| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mortimer Mamela. Energy and the Alzheimer brain. Neuroscience and biobehavioral reviews. vol 75. 2017-10-24. PMID:28193453. |
the high energy demands of the poorly myelinated long axon hippocampal and cortical neurons render these neurons selectively vulnerable to degeneration in alzheimer's disease. |
2017-10-24 |
2023-08-13 |
mouse |
| Fei Han, Ting-Ting Zhuang, Jing-Jing Chen, Xiu-Ling Zhu, Ya-Fei Cai, Ya-Ping L. Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and RAC1/CDC42 alterations in rats. PloS one. vol 12. issue 9. 2017-10-24. PMID:28934273. |
novel derivative of paeonol, paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and rac1/cdc42 alterations in rats. |
2017-10-24 |
2023-08-13 |
rat |
| Fei Han, Ting-Ting Zhuang, Jing-Jing Chen, Xiu-Ling Zhu, Ya-Fei Cai, Ya-Ping L. Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and RAC1/CDC42 alterations in rats. PloS one. vol 12. issue 9. 2017-10-24. PMID:28934273. |
alzheimer's disease (ad) is a typical hippocampal amnesia and the most common senile dementia. |
2017-10-24 |
2023-08-13 |
rat |
| Bernard J Hanseeuw, Aaron P Schultz, Rebecca A Betensky, Reisa A Sperling, Keith A Johnso. Decreased hippocampal metabolism in high-amyloid mild cognitive impairment. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 12. issue 12. 2017-10-23. PMID:27421609. |
as hippocampus is a key region in alzheimer's disease, we hypothesized that hm is specifically decreased in high-amyloid mci. |
2017-10-23 |
2023-08-13 |
Not clear |
| Keith A Josephs, Dennis W Dickson, Nirubol Tosakulwong, Stephen D Weigand, Melissa E Murray, Leonard Petrucelli, Amanda M Liesinger, Matthew L Senjem, Anthony J Spychalla, David S Knopman, Joseph E Parisi, Ronald C Petersen, Clifford R Jack, Jennifer L Whitwel. Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study. The Lancet. Neurology. vol 16. issue 11. 2017-10-20. PMID:28919059. |
rates of hippocampal atrophy and presence of post-mortem tdp-43 in patients with alzheimer's disease: a longitudinal retrospective study. |
2017-10-20 |
2023-08-13 |
Not clear |
| Keith A Josephs, Dennis W Dickson, Nirubol Tosakulwong, Stephen D Weigand, Melissa E Murray, Leonard Petrucelli, Amanda M Liesinger, Matthew L Senjem, Anthony J Spychalla, David S Knopman, Joseph E Parisi, Ronald C Petersen, Clifford R Jack, Jennifer L Whitwel. Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study. The Lancet. Neurology. vol 16. issue 11. 2017-10-20. PMID:28919059. |
post-mortem studies have not identified an association between β-amyloid or tau and rates of hippocampal atrophy in patients with alzheimer's disease. |
2017-10-20 |
2023-08-13 |
Not clear |
| Jingyi Liang, Don Kulasiri, Sandhya Samarasingh. Computational investigation of Amyloid-β-induced location- and subunit-specific disturbances of NMDAR at hippocampal dendritic spine in Alzheimer's disease. PloS one. vol 12. issue 8. 2017-10-19. PMID:28837653. |
computational investigation of amyloid-β-induced location- and subunit-specific disturbances of nmdar at hippocampal dendritic spine in alzheimer's disease. |
2017-10-19 |
2023-08-13 |
Not clear |
| T P Tanpitukpongse, M A Mazurowski, J Ikhena, J R Petrell. Predictive Utility of Marketed Volumetric Software Tools in Subjects at Risk for Alzheimer Disease: Do Regions Outside the Hippocampus Matter? AJNR. American journal of neuroradiology. vol 38. issue 3. 2017-10-18. PMID:28057634. |
