| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ignacio Sarasua, Sebastian Pölsterl, Christian Wachinge. Hippocampal representations for deep learning on Alzheimer's disease. Scientific reports. vol 12. issue 1. 2022-05-21. PMID:35597814. |
deep learning offers a powerful approach for analyzing hippocampal changes in alzheimer's disease (ad) without relying on handcrafted features. |
2022-05-21 |
2023-08-13 |
Not clear |
| Ignacio Sarasua, Sebastian Pölsterl, Christian Wachinge. Hippocampal representations for deep learning on Alzheimer's disease. Scientific reports. vol 12. issue 1. 2022-05-21. PMID:35597814. |
our results show that choosing an appropriate representation of the hippocampus for predicting alzheimer's disease with deep learning is crucial, since it impacts performance and ease of interpretation. |
2022-05-21 |
2023-08-13 |
Not clear |
| Xiaopeng Chen, Guoqiang Ren, Yan Li, Wa Chao, Siyuan Chen, Xuezhong Li, Shouru Xu. Level of LncRNA GAS5 and Hippocampal Volume are Associated with the Progression of Alzheimer's Disease. Clinical interventions in aging. vol 17. 2022-05-20. PMID:35592641. |
level of lncrna gas5 and hippocampal volume are associated with the progression of alzheimer's disease. |
2022-05-20 |
2023-08-13 |
Not clear |
| Xiaopeng Chen, Guoqiang Ren, Yan Li, Wa Chao, Siyuan Chen, Xuezhong Li, Shouru Xu. Level of LncRNA GAS5 and Hippocampal Volume are Associated with the Progression of Alzheimer's Disease. Clinical interventions in aging. vol 17. 2022-05-20. PMID:35592641. |
we evaluated the diagnostic value of long non-coding rna growth arrest-specific transcript 5 (gas5) and its relationship with hippocampal volume in alzheimer's disease (ad). |
2022-05-20 |
2023-08-13 |
Not clear |
| John C Morris, Michael Weiner, Chengjie Xiong, Laurel Beckett, Dean Coble, Naomi Saito, Paul S Aisen, Ricardo Allegri, Tammie L S Benzinger, Sarah B Berman, Nigel J Cairns, Maria C Carrillo, Helena C Chui, Jasmeer P Chhatwal, Carlos Cruchaga, Anne M Fagan, Martin Farlow, Nick C Fox, Bernardino Ghetti, Alison M Goate, Brian A Gordon, Neill Graff-Radford, Gregory S Day, Jason Hassenstab, Takeshi Ikeuchi, Clifford R Jack, William J Jagust, Mathias Jucker, Johannes Levin, Parinaz Massoumzadeh, Colin L Masters, Ralph Martins, Eric McDade, Hiroshi Mori, James M Noble, Ronald C Petersen, John M Ringman, Stephen Salloway, Andrew J Saykin, Peter R Schofield, Leslie M Shaw, Arthur W Toga, John Q Trojanowski, Jonathan Vöglein, Stacie Weninger, Randall J Bateman, Virginia D Buckle. Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology. Brain : a journal of neurology. 2022-05-17. PMID:35580594. |
rates of change in cognitive performance and hippocampal volume loss after symptomatic onset were more aggressive for autosomal dominant alzheimer disease participants. |
2022-05-17 |
2023-08-13 |
human |
| Shannon M Drouin, G Peggy McFall, Olivier Potvin, Pierre Bellec, Mario Masellis, Simon Duchesne, Roger A Dixo. Data-Driven Analyses of Longitudinal Hippocampal Imaging Trajectories: Discrimination and Biomarker Prediction of Change Classes. Journal of Alzheimer's disease : JAD. 2022-05-16. PMID:35570482. |
hippocampal atrophy is a well-known biomarker of neurodegeneration, such as that observed in alzheimer's disease (ad). |
2022-05-16 |
2023-08-13 |
Not clear |
| Qun Shang, Qi Zhang, Xiao Liu, Lingchen Zh. Prediction of Early Alzheimer Disease by Hippocampal Volume Changes under Machine Learning Algorithm. Computational and mathematical methods in medicine. vol 2022. 2022-05-16. PMID:35572832. |
