| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paul K Crane, Rod L Walker, Joshua Sonnen, Laura E Gibbons, Rebecca Melrose, Jason Hassenstab, C Dirk Keene, Nadia Postupna, Thomas J Montine, Eric B Larso. Glucose levels during life and neuropathologic findings at autopsy among people never treated for diabetes. Neurobiology of aging. vol 48. 2017-10-12. PMID:27644076. |
autopsy evaluations included braak stage for neurofibrillary tangles, consortium to establish a registry for alzheimer's disease grade for neuritic plaques, macroscopic infarcts including lacunar infarcts, lewy bodies, cerebral microinfarcts, and hippocampal sclerosis. |
2017-10-12 |
2023-08-13 |
Not clear |
| David J Braun, Sergey Kalinin, Douglas L Feinstei. Conditional Depletion of Hippocampal Brain-Derived Neurotrophic Factor Exacerbates Neuropathology in a Mouse Model of Alzheimer's Disease. ASN neuro. vol 9. issue 2. 2017-10-12. PMID:28266222. |
conditional depletion of hippocampal brain-derived neurotrophic factor exacerbates neuropathology in a mouse model of alzheimer's disease. |
2017-10-12 |
2023-08-13 |
mouse |
| Keith S Cover, Ronald A van Schijndel, Adriaan Versteeg, Kelvin K Leung, Emma R Mulder, Remko A Jong, Peter J Visser, Alberto Redolfi, Jerome Revillard, Baptiste Grenier, David Manset, Soheil Damangir, Paolo Bosco, Hugo Vrenken, Bob W van Dijk, Giovanni B Frisoni, Frederik Barkho. Reproducibility of hippocampal atrophy rates measured with manual, FreeSurfer, AdaBoost, FSL/FIRST and the MAPS-HBSI methods in Alzheimer's disease. Psychiatry research. Neuroimaging. vol 252. 2017-10-10. PMID:27179313. |
reproducibility of hippocampal atrophy rates measured with manual, freesurfer, adaboost, fsl/first and the maps-hbsi methods in alzheimer's disease. |
2017-10-10 |
2023-08-13 |
human |
| Keith S Cover, Ronald A van Schijndel, Adriaan Versteeg, Kelvin K Leung, Emma R Mulder, Remko A Jong, Peter J Visser, Alberto Redolfi, Jerome Revillard, Baptiste Grenier, David Manset, Soheil Damangir, Paolo Bosco, Hugo Vrenken, Bob W van Dijk, Giovanni B Frisoni, Frederik Barkho. Reproducibility of hippocampal atrophy rates measured with manual, FreeSurfer, AdaBoost, FSL/FIRST and the MAPS-HBSI methods in Alzheimer's disease. Psychiatry research. Neuroimaging. vol 252. 2017-10-10. PMID:27179313. |
the purpose of this study is to assess the reproducibility of hippocampal atrophy rate measurements of commonly used fully-automated algorithms in alzheimer disease (ad). |
2017-10-10 |
2023-08-13 |
human |
| A C Pereira, J D Gray, J F Kogan, R L Davidson, T G Rubin, M Okamoto, J H Morrison, B S McEwe. Age and Alzheimer's disease gene expression profiles reversed by the glutamate modulator riluzole. Molecular psychiatry. vol 22. issue 2. 2017-10-03. PMID:27021815. |
alzheimer's disease (ad) and age-related cognitive decline represent a growing health burden and involve the hippocampus, a vulnerable brain region implicated in learning and memory. |
2017-10-03 |
2023-08-13 |
human |
| David C Hondius, Pim van Nierop, Ka Wan Li, Jeroen J M Hoozemans, Roel C van der Schors, Elise S van Haastert, Saskia M van der Vies, Annemieke J M Rozemuller, August B Smi. Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 12. issue 6. 2017-10-02. PMID:26772638. |
we performed a comprehensive quantitative proteomics study on human hippocampus tissue involving all braak stages to assess changes in protein abundance over the various stages of alzheimer's disease (ad). |
2017-10-02 |
2023-08-13 |
human |
