All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
Markus Donix, Alison C Burggren, Maria Scharf, Kira Marschner, Nanthia A Suthana, Prabha Siddarth, Allison K Krupa, Michael Jones, Laurel Martin-Harris, Linda M Ercoli, Karen J Miller, Annett Werner, Rüdiger von Kummer, Cathrin Sauer, Gary W Small, Vjera A Holthoff, Susan Y Bookheime. APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease. Psychiatry research. vol 214. issue 3. 2014-10-10. PMID:24080518. furthermore, entorhinal and hippocampal hemispheric asymmetry could be modified by pathology during alzheimer's disease development. 2014-10-10 2023-08-12 human
Markus Donix, Alison C Burggren, Maria Scharf, Kira Marschner, Nanthia A Suthana, Prabha Siddarth, Allison K Krupa, Michael Jones, Laurel Martin-Harris, Linda M Ercoli, Karen J Miller, Annett Werner, Rüdiger von Kummer, Cathrin Sauer, Gary W Small, Vjera A Holthoff, Susan Y Bookheime. APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease. Psychiatry research. vol 214. issue 3. 2014-10-10. PMID:24080518. using high-resolution magnetic resonance imaging and a cortical unfolding technique we investigated whether carrying the apoe-4 allele influences hemispheric asymmetry in the entorhinal cortex and the hippocampus among patients with alzheimer's disease as well as in middle-aged and older cognitively healthy individuals. 2014-10-10 2023-08-12 human
Juan Beauquis, Angeles Vinuesa, Carlos Pomilio, Patricio Pavía, Verónica Galván, Flavia Saravi. Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease. Hippocampus. vol 24. issue 3. 2014-10-07. PMID:24132937. neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in pdapp mice, model of alzheimer's disease. 2014-10-07 2023-08-12 mouse
Juan Beauquis, Angeles Vinuesa, Carlos Pomilio, Patricio Pavía, Verónica Galván, Flavia Saravi. Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease. Hippocampus. vol 24. issue 3. 2014-10-07. PMID:24132937. in the context of alzheimer's disease (ad), hippocampal alterations have been well described in advanced stages of the pathology, when amyloid deposition, inflammation and glial activation occur, but less attention has been directed to studying early brain and behavioral changes. 2014-10-07 2023-08-12 mouse
L H Nilsen, T M Melø, M P Witter, U Sonnewal. Early differences in dorsal hippocampal metabolite levels in males but not females in a transgenic rat model of Alzheimer's disease. Neurochemical research. vol 39. issue 2. 2014-10-07. PMID:24338370. early differences in dorsal hippocampal metabolite levels in males but not females in a transgenic rat model of alzheimer's disease. 2014-10-07 2023-08-12 human
L H Nilsen, T M Melø, M P Witter, U Sonnewal. Early differences in dorsal hippocampal metabolite levels in males but not females in a transgenic rat model of Alzheimer's disease. Neurochemical research. vol 39. issue 2. 2014-10-07. PMID:24338370. the results from this preliminary study demonstrate early metabolite alterations in the dorsal hippocampus of males in this rat model of alzheimer's disease, and imply that very early possible neurochemical markers of the disease are different for males and females. 2014-10-07 2023-08-12 human
Patricia Facchinetti, Emilie Dorard, Vincent Contremoulins, Marie-Claude Gaillard, Nicole Déglon, Véronique Sazdovitch, Chantal Guihenneuc-Jouyaux, Emmanuel Brouillet, Charles Duyckaerts, Bernadette Allinquan. SET translocation is associated with increase in caspase cleaved amyloid precursor protein in CA1 of Alzheimer and Down syndrome patients. Neurobiology of aging. vol 35. issue 5. 2014-10-06. PMID:24262202. to elucidate the putative relationships between mislocalized appcc and set, we studied their level and distribution in the hippocampus of 5 controls, 3 down syndrome and 10 alzheimer patients. 2014-10-06 2023-08-12 mouse
