| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fang Lan, Daniel Roquet, Marshall A Dalton, Hashim El-Omar, Rebekah M Ahmed, Olivier Piguet, Muireann Iris. Exploring graded profiles of hippocampal atrophy along the anterior-posterior axis in semantic dementia and Alzheimer's disease. Neurobiology of aging. vol 135. 2024-01-17. PMID:38232501. |
exploring graded profiles of hippocampal atrophy along the anterior-posterior axis in semantic dementia and alzheimer's disease. |
2024-01-17 |
2024-01-20 |
human |
| Fang Lan, Daniel Roquet, Marshall A Dalton, Hashim El-Omar, Rebekah M Ahmed, Olivier Piguet, Muireann Iris. Exploring graded profiles of hippocampal atrophy along the anterior-posterior axis in semantic dementia and Alzheimer's disease. Neurobiology of aging. vol 135. 2024-01-17. PMID:38232501. |
volumetric differences in hippocampal subregions were compared between 21 sd, 24 matched alzheimer's disease (ad), and 27 healthy older control participants. |
2024-01-17 |
2024-01-20 |
human |
| Mehrzad Moghadasi, Fatemeh Akbari, Parisa Najaf. Interaction of aerobic exercise and crocin improves memory, learning and hypocampic tau and neurotrophins gene expression in rats treated with trimethytin as a model of Alzheimer's disease. Molecular biology reports. vol 51. issue 1. 2024-01-16. PMID:38227208. |
alzheimer's disease (ad) is characterized by progressive cognitive decline and a reduction in hippocampal neurotrophins, in which trimethytin (tmt) infusion causes tangles and neuronal dysfunction, creating an ad-like model in rats. |
2024-01-16 |
2024-01-18 |
rat |
| Elena Spoleti, Livia La Barbera, Emma Cauzzi, Maria Luisa De Paolis, Luana Saba, Ramona Marino, Giuseppe Sciamanna, Vincenzo Di Lazzaro, Flavio Keller, Annalisa Nobili, Paraskevi Krashia, Marcello D'Ameli. Dopamine neuron degeneration in the Ventral Tegmental Area causes hippocampal hyperexcitability in experimental Alzheimer's Disease. Molecular psychiatry. 2024-01-16. PMID:38228889. |
dopamine neuron degeneration in the ventral tegmental area causes hippocampal hyperexcitability in experimental alzheimer's disease. |
2024-01-16 |
2024-01-19 |
mouse |
| Tyler R Bell, Carol E Franz, Lisa T Eyler, Christine Fennema-Notestine, Olivia K Puckett, Stephen M Dorros, Matthew S Panizzon, Rahul C Pearce, Donald J Hagler, Michael J Lyons, Asad Beck, Jeremy A Elman, William S Kreme. Probable chronic pain, brain structure, and Alzheimer's plasma biomarkers in older men. The journal of pain. 2024-01-10. PMID:38199594. |
in this study, we provide one of the first assessments in humans, examining the associations of probable chronic pain with hippocampal volume, integrity of the locus coeruleus (lc)-an upstream site of tau deposition-and alzheimer's disease (ad)-related plasma biomarkers. |
2024-01-10 |
2024-01-13 |
mouse |
| Morgan C Pait, Sarah D Kaye, Yixin Su, Ashish Kumar, Sangeeta Singh, Stephen C Gironda, Samantha Vincent, Maria Anwar, Caitlin M Carroll, James Andy Snipes, Jingyun Lee, Cristina M Furdui, Gagan Deep, Shannon L Macaule. Novel method for collecting hippocampal interstitial fluid extracellular vesicles (EV Journal of extracellular vesicles. vol 13. issue 1. 2024-01-09. PMID:38191961. |
novel method for collecting hippocampal interstitial fluid extracellular vesicles (ev brain-derived extracellular vesicles (evs) play an active role in alzheimer's disease (ad), relaying important physiological information about their host tissues. |
2024-01-09 |
2024-01-10 |
mouse |
| Akihiko Taguchi, Yuka Okinaka, Akiko Takeda, Takayuki Okamoto, Johannes Boltze, Carsten Claussen, Sheraz Gu. Activation of neurogenesis in the hippocampus is a novel therapeutic target for Alzheimer's disease. Neuroprotection. vol 1. issue 2. 2024-01-08. PMID:38188232. |
