| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Asokan Prema, Arokiasamy Justin Thenmozhi, Thamilarasan Manivasagam, Musthafa Mohamed Essa, Gilles J Guillemi. Fenugreek Seed Powder Attenuated Aluminum Chloride-Induced Tau Pathology, Oxidative Stress, and Inflammation in a Rat Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 60. issue s1. 2018-04-06. PMID:28269780. |
alzheimer's disease (ad) is a common neurodegenerative disorder that mainly affects the aged population and is characterized by the progressive loss of the hippocampal and cortical neurons, which results in memory and cognitive impairments. |
2018-04-06 |
2023-08-13 |
rat |
| Jorge Valero, Liliana Bernardino, Filipa Lourenço Cardoso, Ana Paula Silva, Carlos Fontes-Ribeiro, António Francisco Ambrósio, João Oliveira Malv. Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 60. issue s1. 2018-04-06. PMID:28671124. |
impact of neuroinflammation on hippocampal neurogenesis: relevance to aging and alzheimer's disease. |
2018-04-06 |
2023-08-13 |
Not clear |
| Jorge Valero, Liliana Bernardino, Filipa Lourenço Cardoso, Ana Paula Silva, Carlos Fontes-Ribeiro, António Francisco Ambrósio, João Oliveira Malv. Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 60. issue s1. 2018-04-06. PMID:28671124. |
on the other side, neuroinflammation, by releasing a plethora of proinflammatory cytokines and other inflammatory molecules, is increasingly shown to be one of the key determinant pathophysiological factors that negatively impact on neurogenesis and on the cognitive reserve, playing a detrimental role in hippocampal neurogenic niche dynamics and in the progression of neurodegenerative diseases, such as alzheimer's disease. |
2018-04-06 |
2023-08-13 |
Not clear |
| Jason C You, Gabriel S Stephens, Chia-Hsuan Fu, Xiaohong Zhang, Yin Liu, Jeannie Chi. Genome-wide profiling reveals functional diversification of ∆FosB gene targets in the hippocampus of an Alzheimer's disease mouse model. PloS one. vol 13. issue 2. 2018-04-02. PMID:29408867. |
genome-wide profiling reveals functional diversification of ∆fosb gene targets in the hippocampus of an alzheimer's disease mouse model. |
2018-04-02 |
2023-08-13 |
mouse |
| Jason C You, Gabriel S Stephens, Chia-Hsuan Fu, Xiaohong Zhang, Yin Liu, Jeannie Chi. Genome-wide profiling reveals functional diversification of ∆FosB gene targets in the hippocampus of an Alzheimer's disease mouse model. PloS one. vol 13. issue 2. 2018-04-02. PMID:29408867. |
the activity-induced transcription factor ∆fosb has been implicated in alzheimer's disease (ad) as a critical regulator of hippocampal function and cognition downstream of seizures and network hyperexcitability. |
2018-04-02 |
2023-08-13 |
mouse |
| Francesco Brun, Francesco Sensi, Rossella Quartulli, Luca Rei, Alban Grucka, Valentina Mancarella, Andrea Chincarini, Maja Ukmar, Agostino Accardo, Renata Long. Medial temporal lobe high resolution magnetic resonance images for the early diagnosis of Alzheimer's disease. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2015. 2018-03-30. PMID:26737239. |
refined image processing techniques were already proposed to automatically extract the hippocampal boxes from images acquired with the standard full brain acquisition protocol suggested by the alzheimer's disease neuroimaging initiative (adni). |
2018-03-30 |
2023-08-13 |
Not clear |
| Diya Wang, Jianbin Zhang, Wenkai Jiang, Zipeng Cao, Fang Zhao, Tongjian Cai, Michael Aschner, Wenjing Lu. The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability. Autophagy. vol 13. issue 5. 2018-03-29. PMID:28318352. |
the accumulation of proinflammatory cytokines, such as il1b (interleukin 1 β) and il18 (interleukin 18), as well as the dysfunctional autophagy pathway may damage hippocampal neuronal cells, thus leading to hippocampal-dependent impairment in learning and memory, which is associated with the pathogenesis of alzheimer disease (ad). |
2018-03-29 |
2023-08-13 |
mouse |
| Weiwei Lin, Jianmei Zhang, Yanmeng Liu, Ruijun Wu, Haisong Yang, Xiaobo Hu, Xiaomei Lin. Studies on diagnostic biomarkers and therapeutic mechanism of Alzheimer's disease through metabolomics and hippocampal proteomics. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 105. 2018-03-23. PMID:28495476. |
studies on diagnostic biomarkers and therapeutic mechanism of alzheimer's disease through metabolomics and hippocampal proteomics. |
2018-03-23 |
2023-08-13 |
rat |
| I Moonga, F Niccolini, H Wilson, G Pagano, M Politi. Hypertension is associated with worse cognitive function and hippocampal hypometabolism in Alzheimer's disease. European journal of neurology. vol 24. issue 9. 2018-03-23. PMID:28752644. |
hypertension is associated with worse cognitive function and hippocampal hypometabolism in alzheimer's disease. |
2018-03-23 |
2023-08-13 |
Not clear |
| Chun-Han Liu, Lian Li. A Novel Method to Identify Differential Pathways in Hippocampus Alzheimer's Disease. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-22. PMID:28479591. |
a novel method to identify differential pathways in hippocampus alzheimer's disease. |
2018-03-22 |
2023-08-13 |
Not clear |