predictive utility of marketed volumetric software tools in subjects at risk for alzheimer disease: do regions outside the hippocampus matter? |
2017-10-18 |
2023-08-13 |
human |
| Nasir Mirza, Richard Appleton, Sasha Burn, Daniel du Plessis, Roderick Duncan, Jibril Osman Farah, Bjarke Feenstra, Anders Hviid, Vivek Josan, Rajiv Mohanraj, Arif Shukralla, Graeme J Sills, Anthony G Marson, Munir Pirmohame. Genetic regulation of gene expression in the epileptic human hippocampus. Human molecular genetics. vol 26. issue 9. 2017-10-17. PMID:28334860. |
in contrast, gwas meta-analyses of two other brain diseases associated with hippocampal pathology (alzheimer's disease and schizophrenia) are more enriched with normal hippocampal eqtls than with epilepsy-eqtls. |
2017-10-17 |
2023-08-13 |
human |
| Wei Lu, Shu Yang, Lei Zhang, Lin Chen, Feng-Lei Chao, Yan-Min Luo, Qian Xiao, Heng-Wei Gu, Rong Jiang, Yong Tan. Decreased Myelinated Fibers in the Hippocampal Dentate Gyrus of the Tg2576 Mouse Model of Alzheimer's Disease. Current Alzheimer research. vol 13. issue 9. 2017-10-16. PMID:26971933. |
decreased myelinated fibers in the hippocampal dentate gyrus of the tg2576 mouse model of alzheimer's disease. |
2017-10-16 |
2023-08-13 |
mouse |
| Yu Zhang, Long-Jian Huang, Si Shi, Shao-Feng Xu, Xiao-Liang Wang, Ying Pen. L-3-n-butylphthalide Rescues Hippocampal Synaptic Failure and Attenuates Neuropathology in Aged APP/PS1 Mouse Model of Alzheimer's Disease. CNS neuroscience & therapeutics. vol 22. issue 12. 2017-10-16. PMID:27439966. |
l-3-n-butylphthalide rescues hippocampal synaptic failure and attenuates neuropathology in aged app/ps1 mouse model of alzheimer's disease. |
2017-10-16 |
2023-08-13 |
mouse |
| Xiaoying Tang, Vijay R Varma, Michael I Miller, Michelle C Carlso. Education is associated with sub-regions of the hippocampus and the amygdala vulnerable to neuropathologies of Alzheimer's disease. Brain structure & function. vol 222. issue 3. 2017-10-16. PMID:27535407. |
education is associated with sub-regions of the hippocampus and the amygdala vulnerable to neuropathologies of alzheimer's disease. |
2017-10-16 |
2023-08-13 |
Not clear |
| Bruce A Berkowitz, Jacob Lenning, Nikita Khetarpal, Catherine Tran, Johnny Y Wu, Ali M Berri, Kristin Dernay, E Mark Haacke, Fatema Shafie-Khorassani, Robert H Podolsky, John C Gant, Shaniya Maimaiti, Olivier Thibault, Geoffrey G Murphy, Brian M Bennett, Robin Robert. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 9. 2017-10-13. PMID:28592637. |
hippocampus oxidative stress is considered pathogenic in neurodegenerative diseases, such as alzheimer disease (ad), and in neurodevelopmental disorders, such as angelman syndrome (as). |
2017-10-13 |
2023-08-13 |
Not clear |
| Willem de Haan, Elisabeth C W van Straaten, Alida A Gouw, Cornelis J Sta. Altering neuronal excitability to preserve network connectivity in a computational model of Alzheimer's disease. PLoS computational biology. vol 13. issue 9. 2017-10-13. PMID:28938009. |
neuronal hyperactivity and hyperexcitability of the cerebral cortex and hippocampal region is an increasingly observed phenomenon in preclinical alzheimer's disease (ad). |
2017-10-13 |
2023-08-13 |
human |
