All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
Nana Liu, Jiayuan Xu, Huaigui Liu, Shijie Zhang, Miaoxin Li, Yao Zhou, Wen Qin, Mulin Jun Li, Chunshui Y. Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer's disease. PLoS genetics. vol 17. issue 2. 2021-06-21. PMID:33630843. genome-wide association studies (gwass) have identified multiple susceptibility loci for alzheimer's disease (ad), which is characterized by early and progressive damage to the hippocampus. 2021-06-21 2023-08-13 Not clear
Katie Dyer-Reaves, Anthoni M Goodman, Amy R Nelson, Lori L McMaho. Alpha1-Adrenergic Receptor Mediated Long-Term Depression at CA3-CA1 Synapses Can Be Induced Frontiers in synaptic neuroscience. vol 11. 2021-06-18. PMID:31649525. alpha1-adrenergic receptor mediated long-term depression at ca3-ca1 synapses can be induced locus coeruleus (lc) provides the sole source of noradrenergic (na) innervation to hippocampus, and it undergoes significant degeneration early in alzheimer's disease (ad). 2021-06-18 2023-08-13 Not clear
Mehrnoosh Nikpour, Ali Sharafi, Mehrdad Hamidi, Sina Andali. Effect of Colloidal Aqueous Solution of Fullerene (C60) in the Presence of a P-Glycoprotein Inhibitor (Verapamil) on Spatial Memory and Hippocampal Expression of Sirtuin6, SELADIN1, and AQP1 Genes in a Rat Model of Alzheimer's Disease. ACS chemical neuroscience. vol 11. issue 17. 2021-06-18. PMID:32631043. effect of colloidal aqueous solution of fullerene (c60) in the presence of a p-glycoprotein inhibitor (verapamil) on spatial memory and hippocampal expression of sirtuin6, seladin1, and aqp1 genes in a rat model of alzheimer's disease. 2021-06-18 2023-08-13 rat
Tiago Mendes, Adrien Herledan, Florence Leroux, Benoit Deprez, Jean-Charles Lambert, Devrim Kilin. High-Content Screening for Protein-Protein Interaction Modulators Using Proximity Ligation Assay in Primary Neurons. Current protocols in cell biology. vol 86. issue 1. 2021-06-17. PMID:31876395. we recently developed a high-content screening model based on primary hippocampal neurons cultured in 384-well plates and screened a library of ∼1100 compounds using a pla between tau and bridging integrator 1, a genetic risk factor for alzheimer's disease. 2021-06-17 2023-08-13 rat
Xueju Zhang, Weiwei Liu, Yan Cao, Wen Ta. Hippocampus Proteomics and Brain Lipidomics Reveal Network Dysfunction and Lipid Molecular Abnormalities in APP/PS1 Mouse Model of Alzheimer's Disease. Journal of proteome research. vol 19. issue 8. 2021-06-17. PMID:32510958. hippocampus proteomics and brain lipidomics reveal network dysfunction and lipid molecular abnormalities in app/ps1 mouse model of alzheimer's disease. 2021-06-17 2023-08-13 mouse
Silvia Picciolini, Alice Gualerzi, Cristiano Carlomagno, Monia Cabinio, Stefano Sorrentino, Francesca Baglio, Marzia Bedon. An SPRi-based biosensor pilot study: Analysis of multiple circulating extracellular vesicles and hippocampal volume in Alzheimer's disease. Journal of pharmaceutical and biomedical analysis. vol 192. 2021-06-17. PMID:33038641. an spri-based biosensor pilot study: analysis of multiple circulating extracellular vesicles and hippocampal volume in alzheimer's disease. 2021-06-17 2023-08-13 human