Willa D Brenowitz, Sarah E Monsell, Frederick A Schmitt, Walter A Kukull, Peter T Nelso. Hippocampal sclerosis of aging is a key Alzheimer's disease mimic: clinical-pathologic correlations and comparisons with both alzheimer's disease and non-tauopathic frontotemporal lobar degeneration. Journal of Alzheimer's disease : JAD. vol 39. issue 3. 2014-10-06. PMID:24270205. hippocampal sclerosis of aging is a key alzheimer's disease mimic: clinical-pathologic correlations and comparisons with both alzheimer's disease and non-tauopathic frontotemporal lobar degeneration. 2014-10-06 2023-08-12 human
Tytus Murphy, Gisele Pereira Dias, Sandrine Thure. Effects of diet on brain plasticity in animal and human studies: mind the gap. Neural plasticity. vol 2014. 2014-10-06. PMID:24900924. in particular, we evaluate the gap in mechanistic understanding between recent findings from animal studies and those human studies reporting that these dietary factors can benefit cognition, mood, and anxiety, aging, and alzheimer's disease-with focus on the enhancement of structural and functional plasticity markers in the hippocampus, such as increased expression of neurotrophic factors, synaptic function and adult neurogenesis. 2014-10-06 2023-08-13 human
Irena Štěpán-Buksakowska, Nikoletta Szabó, Daniel Hořínek, Eszter Tóth, Jakub Hort, Joshua Warner, František Charvát, László Vécsei, Miloslav Roček, Zsigmond T Kincse. Cortical and subcortical atrophy in Alzheimer disease: parallel atrophy of thalamus and hippocampus. Alzheimer disease and associated disorders. vol 28. issue 1. 2014-10-01. PMID:23751371. cortical and subcortical atrophy in alzheimer disease: parallel atrophy of thalamus and hippocampus. 2014-10-01 2023-08-12 Not clear
Jing Teng, Zhexue Xu, Jing Zhang, Jingmin L. Effect of yizhitongxuan decoction on learning and memory ability, Gaq/11 expression and Na(+)-K(+)-ATP enzyme activity in rat models of Alzheimer's disease. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 34. issue 4. 2014-09-30. PMID:25185367. to study the effects of yizhitongxuan decoction on learning and memory abilities, gaq/11 expression and na(+)-k(+)-atp enzyme activity in rat models of alzheimer's disease (ad) caused by injecting abeta25-35 into the hippocampus. 2014-09-30 2023-08-13 rat
Fernando J Sepúlveda, Humberto Fierro, Eduardo Fernandez, Carolina Castillo, Robert W Peoples, Carlos Opazo, Luis G Aguay. Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease. Neurobiology of aging. vol 35. issue 3. 2014-09-29. PMID:24112789. nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in alzheimer's disease. 2014-09-29 2023-08-12 Not clear
Daniela Puzzo, Carla Loreto, Salvatore Giunta, Giuseppe Musumeci, Giuseppina Frasca, Maria Vittoria Podda, Ottavio Arancio, Agostino Palmer. Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice. Neurobiology of aging. vol 35. issue 3. 2014-09-29. PMID:24112792. because it has been previously demonstrated that phosphodiesterase-5 inhibitors (pde5-is) protect against hippocampal synaptic dysfunction and memory deficits in mouse models of alzheimer's disease and physiological aging, we investigated the effect of a treatment with the pde5-i, sildenafil, on cell death, pro- and antiapoptotic molecules, and aβ production. 2014-09-29 2023-08-12 mouse
Stefan Teipel, Helmut Heinsen, Edson Amaro, Lea T Grinberg, Bernd Krause, Michel Groth. Cholinergic basal forebrain atrophy predicts amyloid burden in Alzheimer's disease. Neurobiology of aging. vol 35. issue 3. 2014-09-29. PMID:24176625. we compared accuracy of hippocampus and basal forebrain cholinergic system (bfcs) atrophy to predict cortical amyloid burden in 179 cognitively normal subjects (cn), 269 subjects with early stages of mild cognitive impairment (mci), 136 subjects with late stages of mci, and 86 subjects with alzheimer's disease (ad) dementia retrieved from the alzheimer's disease neuroimaging initiative database. 2014-09-29 2023-08-12 human
