| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marina Buciuc, Alexandra M Wennberg, Stephen D Weigand, Melissa E Murray, Matthew L Senjem, Anthony J Spychalla, Bradley F Boeve, David S Knopman, Clifford R Jack, Kejal Kantarci, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Jennifer L Whitwell, Keith A Joseph. Effect Modifiers of TDP-43-Associated Hippocampal Atrophy Rates in Patients with Alzheimer's Disease Neuropathological Changes. Journal of Alzheimer's disease : JAD. vol 73. issue 4. 2021-05-06. PMID:31929165. |
transactive response dna-binding protein of 43 kda (tdp-43) is associated with hippocampal atrophy in alzheimer's disease (ad), but whether the association is modified by other factors is unknown. |
2021-05-06 |
2023-08-13 |
Not clear |
| Dickson Wong, Samir Atiya, Jennifer Fogarty, Manuel Montero-Odasso, Stephen H Pasternak, Chris Brymer, Michael J Borrie, Robert Barth. Reduced Hippocampal Glutamate and Posterior Cingulate N-Acetyl Aspartate in Mild Cognitive Impairment and Alzheimer's Disease Is Associated with Episodic Memory Performance and White Matter Integrity in the Cingulum: A Pilot Study. Journal of Alzheimer's disease : JAD. vol 73. issue 4. 2021-05-06. PMID:31958093. |
reduced hippocampal glutamate and posterior cingulate n-acetyl aspartate in mild cognitive impairment and alzheimer's disease is associated with episodic memory performance and white matter integrity in the cingulum: a pilot study. |
2021-05-06 |
2023-08-13 |
Not clear |
| Yiying Wang, Huajun Sheng, Jing Zhao, Ling Guo, Jianing Liu, Jin Xu, Qian Liu, Juan Huang, Rong Jiang, Shengwei Gan, Guoping Qiu, Weitian Lu, Shiye Xu, Shujuan Zh. Changes in the prefrontal cortex after the hippocampus was injected with Aβ Neuroscience letters. vol 741. 2021-05-04. PMID:33186609. |
changes in the prefrontal cortex after the hippocampus was injected with aβ alzheimer's disease (ad) is one of the common neurodegenerative illnesses in aging populations around the world. |
2021-05-04 |
2023-08-13 |
Not clear |
| Bo Lei, Jiaxin Liu, Zhihui Yao, Yan Xiao, Xiaoling Zhang, Yueting Zhang, Jianguo X. NF-κB-Induced Upregulation of miR-146a-5p Promoted Hippocampal Neuronal Oxidative Stress and Pyroptosis Frontiers in cellular neuroscience. vol 15. 2021-05-04. PMID:33935653. |
nf-κb-induced upregulation of mir-146a-5p promoted hippocampal neuronal oxidative stress and pyroptosis alzheimer's disease (ad) is a common neurodegenerative disorder that places a heavy burden on patients and society. |
2021-05-04 |
2023-08-13 |
Not clear |
| Pan Wang, Hai-Juan Sui, Xiao-Jia Li, Li-Na Bai, Jing Bi, Hong La. Melatonin ameliorates microvessel abnormalities in the cerebral cortex and hippocampus in a rat model of Alzheimer's disease. Neural regeneration research. vol 16. issue 4. 2021-04-29. PMID:33063739. |
melatonin ameliorates microvessel abnormalities in the cerebral cortex and hippocampus in a rat model of alzheimer's disease. |
2021-04-29 |
2023-08-13 |
rat |
| Pan Wang, Hai-Juan Sui, Xiao-Jia Li, Li-Na Bai, Jing Bi, Hong La. Melatonin ameliorates microvessel abnormalities in the cerebral cortex and hippocampus in a rat model of Alzheimer's disease. Neural regeneration research. vol 16. issue 4. 2021-04-29. PMID:33063739. |
these findings suggest that melatonin can improve microvessel abnormalities in the cerebral cortex and hippocampus by lowering the expression of vascular endothelial growth factor and its receptors, thereby improving the cognitive function of patients with alzheimer's disease. |