Wen Tang, Zhaoyou Meng, Ning Li, Yiyan Liu, Li Li, Dongfeng Chen, Yang Yan. Roles of Gut Microbiota in the Regulation of Hippocampal Plasticity, Inflammation, and Hippocampus-Dependent Behaviors. Frontiers in cellular and infection microbiology. vol 10. 2021-06-17. PMID:33585279. the hippocampus is the center of learning and memory, and plays a pivotal role in neurodegenerative diseases, such as alzheimer's disease (ad). 2021-06-17 2023-08-13 mouse
Idoia Blanco-Luquin, Blanca Acha, Amaya Urdánoz-Casado, Javier Sánchez-Ruiz De Gordoa, Janire Vicuña-Urriza, Miren Roldán, Alberto Labarga, María Victoria Zelaya, Carolina Cabello, Iván Méndez-López, Maite Mendioro. Early epigenetic changes of Alzheimer's disease in the human hippocampus. Epigenetics. vol 15. issue 10. 2021-06-15. PMID:32233750. early epigenetic changes of alzheimer's disease in the human hippocampus. 2021-06-15 2023-08-13 human
Joseph M Schul. The Potential of Induced Pluripotent Stem Cells to Treat and Model Alzheimer's Disease. Stem cells international. vol 2021. 2021-06-15. PMID:34122554. an estimated 6.2 million americans aged 65 or older are currently living with alzheimer's disease (ad), a neurodegenerative disease that disrupts an individual's ability to function independently through the degeneration of key regions in the brain, including but not limited to the hippocampus, the prefrontal cortex, and the motor cortex. 2021-06-15 2023-08-13 human
Laura Serra, Marco Bozzali, Lucia Fadda, Maria Stefania De Simone, Michela Bruschini, Roberta Perri, Carlo Caltagirone, Giovanni A Carlesim. The role of hippocampus in the retrieval of autobiographical memories in patients with amnestic Mild Cognitive Impairment due to Alzheimer's disease. Journal of neuropsychology. vol 14. issue 1. 2021-06-14. PMID:30451384. the role of hippocampus in the retrieval of autobiographical memories in patients with amnestic mild cognitive impairment due to alzheimer's disease. 2021-06-14 2023-08-13 Not clear
Laura Serra, Marco Bozzali, Lucia Fadda, Maria Stefania De Simone, Michela Bruschini, Roberta Perri, Carlo Caltagirone, Giovanni A Carlesim. The role of hippocampus in the retrieval of autobiographical memories in patients with amnestic Mild Cognitive Impairment due to Alzheimer's disease. Journal of neuropsychology. vol 14. issue 1. 2021-06-14. PMID:30451384. the role of the hippocampus and neocortical areas in the retrieval of past memories in pre-dementia alzheimer's disease (ad) patients was investigated. 2021-06-14 2023-08-13 Not clear
Susana S Correia, Rajesh R Iyengar, Peter Germano, Kim Tang, Sylvie G Bernier, Chad D Schwartzkopf, Jenny Tobin, Thomas W-H Lee, Guang Liu, Sarah Jacobson, Andrew Carvalho, Glen R Rennie, Joon Jung, Paul A Renhowe, Elisabeth Lonie, Christopher J Winrow, John R Hadcock, Juli E Jones, Mark G Curri. The CNS-Penetrant Soluble Guanylate Cyclase Stimulator CY6463 Reveals its Therapeutic Potential in Neurodegenerative Diseases. Frontiers in pharmacology. vol 12. 2021-06-12. PMID:34108877. in models of neurodegeneration, cy6463 treatment increased long-term potentiation (ltp) in hippocampal slices from a huntington's disease mouse model and decreased the loss of dendritic spines in aged and alzheimer's disease mouse models. 2021-06-12 2023-08-13 mouse
Anqi Shi, Alexandra L Petrache, Jiachen Shi, Afia B Al. Preserved Calretinin Interneurons in an App Model of Alzheimer's Disease Disrupt Hippocampal Inhibition via Upregulated P2Y1 Purinoreceptors. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-09. PMID:31407772. preserved calretinin interneurons in an app model of alzheimer's disease disrupt hippocampal inhibition via upregulated p2y1 purinoreceptors. 2021-06-09 2023-08-13 mouse