activation of neurogenesis in the hippocampus is a novel therapeutic target for alzheimer's disease. |
2024-01-08 |
2024-01-10 |
Not clear |
| Maria Stefania De Simone, Gianfranco Spalletta, Daniela Vecchio, Andrea Bassi, Giovanni Augusto Carlesimo, Fabrizio Pira. The Role of the Anterior Thalamic Nuclei in the Genesis of Memory Disorders in Alzheimer's Disease: An Exploratory Study. Journal of Alzheimer's disease : JAD. vol 97. issue 1. 2024-01-08. PMID:38189755. |
increasing evidence is demonstrating that degeneration of specific thalamic nuclei, in addition to the hippocampus, may occur in alzheimer's disease (ad) from the prodromal stage (mild cognitive impairment - mci) and contribute to memory impairment. |
2024-01-08 |
2024-01-10 |
Not clear |
| Jeremy S Francis, Quy Nguyen, Vladimir Markov, Paola Leon. Over-expression of N-acetylaspartate synthase exacerbates pathological energetic deficit and accelerates cognitive decline in the 5xFAD mouse. Journal of neurochemistry. 2024-01-05. PMID:38178803. |
we show here that over-expression of the rate-limiting naa synthetic enzyme in the hippocampus of the 5x familial alzheimer's disease (5xfad) mouse results in an exaggerated pathological atp deficit and accelerated cognitive decline. |
2024-01-05 |
2024-01-07 |
mouse |
| Zicheng Ling, Sirui Zhou, Yancheng Zhou, Wanyu Zhong, Zhonghao Su, Zhenxia Qi. Protective role of madecassoside from Centella asiatica against protein L-isoaspartyl methyltransferase deficiency-induced neurodegeneration. Neuropharmacology. 2024-01-05. PMID:38181970. |
aside from abnormal accumulation of l-isoasp, pimt knockout (ko) mice mirrors some neuropathological hallmarks such as anxiety-like behaviors, impaired spatial memory and aberrant synaptic plasticity in the hippocampus of neurodegenerative diseases (nds), including alzheimer's disease (ad) and related dementias, and parkinson's disease (pd). |
2024-01-05 |
2024-01-08 |
mouse |
| Clement Poiret, Antoine Bouyeure, Sandesh Patil, Cécile Boniteau, Edouard Duchesnay, Antoine Grigis, Frederic Lemaitre, Marion Noulhian. Attention-gated 3D CapsNet for robust hippocampal segmentation. Journal of medical imaging (Bellingham, Wash.). vol 11. issue 1. 2024-01-04. PMID:38173654. |
the hippocampus is organized in subfields (hsf) involved in learning and memory processes and widely implicated in pathologies at different ages of life, from neonatal hypoxia to temporal lobe epilepsy or alzheimer's disease. |
2024-01-04 |
2024-01-06 |
Not clear |
| Ana Rita Agra Almeida Quadros, Zhaozhi Li, Xue Wang, I Sandra Ndayambaje, Sandeep Aryal, Nandini Ramesh, Matthew Nolan, Rojashree Jayakumar, Yi Han, Hannah Stillman, Corey Aguilar, Hayden J Wheeler, Theresa Connors, Jone Lopez-Erauskin, Michael W Baughn, Ze'ev Melamed, Melinda S Beccari, Laura Olmedo Martínez, Michael Canori, Chao-Zong Lee, Laura Moran, Isabelle Draper, Alan S Kopin, Derek H Oakley, Dennis W Dickson, Don W Cleveland, Bradley T Hyman, Sudeshna Das, Nilüfer Ertekin-Taner, Clotilde Lagier-Tourenn. Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease. Acta neuropathologica. vol 147. issue 1. 2024-01-04. PMID:38175301. |
in alzheimer's disease, tdp-43 pathology is predominantly observed in the limbic system and correlates with cognitive decline and reduced hippocampal volume. |
2024-01-04 |
2024-01-06 |
Not clear |
| Xiang Zhou, Kangning Dong, Shihua Zhan. Integrating spatial transcriptomics data across different conditions, technologies and developmental stages. Nature computational science. vol 3. issue 10. 2024-01-04. PMID:38177758. |
