| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Neus Falg\\xc3\\xa0s, Raquel S\\xc3\\xa1nchez-Valle, N\\xc3\\xbaria Bargall\\xc3\\xb3, Mircea Balasa, Guadalupe Fern\\xc3\\xa1ndez-Villullas, Beatriz Bosch, Jaume Olives, Adri\\xc3\\xa0 Tort-Merino, Anna Antonell, Cristina Mu\\xc3\\xb1oz-Garc\\xc3\\xada, Mar\\xc3\\xada Le\\xc3\\xb3n, Oriol Grau, Magdalena Castellv\\xc3\\xad, Nina Coll-Padr\\xc3\\xb3s, Lorena Rami, Alberto Redolfi, Albert Llad\\xc3\\xb. Hippocampal atrophy has limited usefulness as a diagnostic biomarker on the early onset Alzheimer\'s disease patients: A comparison between visual and quantitative assessment. NeuroImage. Clinical. vol 23. 2020-08-06. PMID:31491836.' |
hippocampal atrophy has limited usefulness as a diagnostic biomarker on the early onset alzheimer's disease patients: a comparison between visual and quantitative assessment. |
2020-08-06 |
2023-08-13 |
human |
| b' Neus Falg\\xc3\\xa0s, Raquel S\\xc3\\xa1nchez-Valle, N\\xc3\\xbaria Bargall\\xc3\\xb3, Mircea Balasa, Guadalupe Fern\\xc3\\xa1ndez-Villullas, Beatriz Bosch, Jaume Olives, Adri\\xc3\\xa0 Tort-Merino, Anna Antonell, Cristina Mu\\xc3\\xb1oz-Garc\\xc3\\xada, Mar\\xc3\\xada Le\\xc3\\xb3n, Oriol Grau, Magdalena Castellv\\xc3\\xad, Nina Coll-Padr\\xc3\\xb3s, Lorena Rami, Alberto Redolfi, Albert Llad\\xc3\\xb. Hippocampal atrophy has limited usefulness as a diagnostic biomarker on the early onset Alzheimer\'s disease patients: A comparison between visual and quantitative assessment. NeuroImage. Clinical. vol 23. 2020-08-06. PMID:31491836.' |
nia-aa diagnostic criteria include volumetric or visual rating measures of hippocampal atrophy (ha) as a diagnostic biomarker of alzheimer's disease (ad). |
2020-08-06 |
2023-08-13 |
human |
| b' Neus Falg\\xc3\\xa0s, Raquel S\\xc3\\xa1nchez-Valle, N\\xc3\\xbaria Bargall\\xc3\\xb3, Mircea Balasa, Guadalupe Fern\\xc3\\xa1ndez-Villullas, Beatriz Bosch, Jaume Olives, Adri\\xc3\\xa0 Tort-Merino, Anna Antonell, Cristina Mu\\xc3\\xb1oz-Garc\\xc3\\xada, Mar\\xc3\\xada Le\\xc3\\xb3n, Oriol Grau, Magdalena Castellv\\xc3\\xad, Nina Coll-Padr\\xc3\\xb3s, Lorena Rami, Alberto Redolfi, Albert Llad\\xc3\\xb. Hippocampal atrophy has limited usefulness as a diagnostic biomarker on the early onset Alzheimer\'s disease patients: A comparison between visual and quantitative assessment. NeuroImage. Clinical. vol 23. 2020-08-06. PMID:31491836.' |
we aimed to determine its utility as a diagnostic biomarker for early onset alzheimer's disease (eoad) by assessing medial temporal atrophy (mta) and hippocampal volume (hv) determination. |
2020-08-06 |
2023-08-13 |
human |
| Aderemi Caleb Aladeokin, Tomoko Akiyama, Ayuko Kimura, Yayoi Kimura, Aoi Takahashi-Jitsuki, Haruko Nakamura, Hiroko Makihara, Daiki Masukawa, Jun Nakabayashi, Hisashi Hirano, Fumio Nakamura, Takashi Saito, Takaomi Saido, Yoshio Goshim. Network-guided analysis of hippocampal proteome identifies novel proteins that colocalize with Aβ in a mice model of early-stage Alzheimer's disease. Neurobiology of disease. vol 132. 2020-08-06. PMID:31494281. |
network-guided analysis of hippocampal proteome identifies novel proteins that colocalize with aβ in a mice model of early-stage alzheimer's disease. |
2020-08-06 |
2023-08-13 |
mouse |
| Foteini Christidi, Efstratios Karavasilis, Michail Rentzos, Georgios Velonakis, Vasiliki Zouvelou, Sofia Xirou, Georgios Argyropoulos, Ioannis Papatriantafyllou, Varvara Pantolewn, Panagiotis Ferentinos, Nikolaos Kelekis, Ioannis Seimenis, Ioannis Evdokimidis, Peter Bed. Hippocampal pathology in amyotrophic lateral sclerosis: selective vulnerability of subfields and their associated projections. Neurobiology of aging. vol 84. 2020-08-06. PMID:31629116. |
patients with als and alzheimer's disease have divergent hippocampal signatures. |
2020-08-06 |
2023-08-13 |
Not clear |
| Foteini Christidi, Efstratios Karavasilis, Michail Rentzos, Georgios Velonakis, Vasiliki Zouvelou, Sofia Xirou, Georgios Argyropoulos, Ioannis Papatriantafyllou, Varvara Pantolewn, Panagiotis Ferentinos, Nikolaos Kelekis, Ioannis Seimenis, Ioannis Evdokimidis, Peter Bed. Hippocampal pathology in amyotrophic lateral sclerosis: selective vulnerability of subfields and their associated projections. Neurobiology of aging. vol 84. 2020-08-06. PMID:31629116. |