Gianni Mancini, Wagner C Martins, Jade de Oliveira, Andreza Fabro de Bem, Carla I Tasc. Atorvastatin Improves Mitochondrial Function and Prevents Oxidative Stress in Hippocampus Following Amyloid-β Molecular neurobiology. vol 57. issue 10. 2021-06-09. PMID:32683653. atorvastatin improves mitochondrial function and prevents oxidative stress in hippocampus following amyloid-β amyloid-β (aβ) peptides play a significant role in the pathogenesis of alzheimer's disease (ad). 2021-06-09 2023-08-13 Not clear
K Shaw, L Bell, K Boyd, D M Grijseels, D Clarke, O Bonnar, H S Crombag, C N Hal. Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences. Nature communications. vol 12. issue 1. 2021-06-09. PMID:34045465. the hippocampus is essential for spatial and episodic memory but is damaged early in alzheimer's disease and is very sensitive to hypoxia. 2021-06-09 2023-08-13 mouse
K Shaw, L Bell, K Boyd, D M Grijseels, D Clarke, O Bonnar, H S Crombag, C N Hal. Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences. Nature communications. vol 12. issue 1. 2021-06-09. PMID:34045465. modelling oxygen diffusion indicates that these features of the hippocampal vasculature may restrict oxygen availability and could explain its sensitivity to damage during neurological conditions, including alzheimer's disease, where the brain's energy supply is decreased. 2021-06-09 2023-08-13 mouse
Yan Wang, Wei Lv, Yueyang Li, Dandan Liu, Xiuting He, Ting Li. Ampelopsin Improves Cognitive Impairment in Alzheimer's Disease and Effects of Inflammatory Cytokines and Oxidative Stress in the Hippocampus. Current Alzheimer research. vol 17. issue 1. 2021-06-07. PMID:31797758. ampelopsin improves cognitive impairment in alzheimer's disease and effects of inflammatory cytokines and oxidative stress in the hippocampus. 2021-06-07 2023-08-13 rat
Jing Ma, Yuan Gao, Wei Tang, Wei Huang, Yong Tan. Fluoxetine Protects against Dendritic Spine Loss in Middle-aged APPswe/PSEN1dE9 Double Transgenic Alzheimer's Disease Mice. Current Alzheimer research. vol 17. issue 1. 2021-06-07. PMID:32053075. studies have suggested that cognitive impairment in alzheimer's disease (ad) is associated with dendritic spine loss, especially in the hippocampus. 2021-06-07 2023-08-13 mouse
Gabrielle Pfutzenreuter, Kenny Nieradka, Márcia Regina Pincerati, Ilton Santos da Silv. Intracerebroventricular streptozotocin induces behavioral impairments and increases short‑term C3 gene expression in the hippocampus of Wistar rats. Acta neurobiologiae experimentalis. vol 80. issue 2. 2021-06-07. PMID:32602856. the behavioral tests were followed by brain removal and hippocampal dissection for rna extraction and qrt‑pcr to assess the expression levels of 4 alzheimer's disease related genes: mapt, apoe, c3 and ps‑1. 2021-06-07 2023-08-13 rat
Yuanyuan Shen, Lingchen Hua, Chih-Kuang Yeh, Liming Shen, Ming Ying, Zaijun Zhang, Gongping Liu, Shupeng Li, Siping Chen, Xin Chen, Xifei Yan. Ultrasound with microbubbles improves memory, ameliorates pathology and modulates hippocampal proteomic changes in a triple transgenic mouse model of Alzheimer's disease. Theranostics. vol 10. issue 25. 2021-06-07. PMID:33052247. ultrasound with microbubbles improves memory, ameliorates pathology and modulates hippocampal proteomic changes in a triple transgenic mouse model of alzheimer's disease. 2021-06-07 2023-08-13 mouse