prediction of early alzheimer disease by hippocampal volume changes under machine learning algorithm. |
2022-05-16 |
2023-08-13 |
Not clear |
| Qun Shang, Qi Zhang, Xiao Liu, Lingchen Zh. Prediction of Early Alzheimer Disease by Hippocampal Volume Changes under Machine Learning Algorithm. Computational and mathematical methods in medicine. vol 2022. 2022-05-16. PMID:35572832. |
this research was aimed at discussing the application value of different machine learning algorithms in the prediction of early alzheimer's disease (ad), which was based on hippocampal volume changes in magnetic resonance imaging (mri). |
2022-05-16 |
2023-08-13 |
Not clear |
| Shih-Hsiu J Wang, Yuanyuan Guo, John F Ervin, Jay B Lusk, Sheng Lu. Neuropathological associations of limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) differ between the oldest-old and younger-old. Acta neuropathologica. 2022-05-13. PMID:35551470. |
participants of the oldest-old with late-nc were more likely to have hippocampal sclerosis (hs) (55.9% vs. 10.5%, p < 0.001) and moderate to severe arteriolosclerosis (82.4% vs. 50%, p = 0.007), but not intermediate to high alzheimer's disease neuropathologic change (adnc) (70.6% vs. 59.2%, p = 0.486) or lewy body disease (lbd) (20.6% vs. 26.3%, p = 0.793). |
2022-05-13 |
2023-08-13 |
human |
| Marcia Ratner, Scott Downing, Ouyang Guo, Kathryn A Odamah, Tara Stewart, Vidhya Kumaresan, Weiming Xia, David Far. Role of Pharmacological Modulation of Tonic Inhibition in Hippocampal Sharp Wave Ripples Amplitude and Place Cell Firing Dynamics. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35552906. |
hippocampal hyperactivity is a hallmark of memory dysfunction associated with age related mild cognitive impairment (amci) and alzheimer's disease, leading to the hypothesis that hippocampal trisynaptic circuit hyperactivity impairs memory function. |
2022-05-13 |
2023-08-13 |
rat |
| Shanshan Wang, Taiga Ichinomiya, Brian Hea. AAV9-synapsin-caveolin-1 (AAV9-SynCav1) gene delivery preserves motor neuron and neuromuscular junction morphology, motor function and body weight, and extends survival in hSOD1 FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35557138. |
we have previously shown that synapsin-promoted cav-1 (syncav1) augments neuroplasticity, preserves synaptic ultrastructure and hippocampal learning and memory in a mouse model of alzheimer's disease. |
2022-05-13 |
2023-08-13 |
mouse |
| Fahadul Islam, Mohamed H Nafady, Md Rezaul Islam, Susmita Saha, Salma Rashid, Aklima Akter, Md Harun- Or-Rashid, Muhammad Furqan Akhtar, Asma Perveen, Ghulam Md Ashraf, Md Habibur Rahman, Sherouk Hussein Sweila. Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside. Molecular neurobiology. 2022-05-11. PMID:35545730. |
resveratrol has been demonstrated in multiple studies to have a neuroprotective, anti-inflammatory, and antioxidant characteristic and the ability to minimize aβ peptides aggregation and toxicity in the hippocampus of alzheimer's patients, stimulating neurogenesis and inhibiting hippocampal degeneration. |
2022-05-11 |
2023-08-13 |
Not clear |
| Pravat K Mandal, Divya Dwivedi, Deepika Shukla, Avantika Samkaria, Rimil Guha Roy, Yashika Arora, Komal Jinda. Interplay Between Hippocampal Glutathione Depletion and pH Increment in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-05-09. PMID:35527551. |
interplay between hippocampal glutathione depletion and ph increment in alzheimer's disease. |
