| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Koshi Ota, Tomonobu Nishii, Kensuke Fujii, Yasuo Oishi, Naoya Onishi, Kanna Ota, Hiroki Yokoyama, Akira Takas. Altered consciousness with transient abnormal signals in the hippocampus: A case report. SAGE open medical case reports. vol 9. 2021-10-30. PMID:34707870. |
many different diseases can mimic hippocampal infarction including transient global amnesia, alzheimer's disease, epilepsy, encephalitis, and encephalopathies. |
2021-10-30 |
2023-08-13 |
Not clear |
| Donatas Sederevičius, Didac Vidal-Piñeiro, Øystein Sørensen, Koen van Leemput, Juan Eugenio Iglesias, Adrian V Dalca, Douglas N Greve, Bruce Fischl, Atle Bjørnerud, Kristine B Walhovd, Anders M Fjel. Reliability and sensitivity of two whole-brain segmentation approaches included in FreeSurfer - ASEG and SAMSEG. NeuroImage. vol 237. 2021-10-29. PMID:33940143. |
we compare annual rate of hippocampal atrophy in cognitively normal older adults (n = 20), patients with mild cognitive impairment (n = 20) and alzheimer's disease (n = 20). |
2021-10-29 |
2023-08-13 |
human |
| D G Coughlin, R Ittyerah, C Peterson, J S Phillips, S Miller, K Rascovsky, D Weintraub, A D Siderowf, J E Duda, H I Hurtig, D A Wolk, C T McMillan, P A Yushkevich, M Grossman, E B Lee, J Q Trojanowski, D J Irwi. Hippocampal subfield pathologic burden in Lewy body diseases vs. Alzheimer's disease. Neuropathology and applied neurobiology. vol 46. issue 7. 2021-10-28. PMID:32892355. |
hippocampal subfield pathologic burden in lewy body diseases vs. alzheimer's disease. |
2021-10-28 |
2023-08-13 |
human |
| D G Coughlin, R Ittyerah, C Peterson, J S Phillips, S Miller, K Rascovsky, D Weintraub, A D Siderowf, J E Duda, H I Hurtig, D A Wolk, C T McMillan, P A Yushkevich, M Grossman, E B Lee, J Q Trojanowski, D J Irwi. Hippocampal subfield pathologic burden in Lewy body diseases vs. Alzheimer's disease. Neuropathology and applied neurobiology. vol 46. issue 7. 2021-10-28. PMID:32892355. |
lewy body diseases (lbd) are characterized by alpha-synuclein (syn) pathology, but comorbid alzheimer's disease (ad) pathology is common and the relationship between these pathologies in microanatomic hippocampal subfields is understudied. |
2021-10-28 |
2023-08-13 |
human |
| Evgenii Gerasimov, Alexander Erofeev, Anastasia Borodinova, Anastasia Bolshakova, Pavel Balaban, Ilya Bezprozvanny, Olga L Vlasov. Optogenetic Activation of Astrocytes-Effects on Neuronal Network Function. International journal of molecular sciences. vol 22. issue 17. 2021-10-28. PMID:34502519. |
based on these results, we concluded that opto-a1ar expressed in hippocampal astrocytes provides an opportunity to modulate the long-term synaptic plasticity optogenetically, and may potentially be used to normalize the synaptic transmission and plasticity defects in a variety of neuropathological conditions, including models of alzheimer's disease and other neurodegenerative disorders. |
2021-10-28 |
2023-08-13 |
Not clear |
| Jaedong Lee, Jeehyun Kwa. Activation of PLCβ1 enhances endocannabinoid mobilization to restore hippocampal spike-timing-dependent potentiation and contextual fear memory impaired by Alzheimer's amyloidosis. Alzheimer's research & therapy. vol 13. issue 1. 2021-10-28. PMID:34625112. |
activation of plcβ1 enhances endocannabinoid mobilization to restore hippocampal spike-timing-dependent potentiation and contextual fear memory impaired by alzheimer's amyloidosis. |
2021-10-28 |
2023-08-13 |
Not clear |
| Jaedong Lee, Jeehyun Kwa. Activation of PLCβ1 enhances endocannabinoid mobilization to restore hippocampal spike-timing-dependent potentiation and contextual fear memory impaired by Alzheimer's amyloidosis. Alzheimer's research & therapy. vol 13. issue 1. 2021-10-28. PMID:34625112. |
