All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
Natalia V Gulyaev. Hippocampal hyperglutamatergic signaling matters: Early targeting glutamate neurotransmission as a preventive strategy in Alzheimer's disease: An Editorial Highlight for "Riluzole attenuates glutamatergic tone and cognitive decline in AβPP/PS1 mice" on page 513. Journal of neurochemistry. vol 156. issue 4. 2021-04-28. PMID:33276416. hippocampal hyperglutamatergic signaling matters: early targeting glutamate neurotransmission as a preventive strategy in alzheimer's disease: an editorial highlight for "riluzole attenuates glutamatergic tone and cognitive decline in aβpp/ps1 mice" on page 513. 2021-04-28 2023-08-13 mouse
Jie Zheng, Hong-Lian Li, Na Tian, Fei Liu, Lu Wang, Yaling Yin, Lupeng Yue, Longyu Ma, You Wan, Jian-Zhi Wan. Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission. Cell stem cell. vol 26. issue 3. 2021-04-27. PMID:31978364. phospho-tau accumulation and adult hippocampal neurogenesis (ahn) impairment both contribute importantly to the cognitive decline in alzheimer's disease (ad), but whether and how tau dysregulates ahn in ad remain poorly understood. 2021-04-27 2023-08-13 mouse
Richard D Semb. Perspective: The Potential Role of Circulating Lysophosphatidylcholine in Neuroprotection against Alzheimer Disease. Advances in nutrition (Bethesda, Md.). vol 11. issue 4. 2021-04-27. PMID:32190891. alzheimer disease (ad), the most common cause of dementia, is a progressive disorder involving cognitive impairment, loss of learning and memory, and neurodegeneration affecting wide areas of the cerebral cortex and hippocampus. 2021-04-27 2023-08-13 Not clear
Mostafa Sabouri, Mohammadreza Kordi, Fatemeh Shabkhiz, Pejman Taghibeikzadehbadr, Zeinab Sadat Geramia. Moderate treadmill exercise improves spatial learning and memory deficits possibly via changing PDE-5, IL-1 β and pCREB expression. Experimental gerontology. vol 139. 2021-04-27. PMID:32791334. therefore, in this study, we examined the effect of aerobic training before and after induction of alzheimer's on spatial learning and memory, expression of interleukin-1 beta (il-1β), camp-responsive element-binding protein (pcreb), and phosphodiesterase-5 (pde-5) in the hippocampus of male rats wistar. 2021-04-27 2023-08-13 rat
Subin Lee, Hyunna Lee, Ki Woong Ki. Magnetic resonance imaging texture predicts progression to dementia due to Alzheimer disease earlier than hippocampal volume Journal of psychiatry & neuroscience : JPN. vol 45. issue 1. 2021-04-26. PMID:31228173. magnetic resonance imaging texture predicts progression to dementia due to alzheimer disease earlier than hippocampal volume early identification of people at risk of imminent progression to dementia due to alzheimer disease is crucial for timely intervention and treatment. 2021-04-26 2023-08-13 Not clear
Jessica E Owen, Bryndis Benediktsdottir, Elizabeth Cook, Isleifur Olafsson, Thorarinn Gislason, Stephen R Robinso. Alzheimer's disease neuropathology in the hippocampus and brainstem of people with obstructive sleep apnea. Sleep. vol 44. issue 3. 2021-04-26. PMID:32954401. alzheimer's disease neuropathology in the hippocampus and brainstem of people with obstructive sleep apnea. 2021-04-26 2023-08-13 Not clear