the cornu ammonis 2/3 subfield and the hippocampus-amygdala transition area are the most affected regions in als in contrast to alzheimer's disease, where the presubiculum and subiculum are the most vulnerable regions. |
2020-08-06 |
2023-08-13 |
Not clear |
| Jessica Z K Caldwell, Jeffrey L Cummings, Sarah J Banks, Sebastian Palmqvist, Oskar Hansso. Cognitively normal women with Alzheimer's disease proteinopathy show relative preservation of memory but not of hippocampal volume. Alzheimer's research & therapy. vol 11. issue 1. 2020-08-06. PMID:31878968. |
cognitively normal women with alzheimer's disease proteinopathy show relative preservation of memory but not of hippocampal volume. |
2020-08-06 |
2023-08-13 |
Not clear |
| Jaewoo Shin, Chanho Kong, Jihyeon Lee, Bo Young Choi, Jiyeon Sim, Chin Su Koh, Minkyung Park, Young Cheol Na, Sang Won Suh, Won Seok Chang, Jin Woo Chan. Focused ultrasound-induced blood-brain barrier opening improves adult hippocampal neurogenesis and cognitive function in a cholinergic degeneration dementia rat model. Alzheimer's research & therapy. vol 11. issue 1. 2020-08-06. PMID:31881998. |
the persistence of adult hippocampal neurogenesis (ahn) is sharply decreased in alzheimer's disease (ad). |
2020-08-06 |
2023-08-13 |
rat |
| Hongming Li, Mohamad Habes, David A Wolk, Yong Fa. A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 15. issue 8. 2020-08-03. PMID:31201098. |
a deep learning model for early prediction of alzheimer's disease dementia based on hippocampal magnetic resonance imaging data. |
2020-08-03 |
2023-08-13 |
Not clear |
| K J Castor, S Shenoi, S P Edminster, T Tran, K S King, H Chui, J M Pogoda, A N Fonteh, M G Harringto. Urine dicarboxylic acids change in pre-symptomatic Alzheimer's disease and reflect loss of energy capacity and hippocampal volume. PloS one. vol 15. issue 4. 2020-08-03. PMID:32298384. |
urine dicarboxylic acids change in pre-symptomatic alzheimer's disease and reflect loss of energy capacity and hippocampal volume. |
2020-08-03 |
2023-08-13 |
human |
| Chia-Hsuan Fu, Daniel Maxim Iascone, Iraklis Petrof, Anupam Hazra, Xiaohong Zhang, Mark S Pyfer, Umberto Tosi, Brian F Corbett, Jingli Cai, Jason Lee, Jin Park, Lorraine Iacovitti, Helen E Scharfman, Grigori Enikolopov, Jeannie Chi. Early Seizure Activity Accelerates Depletion of Hippocampal Neural Stem Cells and Impairs Spatial Discrimination in an Alzheimer's Disease Model. Cell reports. vol 27. issue 13. 2020-07-30. PMID:31242408. |
early seizure activity accelerates depletion of hippocampal neural stem cells and impairs spatial discrimination in an alzheimer's disease model. |
2020-07-30 |
2023-08-13 |
mouse |
| Chia-Hsuan Fu, Daniel Maxim Iascone, Iraklis Petrof, Anupam Hazra, Xiaohong Zhang, Mark S Pyfer, Umberto Tosi, Brian F Corbett, Jingli Cai, Jason Lee, Jin Park, Lorraine Iacovitti, Helen E Scharfman, Grigori Enikolopov, Jeannie Chi. Early Seizure Activity Accelerates Depletion of Hippocampal Neural Stem Cells and Impairs Spatial Discrimination in an Alzheimer's Disease Model. Cell reports. vol 27. issue 13. 2020-07-30. PMID:31242408. |
adult hippocampal neurogenesis has been reported to be decreased, increased, or not changed in alzheimer's disease (ad) patients and related transgenic mouse models. |
2020-07-30 |
2023-08-13 |
mouse |
| Charlotte Gary, Suzanne Lam, Anne-Sophie Hérard, James E Koch, Fanny Petit, Pauline Gipchtein, Stephen J Sawiak, Raphaëlle Caillierez, Sabiha Eddarkaoui, Morvane Colin, Fabienne Aujard, Jean-Philippe Deslys, Emmanuel Brouillet, Luc Buée, Emmanuel E Comoy, Fabien Pifferi, Jean-Luc Picq, Marc Dhenai. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate. Acta neuropathologica communications. vol 7. issue 1. 2020-07-30. PMID:31481130. |