accumulation of amyloid beta oligomers (aβo) in alzheimer's disease (ad) impairs hippocampal long-term potentiation (ltp), leading to memory deficits. |
2021-10-28 |
2023-08-13 |
Not clear |
| Yongyan Xie, Bo Yan, Min Hou, Maofu Zhou, Chao Liu, Mengsheng Sun, Kun He, Cong Fang, Yaohui Chen, Liping Huan. Erzhi pills ameliorate cognitive dysfunction and alter proteomic hippocampus profiles induced by d-galactose and Aβ Pharmaceutical biology. vol 59. issue 1. 2021-10-28. PMID:34672897. |
erzhi pills ameliorate cognitive dysfunction and alter proteomic hippocampus profiles induced by d-galactose and aβ erzhi pills are a classic chinese medicine prescription, but their effects on alzheimer's disease (ad) are not clear. |
2021-10-28 |
2023-08-13 |
Not clear |
| Altin Kocinaj, Tabassum Chaudhury, Mohammed S Uddin, Rashad R Junaid, David B Ramsden, Geshanthi Hondhamuni, Fábio Klamt, Linda Parsons, Richard B Parson. High Expression of Nicotinamide N-Methyltransferase in Patients with Sporadic Alzheimer's Disease. Molecular neurobiology. vol 58. issue 4. 2021-10-27. PMID:33387303. |
in this study, we have compared the expression of nnmt in post-mortem medial temporal lobe, hippocampus and cerebellum of 10 alzheimer's disease (ad) and 9 non-disease control subjects using a combination of quantitative western blotting, immunohistochemistry and dual-label confocal microscopy coupled with quantitative analysis of colocalisation. |
2021-10-27 |
2023-08-13 |
human |
| Meral A Tubi, Deydeep Kothapalli, Matthew Hapenney, Franklin W Feingold, Wendy J Mack, Kevin S King, Paul M Thompson, Meredith N Braski. Regional relationships between CSF VEGF levels and Alzheimer's disease brain biomarkers and cognition. Neurobiology of aging. vol 105. 2021-10-27. PMID:34126466. |
alzheimer's disease (ad) -neuropathological hallmarks interfere with vegf signaling and modify previously detected positive associations between cerebral spinal fluid (csf) vegf and cognition and hippocampal volume. |
2021-10-27 |
2023-08-13 |
human |
| Sophie J F van der Spek, Miguel A Gonzalez-Lozano, Frank Koopmans, Suzanne S M Miedema, Iryna Paliukhovich, August B Smit, Ka Wan L. Age-Dependent Hippocampal Proteomics in the APP/PS1 Alzheimer Mouse Model: A Comparative Analysis with Classical SWATH/DIA and directDIA Approaches. Cells. vol 10. issue 7. 2021-10-26. PMID:34202490. |
age-dependent hippocampal proteomics in the app/ps1 alzheimer mouse model: a comparative analysis with classical swath/dia and directdia approaches. |
2021-10-26 |
2023-08-13 |
mouse |
| Rocío Alfaro-Ruiz, Alejandro Martín-Belmonte, Carolina Aguado, Félix Hernández, Ana Esther Moreno-Martínez, Jesús Ávila, Rafael Lujá. The Expression and Localisation of G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channels Is Differentially Altered in the Hippocampus of Two Mouse Models of Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 20. 2021-10-26. PMID:34681766. |
the expression and localisation of g-protein-coupled inwardly rectifying potassium (girk) channels is differentially altered in the hippocampus of two mouse models of alzheimer's disease. |
2021-10-26 |
2023-08-13 |
mouse |
| Xiaochuan Zhang, Xianzhen Yin, Jingjing Zhang, Anan Li, Hui Gong, Qingming Luo, Haiyan Zhang, Zhaobing Gao, Hualiang Jian. High-resolution mapping of brain vasculature and its impairment in the hippocampus of Alzheimer's disease mice. National science review. vol 6. issue 6. 2021-10-26. PMID:34692000. |
high-resolution mapping of brain vasculature and its impairment in the hippocampus of alzheimer's disease mice. |
2021-10-26 |
2023-08-13 |
mouse |
| Jiangxia Ni, Yongfei Ren, Tonghui Su, Jia Zhou, Chaoying Fu, Yi Lu, De'an Li, Jing Zhao, Yunxia Li, Yaoyang Zhang, Yanshan Fang, Nan Liu, Yang Geng, Yelin Che. Loss of TDP-43 function underlies hippocampal and cortical synaptic deficits in TDP-43 proteinopathies. Molecular psychiatry. 2021-10-26. PMID:34697451. |