Jessica E Owen, Bryndis Benediktsdottir, Elizabeth Cook, Isleifur Olafsson, Thorarinn Gislason, Stephen R Robinso. Alzheimer's disease neuropathology in the hippocampus and brainstem of people with obstructive sleep apnea. Sleep. vol 44. issue 3. 2021-04-26. PMID:32954401. people with osa can experience memory deficits and have reduced hippocampal volume; these features are also characteristic of alzheimer's disease (ad), where they are accompanied by neurofibrillary tangles (nfts) and amyloid beta (aβ) plaques in the hippocampus and brainstem. 2021-04-26 2023-08-13 Not clear
Katharina Klink, Urs Jaun, Andrea Federspiel, Marina Wunderlin, Charlotte E Teunissen, Claus Kiefer, Roland Wiest, Frank Scharnowski, Ronald Sladky, Amelie Haugg, Lydia Hellrung, Jessica Pete. Targeting hippocampal hyperactivity with real-time fMRI neurofeedback: protocol of a single-blind randomized controlled trial in mild cognitive impairment. BMC psychiatry. vol 21. issue 1. 2021-04-26. PMID:33563242. several fmri studies found hyperactivity in the hippocampus during pattern separation tasks in patients with mild cognitive impairment (mci; a prodromal stage of alzheimer's disease). 2021-04-26 2023-08-13 Not clear
Jessica Izzo, Ole A Andreassen, Lars T Westlye, Dennis van der Mee. The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease. Brain research. vol 1728. 2021-04-23. PMID:31816319. the association between hippocampal subfield volumes in mild cognitive impairment and conversion to alzheimer's disease. 2021-04-23 2023-08-13 human
Jessica Izzo, Ole A Andreassen, Lars T Westlye, Dennis van der Mee. The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease. Brain research. vol 1728. 2021-04-23. PMID:31816319. the hippocampal complex, strongly implicated in alzheimer's disease (ad), is a region with functionally and structurally distinct subfields. 2021-04-23 2023-08-13 human
Jingfu Zhao, Mengzhen Wang, Wei Liu, Zegang Ma, Jie W. Activation of cannabinoid receptor 2 protects rat hippocampal neurons against Aβ-induced neuronal toxicity. Neuroscience letters. vol 735. 2021-04-23. PMID:32592731. alzheimer's disease (ad) is a dementing, neurodegenerative disorder characterized by increased accumulation of beta-amyloid peptides (aβ), degeneration of hippocampal neurons and the gradual development of learning and memory deficits. 2021-04-23 2023-08-13 rat
E J Fernández-Pérez, S Gallegos, L Armijo-Weingart, A Araya, N O Riffo-Lepe, F Cayuman, L G Aguay. Changes in neuronal excitability and synaptic transmission in nucleus accumbens in a transgenic Alzheimer's disease mouse model. Scientific reports. vol 10. issue 1. 2021-04-22. PMID:33177601. several previous studies showed that hippocampus and cortex are affected in alzheimer's disease (ad). 2021-04-22 2023-08-13 mouse
Daphne M P Naessens, Johannes G G Dobbe, Judith de Vos, Ed VanBavel, Erik N T P Bakke. Mapping Solute Clearance From the Mouse Hippocampus Using a 3D Imaging Cryomicrotome. Frontiers in neuroscience. vol 15. 2021-04-21. PMID:33867918. the hippocampus is susceptible to protein aggregation in neurodegenerative diseases such as alzheimer's disease. 2021-04-21 2023-08-13 mouse
Samaneh Zarei, Mohammad Shafiei, Maryam Firouzi, Loghman Firoozpour, Kouros Divsalar, Ali Asadipour, Tahmineh Akbarzadeh, Alireza Foroumad. Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4 Heliyon. vol 7. issue 4. 2021-04-21. PMID:33869871. design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4 alzheimer's disease (ad), is among the most growing neurodegenerative diseases, which is mainly caused by the acetylcholine neurotransmitter loss in the hippocampus and cortex. 2021-04-21 2023-08-13 Not clear
