All Relations between Alzheimer Disease and microglial cell

Publication Sentence Publish Date Extraction Date Species
Alexander Kellner, Jakob Matschke, Christian Bernreuther, Holger Moch, Isidro Ferrer, Markus Glatze. Autoantibodies against beta-amyloid are common in Alzheimer's disease and help control plaque burden. Annals of neurology. vol 65. issue 1. 2009-04-09. PMID:19194878. active or passive immunization of alzheimer's disease (ad) patients leads to targeting of beta-amyloid plaques by immunoglobulins (igg) and their subsequent removal by microglia. 2009-04-09 2023-08-12 Not clear
Douglas G Walker, Jessica E Dalsing-Hernandez, Nicole A Campbell, Lih-Fen Lu. Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: a potential mechanism leading to chronic inflammation. Experimental neurology. vol 215. issue 1. 2009-04-08. PMID:18938162. inflammatory activation of microglia in response to neurodegenerative changes in diseases such as alzheimer's disease (ad) and parkinson's disease has been extensively described. 2009-04-08 2023-08-12 human
A Okello, P Edison, H A Archer, F E Turkheimer, J Kennedy, R Bullock, Z Walker, A Kennedy, N Fox, M Rossor, D J Brook. Microglial activation and amyloid deposition in mild cognitive impairment: a PET study. Neurology. vol 72. issue 1. 2009-04-08. PMID:19122031. activated microglia may play a role in the pathogenesis of alzheimer disease (ad) as they cluster around beta-amyloid (abeta) plaques. 2009-04-08 2023-08-12 Not clear
Antero Salminen, Johanna Ojala, Tiina Suuronen, Kai Kaarniranta, Anu Kauppine. Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology. Journal of cellular and molecular medicine. vol 12. issue 6A. 2009-04-02. PMID:18793350. we will review here the activation mechanisms of nalp inflammasomes in neurons and microglia and several downstream effects in brain demonstrating that toxic amyloid-beta oligomers and fibrils can light afire in inflammasomes and induce alzheimer's pathology. 2009-04-02 2023-08-12 mouse
Uzma A Chaudhry, Sylvain Dor. Cytosolic prostaglandin E synthase: expression patterns in control and Alzheimer's disease brains. American journal of Alzheimer's disease and other dementias. vol 24. issue 1. 2009-04-01. PMID:19001348. these findings revealed that cytosolic prostaglandin e(2) synthases is found in microglia, neurons, and endothelium of control human middle frontal gyrus and that its levels decrease in pyramidal cells of alzheimer's disease brains. 2009-04-01 2023-08-12 human
Jong Kil Lee, Hee Kyung Jin, Jae-Sung Ba. Bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model. Neuroscience letters. vol 450. issue 2. 2009-03-24. PMID:19084047. bone marrow-derived mesenchymal stem cells reduce brain amyloid-beta deposition and accelerate the activation of microglia in an acutely induced alzheimer's disease mouse model. 2009-03-24 2023-08-12 mouse
b' Johanna O Ojala, Elina M Sutinen, Antero Salminen, Tuula Pirttil\\xc3\\xa. Interleukin-18 increases expression of kinases involved in tau phosphorylation in SH-SY5Y neuroblastoma cells. Journal of neuroimmunology. vol 205. issue 1-2. 2009-03-19. PMID:18947885.' inflammatory cytokines, produced mainly by activated microglia in the brain, can enhance neuronal degeneration and the amyloid-beta-plaque production involved in alzheimer's disease (ad). 2009-03-19 2023-08-12 Not clear
Jian Jiao, Bing Xue, Lei Zhang, Yuntao Gong, Kairong Li, Haomin Wang, Liming Jing, Junxia Xie, Xiaomin Wan. Triptolide inhibits amyloid-beta1-42-induced TNF-alpha and IL-1beta production in cultured rat microglia. Journal of neuroimmunology. vol 205. issue 1-2. 2009-03-19. PMID:19004508. microglia plays an important role in mediating neuroinflammation in alzheimer's disease (ad). 2009-03-19 2023-08-12 rat
Paul Edison, Hilary A Archer, Alexander Gerhard, Rainer Hinz, Nicola Pavese, Federico E Turkheimer, Alexander Hammers, Yen Fong Tai, Nick Fox, Angus Kennedy, Martin Rossor, David J Brook. Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study. Neurobiology of disease. vol 32. issue 3. 2009-01-28. PMID:18786637. microglia, amyloid, and cognition in alzheimer's disease: an [11c](r)pk11195-pet and [11c]pib-pet study. 2009-01-28 2023-08-12 human
Eisuke Shimizu, Kohichi Kawahara, Makoto Kajizono, Makoto Sawada, Hitoshi Nakayam. IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 9. 2009-01-21. PMID:18941241. a hallmark of immunopathology associated with alzheimer's disease is the presence of activated microglia (mg) surrounding senile plaque deposition of beta-amyloid (abeta) peptides. 2009-01-21 2023-08-12 rat
