| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pengyun Ni, Kaiting Pan, Bingbing Zha. Influence of N6-methyladenosine (m6A) modification on cell phenotype in Alzheimer's disease. PloS one. vol 18. issue 8. 2023-08-07. PMID:37549144. |
influence of n6-methyladenosine (m6a) modification on cell phenotype in alzheimer's disease. |
2023-08-07 |
2023-08-14 |
Not clear |
| Thomas Gabriel Schreiner, Bogdan Ionel Tamba, Cosmin Teodor Mihai, Adam Lőrinczi, Mihaela Baibarac, Romeo Cristian Ciobanu, Bogdan Ovidiu Popesc. Nanoporous Membranes for the Filtration of Proteins from Biological Fluids: Biocompatibility Tests on Cell Cultures and Suggested Applications for the Treatment of Alzheimer's Disease. Journal of clinical medicine. vol 11. issue 19. 2022-10-14. PMID:36233713. |
nanoporous membranes for the filtration of proteins from biological fluids: biocompatibility tests on cell cultures and suggested applications for the treatment of alzheimer's disease. |
2022-10-14 |
2023-08-14 |
Not clear |
| Qian Guo, Qinfeng Cai, Fang Huang, Zhen Wei, Jian-Zhi Wang, Bin Zhang, Rong Liu, Yang Yang, Xiaochuan Wang, Hong-Lian L. The Therapeutic Effects of Seven Lycophyte Compounds on Cell Models of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-10-03. PMID:36189599. |
the therapeutic effects of seven lycophyte compounds on cell models of alzheimer's disease. |
2022-10-03 |
2023-08-14 |
Not clear |
| Bin Wang, Cong Gu. Concentration-Dependent Effects of Cholesterol on the Dimerization of Amyloid-β Peptides in Lipid Bilayers. ACS chemical neuroscience. 2022-09-09. PMID:36082607. |
membrane disruption mediated by the accumulation of amyloid-β (aβ) on cell membranes is central to the pathogenesis of alzheimer's disease (ad). |
2022-09-09 |
2023-08-14 |
Not clear |
| Jia Wang, Si-Fei Ma, Qi Yun, Wen-Jun Liu, Hong-Ru Zhai, Hou-Zhen Shi, Lan-Gui Xie, Jin-Jun Qian, Chun-Jie Zhao, Wei-Ning Zhan. FOXG1 as a Potential Therapeutic Target for Alzheimer's Disease with a Particular Focus on Cell Cycle Regulation. Journal of Alzheimer's disease : JAD. 2022-02-18. PMID:35180113. |
foxg1 as a potential therapeutic target for alzheimer's disease with a particular focus on cell cycle regulation. |
2022-02-18 |
2023-08-13 |
Not clear |
| Jelena Osmanovic Barilar, Ana Knezovic, Jan Homolak, Ana Babic Perhoc, Melita Salkovic-Petrisi. Divergent Effect of Central Incretin Receptors Inhibition in a Rat Model of Sporadic Alzheimer's Disease. International journal of molecular sciences. vol 23. issue 1. 2022-01-11. PMID:35008973. |
this study aimed to explore the roles of central glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip) on cell metabolism and energy in the brain, as well as on the levels of these incretins, insulin, and glucose via inhibition of the central incretin receptors following intracerebroventricular administration of the respective antagonists in healthy rats and a streptozotocin-induced rat model of sporadic alzheimer's disease (sad). |
2022-01-11 |
2023-08-13 |
rat |
| Jingcong Zhuang, Zhongjie Chen, Pingping Cai, Rong Wang, Qingwei Yang, Longling Li, Huili Yang, Renjing Zh. Targeting MicroRNA-125b Promotes Neurite Outgrowth but Represses Cell Apoptosis and Inflammation via Blocking PTGS2 and CDK5 in a FOXQ1-Dependent Way in Alzheimer Disease. Frontiers in cellular neuroscience. vol 14. 2021-01-11. PMID:33408612. |
this study aimed to explore the molecular regulatory network among microrna-125b (mir-125b), forkhead box q1 (foxq1), prostaglandin-endoperoxide synthase 2 (ptgs2), and cyclin-dependent kinase 5 (cdk5), as well as their effects on cell apoptosis, neurite outgrowth, and inflammation in alzheimer disease (ad). |
