All Relations between Alzheimer Disease and microglial cell

Publication Sentence Publish Date Extraction Date Species
Tingting Han, Yuxiang Xu, Lin Sun, Makoto Hashimoto, Jianshe We. Microglial response to aging and neuroinflammation in the development of neurodegenerative diseases. Neural regeneration research. vol 19. issue 6. 2023-10-31. PMID:37905870. this review describes the origin and function of microglia and focuses on the role of different states of the microglial response to aging and chronic inflammation on the occurrence and development of neurodegenerative diseases, including alzheimer's disease, huntington's chorea, and parkinson's disease. 2023-10-31 2023-11-08 Not clear
Abdollah Jafarzadeh, Abdolkarim Sheikhi, Zahra Jafarzadeh, Maryam Nemat. Differential roles of regulatory T cells in Alzheimer's disease. Cellular immunology. vol 393-394. 2023-10-31. PMID:37907046. extracellular amyloid-β (aβ) peptide deposition and secondary persistent inflammation due to activation of microglia, astrocytes, and infiltrated immune cells contribute to alzheimer's disease (ad)-related neurodegeneration. 2023-10-31 2023-11-08 Not clear
Jianguo Liu, Joseph R Geraghty, Sarah Schram, Haley C Cropper, Justin Lei, Jeffrey A Loeb, Fei Son. Prevention of Alzheimer pathology by blocking neuregulin signaling on microglia. eNeuro. 2023-10-30. PMID:37903620. prevention of alzheimer pathology by blocking neuregulin signaling on microglia. 2023-10-30 2023-11-08 mouse
Jianguo Liu, Joseph R Geraghty, Sarah Schram, Haley C Cropper, Justin Lei, Jeffrey A Loeb, Fei Son. Prevention of Alzheimer pathology by blocking neuregulin signaling on microglia. eNeuro. 2023-10-30. PMID:37903620. selective, targeted disruption of neuregulin-1 signaling on brain microglia with glyb4 could be a novel 'upstream' approach to slow or stop disease progression in alzheimer's disease. 2023-10-30 2023-11-08 mouse
Kenneth Maies. Microglia: Formidable Players in Alzheimer's Disease and Other Neurodegenerative Disorders. Current neurovascular research. 2023-10-27. PMID:37888824. microglia: formidable players in alzheimer's disease and other neurodegenerative disorders. 2023-10-27 2023-11-08 Not clear
Lee-Way Jin, Jacopo Di Lucente, Ulises Ruiz Mendiola, Nopparat Suthprasertporn, Alexey Tomilov, Gino Cortopassi, Kyoungmi Kim, Jon J Ramsey, Izumi Maezaw. The ketone body β-hydroxybutyrate shifts microglial metabolism and suppresses amyloid-β oligomer-induced inflammation in human microglia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 11. 2023-10-26. PMID:37878335. we investigated the impact of bhb on aβ oligomer (aβo)-stimulated human ips-derived microglia (himg), a model relevant to the pathogenesis of alzheimer's disease (ad). 2023-10-26 2023-11-08 human
Gijsje J L J Snijders, Katia de Paiva Lopes, Marjolein A M Sneeboer, Benjamin Z Muller, Frederieke A J Gigase, Ricardo A Vialle, Roy Missall, Raphael Kubler, Towfique Raj, Jack Humphrey, Lot D de Witt. The human microglia responsome: a resource to better understand microglia states in health and disease. bioRxiv : the preprint server for biology. 2023-10-24. PMID:37873223. finally, we used our stimulation signatures to interpret associations from alzheimer's disease (ad) genetic studies and microglia by integrating our inflammatory gene expression profiles with common genetic variants to map 2023-10-24 2023-11-08 mouse
Hiroshi Ikenuma, Aya Ogata, Hiroko Koyama, Bin Ji, Hideki Ishii, Takashi Yamada, Junichiro Abe, Chie Seki, Yuji Nagai, Masanori Ichise, Takafumi Minamimoto, Makoto Higuchi, Ming-Rong Zhang, Takashi Kato, Kengo Ito, Masaaki Suzuki, Yasuyuki Kimur. Synthesis and evaluation of a novel PET ligand, a GSK'963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain. EJNMMI radiopharmacy and chemistry. vol 8. issue 1. 2023-10-20. PMID:37853253. recently, the involvement of ripk1 in the pathophysiology of alzheimer's disease (ad) has been reported; ripk1 is involved in microglia's phenotypic transition to their dysfunctional states, and it is highly expressed in the neurons and microglia in the postmortem brains in ad patients. 2023-10-20 2023-11-08 Not clear
Kai Schlepckow, Estrella Morenas-Rodríguez, Soyon Hong, Christian Haas. Stimulation of TREM2 with agonistic antibodies-an emerging therapeutic option for Alzheimer's disease. The Lancet. Neurology. vol 22. issue 11. 2023-10-20. PMID:37863592. microglia have long been considered to have detrimental roles in alzheimer's disease. 2023-10-20 2023-11-08 Not clear