interestingly, m337v and a90v mutants also display dominant negative activities against wt tdp-43, partially explaining why m337v transgenic mice develop hippocampal degeneration similar to that in excitatory neuronal tdp-43 knockout mice, and why a90v mutation is associated with alzheimer's disease. |
2021-10-26 |
2023-08-13 |
mouse |
| Latha Velayudhan, Susan Francis, Richard Dury, Subhadip Paul, Sana Bestwn, Penny Gowland, Sagnik Bhattacharyy. Hippocampal functional connectivity in Alzheimer's disease: a resting state 7T fMRI study. International psychogeriatrics. vol 33. issue 1. 2021-10-25. PMID:33076998. |
hippocampal functional connectivity in alzheimer's disease: a resting state 7t fmri study. |
2021-10-25 |
2023-08-13 |
Not clear |
| Hannah M O Reid, Nathan Chen-Mack, Taylor Snowden, Brian R Christi. Understanding Changes in Hippocampal Interneurons Subtypes in the Pathogenesis of Alzheimer's Disease: A Systematic Review. Brain connectivity. vol 11. issue 3. 2021-10-25. PMID:33559520. |
understanding changes in hippocampal interneurons subtypes in the pathogenesis of alzheimer's disease: a systematic review. |
2021-10-25 |
2023-08-13 |
Not clear |
| Hannah Walgrave, Sriram Balusu, Sarah Snoeck, Elke Vanden Eynden, Katleen Craessaerts, Nicky Thrupp, Leen Wolfs, Katrien Horré, Yannick Fourne, Alicja Ronisz, Edina Silajdžić, Amber Penning, Giorgia Tosoni, Zsuzsanna Callaerts-Vegh, Rudi D'Hooge, Dietmar Rudolf Thal, Henrik Zetterberg, Sandrine Thuret, Mark Fiers, Carlo Sala Frigerio, Bart De Strooper, Evgenia Salt. Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease. Cell stem cell. vol 28. issue 10. 2021-10-25. PMID:34033742. |
restoring mir-132 expression rescues adult hippocampal neurogenesis and memory deficits in alzheimer's disease. |
2021-10-25 |
2023-08-13 |
mouse |
| Hannah Walgrave, Sriram Balusu, Sarah Snoeck, Elke Vanden Eynden, Katleen Craessaerts, Nicky Thrupp, Leen Wolfs, Katrien Horré, Yannick Fourne, Alicja Ronisz, Edina Silajdžić, Amber Penning, Giorgia Tosoni, Zsuzsanna Callaerts-Vegh, Rudi D'Hooge, Dietmar Rudolf Thal, Henrik Zetterberg, Sandrine Thuret, Mark Fiers, Carlo Sala Frigerio, Bart De Strooper, Evgenia Salt. Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease. Cell stem cell. vol 28. issue 10. 2021-10-25. PMID:34033742. |
in alzheimer's disease (ad), the process of generating new neurons at the hippocampal neurogenic niche is impeded, yet the mechanisms involved are unknown. |
2021-10-25 |
2023-08-13 |
mouse |
| Sehwan Kim, Gyeong Joon Moon, Hyung Jun Kim, Do-Geun Kim, Jaekwang Kim, Youngpyo Nam, Chanchal Sharma, Eunju Leem, Shinrye Lee, Kyu-Sung Kim, Chang Man Ha, Catriona McLean, Byung Kwan Jin, Won-Ho Shin, Dong Woon Kim, Yong-Seok Oh, Chang-Won Hong, Sang Ryong Ki. Control of hippocampal prothrombin kringle-2 (pKr-2) expression reduces neurotoxic symptoms in five familial Alzheimer's disease mice. British journal of pharmacology. 2021-10-25. PMID:34524687. |
control of hippocampal prothrombin kringle-2 (pkr-2) expression reduces neurotoxic symptoms in five familial alzheimer's disease mice. |
2021-10-25 |
2023-08-13 |
mouse |
| Sehwan Kim, Gyeong Joon Moon, Hyung Jun Kim, Do-Geun Kim, Jaekwang Kim, Youngpyo Nam, Chanchal Sharma, Eunju Leem, Shinrye Lee, Kyu-Sung Kim, Chang Man Ha, Catriona McLean, Byung Kwan Jin, Won-Ho Shin, Dong Woon Kim, Yong-Seok Oh, Chang-Won Hong, Sang Ryong Ki. Control of hippocampal prothrombin kringle-2 (pKr-2) expression reduces neurotoxic symptoms in five familial Alzheimer's disease mice. British journal of pharmacology. 2021-10-25. PMID:34524687. |
there is a scarcity of information regarding the role of prothrombin kringle-2 (pkr-2), which can be generated by active thrombin, in hippocampal neurodegeneration and alzheimer's disease (ad). |
2021-10-25 |
2023-08-13 |
mouse |