2021-04-29 |
2023-08-13 |
rat |
| Karen Ritchie, Dennis Chan, Tam Watermeye. The cognitive consequences of the COVID-19 epidemic: collateral damage? Brain communications. vol 2. issue 2. 2021-04-28. PMID:33074266. |
the hippocampus appears to be particularly vulnerable to coronavirus infections, thus increasing the probability of post-infection memory impairment, and acceleration of neurodegenerative disorders such as alzheimer's disease. |
2021-04-28 |
2023-08-13 |
Not clear |
| Natalia V Gulyaev. Hippocampal hyperglutamatergic signaling matters: Early targeting glutamate neurotransmission as a preventive strategy in Alzheimer's disease: An Editorial Highlight for "Riluzole attenuates glutamatergic tone and cognitive decline in AβPP/PS1 mice" on page 513. Journal of neurochemistry. vol 156. issue 4. 2021-04-28. PMID:33276416. |
hippocampal hyperglutamatergic signaling matters: early targeting glutamate neurotransmission as a preventive strategy in alzheimer's disease: an editorial highlight for "riluzole attenuates glutamatergic tone and cognitive decline in aβpp/ps1 mice" on page 513. |
2021-04-28 |
2023-08-13 |
mouse |
| Jie Zheng, Hong-Lian Li, Na Tian, Fei Liu, Lu Wang, Yaling Yin, Lupeng Yue, Longyu Ma, You Wan, Jian-Zhi Wan. Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission. Cell stem cell. vol 26. issue 3. 2021-04-27. PMID:31978364. |
phospho-tau accumulation and adult hippocampal neurogenesis (ahn) impairment both contribute importantly to the cognitive decline in alzheimer's disease (ad), but whether and how tau dysregulates ahn in ad remain poorly understood. |
2021-04-27 |
2023-08-13 |
mouse |
| Richard D Semb. Perspective: The Potential Role of Circulating Lysophosphatidylcholine in Neuroprotection against Alzheimer Disease. Advances in nutrition (Bethesda, Md.). vol 11. issue 4. 2021-04-27. PMID:32190891. |
alzheimer disease (ad), the most common cause of dementia, is a progressive disorder involving cognitive impairment, loss of learning and memory, and neurodegeneration affecting wide areas of the cerebral cortex and hippocampus. |
2021-04-27 |
2023-08-13 |
Not clear |
| Mostafa Sabouri, Mohammadreza Kordi, Fatemeh Shabkhiz, Pejman Taghibeikzadehbadr, Zeinab Sadat Geramia. Moderate treadmill exercise improves spatial learning and memory deficits possibly via changing PDE-5, IL-1 β and pCREB expression. Experimental gerontology. vol 139. 2021-04-27. PMID:32791334. |
therefore, in this study, we examined the effect of aerobic training before and after induction of alzheimer's on spatial learning and memory, expression of interleukin-1 beta (il-1β), camp-responsive element-binding protein (pcreb), and phosphodiesterase-5 (pde-5) in the hippocampus of male rats wistar. |
2021-04-27 |
2023-08-13 |
rat |
| Jessica E Owen, Bryndis Benediktsdottir, Elizabeth Cook, Isleifur Olafsson, Thorarinn Gislason, Stephen R Robinso. Alzheimer's disease neuropathology in the hippocampus and brainstem of people with obstructive sleep apnea. Sleep. vol 44. issue 3. 2021-04-26. PMID:32954401. |
alzheimer's disease neuropathology in the hippocampus and brainstem of people with obstructive sleep apnea. |
2021-04-26 |
2023-08-13 |
Not clear |
| Jessica E Owen, Bryndis Benediktsdottir, Elizabeth Cook, Isleifur Olafsson, Thorarinn Gislason, Stephen R Robinso. Alzheimer's disease neuropathology in the hippocampus and brainstem of people with obstructive sleep apnea. Sleep. vol 44. issue 3. 2021-04-26. PMID:32954401. |