| Paul K Crane, Rod L Walker, Joshua Sonnen, Laura E Gibbons, Rebecca Melrose, Jason Hassenstab, C Dirk Keene, Nadia Postupna, Thomas J Montine, Eric B Larso. Glucose levels during life and neuropathologic findings at autopsy among people never treated for diabetes. Neurobiology of aging. vol 48. 2017-10-12. PMID:27644076. |
autopsy evaluations included braak stage for neurofibrillary tangles, consortium to establish a registry for alzheimer's disease grade for neuritic plaques, macroscopic infarcts including lacunar infarcts, lewy bodies, cerebral microinfarcts, and hippocampal sclerosis. |
2017-10-12 |
2023-08-13 |
Not clear |
| David J Braun, Sergey Kalinin, Douglas L Feinstei. Conditional Depletion of Hippocampal Brain-Derived Neurotrophic Factor Exacerbates Neuropathology in a Mouse Model of Alzheimer's Disease. ASN neuro. vol 9. issue 2. 2017-10-12. PMID:28266222. |
conditional depletion of hippocampal brain-derived neurotrophic factor exacerbates neuropathology in a mouse model of alzheimer's disease. |
2017-10-12 |
2023-08-13 |
mouse |
| Keith S Cover, Ronald A van Schijndel, Adriaan Versteeg, Kelvin K Leung, Emma R Mulder, Remko A Jong, Peter J Visser, Alberto Redolfi, Jerome Revillard, Baptiste Grenier, David Manset, Soheil Damangir, Paolo Bosco, Hugo Vrenken, Bob W van Dijk, Giovanni B Frisoni, Frederik Barkho. Reproducibility of hippocampal atrophy rates measured with manual, FreeSurfer, AdaBoost, FSL/FIRST and the MAPS-HBSI methods in Alzheimer's disease. Psychiatry research. Neuroimaging. vol 252. 2017-10-10. PMID:27179313. |
reproducibility of hippocampal atrophy rates measured with manual, freesurfer, adaboost, fsl/first and the maps-hbsi methods in alzheimer's disease. |
2017-10-10 |
2023-08-13 |
human |
| Keith S Cover, Ronald A van Schijndel, Adriaan Versteeg, Kelvin K Leung, Emma R Mulder, Remko A Jong, Peter J Visser, Alberto Redolfi, Jerome Revillard, Baptiste Grenier, David Manset, Soheil Damangir, Paolo Bosco, Hugo Vrenken, Bob W van Dijk, Giovanni B Frisoni, Frederik Barkho. Reproducibility of hippocampal atrophy rates measured with manual, FreeSurfer, AdaBoost, FSL/FIRST and the MAPS-HBSI methods in Alzheimer's disease. Psychiatry research. Neuroimaging. vol 252. 2017-10-10. PMID:27179313. |
the purpose of this study is to assess the reproducibility of hippocampal atrophy rate measurements of commonly used fully-automated algorithms in alzheimer disease (ad). |
2017-10-10 |
2023-08-13 |
human |
| A C Pereira, J D Gray, J F Kogan, R L Davidson, T G Rubin, M Okamoto, J H Morrison, B S McEwe. Age and Alzheimer's disease gene expression profiles reversed by the glutamate modulator riluzole. Molecular psychiatry. vol 22. issue 2. 2017-10-03. PMID:27021815. |
alzheimer's disease (ad) and age-related cognitive decline represent a growing health burden and involve the hippocampus, a vulnerable brain region implicated in learning and memory. |
2017-10-03 |
2023-08-13 |
human |
| David C Hondius, Pim van Nierop, Ka Wan Li, Jeroen J M Hoozemans, Roel C van der Schors, Elise S van Haastert, Saskia M van der Vies, Annemieke J M Rozemuller, August B Smi. Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 12. issue 6. 2017-10-02. PMID:26772638. |
we performed a comprehensive quantitative proteomics study on human hippocampus tissue involving all braak stages to assess changes in protein abundance over the various stages of alzheimer's disease (ad). |
2017-10-02 |
2023-08-13 |
human |