| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhi Huang, Gennifer E Merrihew, Eric B Larson, Jea Park, Deanna Plubell, Edward J Fox, Kathleen S Montine, Caitlin S Latimer, C Dirk Keene, James Y Zou, Michael J MacCoss, Thomas J Montin. Brain proteomic analysis implicates actin filament processes and injury response in resilience to Alzheimer's disease. Nature communications. vol 14. issue 1. 2023-05-14. PMID:37173305. |
here we assessed 43 research participants meeting stringent criteria, 11 healthy controls, 12 resilience to alzheimer's disease and 20 alzheimer's disease with dementia and analyzed matched isocortical regions, hippocampus, and caudate nucleus by mass spectrometry-based proteomics. |
2023-05-14 |
2023-08-14 |
human |
| b' Zden\\xc4\\x9bk Wurst, Barbora Bir\\xc4\\x8d\\xc3\\xa1k Kuchtov\\xc3\\xa1, Jan K\\xc5\\x99emen, Anastasiya Lahutsina, Ibrahim Ibrahim, Jaroslav Tint\\xc4\\x9bra, Ale\\xc5\\xa1 Barto\\xc5\\xa1, Marek Brabec, Tanya Rai, Petr Zach, Vladim\\xc3\\xadr Musil, Nicoletta Olympiou, Jana Mrz\\xc3\\xadlkov\\xc3\\xa. Basal Ganglia Compensatory White Matter Changes on DTI in Alzheimer\'s Disease. Cells. vol 12. issue 9. 2023-05-14. PMID:37174620.' |
a significant decrease in the number of tracts and general fractional anisotropy was found in patients with alzheimer's disease compared to controls in the right caudate nucleus, while an increase was found in the left and the right putamen. |
2023-05-14 |
2023-08-14 |
Not clear |
| b' Zden\\xc4\\x9bk Wurst, Barbora Bir\\xc4\\x8d\\xc3\\xa1k Kuchtov\\xc3\\xa1, Jan K\\xc5\\x99emen, Anastasiya Lahutsina, Ibrahim Ibrahim, Jaroslav Tint\\xc4\\x9bra, Ale\\xc5\\xa1 Barto\\xc5\\xa1, Marek Brabec, Tanya Rai, Petr Zach, Vladim\\xc3\\xadr Musil, Nicoletta Olympiou, Jana Mrz\\xc3\\xadlkov\\xc3\\xa. Basal Ganglia Compensatory White Matter Changes on DTI in Alzheimer\'s Disease. Cells. vol 12. issue 9. 2023-05-14. PMID:37174620.' |
the right caudate showed a decrease in both the diffusion tensor imaging parameters and the volume in alzheimer's disease patients. |
2023-05-14 |
2023-08-14 |
Not clear |
| Rebecca L Winfree, Mabel Seto, Logan Dumitrescu, Vilas Menon, Philip De Jager, Yanling Wang, Julie Schneider, David A Bennett, Angela L Jefferson, Timothy J Hohma. TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia. Acta neuropathologica. 2023-03-25. PMID:36966244. |
trem2 gene expression of the dorsolateral prefrontal cortex, posterior cingulate cortex, and caudate nucleus was assessed with respect to core pathology of alzheimer's disease (amyloid-β, and tau), cerebrovascular pathology (cerebral infarcts, arteriolosclerosis, atherosclerosis, and cerebral amyloid angiopathy), microglial activation (proportion of activated microglia), and cognitive performance. |
2023-03-25 |
2023-08-14 |
Not clear |
| Hunter White, Ryan Webb, Ian McKnight, Kaitlyn Legg, Chan Lee, Peter H U Lee, Olivia Smith Spicer, Joon W Shi. TRPV4 mRNA is elevated in the caudate nucleus with NPH but not in Alzheimer's disease. Frontiers in genetics. vol 13. 2022-11-21. PMID:36406122. |
trpv4 mrna is elevated in the caudate nucleus with nph but not in alzheimer's disease. |
2022-11-21 |
2023-08-14 |
mouse |
| Petr Dusek, Tim Hofer, Jan Alexander, Per M Roos, Jan O Aaset. Cerebral Iron Deposition in Neurodegeneration. Biomolecules. vol 12. issue 5. 2022-05-28. PMID:35625641. |
the second group of disorders including multiple sclerosis, alzheimer's disease, and amyotrophic lateral sclerosis shows iron accumulation in the globus pallidus, caudate, and putamen, and in specific cortical regions. |
2022-05-28 |
2023-08-13 |
Not clear |
| Xiaotong Wei, Xiaotong Du, Yingying Xie, Xinjun Suo, Xiaoxi He, Hao Ding, Yu Zhang, Yi Ji, Chao Chai, Meng Liang, Chunshui Yu, Yong Liu, Wen Qi. Mapping cerebral atrophic trajectory from amnestic mild cognitive impairment to Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). 2022-04-03. PMID:35368064. |
