acid-treated SH-SY5Y cells on microglia activation and phagocytosis. Cell biology international. 2021-11-16. PMID:34748253. the activation of microglia is found to be associated with neurodegenerative disorders including alzheimer's disease (ad). 2021-11-16 2023-08-13 Not clear
Mengmeng Wang, Yuanyuan Jiang, Zhihui Huan. Loss of C9orf72 in Microglia Drives Neuronal Injury by Enhancing Synaptic Pruning in Aged and Alzheimer's Disease Mice. Neuroscience bulletin. 2021-11-16. PMID:34783984. loss of c9orf72 in microglia drives neuronal injury by enhancing synaptic pruning in aged and alzheimer's disease mice. 2021-11-16 2023-08-13 mouse
Akira Sobue, Okiru Komine, Yuichiro Hara, Fumito Endo, Hiroyuki Mizoguchi, Seiji Watanabe, Shigeo Murayama, Takashi Saito, Takaomi C Saido, Naruhiko Sahara, Makoto Higuchi, Tomoo Ogi, Koji Yamanak. Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer's disease. Acta neuropathologica communications. vol 9. issue 1. 2021-11-15. PMID:33402227. microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of alzheimer's disease. 2021-11-15 2023-08-13 mouse
Miren Ettcheto, Amanda Cano, Elena Sanchez-López, Ester Verdaguer, Jaume Folch, Carme Auladell, Antoni Camin. Masitinib for the treatment of Alzheimer's disease. Neurodegenerative disease management. vol 11. issue 4. 2021-11-15. PMID:34412534. masitinib is a potent and selective phenylaminothiazole-type tyrosine kinase inhibitor which is currently in phase iii studies for the treatment of alzheimer's disease (ad) with the aim of modifying its evolution and with multiple pharmacological targets such as inhibition of mast cells activity, inhibition of microglia activation, modulation of aβ and tau protein signaling pathway and prevention of synaptic damage. 2021-11-15 2023-08-13 Not clear
Kazuyuki Takata, Florent Ginhoux, Shun Shimoham. Roles of microglia in Alzheimer's disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention. Biochemical pharmacology. vol 192. 2021-11-15. PMID:34480881. roles of microglia in alzheimer's disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention. 2021-11-15 2023-08-13 Not clear
Kazuyuki Takata, Florent Ginhoux, Shun Shimoham. Roles of microglia in Alzheimer's disease and impact of new findings on microglial heterogeneity as a target for therapeutic intervention. Biochemical pharmacology. vol 192. 2021-11-15. PMID:34480881. recent studies also revealed functions of microglia in neuroprotection and neuroinflammation, leading to the discovery that microglia are involved in several brain pathologies including alzheimer's disease (ad). 2021-11-15 2023-08-13 Not clear
Qingqing Li, Yingying Wu, Jichun Chen, Aiguo Xuan, Xiao Wan. Microglia and immunotherapy in Alzheimer's disease. Acta neurologica Scandinavica. 2021-11-15. PMID:34779509. microglia and immunotherapy in alzheimer's disease. 2021-11-15 2023-08-13 Not clear