Hitoshi Nakayam. [Seeking "Etwas Neues"--from bioorganic chemistry to Alzheimer's disease]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 128. issue 11. 2009-01-14. PMID:18981699. in microglia, however, cd36 plays clearance role of oligomeric beta-amyloid peptides in il-4 activated type-2 microglia, suggesting the activation of type-2 microglia may be useful for developing a new method to treat or prevent from alzheimer's disease. 2009-01-14 2023-08-12 Not clear
Margot Egger, Arno G E Beer, Markus Theurl, Wilfried Schgoer, Benjamin Hotter, Tobias Tatarczyk, Danijela Vasiljevic, Silke Frauscher, Josef Marksteiner, Josef R Patsch, Peter Schratzberger, Angela M Djanani, Sushil K Mahata, Rudolf Kirchmai. Monocyte migration: a novel effect and signaling pathways of catestatin. European journal of pharmacology. vol 598. issue 1-3. 2009-01-09. PMID:18834877. furthermore, chromogranin a (cga) containing alzheimer plaques are characterized by extensive microglia activation and such activation induces neuronal damage. 2009-01-09 2023-08-12 human
F Cortini, C Fenoglio, I Guidi, E Venturelli, S Pomati, A Marcone, D Scalabrini, C Villa, F Clerici, E Dalla Valle, C Mariani, S Cappa, N Bresolin, E Scarpini, D Galimbert. Novel exon 1 progranulin gene variant in Alzheimer's disease. European journal of neurology. vol 15. issue 10. 2009-01-05. PMID:18752597. progranulin (pgrn) expression is increased in activated microglia in alzheimer's disease (ad) brain, suggesting a potential role in this pathology. 2009-01-05 2023-08-12 Not clear
Rosemary H Milton, Rosella Abeti, Stefania Averaimo, Silvia DeBiasi, Laura Vitellaro, Lele Jiang, Paul M G Curmi, Samuel N Breit, Michael R Duchen, Michele Mazzant. CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 45. 2008-12-31. PMID:18987185. the alzheimer's disease (ad) brain is characterized by plaques containing beta-amyloid (abeta) protein surrounded by astrocytes and reactive microglia. 2008-12-31 2023-08-12 Not clear
Ji-Young Park, Seung R Paik, Ilo Jou, Sang Myun Par. Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinson's disease. Glia. vol 56. issue 11. 2008-12-18. PMID:18449945. gathering evidence has associated activation of microglia with the pathogenesis of numerous neurodegenerative diseases of the central nervous system (cns) such as alzheimer's disease and parkinson's disease. 2008-12-18 2023-08-12 Not clear
Malabendu Jana, Carlos A Palencia, Kalipada Paha. Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 10. 2008-12-12. PMID:18981147. fibrillar amyloid-beta peptides activate microglia via tlr2: implications for alzheimer's disease. 2008-12-12 2023-08-12 mouse
Jaegyu Hwang, Long Tai Zheng, Jiyeon Ock, Maan Gee Lee, Kyoungho Su. Anti-inflammatory effects of m-chlorophenylpiperazine in brain glia cells. International immunopharmacology. vol 8. issue 12. 2008-12-03. PMID:18771755. microglia and astrocytes have been reported to play an important role in the progression of neurodegenerative diseases such as alzheimer's disease and parkinson's disease. 2008-12-03 2023-08-12 Not clear
Elisabetta Vegeto, Valeria Benedusi, Adriana Magg. Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases. Frontiers in neuroendocrinology. vol 29. issue 4. 2008-11-18. PMID:18522863. the neurodegenerative process of several cns diseases, including multiple sclerosis, alzheimer's and parkinson's diseases, is associated with the activation of microglia cells, which drive the resident inflammatory response. 2008-11-18 2023-08-12 Not clear
Elena Avignone, Lauriane Ulmann, Françoise Levavasseur, François Rassendren, Etienne Audina. Status epilepticus induces a particular microglial activation state characterized by enhanced purinergic signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 37. 2008-11-03. PMID:18784294. microglia cells are the resident macrophages of the cns, and their activation plays a critical role in inflammatory reactions associated with many brain disorders, including ischemia, alzheimer's and parkinson's diseases, and epilepsy. 2008-11-03 2023-08-12 mouse
Jun Liu, Zhen Hong, Jianqing Ding, Jianrong Liu, Jing Zhang, Shengdi Che. Predominant release of lysosomal enzymes by newborn rat microglia after LPS treatment revealed by proteomic studies. Journal of proteome research. vol 7. issue 5. 2008-09-22. PMID:18380473. growing evidence suggest that microglia may play an important role in the pathogenesis of neurodegenerative disease including parkinson's disease, alzheimer's disease, and so forth. 2008-09-22 2023-08-12 rat