| Yuko Hara, Yumiko Motoi, Keigo Hikishima, Hiroshi Mizuma, Hirotaka Onoe, Shin-Ei Matsumoto, Montasir Elahi, Hideyuki Okano, Shigeki Aoki, Nobutaka Hattor. Involvement of the Septo-Hippocampal Cholinergic Pathway in Association with Septal Acetylcholinesterase Upregulation in a Mouse Model of Tauopathy. Current Alzheimer research. vol 14. issue 1. 2017-10-02. PMID:27335039. |
cholinergic cell loss in the basal forebrain, the major source of hippocampal cholinergic projections, has been implicated in alzheimer's disease. |
2017-10-02 |
2023-08-13 |
mouse |
| Farzaneh Rostami, Mohammad Javan, Ali Moghimi, Aliakbar Haddad-Mashadrizeh, Masoud Fereidon. Streptozotocin-induced hippocampal astrogliosis and insulin signaling malfunction as experimental scales for subclinical sporadic Alzheimer model. Life sciences. vol 188. 2017-09-29. PMID:28867578. |
streptozotocin-induced hippocampal astrogliosis and insulin signaling malfunction as experimental scales for subclinical sporadic alzheimer model. |
2017-09-29 |
2023-08-13 |
rat |
| Anupam Hazra, Brian F Corbett, Jason C You, Suzan Aschmies, Lijuan Zhao, Ke Li, Angelo C Lepore, Eric D Marsh, Jeannie Chi. Corticothalamic network dysfunction and behavioral deficits in a mouse model of Alzheimer's disease. Neurobiology of aging. vol 44. 2017-09-28. PMID:27318137. |
finally, the severity of sleep impairments predicted the severity of deficits in morris water maze, suggesting corticothalamic dysfunction may relate to hippocampal dysfunction, and may be a pathophysiological mechanism underlying multiple behavioral and cognitive alterations in alzheimer's disease. |
2017-09-28 |
2023-08-13 |
mouse |
| David S Knopman, Clifford R Jack, Emily S Lundt, Stephen D Weigand, Prashanthi Vemuri, Val J Lowe, Kejal Kantarci, Jeffrey L Gunter, Matthew L Senjem, Michelle M Mielke, Mary M Machulda, Rosebud O Roberts, Bradley F Boeve, David T Jones, Ronald C Peterse. Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum. Neurobiology of aging. vol 46. 2017-09-28. PMID:27460147. |
pittsburgh compound b (pib) positron emission tomography (pet) was used to select participants in the mayo clinic study of aging and the mayo alzheimer's disease research center with elevated β-amyloid, designated as "a+," and hippocampal volume and (18)fluorodeoxyglucose (fdg) positron emission tomography were used to characterize participants as having evidence of neurodegeneration ("n+") at the baseline evaluation. |
2017-09-28 |
2023-08-13 |
human |
| Cândida Dias, Cátia F Lourenço, Elisabete Ferreiro, Rui M Barbosa, João Laranjinha, Ana Led. Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiology of aging. vol 46. 2017-09-28. PMID:27460153. |
age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of alzheimer's disease: implications for neurometabolic regulation. |
2017-09-28 |
2023-08-13 |
mouse |
| Aram Asatryan, Nicolas G Baza. Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection. The Journal of biological chemistry. vol 292. issue 30. 2017-09-26. PMID:28615451. |
docosanoids include neuroprotectin d1 (npd1), which is decreased in the ca1 hippocampal area of patients with early-stage alzheimer's disease (ad). |
2017-09-26 |
2023-08-13 |
Not clear |
| Matthew D Cykowski, Suzanne Z Powell, Paul E Schulz, Hidehiro Takei, Andreana L Rivera, Robert E Jackson, Gustavo Roman, Gregory A Jicha, Peter T Nelso. Hippocampal Sclerosis in Older Patients: Practical Examples and Guidance With a Focus on Cerebral Age-Related TDP-43 With Sclerosis. Archives of pathology & laboratory medicine. vol 141. issue 8. 2017-09-25. PMID:28467211. |
