| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katherine A Price, Merina Varghese, Allison Sowa, Frank Yuk, Hannah Brautigam, Michelle E Ehrlich, Dara L Dickstei. Altered synaptic structure in the hippocampus in a mouse model of Alzheimer's disease with soluble amyloid-β oligomers and no plaque pathology. Molecular neurodegeneration. vol 9. 2015-03-30. PMID:25312309. |
altered synaptic structure in the hippocampus in a mouse model of alzheimer's disease with soluble amyloid-β oligomers and no plaque pathology. |
2015-03-30 |
2023-08-13 |
mouse |
| Jing Jiang, Kai Gao, Yuan Zhou, Anping Xu, Suhua Shi, Gang Liu, Zhigang L. Electroacupuncture Treatment Improves Learning-Memory Ability and Brain Glucose Metabolism in a Mouse Model of Alzheimer's Disease: Using Morris Water Maze and Micro-PET. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-03-30. PMID:25821477. |
alzheimer's disease (ad) causes progressive hippocampus dysfunctions leading to the impairment of learning and memory ability and low level of uptake rate of glucose in hippocampus. |
2015-03-30 |
2023-08-13 |
mouse |
| Ying Liu, Jin-Tai Yu, Hui-Fu Wang, Pei-Ran Han, Chen-Chen Tan, Chong Wang, Xiang-Fei Meng, Shannon L Risacher, Andrew J Saykin, Lan Ta. APOE genotype and neuroimaging markers of Alzheimer's disease: systematic review and meta-analysis. Journal of neurology, neurosurgery, and psychiatry. vol 86. issue 2. 2015-03-27. PMID:24838911. |
we aimed to examine the association of apolipoprotein e (apoe) ɛ4 genotype with neuroimaging markers of alzheimer's disease: hippocampal volume, brain amyloid deposition and cerebral metabolism. |
2015-03-27 |
2023-08-13 |
Not clear |
| Ping Zhang, Gangyong Zhao, Xianjiang Kang, Likai S. Effects of lateral ventricular transplantation of bone marrow-derived mesenchymal stem cells modified with brain-derived neurotrophic factor gene on cognition in a rat model of Alzheimer's disease. Neural regeneration research. vol 7. issue 4. 2015-03-25. PMID:25806063. |
results indicate that transplantation of bone marrow-derived mesenchymal stem cells modified with brain-derived neurotrophic factor gene can significantly improve cognitive function in a rat model of alzheimer's disease, possibly by increasing the levels of brain-derived neurotrophic factor and tyrosine kinase b in the hippocampus. |
2015-03-25 |
2023-08-13 |
rat |
| Kevin Richetin, Clémence Leclerc, Nicolas Toni, Thierry Gallopin, Stéphane Pech, Laurent Roybon, Claire Rampo. Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease. Brain : a journal of neurology. vol 138. issue Pt 2. 2015-03-23. PMID:25518958. |
genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of alzheimer's disease. |
2015-03-23 |
2023-08-13 |
mouse |
| Kevin Richetin, Clémence Leclerc, Nicolas Toni, Thierry Gallopin, Stéphane Pech, Laurent Roybon, Claire Rampo. Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease. Brain : a journal of neurology. vol 138. issue Pt 2. 2015-03-23. PMID:25518958. |
when tested in an appxps1 mouse model of alzheimer's disease, directed expression of neurod1 in cycling hippocampal progenitors conspicuously reduced dendritic spine density deficits on new hippocampal neurons, to the same level as that observed in healthy age-matched control animals. |
2015-03-23 |
2023-08-13 |
mouse |
| Holly C Hunsberger, Carolyn C Rudy, Seth R Batten, Greg A Gerhardt, Miranda N Ree. P301L tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway. Journal of neurochemistry. vol 132. issue 2. 2015-03-16. PMID:25319522. |
