| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Federica Rinaldi, Maeve A Caldwel. Modeling astrocytic contribution toward neurodegeneration with pluripotent stem cells: focus on Alzheimer's and Parkinson's diseases. Neuroreport. vol 24. issue 18. 2014-07-31. PMID:24201446. |
we have also focused on their involvement in neurodegenerative diseases including parkinson's and alzheimer's diseases, discussing the contribution of this type of glial cell toward mechanisms that can lead to neuronal death, which was previously attributed exclusively to neurons. |
2014-07-31 |
2023-08-12 |
Not clear |
| Sara M Hancock, David I Finkelstein, Paul A Adlar. Glia and zinc in ageing and Alzheimer's disease: a mechanism for cognitive decline? Frontiers in aging neuroscience. vol 6. 2014-07-10. PMID:25009495. |
glia and zinc in ageing and alzheimer's disease: a mechanism for cognitive decline? |
2014-07-10 |
2023-08-13 |
Not clear |
| H-M Yun, H S Kim, K-R Park, J M Shin, A R Kang, K il Lee, S Song, Y-B Kim, S B Han, H-M Chung, J T Hon. Placenta-derived mesenchymal stem cells improve memory dysfunction in an Aβ1-42-infused mouse model of Alzheimer's disease. Cell death & disease. vol 4. 2014-06-12. PMID:24336078. |
these data indicate that pd-msc mediates neuroprotection by regulating neuronal death, neurogenesis, glia cell activation in hippocampus, and altering cytokine expression, suggesting a close link between the therapeutic effects of mscs and the damaged cns in alzheimer's disease. |
2014-06-12 |
2023-08-12 |
mouse |
| Seung U Kim, Hong J Lee, Yun B Ki. Neural stem cell-based treatment for neurodegenerative diseases. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 33. issue 5. 2014-05-12. PMID:23384285. |
human neurodegenerative diseases such as parkinson's disease (pd), huntington's disease (hd), amyotrophic lateral sclerosis (als) and alzheimer's disease (ad) are caused by a loss of neurons and glia in the brain or spinal cord. |
2014-05-12 |
2023-08-12 |
human |
| Ramasamy Thangavel, Duraisamy Kempuraj, Deirdre Stolmeier, Poojya Anantharam, Mohammad Khan, Asgar Zahee. Glia maturation factor expression in entorhinal cortex of Alzheimer's disease brain. Neurochemical research. vol 38. issue 9. 2014-03-10. PMID:23715664. |
glia maturation factor expression in entorhinal cortex of alzheimer's disease brain. |
2014-03-10 |
2023-08-12 |
Not clear |
| Carlos Humberto Andrade-Moraes, Ana V Oliveira-Pinto, Emily Castro-Fonseca, Camila G da Silva, Daniel M Guimarães, Diego Szczupak, Danielle R Parente-Bruno, Ludmila R B Carvalho, Lívia Polichiso, Bruna V Gomes, Lays M Oliveira, Roberta D Rodriguez, Renata E P Leite, Renata E L Ferretti-Rebustini, Wilson Jacob-Filho, Carlos A Pasqualucci, Lea T Grinberg, Roberto Len. Cell number changes in Alzheimer's disease relate to dementia, not to plaques and tangles. Brain : a journal of neurology. vol 136. issue Pt 12. 2014-02-10. PMID:24136825. |
we found an increase of non-neuronal cell numbers in the cerebral cortex and subcortical white matter of demented patients with alzheimer's disease when compared with asymptomatic subjects with alzheimer's disease and control subjects, suggesting a reactive glial cell response in the former that may be related to the symptoms they present. |
2014-02-10 |
2023-08-12 |
human |
| Deirdre Stolmeier, Ramasamy Thangavel, Poojya Anantharam, Mohammad M Khan, Duraisamy Kempuraj, Asgar Zahee. Glia maturation factor expression in hippocampus of human Alzheimer's disease. Neurochemical research. vol 38. issue 8. 2014-02-06. PMID:23640177. |