hippocampal sclerosis may also be comorbid with frontotemporal lobar degeneration, alzheimer disease, and lewy body disease. |
2017-09-25 |
2023-08-13 |
Not clear |
| Christoph Köhle. Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology. Acta neuropathologica. vol 132. issue 3. 2017-09-22. PMID:27062260. |
granule-containing vacuoles in the cytoplasm of hippocampal neurons are a neuropathological feature of alzheimer's disease. |
2017-09-22 |
2023-08-13 |
Not clear |
| Christoph Köhle. Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology. Acta neuropathologica. vol 132. issue 3. 2017-09-22. PMID:27062260. |
however, several studies have reported much higher numbers of neurons undergoing gvd in the hippocampus of alzheimer's disease cases. |
2017-09-22 |
2023-08-13 |
Not clear |
| Alexandra M Nicholson, Rosa Rademaker. What we know about TMEM106B in neurodegeneration. Acta neuropathologica. vol 132. issue 5. 2017-09-20. PMID:27543298. |
in this manuscript, we review the initial discovery and replication studies describing tmem106b variants as disease risk factors and modifiers in tdp-43 proteinopathies, such as ftld-tdp caused by progranulin (grn) or chromosome 9 open reading frame 72 (c9orf72) mutations, as well as alzheimer's disease and hippocampal sclerosis. |
2017-09-20 |
2023-08-13 |
Not clear |
| Elisabeth Sanchez-Mejias, Victoria Navarro, Sebastian Jimenez, Maria Sanchez-Mico, Raquel Sanchez-Varo, Cristina Nuñez-Diaz, Laura Trujillo-Estrada, Jose Carlos Davila, Marisa Vizuete, Antonia Gutierrez, Javier Vitoric. Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration. Acta neuropathologica. vol 132. issue 6. 2017-09-20. PMID:27743026. |
soluble phospho-tau from alzheimer's disease hippocampus drives microglial degeneration. |
2017-09-20 |
2023-08-13 |
human |
| Peter T Nelson, Yuriko Katsumata, Kwangsik Nho, Sergey C Artiushin, Gregory A Jicha, Wang-Xia Wang, Erin L Abner, Andrew J Saykin, Walter A Kukull, David W Fard. Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging. Acta neuropathologica. vol 132. issue 6. 2017-09-20. PMID:27815632. |
we found that the rs73069071 risk genotype was associated with hippocampal sclerosis (hs) pathology among people with the rs704180 risk genotype (national alzheimer's coordinating center/alzheimer's disease genetic consortium data; n = 2113, including 241 autopsy-confirmed hs cases). |
2017-09-20 |
2023-08-13 |
human |
| Helen Ling, Huw R Morris, James W Neal, Andrew J Lees, John Hardy, Janice L Holton, Tamas Revesz, David D R William. Mixed pathologies including chronic traumatic encephalopathy account for dementia in retired association football (soccer) players. Acta neuropathologica. vol 133. issue 3. 2017-09-20. PMID:28205009. |
four cases had pathologically confirmed cte; concomitant pathologies included alzheimer's disease (n = 6), tdp-43 (n = 6), cerebral amyloid angiopathy (n = 5), hippocampal sclerosis (n = 2), corticobasal degeneration (n = 1), dementia with lewy bodies (n = 1), and vascular pathology (n = 1); and all would have contributed synergistically to the clinical manifestations. |
2017-09-20 |
2023-08-13 |
human |
| Stephen W Scheff, Mubeen A Ansari, Elliott J Mufso. Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer's disease pathology. Neurobiology of aging. vol 42. 2017-09-19. PMID:27143416. |
oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with alzheimer's disease pathology. |
2017-09-19 |
2023-08-13 |
human |