individuals at risk of developing alzheimer's disease (ad) often exhibit hippocampal hyperexcitability. |
2015-03-16 |
2023-08-13 |
mouse |
| Yinghong Li, Zhengzhi Wu, Yu Jin, Anmin Wu, Meiqun Cao, Kehuan Sun, Xiuqin Jia, Manyin Che. Analysis of hippocampal gene expression profile of Alzheimer's disease model rats using genome chip bioinformatics. Neural regeneration research. vol 7. issue 5. 2015-03-16. PMID:25774171. |
analysis of hippocampal gene expression profile of alzheimer's disease model rats using genome chip bioinformatics. |
2015-03-16 |
2023-08-13 |
rat |
| Yinghong Li, Zhengzhi Wu, Yu Jin, Anmin Wu, Meiqun Cao, Kehuan Sun, Xiuqin Jia, Manyin Che. Analysis of hippocampal gene expression profile of Alzheimer's disease model rats using genome chip bioinformatics. Neural regeneration research. vol 7. issue 5. 2015-03-16. PMID:25774171. |
in this study, an alzheimer's disease model was established in rats through stereotactic injection of condensed amyloid beta 1-40 into the bilateral hippocampus, and the changes of gene expression profile in the hippocampus of rat models and sham-operated rats were compared by genome expression profiling analysis. |
2015-03-16 |
2023-08-13 |
rat |
| Yinghong Li, Zhengzhi Wu, Yu Jin, Anmin Wu, Meiqun Cao, Kehuan Sun, Xiuqin Jia, Manyin Che. Analysis of hippocampal gene expression profile of Alzheimer's disease model rats using genome chip bioinformatics. Neural regeneration research. vol 7. issue 5. 2015-03-16. PMID:25774171. |
results showed that the expression of 50 genes was significantly up-regulated (fold change ≥ 2), while 21 genes were significantly down-regulated in the hippocampus of alzheimer's disease model rats (fold change ≤ 0.5) compared with the sham-operation group. |
2015-03-16 |
2023-08-13 |
rat |
| Yinghong Li, Zhengzhi Wu, Yu Jin, Anmin Wu, Meiqun Cao, Kehuan Sun, Xiuqin Jia, Manyin Che. Analysis of hippocampal gene expression profile of Alzheimer's disease model rats using genome chip bioinformatics. Neural regeneration research. vol 7. issue 5. 2015-03-16. PMID:25774171. |
our findings indicate that several genes were abnormally expressed in the metabolic and signal transduction pathways in the hippocampus of amyloid beta 1-40-induced rat model of alzheimer's disease, thereby affecting the hippocampal and brain functions. |
2015-03-16 |
2023-08-13 |
rat |
| J C Gant, E M Blalock, K-C Chen, I Kadish, N M Porter, C M Norris, O Thibault, P W Landfiel. FK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation? European journal of pharmacology. vol 739. 2015-03-13. PMID:24291098. |
moreover, in microarray studies, we found fkbp1b gene expression was downregulated in hippocampus of aging rats and early-stage alzheimer's disease subjects. |
2015-03-13 |
2023-08-12 |
human |
| Davide Vito Morett. Electroencephalography reveals lower regional blood perfusion and atrophy of the temporoparietal network associated with memory deficits and hippocampal volume reduction in mild cognitive impairment due to Alzheimer's disease. Neuropsychiatric disease and treatment. vol 11. 2015-03-09. PMID:25750526. |
electroencephalography reveals lower regional blood perfusion and atrophy of the temporoparietal network associated with memory deficits and hippocampal volume reduction in mild cognitive impairment due to alzheimer's disease. |
2015-03-09 |
2023-08-13 |
human |
| Davide Vito Morett. Electroencephalography reveals lower regional blood perfusion and atrophy of the temporoparietal network associated with memory deficits and hippocampal volume reduction in mild cognitive impairment due to Alzheimer's disease. Neuropsychiatric disease and treatment. vol 11. 2015-03-09. PMID:25750526. |
