| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jaime Eugenín, Andrea Vecchiola, Paola Murgas, Pablo Arroyo, Francisca Cornejo, Rommy von Bernhard. Expression Pattern of Scavenger Receptors and Amyloid-β Phagocytosis of Astrocytes and Microglia in Culture are Modified by Acidosis: Implications for Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 53. issue 3. 2018-01-26. PMID:27258416. |
the pathological hallmarks of alzheimer's disease (ad) are amyloid-β (aβ) plaques, neurofibrillary tangles, and glia activation. |
2018-01-26 |
2023-08-13 |
Not clear |
| Bryn Farnsworth, Christiane Peuckert, Bettina Zimmermann, Elena Jazin, Petronella Kettunen, Lina Sors Emilsso. Gene Expression of Quaking in Sporadic Alzheimer's Disease Patients is Both Upregulated and Related to Expression Levels of Genes Involved in Amyloid Plaque and Neurofibrillary Tangle Formation. Journal of Alzheimer's disease : JAD. vol 53. issue 1. 2018-01-24. PMID:27163826. |
qki has previously been implicated in various neurological disorders and diseases, including alzheimer's disease (ad), a condition for which increasing evidence suggests a central role of glia cells. |
2018-01-24 |
2023-08-13 |
human |
| Francesca Boscia, Gulnaz Begum, Giuseppe Pignataro, Rossana Sirabella, Ornella Cuomo, Antonella Casamassa, Dandan Sun, Lucio Annunziat. Glial Na(+) -dependent ion transporters in pathophysiological conditions. Glia. vol 64. issue 10. 2018-01-02. PMID:27458821. |
in this review, we first briefly introduced the emerging roles of each glial cell type in the pathophysiology of cerebral ischemia, alzheimer's disease, epilepsy, parkinson's disease, amyotrophic lateral sclerosis, and myelin diseases. |
2018-01-02 |
2023-08-13 |
Not clear |
| Mortimer Mamela. Energy and the Alzheimer brain. Neuroscience and biobehavioral reviews. vol 75. 2017-10-24. PMID:28193453. |
however, pathology engages all of the major elements of the neurovascular unit of the mature alzheimer brain, the neurons, glia and blood vessels. |
2017-10-24 |
2023-08-13 |
mouse |
| Sultan Darves. Butyrylcholinesterase as a Diagnostic and Therapeutic Target for Alzheimer's Disease. Current Alzheimer research. vol 13. issue 10. 2017-10-02. PMID:27040140. |
in the human brain bche is mainly expressed in white matter and glia and in distinct populations of neurons in regions that are important in cognition and behavior, functions compromised in alzheimer's disease (ad). |
2017-10-02 |
2023-08-13 |
mouse |
| Mahesh Ramalingam, Sung-Jin Ki. Protective effects of activated signaling pathways by insulin on C6 glial cell model of MPP Journal of receptor and signal transduction research. vol 37. issue 1. 2017-04-25. PMID:27137951. |
protective effects of activated signaling pathways by insulin on c6 glial cell model of mpp parkinson's disease (pd) is the second most common neurodegenerative disorder after alzheimer's disease (ad) associated with mitochondrial dysfunction mediated by oxidative stress. |
2017-04-25 |
2023-08-13 |
Not clear |
| Erik N T P Bakker, Brian J Bacskai, Michal Arbel-Ornath, Roxana Aldea, Beatrice Bedussi, Alan W J Morris, Roy O Weller, Roxana O Carar. Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases. Cellular and molecular neurobiology. vol 36. issue 2. 2017-02-06. PMID:26993512. |
the presence of aβ in the glia limitans in alzheimer's disease suggests a direct communication of isf with csf. |
2017-02-06 |
2023-08-13 |
human |
| José J Rodríguez, Arthur M Butt, Emanuela Gardenal, Vladimir Parpura, Alexei Verkhratsk. Complex and differential glial responses in Alzheimer's disease and ageing. Current Alzheimer research. vol 13. issue 4. 2016-12-15. PMID:26923267. |
in this review, we provide a concise account of recent data obtained from both human material and animal models demonstrating the pathological involvement of glia in neurodegenerative processes, including alzheimer's disease (ad), as well as physiological ageing. |
2016-12-15 |
2023-08-13 |
human |
| Michael Maes, George Anderso. Overlapping the Tryptophan Catabolite (TRYCAT) and Melatoninergic Pathways in Alzheimer's Disease. Current pharmaceutical design. vol 22. issue 8. 2016-12-13. PMID:25547097. |
such trycats have significant impacts on neuronal functioning and survival contributing to the changes seen in alzheimer's disease (ad), including in its association with depression as well as alterations in the reactivity of immune and glia cells. |
2016-12-13 |
2023-08-13 |
Not clear |
| Jing Wang, Michael F Jackson, Yu-Feng Xi. Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer's Diseases. Neural plasticity. vol 2016. 2016-12-13. PMID:26942016. |
glia and trpm2 channels in plasticity of central nervous system and alzheimer's diseases. |
2016-12-13 |
2023-08-13 |
Not clear |
| Katie J Herbst-Robinson, Li Liu, Michael James, Yuemang Yao, Sharon X Xie, Kurt R Brunde. Inflammatory Eicosanoids Increase Amyloid Precursor Protein Expression via Activation of Multiple Neuronal Receptors. Scientific reports. vol 5. 2016-10-31. PMID:26672557. |