we apply staligner to st datasets of the human cortex slices from different samples, the mouse olfactory bulb slices generated by two profiling technologies, the mouse hippocampus tissue slices under normal and alzheimer's disease conditions, and the spatiotemporal atlases of mouse organogenesis. |
2024-01-04 |
2024-01-07 |
mouse |
| C Pomilio, J Presa, C Oses, A Vinuesa, M Bentivegna, A Gregosa, M Riudavets, G Sevlever, V Galvan, V Levi, J Beauquis, F Saravi. Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer's Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models. Molecular neurobiology. 2024-01-03. PMID:38172288. |
loss of direct vascular contact to astrocytes in the hippocampus as an initial event in alzheimer's disease. |
2024-01-03 |
2024-01-06 |
mouse |
| C Pomilio, J Presa, C Oses, A Vinuesa, M Bentivegna, A Gregosa, M Riudavets, G Sevlever, V Galvan, V Levi, J Beauquis, F Saravi. Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer's Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models. Molecular neurobiology. 2024-01-03. PMID:38172288. |
furthermore, our results from human and mouse brain samples provide evidence for the crucial involvement of the hippocampal vasculature in alzheimer's disease. |
2024-01-03 |
2024-01-06 |
mouse |
| Chiara Criscuolo, Elissavet Chartampila, Stephen D Ginsberg, Helen E Scharfma. Dentate gyrus granule cells show stability of BDNF protein expression in mossy fiber axons with age and resistance to Alzheimer's disease neuropathology in a mouse model. eNeuro. 2024-01-02. PMID:38164567. |
hippocampal bdnf has been implicated in alzheimer's disease (ad) because hippocampal levels in ad patients and ad animal models are often downregulated, suggesting that reduced bdnf contributes to ad. |
2024-01-02 |
2024-01-05 |
mouse |
| Yaqiong Xiao, Yubin Hu, Kaiyu Huan. Atrophy of hippocampal subfields relates to memory decline during the pathological progression of Alzheimer's disease. Frontiers in aging neuroscience. vol 15. 2023-12-27. PMID:38149170. |
atrophy of hippocampal subfields relates to memory decline during the pathological progression of alzheimer's disease. |
2023-12-27 |
2023-12-29 |
Not clear |
| Yaqiong Xiao, Yubin Hu, Kaiyu Huan. Atrophy of hippocampal subfields relates to memory decline during the pathological progression of Alzheimer's disease. Frontiers in aging neuroscience. vol 15. 2023-12-27. PMID:38149170. |
it has been well documented that atrophy of hippocampus and hippocampal subfields is closely linked to cognitive decline in normal aging and patients with mild cognitive impairment (mci) and alzheimer's disease (ad). |
2023-12-27 |
2023-12-29 |
Not clear |
| Hong-Ying Li, Yuan Shen, Lu-Shuang Xie, Qiao-Feng Wu, Shu-Guang Y. Moxibustion influences hippocampal microglia polarization via IL-33/ST2 pathway in Alzheimer's disease mice. Zhen ci yan jiu = Acupuncture research. vol 48. issue 12. 2023-12-26. PMID:38146242. |
moxibustion influences hippocampal microglia polarization via il-33/st2 pathway in alzheimer's disease mice. |
2023-12-26 |
2023-12-28 |
mouse |
| Justinas J Dainauskas, Paola Vitale, Sebastien Moreno, Hélène Marie, Michele Migliore, Ausra Saudargien. Altered synaptic plasticity at hippocampal CA1-CA3 synapses in Alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models. Frontiers in computational neuroscience. vol 17. 2023-12-22. PMID:38130706. |
altered synaptic plasticity at hippocampal ca1-ca3 synapses in alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models. |
2023-12-22 |
2023-12-24 |
Not clear |