Zhi Ruan, Dhruba Pathak, Srinidhi Venkatesan Kalavai, Asuka Yoshii-Kitahara, Satoshi Muraoka, Nemil Bhatt, Kayo Takamatsu-Yukawa, Jianqiao Hu, Yuzhi Wang, Samuel Hersh, Maria Ericsson, Santhi Gorantla, Howard E Gendelman, Rakez Kayed, Seiko Ikezu, Jennifer I Luebke, Tsuneya Ikez. Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons. Brain : a journal of neurology. vol 144. issue 1. 2021-04-20. PMID:33246331. strikingly, the inoculation of alzheimer's disease or prodromal alzheimer's disease extracellular vesicles containing only 300 pg of tau into the outer molecular layer of the dentate gyrus of 18-month-old c57bl/6 mice resulted in the accumulation of abnormally phosphorylated tau throughout the hippocampus by 4.5 months, whereas inoculation of an equal amount of tau from control extracellular vesicles, isolated tau oligomers, or fibrils from the same alzheimer's disease donor showed little tau pathology. 2021-04-20 2023-08-13 mouse
Zhi Ruan, Dhruba Pathak, Srinidhi Venkatesan Kalavai, Asuka Yoshii-Kitahara, Satoshi Muraoka, Nemil Bhatt, Kayo Takamatsu-Yukawa, Jianqiao Hu, Yuzhi Wang, Samuel Hersh, Maria Ericsson, Santhi Gorantla, Howard E Gendelman, Rakez Kayed, Seiko Ikezu, Jennifer I Luebke, Tsuneya Ikez. Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons. Brain : a journal of neurology. vol 144. issue 1. 2021-04-20. PMID:33246331. furthermore, alzheimer's disease extracellular vesicles induced misfolding of endogenous tau in both oligomeric and sarkosyl-insoluble forms in the hippocampal region. 2021-04-20 2023-08-13 mouse
James W Daily, Suna Kang, Sunmin Par. Protection against Alzheimer's disease by luteolin: Role of brain glucose regulation, anti-inflammatory activity, and the gut microbiota-liver-brain axis. BioFactors (Oxford, England). vol 47. issue 2. 2021-04-20. PMID:33347668. alzheimer's disease (ad) is induced by the deposition of amyloid-beta (aβ) in the hippocampus and the formation of neurotoxic aβ plaques. 2021-04-20 2023-08-13 human
Shasha Song, Jingjiong Chen, Pinpin Xiao, Hao Duan, Yajun Zhou, Feng Wang, Hongmei Wang, Yuwu Zhao, Zhi Gen. Role of Macrophages in Status Epilepticus Predisposing to Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 73. issue 1. 2021-04-19. PMID:31796682. continuous epileptic seizures hallmark status epilepticus, leading to preferential neuronal cell loss in the hippocampus that can progress into alzheimer's disease. 2021-04-19 2023-08-13 rat
Jin-Ting He, Xin Zhao, Lei Xu, Cui-Ying Ma. Vascular Risk Factors and Alzheimer's Disease: Blood-Brain Barrier Disruption, Metabolic Syndromes, and Molecular Links. Journal of Alzheimer's disease : JAD. vol 73. issue 1. 2021-04-19. PMID:31815697. alzheimer's disease (ad) is a neurodegenerative disorder, marked by cortical and hippocampal deposition of amyloid-β (aβ) plaques and neurofibrillary tangles and cognitive impairment. 2021-04-19 2023-08-13 Not clear
Natalie Tomaszewski, Xulei He, Victoria Solomon, Mitchell Lee, Wendy J Mack, Joseph F Quinn, Meredith N Braskie, Hussein N Yassin. Effect of APOE Genotype on Plasma Docosahexaenoic Acid (DHA), Eicosapentaenoic Acid, Arachidonic Acid, and Hippocampal Volume in the Alzheimer's Disease Cooperative Study-Sponsored DHA Clinical Trial. Journal of Alzheimer's disease : JAD. vol 74. issue 3. 2021-04-19. PMID:32116250. effect of apoe genotype on plasma docosahexaenoic acid (dha), eicosapentaenoic acid, arachidonic acid, and hippocampal volume in the alzheimer's disease cooperative study-sponsored dha clinical trial. 2021-04-19 2023-08-13 Not clear