glia maturation factor expression in hippocampus of human alzheimer's disease. |
2014-02-06 |
2023-08-12 |
human |
| Francisca Cornejo, Rommy von Bernhard. Role of scavenger receptors in glia-mediated neuroinflammatory response associated with Alzheimer's disease. Mediators of inflammation. vol 2013. 2013-12-03. PMID:23737655. |
here, we review the participation of the immune response mediated by glial cells in alzheimer's disease and the role played by scavenger receptors in the development of this pathology, focusing on the relevance of class a scavenger receptor (sr-a) for a β clearance and inflammatory activation of glial cell, and as a potential target for alzheimer's disease therapy. |
2013-12-03 |
2023-08-12 |
Not clear |
| Donna M Wilcock, W Sue T Griffi. Down's syndrome, neuroinflammation, and Alzheimer neuropathogenesis. Journal of neuroinflammation. vol 10. 2013-11-05. PMID:23866266. |
the discovery of neuroinflammatory changes, including dramatic proliferation of activated glia overexpressing a chromosome 2 gene product--the pluripotent immune cytokine interleukin-1 (il-1)--and a chromosome 21 gene product--s100b--in the brains of fetuses, neonates, and children with ds opened the possibility that early events in alzheimer pathogenesis were driven by cytokines. |
2013-11-05 |
2023-08-12 |
Not clear |
| Fangjun Wang, Alexandre P Blanchard, Fred Elisma, Matthew Granger, Hongbin Xu, Steffany A L Bennett, Daniel Figeys, Hanfa Zo. Phosphoproteome analysis of an early onset mouse model (TgCRND8) of Alzheimer's disease reveals temporal changes in neuronal and glia signaling pathways. Proteomics. vol 13. issue 8. 2013-09-20. PMID:23335269. |
phosphoproteome analysis of an early onset mouse model (tgcrnd8) of alzheimer's disease reveals temporal changes in neuronal and glia signaling pathways. |
2013-09-20 |
2023-08-12 |
mouse |
| Seung Hwan Park, Soojin Lee, Yoon Ki Hong, Soojin Hwang, Jang Ho Lee, Se Min Bang, Young-Kyoon Kim, Byung-Soo Koo, Im-Soon Lee, Kyoung Sang Ch. Suppressive effects of SuHeXiang Wan on amyloid-β42-induced extracellular signal-regulated kinase hyperactivation and glial cell proliferation in a transgenic Drosophila model of Alzheimer's disease. Biological & pharmaceutical bulletin. vol 36. issue 3. 2013-08-27. PMID:23238278. |
suppressive effects of suhexiang wan on amyloid-β42-induced extracellular signal-regulated kinase hyperactivation and glial cell proliferation in a transgenic drosophila model of alzheimer's disease. |
2013-08-27 |
2023-08-12 |
drosophila_melanogaster |
| Santiago Solé-Domènech, Peter Sjövall, Vladana Vukojević, Ruani Fernando, Alina Codita, Sachin Salve, Nenad Bogdanović, Abdul H Mohammed, Per Hammarström, K Peter R Nilsson, Frank M LaFerla, Stefan Jacob, Per-Olof Berggren, Lydia Giménez-Llort, Martin Schalling, Lars Terenius, Björn Johansso. Localization of cholesterol, amyloid and glia in Alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging. Acta neuropathologica. vol 125. issue 1. 2013-08-06. PMID:22996963. |
localization of cholesterol, amyloid and glia in alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (tof-sims) and immunofluorescence imaging. |
2013-08-06 |
2023-08-12 |
mouse |
| Marie Orre, Willem Kamphuis, Stephanie Dooves, Lieneke Kooijman, Elena T Chan, Christopher J Kirk, Vanessa Dimayuga Smith, Sanne Koot, Carlyn Mamber, Anne H Jansen, Huib Ovaa, Elly M Ho. Reactive glia show increased immunoproteasome activity in Alzheimer's disease. Brain : a journal of neurology. vol 136. issue Pt 5. 2013-06-24. PMID:23604491. |