2022-05-09 |
2023-08-13 |
Not clear |
| Zarui A Melikyan, María M Corrada, Anne-Marie Leiby, Seyed Ahmad Sajjadi, Syed Bukhari, Thomas J Montine, Claudia H Kawa. Cognitive resilience to three dementia-related neuropathologies in an oldest-old man: A case report from The 90+ Study. Neurobiology of aging. vol 116. 2022-05-08. PMID:35526514. |
neuropathological examination revealed intermediate level of alzheimer's disease neuropathologic change (thal phase 5, braak nft stage iv, cerad score 3), lewy bodies and neurites in the olfactory bulb, brainstem and limbic areas (braak pd stage 4), tdp-43 inclusions in the amygdala and hippocampus (late stage 2), and a microvascular lesion in putamen. |
2022-05-08 |
2023-08-13 |
human |
| Xuemei Liang, Rong Zhan. Effects of Minocycline on Cognitive Impairment, Hippocampal Inflammatory Response, and Hippocampal Alzheimer's Related Proteins in Aged Rats after Propofol Anesthesia. Disease markers. vol 2022. 2022-05-06. PMID:35521638. |
effects of minocycline on cognitive impairment, hippocampal inflammatory response, and hippocampal alzheimer's related proteins in aged rats after propofol anesthesia. |
2022-05-06 |
2023-08-13 |
rat |
| Matias Mugnaini, Diana Polania, Yannina Diaz, Marcelo Ezquer, Fernando Ezquer, Robert M J Deacon, Patricia Cogram, Emilio Kropf. Spatial maps and oscillations in the healthy hippocampus of Octodon degus, a natural model of sporadic Alzheimer's disease. Scientific reports. vol 12. issue 1. 2022-05-05. PMID:35513473. |
spatial maps and oscillations in the healthy hippocampus of octodon degus, a natural model of sporadic alzheimer's disease. |
2022-05-05 |
2023-08-13 |
mouse |
| Ho Young Park, Chong Hyun Suh, Hwon Heo, Woo Hyun Shim, Sang Joon Ki. Diagnostic performance of hippocampal volumetry in Alzheimer's disease or mild cognitive impairment: a meta-analysis. European radiology. 2022-05-04. PMID:35507052. |
diagnostic performance of hippocampal volumetry in alzheimer's disease or mild cognitive impairment: a meta-analysis. |
2022-05-04 |
2023-08-13 |
Not clear |
| Ho Young Park, Chong Hyun Suh, Hwon Heo, Woo Hyun Shim, Sang Joon Ki. Diagnostic performance of hippocampal volumetry in Alzheimer's disease or mild cognitive impairment: a meta-analysis. European radiology. 2022-05-04. PMID:35507052. |
to evaluate the diagnostic performance of hippocampal volumetry for alzheimer's disease (ad) or mild cognitive impairment (mci). |
2022-05-04 |
2023-08-13 |
Not clear |
| Thomas A Kim, Michelle D Syty, Kaitlyn Wu, Shaoyu G. Adult hippocampal neurogenesis and its impairment in Alzheimer's disease. Zoological research. vol 43. issue 3. 2022-05-03. PMID:35503338. |
adult hippocampal neurogenesis and its impairment in alzheimer's disease. |
2022-05-03 |
2023-08-13 |
Not clear |
| Trieu-Duc Vu, Naoki Ito, Kenshiro Oshima, Akiko Maruko, Akinori Nishi, Kazushige Mizoguchi, Hiroshi Odaguchi, Yoshinori Kobayashi, Norihiro Okad. Intron retention is a stress response in sensor genes and is restored by Japanese herbal medicines: A basis for future clinical applications. Gene. 2022-05-03. PMID:35504437. |
by analyzing rna-sequencing data generated from the hippocampus of the 19-week-old samp8 mouse, a model for studying age-related depression and alzheimer's disease, we showed that genes with increased ir are generally involved in multiple metabolic pathways and have pivotal roles in sensing homeostasis. |
2022-05-03 |
2023-08-13 |
mouse |