Kai Schlepckow, Estrella Morenas-Rodríguez, Soyon Hong, Christian Haas. Stimulation of TREM2 with agonistic antibodies-an emerging therapeutic option for Alzheimer's disease. The Lancet. Neurology. vol 22. issue 11. 2023-10-20. PMID:37863592. however, functional analyses of genes encoding risk factors that are linked to late-onset alzheimer's disease, and that are enriched or exclusively expressed in microglia, have revealed unexpected protective functions. 2023-10-20 2023-11-08 Not clear
Ianis Kevyn Stefan Boboc, Alexandru Cojocaru, Gabriel Nedelea, Bogdan Catalin, Maria Bogdan, Daniela Calin. Chronic Administration of Ion Channel Blockers Impact Microglia Morphology and Function in a Murine Model of Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37833922. chronic administration of ion channel blockers impact microglia morphology and function in a murine model of alzheimer's disease. 2023-10-14 2023-10-15 mouse
Ianis Kevyn Stefan Boboc, Alexandru Cojocaru, Gabriel Nedelea, Bogdan Catalin, Maria Bogdan, Daniela Calin. Chronic Administration of Ion Channel Blockers Impact Microglia Morphology and Function in a Murine Model of Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37833922. with microglia's important involvement in the pathology and progression of alzheimer's disease (ad), understanding whether systemically administered drugs intended for other affections could impact microglia function, already impacted by the presence of beta-amyloid, is important. 2023-10-14 2023-10-15 mouse
Flavia Scoyni, Luca Giudice, Mari-Anna Väänänen, Nicholas Downes, Paula Korhonen, Xin Yi Choo, Nelli-Noora Välimäki, Petri Mäkinen, Nea Korvenlaita, Annemieke J Rozemuller, Helga E de Vries, Jose Polo, Tiia A Turunen, Seppo Ylä-Herttuala, Thomas B Hansen, Alexandra Grubman, Minna U Kaikkonen, Tarja Mal. Alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-10-13. PMID:37828821. alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding rnas. 2023-10-13 2023-10-15 Not clear
Joshua D Samuels, John R Lukens, Richard J Pric. Emerging roles for ITAM and ITIM receptor signaling in microglial biology and Alzheimer's disease-related amyloidosis. Journal of neurochemistry. 2023-10-12. PMID:37822118. microglia are critical responders to amyloid beta (aβ) plaques in alzheimer's disease (ad). 2023-10-12 2023-10-15 Not clear
Qianting Deng, Chongyun Wu, Emily Parker, Timon Cheng-Yi Liu, Rui Duan, Luodan Yan. Microglia and Astrocytes in Alzheimer's Disease: Significance and Summary of Recent Advances. Aging and disease. 2023-10-10. PMID:37815901. microglia and astrocytes in alzheimer's disease: significance and summary of recent advances. 2023-10-10 2023-10-15 Not clear
Raquel N Taddei, Romain Perbet, Anastasie Mate de Gerando, Anne E Wiedmer, Maria Sanchez-Mico, Theresa Connors Stewart, Angelica Gaona, Alexandra Melloni, Ana C Amaral, Karen Duff, Matthew P Frosch, Teresa Gómez-Isl. Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease. JAMA neurology. 2023-10-09. PMID:37812432. tau oligomer-containing synapse elimination by microglia and astrocytes in alzheimer disease. 2023-10-09 2023-10-15 Not clear
Miao Zhang, Xiao-Hang Qian, Jialin Hu, Yaoyu Zhang, Xiaozhu Lin, Wangxi Hai, Kuangyu Shi, Xufeng Jiang, Yao Li, Hui-Dong Tang, Biao L. Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid-β deposition in Alzheimer's disease. European journal of nuclear medicine and molecular imaging. 2023-10-06. PMID:37801139. despite the revealed role of immunological dysfunctions in the development and progression of alzheimer's disease (ad) through animal and postmortem investigations, direct evidence regarding the impact of genetic factors on microglia response and amyloid-β (aβ) deposition in ad individuals is lacking. 2023-10-06 2023-10-07 Not clear
Yi-Huan Guan, Ling-Jing Zhang, Shi-Ya Wang, Ya-Dan Deng, Hong-Su Zhou, Dong-Qing Chen, Lan-Chun Zhan. The role of microglia in Alzheimer's disease and progress of treatment. Ibrain. vol 8. issue 1. 2023-10-03. PMID:37786418. the role of microglia in alzheimer's disease and progress of treatment. 2023-10-03 2023-10-07 Not clear
Yi-Huan Guan, Ling-Jing Zhang, Shi-Ya Wang, Ya-Dan Deng, Hong-Su Zhou, Dong-Qing Chen, Lan-Chun Zhan. The role of microglia in Alzheimer's disease and progress of treatment. Ibrain. vol 8. issue 1. 2023-10-03. PMID:37786418. microglia play an important role in the pathological process of alzheimer's disease (ad). 2023-10-03 2023-10-07 Not clear
Qiu-Lin Wang, Chang-Le Fang, Xue-Yan Huang, Lu-Lu Xu. Research progress of the CXCR4 mechanism in Alzheimer's disease. Ibrain. vol 8. issue 1. 2023-10-03. PMID:37786419. alzheimer's disease (ad) is a degenerative brain disease with complex clinical manifestations and pathogeneses such as abnormal deposition of beta-amyloid protein and inflammation caused by the excessive activation of microglia. 2023-10-03 2023-10-07 Not clear