2021-01-11 |
2023-08-13 |
rat |
| Weiwei Yang, Sheng Zhang, Biao Li, Yao Zhan. [MALAT1 inhibits proliferation and promotes apoptosis of SH-SY5Y cells induced by Aβ Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 34. issue 5. 2019-07-08. PMID:30043735. |
[malat1 inhibits proliferation and promotes apoptosis of sh-sy5y cells induced by aβ objective to investigate the effects of long non-coding rna (lncrna) metastasis-associated lung adenocarcinoma transcript 1 (malat1) on cell cycle, proliferation and apoptosis in sh-sy5y model cells of alzheimer's disease (ad). |
2019-07-08 |
2023-08-13 |
human |
| Francesco Angelucci, Francesca Gelfo, Marco Fiore, Nicoletta Croce, Aleksander A Mathé, Sergio Bernardini, Carlo Caltagiron. The effect of neuropeptide Y on cell survival and neurotrophin expression in in-vitro models of Alzheimer's disease. Canadian journal of physiology and pharmacology. vol 92. issue 8. 2015-05-11. PMID:25026432. |
the effect of neuropeptide y on cell survival and neurotrophin expression in in-vitro models of alzheimer's disease. |
2015-05-11 |
2023-08-13 |
Not clear |
| Daniela Puzzo, Carla Loreto, Salvatore Giunta, Giuseppe Musumeci, Giuseppina Frasca, Maria Vittoria Podda, Ottavio Arancio, Agostino Palmer. Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice. Neurobiology of aging. vol 35. issue 3. 2014-09-29. PMID:24112792. |
because it has been previously demonstrated that phosphodiesterase-5 inhibitors (pde5-is) protect against hippocampal synaptic dysfunction and memory deficits in mouse models of alzheimer's disease and physiological aging, we investigated the effect of a treatment with the pde5-i, sildenafil, on cell death, pro- and antiapoptotic molecules, and aβ production. |
2014-09-29 |
2023-08-12 |
mouse |
| Carolina Adura, Simon Guerrero, Edison Salas, Luis Medel, Ana Riveros, Juan Mena, Jordi Arbiol, Fernando Albericio, Ernest Giralt, Marcelo J Koga. Stable conjugates of peptides with gold nanorods for biomedical applications with reduced effects on cell viability. ACS applied materials & interfaces. vol 5. issue 10. 2013-10-17. PMID:23597259. |
in this study, we produced a conjugate of gold nanorods with the peptide clpffd that recognizes toxic β-amyloid aggregates present in alzheimer's disease, demonstrates colloidal stability, maintains plasmonic properties, and shows no effects on cell viability in the sh-sy5y cell line. |
2013-10-17 |
2023-08-12 |
Not clear |
| Shuke Cui, Yan Sun, Chengzang Li. Effect of bushenyisui formula on brain tissue apoptosis and Bcl-2 in beta-amyloid protein-induced Alzheimer's disease rat models. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 32. issue 4. 2013-04-04. PMID:23427404. |
to investigate the effect of bushenyisui formula on cell apoptosis and positive b cell lymphoma (bcl-2) in the brain of rat models of alzheimer's disease (ad) induced by beta-amyloid protein (abeta) and the mechanism underlying the effect. |
2013-04-04 |
2023-08-12 |
rat |
| Willem Kamphuis, Marie Orre, Lieneke Kooijman, Maurice Dahmen, Elly M Ho. Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model. Glia. vol 60. issue 4. 2012-06-12. PMID:22262260. |
plaque deposition in alzheimer's disease (ad) is known to decrease proliferation in neurogenic niches in ad mouse models, but the effects on cell proliferation and differentiation in other brain areas have not been studied in detail. |
2012-06-12 |
2023-08-12 |
mouse |