reactive glia show increased immunoproteasome activity in alzheimer's disease. |
2013-06-24 |
2023-08-12 |
mouse |
| Smita Zaheer, Ramasamy Thangavel, Yanghong Wu, Mohammad Moshahid Khan, Duraisamy Kempuraj, Asgar Zahee. Enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic Alzheimer's disease mice. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:23086473. |
enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic alzheimer's disease mice. |
2013-05-29 |
2023-08-12 |
mouse |
| R Thangavel, D Stolmeier, X Yang, P Anantharam, A Zahee. Expression of glia maturation factor in neuropathological lesions of Alzheimer's disease. Neuropathology and applied neurobiology. vol 38. issue 6. 2013-02-22. PMID:22035352. |
expression of glia maturation factor in neuropathological lesions of alzheimer's disease. |
2013-02-22 |
2023-08-12 |
Not clear |
| Chang Su, Rebecca L Cunningham, Nataliya Rybalchenko, Meharvan Sing. Progesterone increases the release of brain-derived neurotrophic factor from glia via progesterone receptor membrane component 1 (Pgrmc1)-dependent ERK5 signaling. Endocrinology. vol 153. issue 9. 2012-10-29. PMID:22778217. |
collectively, our data describe that p4 elicits an increase in bdnf release from glia via a pgrmc1-induced erk5 signaling mechanism and identify pgrmc1 as a potential therapeutic target for future hormone-based drug development for the treatment of such degenerative diseases as alzheimer's disease as well as other diseases wherein neurotrophin dysregulation is noted. |
2012-10-29 |
2023-08-12 |
Not clear |
| Cristina Benito, Rosa María Tolón, Ana Isabel Castillo, Lourdes Ruiz-Valdepeñas, José Antonio Martínez-Orgado, Francisco Javier Fernández-Sánchez, Carmen Vázquez, Benjamin F Cravatt, Julián Romer. β-Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB₁ or CB₂ receptors. British journal of pharmacology. vol 166. issue 4. 2012-10-09. PMID:22321194. |
the endocannabinoid system may regulate glial cell functions and their responses to pathological stimuli, specifically, alzheimer's disease. |
2012-10-09 |
2023-08-12 |
Not clear |
| Yazi D Ke, Alexandra K Suchowerska, Julia van der Hoven, Dineeka M De Silva, Christopher W Wu, Janet van Eersel, Arne Ittner, Lars M Ittne. Lessons from tau-deficient mice. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22720190. |
both alzheimer's disease (ad) and frontotemporal dementia (ftd) are characterized by the deposition of hyperphosphorylated forms of the microtubule-associated protein tau in neurons and/or glia. |
2012-08-23 |
2023-08-12 |
mouse |
| Rommy von Bernhardi, Jaime Eugení. Alzheimer's disease: redox dysregulation as a common denominator for diverse pathogenic mechanisms. Antioxidants & redox signaling. vol 16. issue 9. 2012-07-09. PMID:22122400. |
alzheimer's disease (ad) is the most common cause of dementia and a progressive neurodegeneration that appears to result from multiple pathogenic mechanisms (including protein misfolding/aggregation, involved in both amyloid β-dependent senile plaques and tau-dependent neurofibrillary tangles), metabolic and mitochondrial dysfunction, excitoxicity, calcium handling impairment, glial cell dysfunction, neuroinflammation, and oxidative stress. |
2012-07-09 |
2023-08-12 |
Not clear |
| S Zaheer, R Thangavel, S K Sahu, A Zahee. Augmented expression of glia maturation factor in Alzheimer's disease. Neuroscience. vol 194. 2012-06-25. PMID:21835226. |
augmented expression of glia maturation factor in alzheimer's disease. |
2012-06-25 |
2023-08-12 |
Not clear |