All Relations between Alzheimer Disease and microglial cell

Publication Sentence Publish Date Extraction Date Species
Eliza Lewandowska, Teresa Wierzba-Bobrowicz, Elzbieta Kosno-Kruszewska, Waldemar Lechowicz, Bogna Schmidt-Sidor, Grazyna M Szpak, Ewa Bertrand, Elzbieta Pasennik, Elzbieta Gwiazd. Ultrastructural evaluation of activated forms of microglia in human brain in selected neurological diseases (SSPE, Wilson's disease and Alzheimer's disease). Folia neuropathologica. vol 42. issue 2. 2004-08-24. PMID:15266782. ultrastructural evaluation of activated forms of microglia in human brain in selected neurological diseases (sspe, wilson's disease and alzheimer's disease). 2004-08-24 2023-08-12 human
Eliza Lewandowska, Teresa Wierzba-Bobrowicz, Elzbieta Kosno-Kruszewska, Waldemar Lechowicz, Bogna Schmidt-Sidor, Grazyna M Szpak, Ewa Bertrand, Elzbieta Pasennik, Elzbieta Gwiazd. Ultrastructural evaluation of activated forms of microglia in human brain in selected neurological diseases (SSPE, Wilson's disease and Alzheimer's disease). Folia neuropathologica. vol 42. issue 2. 2004-08-24. PMID:15266782. activated forms of microglia were ultrastructurally evaluated in three neurological diseases of different aetiology (subacute sclerosing panencephalitis--sspe, wilson's disease and alzheimer's disease). 2004-08-24 2023-08-12 human
Eliza Lewandowska, Teresa Wierzba-Bobrowicz, Elzbieta Kosno-Kruszewska, Waldemar Lechowicz, Bogna Schmidt-Sidor, Grazyna M Szpak, Ewa Bertrand, Elzbieta Pasennik, Elzbieta Gwiazd. Ultrastructural evaluation of activated forms of microglia in human brain in selected neurological diseases (SSPE, Wilson's disease and Alzheimer's disease). Folia neuropathologica. vol 42. issue 2. 2004-08-24. PMID:15266782. in alzheimer's disease, activated microglia was most frequently bound to senile plaques. 2004-08-24 2023-08-12 human
Robert G Nagele, Jerzy Wegiel, Venkat Venkataraman, Humi Imaki, Kuo-Chiang Wang, Jarek Wegie. Contribution of glial cells to the development of amyloid plaques in Alzheimer's disease. Neurobiology of aging. vol 25. issue 5. 2004-08-23. PMID:15172746. amyloid plaques appear early during alzheimer's disease (ad), and their development is intimately linked to activated astrocytes and microglia. 2004-08-23 2023-08-12 Not clear
Onofre Combarros, Jon Infante, Javier Llorca, José Bercian. No evidence for association of the monocyte chemoattractant protein-1 (-2518) gene polymorphism and Alzheimer's disease. Neuroscience letters. vol 360. issue 1-2. 2004-06-04. PMID:15082170. activation of microglia is a central part of the chronic inflammatory process in alzheimer disease (ad). 2004-06-04 2023-08-12 human
P Eikelenboom, W A van Goo. Neuroinflammatory perspectives on the two faces of Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 3. 2004-06-01. PMID:14991455. the amyloid plaques in alzheimer's disease (ad) brains are co-localized with a broad variety of inflammation-related proteins (complement factors, acute-phase proteins, pro-inflammatory cytokines) and clusters of activated microglia. 2004-06-01 2023-08-12 Not clear
Toshiki Uchihara, Ayako Nakamura, Tetsuaki Arai, Kenji Ikeda, Kuniaki Tsuchiy. Microglial tau undergoes phosphorylation-independent modification after ischemia. Glia. vol 45. issue 2. 2004-04-30. PMID:14730711. tau2 is a phosphorylation-independent antibody that immunolabels neurofibrillary tangles (nfts) of alzheimer type and microglia around ischemic foci on formalin-fixed, paraffin-embedded sections. 2004-04-30 2023-08-12 human
Chandramohan Natarajan, Subramaniam Sriram, Gladson Muthian, John J Brigh. Signaling through JAK2-STAT5 pathway is essential for IL-3-induced activation of microglia. Glia. vol 45. issue 2. 2004-04-30. PMID:14730712. activation of microglia and secretion of inflammatory cytokines associate with the pathogenesis of cns diseases, including multiple sclerosis (ms), alzheimer's disease (ad), parkinson's disease, prion disease, and aids dementia. 2004-04-30 2023-08-12 Not clear
J Rofina, I van Andel, A M van Ederen, N Papaioannou, H Yamaguchi, Erik Gruy. Canine counterpart of senile dementia of the Alzheimer type: amyloid plaques near capillaries but lack of spatial relationship with activated microglia and macrophages. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 10. issue 2. 2004-04-19. PMID:12964416. canine counterpart of senile dementia of the alzheimer type: amyloid plaques near capillaries but lack of spatial relationship with activated microglia and macrophages. 2004-04-19 2023-08-12 human
Li Gan, Shiming Ye, Alan Chu, Kristin Anton, Saili Yi, Valerie A Vincent, David von Schack, Daniel Chin, Joseph Murray, Scott Lohr, Laszlo Patthy, Mirella Gonzalez-Zulueta, Karoly Nikolich, Roman Urfe. Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach. The Journal of biological chemistry. vol 279. issue 7. 2004-03-30. PMID:14612454. activated microglia are found to be intimately associated with senile plaques and may play a central role in mediating chronic inflammatory conditions in alzheimer's disease. 2004-03-30 2023-08-12 Not clear