by mapping the region-specific nonlinear atrophic trajectory of whole cerebrum from amnestic mild cognitive impairment (amci) to ad based on longitudinal structural magnetic resonance imaging data from alzheimer's disease neuroimaging initiative (adni) database, we unraveled a quadratic accelerated atrophic trajectory of 68 cerebral regions from amci to ad, especially in the superior temporal pole, caudate, and hippocampus. |
2022-04-03 |
2023-08-13 |
Not clear |
| Eric E Abrahamson, Julia K Kofler, Carl R Becker, Julie C Price, Kathy L Newell, Bernardino Ghetti, Jill R Murrell, Catriona A McLean, Oscar L Lopez, Chester A Mathis, William E Klunk, Victor L Villemagne, Milos D Ikonomovi. 11C-PiB PET can underestimate brain amyloid-β burden when cotton wool plaques are numerous. Brain : a journal of neurology. 2021-12-17. PMID:34918018. |
histological sections of frontal and temporal cortex, caudate nucleus, and cerebellum were obtained from 14 cases with sporadic alzheimer's disease, 12 cases with familial alzheimer's disease due to psen1 mutations, two relatives of a psen1 mutation carrier but without genotype information, and three non-alzheimer's disease cases. |
2021-12-17 |
2023-08-13 |
human |
| Eric E Abrahamson, Julia K Kofler, Carl R Becker, Julie C Price, Kathy L Newell, Bernardino Ghetti, Jill R Murrell, Catriona A McLean, Oscar L Lopez, Chester A Mathis, William E Klunk, Victor L Villemagne, Milos D Ikonomovi. 11C-PiB PET can underestimate brain amyloid-β burden when cotton wool plaques are numerous. Brain : a journal of neurology. 2021-12-17. PMID:34918018. |
cotton wool plaques were present in the neocortex of all familial alzheimer's disease cases and one sporadic alzheimer's disease case, in the caudate nucleus from four familial alzheimer's disease cases, but not in the cerebellum. |
2021-12-17 |
2023-08-13 |
human |
| Eric E Abrahamson, Julia K Kofler, Carl R Becker, Julie C Price, Kathy L Newell, Bernardino Ghetti, Jill R Murrell, Catriona A McLean, Oscar L Lopez, Chester A Mathis, William E Klunk, Victor L Villemagne, Milos D Ikonomovi. 11C-PiB PET can underestimate brain amyloid-β burden when cotton wool plaques are numerous. Brain : a journal of neurology. 2021-12-17. PMID:34918018. |
relative to amyloid-β plaque load, cyano-pittsburgh compound-b plaque load was similar in sporadic alzheimer's disease while in familial alzheimer's disease it was lower in the neocortex and the caudate nucleus. |
2021-12-17 |
2023-08-13 |
human |
| Huifangjie Li, William C Knight, Jinbin X. Striatal oxidative damages and neuroinflammation correlate with progression and survival of Lewy body and Alzheimer diseases. Neural regeneration research. vol 17. issue 4. 2021-11-10. PMID:34472487. |
in this observational study, we have examined diverse biochemical parameters in the caudate and putamen of patients with lewy body diseases (lbds) and alzheimer disease (ad), shedding some light on the involvement of oxidative damage and neuroinflammation in advanced neurodegeneration. |
2021-11-10 |
2023-08-13 |
Not clear |
| Devin J Sodums, Véronique D Bohbo. Negative correlation between grey matter in the hippocampus and caudate nucleus in healthy aging. Hippocampus. vol 30. issue 8. 2021-11-05. PMID:32384195. |
furthermore, we previously showed a negative correlation between grey matter in the hippocampus and caudate nucleus/striatum in mice, young adults, and in individuals diagnosed with alzheimer's disease. |
2021-11-05 |
2023-08-13 |
mouse |
| Tomoko Miki, Osamu Yokota, Takashi Haraguchi, Hideki Ishizu, Masato Hasegawa, Takeshi Ishihara, Shu-Ichi Ueno, Shintaro Takenoshita, Seishi Terada, Norihito Yamad. Factors associated with development and distribution of granular/fuzzy astrocytes in neurodegenerative diseases. Brain pathology (Zurich, Switzerland). vol 30. issue 4. 2021-06-22. PMID:32293067. |