an increased electroencephalographic (eeg) upper/lower alpha power ratio has been associated with less regional blood perfusion, atrophy of the temporoparietal region of the brain, and reduction of hippocampal volume in subjects affected by mild cognitive impairment due to alzheimer's disease as compared with subjects who do not develop the disease. |
2015-03-09 |
2023-08-13 |
human |
| Min Chen, Jing Wang, Cairong Min. Buyuan Congnao decoction decreases hippocampal beta-amyloid expression in a rat model of Alzheimer's disease. Neural regeneration research. vol 7. issue 9. 2015-03-06. PMID:25745460. |
buyuan congnao decoction decreases hippocampal beta-amyloid expression in a rat model of alzheimer's disease. |
2015-03-06 |
2023-08-13 |
rat |
| Min Chen, Jing Wang, Cairong Min. Buyuan Congnao decoction decreases hippocampal beta-amyloid expression in a rat model of Alzheimer's disease. Neural regeneration research. vol 7. issue 9. 2015-03-06. PMID:25745460. |
a mixture of ibotenic acid and β-amyloid 1-42 was injected into the hippocampus of a rat model of alzheimer's disease, followed by intragastric administration of a traditional chinese medicine buyuan congnao decoction (main components included radix astragali, radix polygoni multiflori preparata, rhizoma acori talarinowii, radix polygalae, fructus alpiniae oxyphyllae, and radix glycyrrhizae preparata) and a piracetam suspension. |
2015-03-06 |
2023-08-13 |
rat |
| Min Chen, Jing Wang, Cairong Min. Buyuan Congnao decoction decreases hippocampal beta-amyloid expression in a rat model of Alzheimer's disease. Neural regeneration research. vol 7. issue 9. 2015-03-06. PMID:25745460. |
these findings suggested that compound prescription of buyuan congnao decoction, similar to the curative effects of piracetam, decreased hippocampal β-amyloid expression in a rat model of alzheimer's disease, as well as improved learning and memory. |
2015-03-06 |
2023-08-13 |
rat |
| Kate E Macdonald, Kelvin K Leung, Jonathan W Bartlett, Melanie Blair, Ian B Malone, Josephine Barnes, Sebastien Ourselin, Nick C Fo. Automated template-based hippocampal segmentations from MRI: the effects of 1.5T or 3T field strength on accuracy. Neuroinformatics. vol 12. issue 3. 2015-03-02. PMID:24395058. |
hippocampal volumetric measures may be useful for alzheimer's disease (ad) diagnosis and disease tracking; however, manual segmentation of the hippocampus is labour-intensive. |
2015-03-02 |
2023-08-12 |
Not clear |
| Jie Shi, Natasha Leporé, Boris A Gutman, Paul M Thompson, Leslie C Baxter, Richard J Caselli, Yalin Wan. Genetic influence of apolipoprotein E4 genotype on hippocampal morphometry: An N = 725 surface-based Alzheimer's disease neuroimaging initiative study. Human brain mapping. vol 35. issue 8. 2015-02-27. PMID:24453132. |
genetic influence of apolipoprotein e4 genotype on hippocampal morphometry: an n = 725 surface-based alzheimer's disease neuroimaging initiative study. |
2015-02-27 |
2023-08-12 |
human |
| Jie Shi, Natasha Leporé, Boris A Gutman, Paul M Thompson, Leslie C Baxter, Richard J Caselli, Yalin Wan. Genetic influence of apolipoprotein E4 genotype on hippocampal morphometry: An N = 725 surface-based Alzheimer's disease neuroimaging initiative study. Human brain mapping. vol 35. issue 8. 2015-02-27. PMID:24453132. |
here we examined the effect of apoe e4 on hippocampal morphometry in a large imaging database-the alzheimer's disease neuroimaging initiative (adni). |
2015-02-27 |
2023-08-12 |
human |