animals inoculated with alzheimer brain homogenates displayed progressive cognitive impairments (clinical tests assessing cognitive and motor functions), modifications of neuronal activity (detected by electroencephalography), widespread and progressive cerebral atrophy (in vivo mri assessing cerebral volume loss using automated voxel-based analysis), neuronal loss in the hippocampus and entorhinal cortex (post mortem stereology). |
2020-07-30 |
2023-08-13 |
mouse |
| A Ahnaou, C Walsh, N V Manyakov, S A Youssef, W H Drinkenbur. Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer's Disease. Neural plasticity. vol 2019. 2020-07-27. PMID:31285742. |
early electrophysiological disintegration of hippocampal neural networks in a novel locus coeruleus tau-seeding mouse model of alzheimer's disease. |
2020-07-27 |
2023-08-13 |
mouse |
| Amal Gregosa, Ángeles Vinuesa, María Florencia Todero, Carlos Pomilio, Soledad P Rossi, Melisa Bentivegna, Jessica Presa, Shirley Wenker, Flavia Saravia, Juan Beauqui. Periodic dietary restriction ameliorates amyloid pathology and cognitive impairment in PDAPP-J20 mice: Potential implication of glial autophagy. Neurobiology of disease. vol 132. 2020-07-27. PMID:31351172. |
our objectives were 1) to evaluate the effects of dietary restriction on cognition, hippocampal amyloid deposition, adult neurogenesis and glial reactivity and autophagy in a mouse model of familial alzheimer's disease, and 2) to analyze the role of glial cells mediating the effects of nutrient restriction in an in vitro model. |
2020-07-27 |
2023-08-13 |
mouse |
| Jing Tian, Lan Guo, Shaomei Sui, Christopher Driskill, Aarron Phensy, Qi Wang, Esha Gauba, Jeffrey M Zigman, Russell H Swerdlow, Sven Kroener, Heng D. Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer's disease. Science translational medicine. vol 11. issue 505. 2020-07-27. PMID:31413143. |
disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor d1 plays a role in alzheimer's disease. |
2020-07-27 |
2023-08-13 |
mouse |
| Jing Tian, Lan Guo, Shaomei Sui, Christopher Driskill, Aarron Phensy, Qi Wang, Esha Gauba, Jeffrey M Zigman, Russell H Swerdlow, Sven Kroener, Heng D. Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer's disease. Science translational medicine. vol 11. issue 505. 2020-07-27. PMID:31413143. |
hippocampal lesions are a defining pathology of alzheimer's disease (ad). |
2020-07-27 |
2023-08-13 |
mouse |
| Victor Bodart-Santos, Luiza R P de Carvalho, Mariana A de Godoy, André F Batista, Leonardo M Saraiva, Luize G Lima, Carla Andreia Abreu, Fernanda G De Felice, Antonio Galina, Rosalia Mendez-Otero, Sergio T Ferreir. Extracellular vesicles derived from human Wharton's jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers. Stem cell research & therapy. vol 10. issue 1. 2020-07-23. PMID:31747944. |
we hypothesized that evs derived from human wharton's jelly would act as mediators of the communication between hmscs and neurons and could protect hippocampal neurons from damage induced by alzheimer's disease-linked amyloid beta oligomers (aβos). |
2020-07-23 |
2023-08-13 |
human |
| Ya-Juan Wang, Yu Wan, Hui-Fu Wang, Chen-Chen Tan, Jie-Qiong Li, Jin-Tai Yu, Lan Ta. Effects of CD33 Variants on Neuroimaging Biomarkers in Non-Demented Elders. Journal of Alzheimer's disease : JAD. vol 68. issue 2. 2020-07-22. PMID:30883353. |
our study examined the effects of the two ad-related cd33 common variants (rs3826656 and rs3865444) on the chosen ad-related brain regions (including hippocampus, amygdala, parahippocampus, middle temporal, entorhinal cortex, and total brain volume) in non-demented elders recruited from the alzheimer's disease neuroimaging initiative database at baseline and during four-year follow-up. |
2020-07-22 |
2023-08-13 |
Not clear |
| Matthew K Tobin, Kianna Musaraca, Ahmed Disouky, Aashutosh Shetti, Abdullah Bheri, William G Honer, Namhee Kim, Robert J Dawe, David A Bennett, Konstantinos Arfanakis, Orly Lazaro. Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients. Cell stem cell. vol 24. issue 6. 2020-07-21. PMID:31130513. |
human hippocampal neurogenesis persists in aged adults and alzheimer's disease patients. |
2020-07-21 |
2023-08-13 |
human |