David Rampe, Lin Wang, Garth E Ringhei. P2X7 receptor modulation of beta-amyloid- and LPS-induced cytokine secretion from human macrophages and microglia. Journal of neuroimmunology. vol 147. issue 1-2. 2004-03-15. PMID:14741428. to test whether extracellular atp can play a role in the neuroimmunopathology of alzheimer's disease (ad), we evaluated the capacity of the atp-binding purinoreceptor, p2x7, to modulate cytokine secretion on cultured human macrophages and microglia pre-activated 24 h with the 42 amino acid beta-amyloid peptide (abeta(1-42)) or lipopolysaccharide. 2004-03-15 2023-08-12 human
Yoshihisa Kitamura, Keiichi Shibagaki, Kazuyuki Takata, Daiju Tsuchiya, Takashi Taniguchi, Peter J Gebicke-Haerter, Hiroaki Miki, Tadaomi Takenawa, Shun Shimoham. Involvement of Wiskott-Aldrich syndrome protein family verprolin-homologous protein (WAVE) and Rac1 in the phagocytosis of amyloid-beta(1-42) in rat microglia. Journal of pharmacological sciences. vol 92. issue 2. 2004-03-09. PMID:12832839. alzheimer's disease (ad) is characterized by the accumulation of extracellular amyloid-beta (a beta) fibrils with microglia. 2004-03-09 2023-08-12 rat
Kazuyuki Takata, Yoshihisa Kitamura, Masaaki Umeki, Daiju Tsuchiya, Jun-ichi Kakimura, Takashi Taniguchi, Peter J Gebicke-Haerter, Shun Shimoham. Possible involvement of small oligomers of amyloid-beta peptides in 15-deoxy-delta 12,14 prostaglandin J2-sensitive microglial activation. Journal of pharmacological sciences. vol 91. issue 4. 2004-03-01. PMID:12719662. in alzheimer's disease, fibrillar amyloid-beta (abeta) peptides form senile plaques associated with microglia. 2004-03-01 2023-08-12 Not clear
Lisa M Melton, Alexander B Keith, Sue Davis, Arthur E Oakley, James A Edwardson, Christopher M Morri. Chronic glial activation, neurodegeneration, and APP immunoreactive deposits following acute administration of double-stranded RNA. Glia. vol 44. issue 1. 2003-12-15. PMID:12951652. several neurodegenerative disorders, including alzheimer's and parkinson's diseases, are associated with immunocompetent microglia, leading to the suggestion that chronic glial-mediated inflammation contributes to the neurodegeneration seen in these diseases. 2003-12-15 2023-08-12 human
Alon Monsonego, Jaime Imitola, Victor Zota, Takatoku Oida, Howard L Weine. Microglia-mediated nitric oxide cytotoxicity of T cells following amyloid beta-peptide presentation to Th1 cells. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 5. 2003-11-17. PMID:12928365. our results demonstrate no-dependent apoptosis of t cells by abeta-stimulated microglia which may enhance cns innate immune responses and neurotoxicity in alzheimer's disease. 2003-11-17 2023-08-12 Not clear
Mario Delgado, Doina Gane. Vasoactive intestinal peptide prevents activated microglia-induced neurodegeneration under inflammatory conditions: potential therapeutic role in brain trauma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 13. 2003-11-12. PMID:12923064. in most neurodegenerative disorders, including multiple sclerosis, parkinson's disease, and alzheimer's disease, a massive neuronal cell death occurs as a consequence of an uncontrolled inflammatory response, where activated microglia and its cytotoxic agents play a crucial pathologic role. 2003-11-12 2023-08-12 Not clear
Olivera M Mitrasinovic, Greer M Murph. Microglial overexpression of the M-CSF receptor augments phagocytosis of opsonized Abeta. Neurobiology of aging. vol 24. issue 6. 2003-10-29. PMID:12927763. the role of microglia in alzheimer's disease (ad) has come under intense scrutiny recently because microglia may clear amyloid beta (abeta) by phagocytosis after immunization of transgenic mice. 2003-10-29 2023-08-12 mouse
Richard C Dodel, Harald Hampel, Yansheng D. Immunotherapy for Alzheimer's disease. The Lancet. Neurology. vol 2. issue 4. 2003-08-27. PMID:12849209. recent studies in murine models of alzheimer's disease (ad) have found that active immunisation with amyloid-beta peptide (abeta) or passive immunisation with abeta antibodies can lessen the severity of abeta-induced neuritic plaque pathology through the activation of microglia. 2003-08-27 2023-08-12 Not clear
Magdalena Luca, Alexandra Chavez-Ross, Leah Edelstein-Keshet, Alex Mogilne. Chemotactic signaling, microglia, and Alzheimer's disease senile plaques: is there a connection? Bulletin of mathematical biology. vol 65. issue 4. 2003-08-21. PMID:12875339. chemotactic signaling, microglia, and alzheimer's disease senile plaques: is there a connection? 2003-08-21 2023-08-12 Not clear
Magdalena Luca, Alexandra Chavez-Ross, Leah Edelstein-Keshet, Alex Mogilne. Chemotactic signaling, microglia, and Alzheimer's disease senile plaques: is there a connection? Bulletin of mathematical biology. vol 65. issue 4. 2003-08-21. PMID:12875339. chemotactic cells known as microglia are involved in the inflammation associated with pathology in alzheimer's disease (ad). 2003-08-21 2023-08-12 Not clear