| Xiaoguang Yang, Wenwen Sheng, Grace Y Sun, James C-M Le. Effects of fatty acid unsaturation numbers on membrane fluidity and α-secretase-dependent amyloid precursor protein processing. Neurochemistry international. vol 58. issue 3. 2011-12-27. PMID:21184792. |
to address the roles of fatty acid unsaturation numbers in cellular pathways of alzheimer's disease (ad), we systematically investigated the effects of fatty acids on cell membrane fluidity and α-secretase-cleaved soluble amyloid precursor protein (sapp(α)) secretion in relation to unsaturation numbers using stearic acid (sa, 18:0), oleic acid (oa, 18:1), linoleic acid (la, 18:2), α-linolenic acid (ala, 18:3), arachidonic acid (aa, 20:4), eicosapentaenoic acid (epa, 20:5), and docosahexaenoic acid (dha, 22:6). |
2011-12-27 |
2023-08-12 |
human |
| Steven S-S Wang, Ming-Shen Lin, Shen-Liang Chen, Yung Chang, Rouch-Chyu Ruaan, Wen-Yih Che. Using isothermal titration calorimetry to real-time monitor the heat of metabolism: a case study using PC12 cells and Aβ(1-40). Colloids and surfaces. B, Biointerfaces. vol 83. issue 2. 2011-04-25. PMID:21190816. |
the deposition and aggregation of β-amyloid (aβ) on cell membranes was considered as one of the primary factors in having alzheimer's disease (ad). |
2011-04-25 |
2023-08-12 |
Not clear |
| Suman Nag, Jiji Chen, J Irudayaraj, S Mait. Measurement of the attachment and assembly of small amyloid-β oligomers on live cell membranes at physiological concentrations using single-molecule tools. Biophysical journal. vol 99. issue 6. 2011-01-04. PMID:20858443. |
it is thought that the pathological cascade in alzheimer's disease is initiated by the formation of amyloid-β (aβ) peptide complexes on cell membranes. |
2011-01-04 |
2023-08-12 |
Not clear |
| Zhi-qiang Xu, Jing Li, Juan Deng, Xiao-jiang Jiang, Hua-dong Zho. [Effects of proBDNF on cell proliferation and differentiation in hippocampal dentate gyrus in Alzheimer' disease rat model]. Zhonghua yi xue za zhi. vol 90. issue 19. 2010-09-09. PMID:20646587. |
[effects of probdnf on cell proliferation and differentiation in hippocampal dentate gyrus in alzheimer' disease rat model]. |
2010-09-09 |
2023-08-12 |
rat |
| Zhi-qiang Xu, Jing Li, Juan Deng, Xiao-jiang Jiang, Hua-dong Zho. [Effects of proBDNF on cell proliferation and differentiation in hippocampal dentate gyrus in Alzheimer' disease rat model]. Zhonghua yi xue za zhi. vol 90. issue 19. 2010-09-09. PMID:20646587. |
to explore the effects of probdnf on cell proliferation and differentiation in hippocampal dentate gyrus in alzheimer' disease (ad) rat model. |
2010-09-09 |
2023-08-12 |
rat |
| Alex Perálvarez-Marín, Laura Mateos, Ce Zhang, Shalini Singh, Angel Cedazo-Mínguez, Neus Visa, Ludmilla Morozova-Roche, Astrid Gräslund, Andreas Bart. Influence of residue 22 on the folding, aggregation profile, and toxicity of the Alzheimer's amyloid beta peptide. Biophysical journal. vol 97. issue 1. 2009-10-13. PMID:19580765. |
several biophysical techniques have been used to determine differences in the aggregation profile (i.e., the secondary structure, aggregation propensity, dynamics, and morphology of amyloid structures) and the effects on cell viability of three variants of the amyloid beta peptide involved in alzheimer's disease. |
2009-10-13 |
2023-08-12 |
human |
| Yuichi Hashimoto, Megumi Kurita, Sadakazu Aiso, Ikuo Nishimoto, Masaaki Matsuok. Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130. Molecular biology of the cell. vol 20. issue 12. 2009-09-21. PMID:19386761. |
humanin (hn) inhibits neuronal death induced by various alzheimer's disease (ad)-related insults via an unknown receptor on cell membranes. |
2009-09-21 |
2023-08-12 |
Not clear |