| Yufang Guo, Yan Zhao, Ying Nan, Xiang Wang, Yulong Chen, Shuang Wan. (-)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of Alzheimer's disease. Neuroreport. vol 28. issue 10. 2018-03-22. PMID:28520620. |
(-)-epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of alzheimer's disease. |
2018-03-22 |
2023-08-13 |
mouse |
| Manon Thierry, Serge Marty, Susana Boluda, Charles Duyckaert. Alzheimer's senile plaque as shown by microcryodissection, a new technique for dissociating tissue structures. Journal of neural transmission (Vienna, Austria : 1996). vol 124. issue 6. 2018-03-20. PMID:28386671. |
samples of neocortex, hippocampus and striatum were taken from formalin-fixed brains (one control case; three cases with severe alzheimer disease). |
2018-03-20 |
2023-08-13 |
Not clear |
| Damian M Cummings, Tiffanie A Benway, Hinze Ho, Angelo Tedoldi, Monica M Fernandes Freitas, Lion Shahab, Christina E Murray, Angela Richard-Loendt, Sebastian Brandner, Tammaryn Lashley, Dervis A Salih, Frances A Edward. Neuronal and Peripheral Pentraxins Modify Glutamate Release and may Interact in Blood-Brain Barrier Failure. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 6. 2018-03-19. PMID:28334103. |
here, we confirm the presence of nptx1 around plaques in postmortem alzheimer's disease brain and report that acutely applied human nptx1 increases paired-pulse ratio at mouse ca3-ca1 hippocampal synapses, indicating a decrease in glutamate release. |
2018-03-19 |
2023-08-13 |
mouse |
| Louise Ørum Olesen, Mithula Sivasaravanaparan, Maurizio Severino, Alicia A Babcock, Elena V Bouzinova, Mark J West, Ove Wiborg, Bente Finse. Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APP Neurobiology of disease. vol 104. 2018-03-19. PMID:28461249. |
neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged app altered neurogenesis may influence hippocampal functions such as learning and memory in alzheimer's disease. |
2018-03-19 |
2023-08-13 |
mouse |
| Yi Jayne Tan, Adeline S L Ng, Ashwati Vipin, Joseph K W Lim, Russell J Chander, Fang Ji, Yingwei Qiu, Simon K S Ting, Shahul Hameed, Tih-Shih Lee, Li Zeng, Nagaendran Kandiah, Juan Zho. Higher Peripheral TREM2 mRNA Levels Relate to Cognitive Deficits and Hippocampal Atrophy in Alzheimer's Disease and Amnestic Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD. vol 58. issue 2. 2018-03-16. PMID:28453482. |
higher peripheral trem2 mrna levels relate to cognitive deficits and hippocampal atrophy in alzheimer's disease and amnestic mild cognitive impairment. |
2018-03-16 |
2023-08-13 |
Not clear |
| Yuhai Zhao, Vivian Jaber, Walter J Luki. Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus. Frontiers in cellular and infection microbiology. vol 7. 2018-03-16. PMID:28744452. |
secretory products of the human gi tract microbiome and their potential impact on alzheimer's disease (ad): detection of lipopolysaccharide (lps) in ad hippocampus. |
2018-03-16 |
2023-08-13 |
human |
| Carlos Platero, M Carmen Toba. Combining a Patch-based Approach with a Non-rigid Registration-based Label Fusion Method for the Hippocampal Segmentation in Alzheimer's Disease. Neuroinformatics. vol 15. issue 2. 2018-03-15. PMID:28132187. |
combining a patch-based approach with a non-rigid registration-based label fusion method for the hippocampal segmentation in alzheimer's disease. |
2018-03-15 |
2023-08-13 |
human |
| Carlos Platero, M Carmen Toba. Combining a Patch-based Approach with a Non-rigid Registration-based Label Fusion Method for the Hippocampal Segmentation in Alzheimer's Disease. Neuroinformatics. vol 15. issue 2. 2018-03-15. PMID:28132187. |
the method is applied for measuring the hippocampal volume, which allows discriminate between patients with alzheimer's disease (ad) or mild cognitive impairment (mci) and elderly controls (nc). |
2018-03-15 |
2023-08-13 |
human |
| Daniel Ferreira, Oskar Hansson, José Barroso, Yaiza Molina, Alejandra Machado, Juan Andrés Hernández-Cabrera, J-Sebastian Muehlboeck, Erik Stomrud, Katarina Nägga, Olof Lindberg, David Ames, Grégoria Kalpouzos, Laura Fratiglioni, Lars Bäckman, Caroline Graff, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kłoszewska, Hilkka Soininen, Simon Lovestone, Håkan Ahlström, Lars Lind, Elna-Marie Larsson, Lars-Olof Wahlund, Andrew Simmons, Eric Westma. The interactive effect of demographic and clinical factors on hippocampal volume: A multicohort study on 1958 cognitively normal individuals. Hippocampus. vol 27. issue 6. 2018-03-08. PMID:28394034. |
alzheimer's disease is characterized by hippocampal atrophy. |
2018-03-08 |
2023-08-13 |
human |
| Edward N Wilson, Andrew R Abela, Sonia Do Carmo, Simon Allard, Adam R Marks, Lindsay A Welikovitch, Adriana Ducatenzeiler, Yogita Chudasama, A Claudio Cuell. Intraneuronal Amyloid Beta Accumulation Disrupts Hippocampal CRTC1-Dependent Gene Expression and Cognitive Function in a Rat Model of Alzheimer Disease. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 2. 2018-03-06. PMID:26759481. |
intraneuronal amyloid beta accumulation disrupts hippocampal crtc1-dependent gene expression and cognitive function in a rat model of alzheimer disease. |
2018-03-06 |
2023-08-13 |
rat |