we immunohistochemically examined the frontal cortex, caudate nucleus, putamen and amygdala in 105 cases composed of argyrophilic grain disease cases (agd, n = 26), and progressive supranuclear palsy (psp, n = 10), alzheimer's disease (ad, n = 20) and primary age-related tauopathy cases (part, n = 18) lacking agd, as well as 31 cases bearing other various neurodegenerative diseases to clarify (i) the distribution patterns of gfas in agd, and psp, ad and part lacking agd, (ii) the impacts of major pathological factors and age on gfa formation and (iii) immunohistochemical features useful to understand the formation process of gfas. |
2021-06-22 |
2023-08-13 |
Not clear |
| Mahsa Dadar, Olivier Potvin, Richard Camicioli, Simon Duchesn. Beware of white matter hyperintensities causing systematic errors in FreeSurfer gray matter segmentations! Human brain mapping. vol 42. issue 9. 2021-05-23. PMID:33783933. |
when not corrected for wmhs, caudate volumes increased with age (p < .0001) and were not different between cognitively healthy individuals and age-matched probable alzheimer's disease patients. |
2021-05-23 |
2023-08-13 |
human |
| Mahsa Dadar, Olivier Potvin, Richard Camicioli, Simon Duchesn. Beware of white matter hyperintensities causing systematic errors in FreeSurfer gray matter segmentations! Human brain mapping. vol 42. issue 9. 2021-05-23. PMID:33783933. |
after correcting for wmhs, caudate volumes decreased with age (p < .0001), and alzheimer's disease patients had lower caudate volumes than cognitively healthy individuals (p < .01). |
2021-05-23 |
2023-08-13 |
human |
| Huifangjie Li, William C Knight, Pengfei Yang, Yingqiu Guo, Joel S Perlmutter, John C Morris, Randall J Bateman, Tammie L S Benzinger, Jinbin X. Microglia Implicated in Tauopathy in the Striatum of Neurodegenerative Disease Patients from Genotype to Phenotype. International journal of molecular sciences. vol 21. issue 17. 2021-04-09. PMID:32842621. |
we chose the caudate and putamen of lewy body diseases (lbds) (parkinson's disease, parkinson's disease dementia, and dementia with lewy body), alzheimer's disease (ad), and control brains and genotyped for |
2021-04-09 |
2023-08-13 |
Not clear |
| Parsa Ravanfar, Samantha M Loi, Warda T Syeda, Tamsyn E Van Rheenen, Ashley I Bush, Patricia Desmond, Vanessa L Cropley, Darius J R Lane, Carlos M Opazo, Bradford A Moffat, Dennis Velakoulis, Christos Panteli. Systematic Review: Quantitative Susceptibility Mapping (QSM) of Brain Iron Profile in Neurodegenerative Diseases. Frontiers in neuroscience. vol 15. 2021-03-10. PMID:33679303. |
as a general pattern, qsm revealed increased magnetic susceptibility (suggestive of increased iron content) in the brain regions associated with the pathology of each disorder, such as the amygdala and caudate nucleus in alzheimer's disease, the substantia nigra in parkinson's disease, motor cortex in amyotrophic lateral sclerosis, basal ganglia in huntington's disease, and cerebellar dentate nucleus in friedreich's ataxia. |
2021-03-10 |
2023-08-13 |
Not clear |
| Niki Udo, Naoki Hashimoto, Takuya Toyonaga, Tomoyuki Isoyama, Yuka Oyanagi, Hisashi Narita, Tohru Shiga, Shin Nakagawa, Ichiro Kusum. Apathy in Alzheimer's Disease Correlates with the Dopamine Transporter Level in the Caudate Nuclei. Dementia and geriatric cognitive disorders extra. vol 10. issue 2. 2020-10-22. PMID:33082772. |
apathy in alzheimer's disease correlates with the dopamine transporter level in the caudate nuclei. |
2020-10-22 |
2023-08-13 |
Not clear |
| Oishi, Mochizuki, Takas. Regional differences in cerebrovascular reactivity to acetazolamide in Alzheimer's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 6. issue 5. 2019-11-20. PMID:10844775. |
the blood flows in the frontal lobe, parietal lobe and temporal lobe were reduced but the blood flows in the caudate nucleus, putamen and thalamus were normal in the alzheimer's disease group. |
2019-11-20 |
2023-08-12 |
human |
| K Persson, V D Bohbot, N Bogdanovic, G Selbaek, A Braekhus, K Engeda. Finding of increased caudate nucleus in patients with Alzheimer's disease. Acta neurologica Scandinavica. vol 137. issue 2. 2018-06-28. PMID:28741672. |
finding of increased caudate nucleus in patients with alzheimer's disease. |
2018-06-28 |
2023-08-13 |
Not clear |