people with osa can experience memory deficits and have reduced hippocampal volume; these features are also characteristic of alzheimer's disease (ad), where they are accompanied by neurofibrillary tangles (nfts) and amyloid beta (aβ) plaques in the hippocampus and brainstem. |
2021-04-26 |
2023-08-13 |
Not clear |
| Katharina Klink, Urs Jaun, Andrea Federspiel, Marina Wunderlin, Charlotte E Teunissen, Claus Kiefer, Roland Wiest, Frank Scharnowski, Ronald Sladky, Amelie Haugg, Lydia Hellrung, Jessica Pete. Targeting hippocampal hyperactivity with real-time fMRI neurofeedback: protocol of a single-blind randomized controlled trial in mild cognitive impairment. BMC psychiatry. vol 21. issue 1. 2021-04-26. PMID:33563242. |
several fmri studies found hyperactivity in the hippocampus during pattern separation tasks in patients with mild cognitive impairment (mci; a prodromal stage of alzheimer's disease). |
2021-04-26 |
2023-08-13 |
Not clear |
| Subin Lee, Hyunna Lee, Ki Woong Ki. Magnetic resonance imaging texture predicts progression to dementia due to Alzheimer disease earlier than hippocampal volume Journal of psychiatry & neuroscience : JPN. vol 45. issue 1. 2021-04-26. PMID:31228173. |
magnetic resonance imaging texture predicts progression to dementia due to alzheimer disease earlier than hippocampal volume early identification of people at risk of imminent progression to dementia due to alzheimer disease is crucial for timely intervention and treatment. |
2021-04-26 |
2023-08-13 |
Not clear |
| Jessica Izzo, Ole A Andreassen, Lars T Westlye, Dennis van der Mee. The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease. Brain research. vol 1728. 2021-04-23. PMID:31816319. |
the association between hippocampal subfield volumes in mild cognitive impairment and conversion to alzheimer's disease. |
2021-04-23 |
2023-08-13 |
human |
| Jessica Izzo, Ole A Andreassen, Lars T Westlye, Dennis van der Mee. The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease. Brain research. vol 1728. 2021-04-23. PMID:31816319. |
the hippocampal complex, strongly implicated in alzheimer's disease (ad), is a region with functionally and structurally distinct subfields. |
2021-04-23 |
2023-08-13 |
human |
| Jingfu Zhao, Mengzhen Wang, Wei Liu, Zegang Ma, Jie W. Activation of cannabinoid receptor 2 protects rat hippocampal neurons against Aβ-induced neuronal toxicity. Neuroscience letters. vol 735. 2021-04-23. PMID:32592731. |
alzheimer's disease (ad) is a dementing, neurodegenerative disorder characterized by increased accumulation of beta-amyloid peptides (aβ), degeneration of hippocampal neurons and the gradual development of learning and memory deficits. |
2021-04-23 |
2023-08-13 |
rat |
| E J Fernández-Pérez, S Gallegos, L Armijo-Weingart, A Araya, N O Riffo-Lepe, F Cayuman, L G Aguay. Changes in neuronal excitability and synaptic transmission in nucleus accumbens in a transgenic Alzheimer's disease mouse model. Scientific reports. vol 10. issue 1. 2021-04-22. PMID:33177601. |
several previous studies showed that hippocampus and cortex are affected in alzheimer's disease (ad). |
2021-04-22 |
2023-08-13 |
mouse |
| Daphne M P Naessens, Johannes G G Dobbe, Judith de Vos, Ed VanBavel, Erik N T P Bakke. Mapping Solute Clearance From the Mouse Hippocampus Using a 3D Imaging Cryomicrotome. Frontiers in neuroscience. vol 15. 2021-04-21. PMID:33867918. |
the hippocampus is susceptible to protein aggregation in neurodegenerative diseases such as alzheimer's disease. |
2021-04-21 |
2023-08-13 |
mouse |