senile plaques comprised of aβ peptides are a hallmark of alzheimer's disease (ad) brain, as are activated glia that release inflammatory molecules, including eicosanoids. |
2016-10-31 |
2023-08-13 |
mouse |
| Silvia Fossati, Patrizia Giannoni, Maria E Solesio, Sarah L Cocklin, Erwin Cabrera, Jorge Ghiso, Agueda Rostagn. The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain. Neurobiology of disease. vol 86. 2016-10-14. PMID:26581638. |
here, using neuronal and glial cell cultures, in addition to an acute model of amyloid beta (aβ) toxicity, which replicates by intra-hippocampal injection the consequences of interstitial and cellular accumulation of aβ, we analyzed the effects of mtz on neuronal and glial degeneration induced by the alzheimer's amyloid. |
2016-10-14 |
2023-08-13 |
mouse |
| Hesham Montassir, Yoshihiro Maegaki, Kei Murayama, Taro Yamazaki, Masakazu Kohda, Akira Ohtake, Hiroyasu Iwasa, Yukiko Yatsuka, Yasushi Okazaki, Chitose Sugiura, Ikuo Nagata, Mitsuo Toyoshima, Yoshiaki Saito, Masayuki Itoh, Ichizo Nishino, Kousaku Ohn. Myocerebrohepatopathy spectrum disorder due to POLG mutations: A clinicopathological report. Brain & development. vol 37. issue 7. 2016-03-10. PMID:25466440. |
neuropathological examination revealed white matter-predominant spongy changes with alzheimer type ii glia and loss of myelin. |
2016-03-10 |
2023-08-13 |
Not clear |
| Willem Kamphuis, Lieneke Kooijman, Marie Orre, Oscar Stassen, Milos Pekny, Elly M Ho. GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease. Glia. vol 63. issue 6. 2016-01-08. PMID:25731615. |
gfap and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for alzheimer's disease. |
2016-01-08 |
2023-08-13 |
mouse |
| Janina Leyk, Olaf Goldbaum, Monika Noack, Christiane Richter-Landsber. Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance. Journal of molecular neuroscience : MN. vol 55. issue 4. 2015-11-27. PMID:25434725. |
proteinaceous inclusions in nerve cells and glia are a defining neuropathological hallmark in a variety of neurodegenerative diseases, including alzheimer's disease, parkinson's disease, progressive supranuclear palsy (psp), and corticobasal degeneration (cbd). |
2015-11-27 |
2023-08-13 |
Not clear |
| Marie Orre, Willem Kamphuis, Lana M Osborn, Anne H P Jansen, Lieneke Kooijman, Koen Bossers, Elly M Ho. Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction. Neurobiology of aging. vol 35. issue 12. 2015-11-09. PMID:25002035. |
isolation of glia from alzheimer's mice reveals inflammation and dysfunction. |
2015-11-09 |
2023-08-13 |
mouse |
| Joana R Guedes, Carlos M Custódia, Ricardo J Silva, Luís P de Almeida, Maria C Pedroso de Lima, Ana L Cardos. Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model. Human molecular genetics. vol 23. issue 23. 2015-10-29. PMID:24990149. |
the role of inflammatory mirnas in alzheimer's disease (ad) and their ability to modulate glia responses are now beginning to be explored. |
2015-10-29 |
2023-08-13 |
mouse |
| Florence C C Tan, Emmette R Hutchison, Erez Eitan, Mark P Mattso. Are there roles for brain cell senescence in aging and neurodegenerative disorders? Biogerontology. vol 15. issue 6. 2015-08-04. PMID:25305051. |
we suggest that there is a high level of similarity between some of the pathological changes that occur in the brain in alzheimer's and parkinson's diseases and those phenotypes observed in cellular senescence, leading us to propose that neurons and glia can exhibit hallmarks of senescence previously documented in peripheral tissues. |
2015-08-04 |
2023-08-13 |
Not clear |
| Xue Xue, Li-Rong Wang, Yutaka Sato, Ying Jiang, Martin Berg, Dun-Sheng Yang, Ralph A Nixon, Xing-Jie Lian. Single-walled carbon nanotubes alleviate autophagic/lysosomal defects in primary glia from a mouse model of Alzheimer's disease. Nano letters. vol 14. issue 9. 2015-07-14. PMID:25115676. |
single-walled carbon nanotubes alleviate autophagic/lysosomal defects in primary glia from a mouse model of alzheimer's disease. |
2015-07-14 |
2023-08-13 |
mouse |
| Lawrence Rajendran, Jitin Bali, Maureen M Barr, Felipe A Court, Eva-Maria Krämer-Albers, Frederic Picou, Graça Raposo, Kristan E van der Vos, Guillaume van Niel, Juan Wang, Xandra O Breakefiel. Emerging roles of extracellular vesicles in the nervous system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 46. 2015-02-09. PMID:25392515. |
these vesicles also have a sinister role in the propagation of toxic amyloid proteins in neurodegenerative conditions, including prion diseases and alzheimer's and parkinson's diseases, in inducing neuroinflammation by exchange of information between the neurons and glia, as well as in aiding tumor progression in the brain by subversion of normal cells. |
2015-02-09 |
2023-08-13 |
human |