Peng Yu, Jia Sun, Robin Wolz, Diane Stephenson, James Brewer, Nick C Fox, Patricia E Cole, Clifford R Jack, Derek L G Hill, Adam J Schwar. Operationalizing hippocampal volume as an enrichment biomarker for amnestic mild cognitive impairment trials: effect of algorithm, test-retest variability, and cut point on trial cost, duration, and sample size. Neurobiology of aging. vol 35. issue 4. 2014-09-29. PMID:24211008. we evaluated the enrichment performance of 4 widely used hippocampal segmentation algorithms (freesurfer, hippocampus multi-atlas propagation and segmentation (hmaps), learning embeddings atlas propagation (leap), and neuroquant) in terms of 2-year changes in mini-mental state examination (mmse), alzheimer's disease assessment scale-cognitive subscale (adas-cog), and clinical dementia rating sum of boxes (cdr-sb). 2014-09-29 2023-08-12 human
A E Ramírez, C R Pacheco, L G Aguayo, C M Opaz. Rapamycin protects against Aβ-induced synaptotoxicity by increasing presynaptic activity in hippocampal neurons. Biochimica et biophysica acta. vol 1842. issue 9. 2014-09-25. PMID:24794719. under these conditions, rapamycin-treated hippocampal neurons are resistant to the synaptotoxic effect induced by aβ oligomers, suggesting that enhancers of presynaptic activity can be therapeutic agents for alzheimer's disease. 2014-09-25 2023-08-13 rat
Ignacio Pedrós, Dmitry Petrov, Michael Allgaier, Francesc Sureda, Emma Barroso, Carlos Beas-Zarate, Carme Auladell, Mercè Pallàs, Manuel Vázquez-Carrera, Gemma Casadesús, Jaume Folch, Antoni Camin. Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease. Biochimica et biophysica acta. vol 1842. issue 9. 2014-09-25. PMID:24887203. early alterations in energy metabolism in the hippocampus of appswe/ps1de9 mouse model of alzheimer's disease. 2014-09-25 2023-08-13 mouse
Ignacio Pedrós, Dmitry Petrov, Michael Allgaier, Francesc Sureda, Emma Barroso, Carlos Beas-Zarate, Carme Auladell, Mercè Pallàs, Manuel Vázquez-Carrera, Gemma Casadesús, Jaume Folch, Antoni Camin. Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease. Biochimica et biophysica acta. vol 1842. issue 9. 2014-09-25. PMID:24887203. the present study had focused on the behavioral phenotype and gene expression profile of molecules related to insulin receptor signaling in the hippocampus of 3 and 6 month-old appswe/ps1de9 (app/ps1) transgenic mouse model of alzheimer's disease (ad). 2014-09-25 2023-08-13 mouse
Daniela Bianchi, Pasquale De Michele, Cristina Marchetti, Brunello Tirozzi, Salvatore Cuomo, Hélène Marie, Michele Miglior. Effects of increasing CREB-dependent transcription on the storage and recall processes in a hippocampal CA1 microcircuit. Hippocampus. vol 24. issue 2. 2014-09-23. PMID:24123649. the involvement of the hippocampus in learning processes and major brain diseases makes it an ideal candidate to investigate possible ways to devise effective therapies for memory-related pathologies like alzheimer's disease (ad). 2014-09-23 2023-08-12 Not clear
Katsuyoshi Mizukami, Eric E Abrahamson, Zhiping Mi, Masanori Ishikawa, Kazushi Watanabe, Setsuo Kinoshita, Takashi Asada, Milos D Ikonomovi. Immunohistochemical analysis of ubiquilin-1 in the human hippocampus: association with neurofibrillary tangle pathology. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 34. issue 1. 2014-09-19. PMID:23869942. this post mortem immunohistochemical study examined the localization and distribution of ubiquilin-1 (ubl), a shuttle protein which interacts with ubiquitin and the proteasome, in the hippocampus from alzheimer's disease (ad) dementia cases, and age-matched cases without dementia. 2014-09-19 2023-08-12 human