| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael Evgen'ev, Natalia Bobkova, George Krasnov, David Garbuz, Sergei Funikov, Anna Kudryavtseva, Alexei Kulikov, Alexander Samokhin, Andrey Maltsev, Inna Nesterov. The Effect of Human HSP70 Administration on a Mouse Model of Alzheimer's Disease Strongly Depends on Transgenicity and Age. Journal of Alzheimer's disease : JAD. vol 67. issue 4. 2020-05-27. PMID:30714962. |
herein, we investigated the protective effect of sub-chronic intranasal administration of human hsp70 on the state of neurons in the temporal cortex and areas of the hippocampus of old transgenic (tg) 5xfad mice (11-13 months), representing a late-onset model of hereditary alzheimer's disease. |
2020-05-27 |
2023-08-13 |
mouse |
| Miren Altuna, Amaya Urdánoz-Casado, Javier Sánchez-Ruiz de Gordoa, María V Zelaya, Alberto Labarga, Julie M J Lepesant, Miren Roldán, Idoia Blanco-Luquin, Álvaro Perdones, Rosa Larumbe, Ivonne Jericó, Carmen Echavarri, Iván Méndez-López, Luisa Di Stefano, Maite Mendioro. DNA methylation signature of human hippocampus in Alzheimer's disease is linked to neurogenesis. Clinical epigenetics. vol 11. issue 1. 2020-05-26. PMID:31217032. |
dna methylation signature of human hippocampus in alzheimer's disease is linked to neurogenesis. |
2020-05-26 |
2023-08-13 |
human |
| Soo Jin Park, Jimin Lee, Seunghoon Lee, Sangchul Lim, Juhwan Noh, So Yeon Cho, Junghee Ha, Hyunjeong Kim, Changsoo Kim, Sunho Park, Do Yup Lee, Eosu Ki. Exposure of ultrafine particulate matter causes glutathione redox imbalance in the hippocampus: A neurometabolic susceptibility to Alzheimer's pathology. The Science of the total environment. vol 718. 2020-05-26. PMID:32088476. |
exposure of ultrafine particulate matter causes glutathione redox imbalance in the hippocampus: a neurometabolic susceptibility to alzheimer's pathology. |
2020-05-26 |
2023-08-13 |
mouse |
| Soo Jin Park, Jimin Lee, Seunghoon Lee, Sangchul Lim, Juhwan Noh, So Yeon Cho, Junghee Ha, Hyunjeong Kim, Changsoo Kim, Sunho Park, Do Yup Lee, Eosu Ki. Exposure of ultrafine particulate matter causes glutathione redox imbalance in the hippocampus: A neurometabolic susceptibility to Alzheimer's pathology. The Science of the total environment. vol 718. 2020-05-26. PMID:32088476. |
ufp exposure also induced oxidative stress and neuroinflammation, and importantly, increased alzheimer's beta-amyloid levels in the hippocampus. |
2020-05-26 |
2023-08-13 |
mouse |
| Katarina Ilic, Kristina Mlinac-Jerkovic, Natasa Jovanov-Milosevic, Goran Simic, Nikola Habek, Nenad Bogdanovic, Svjetlana Kalanj-Bogna. Hippocampal expression of cell-adhesion glycoprotein neuroplastin is altered in Alzheimer's disease. Journal of cellular and molecular medicine. vol 23. issue 2. 2020-05-21. PMID:30488668. |
hippocampal expression of cell-adhesion glycoprotein neuroplastin is altered in alzheimer's disease. |
2020-05-21 |
2023-08-13 |
human |
| Katarina Ilic, Kristina Mlinac-Jerkovic, Natasa Jovanov-Milosevic, Goran Simic, Nikola Habek, Nenad Bogdanovic, Svjetlana Kalanj-Bogna. Hippocampal expression of cell-adhesion glycoprotein neuroplastin is altered in Alzheimer's disease. Journal of cellular and molecular medicine. vol 23. issue 2. 2020-05-21. PMID:30488668. |
here, we investigated the hippocampal expression of brain-specific neuroplastin isoform (np65), its relationship with amyloid and tau pathology in alzheimer's disease (ad), and potential involvement of neuroplastin in tissue response during the disease progression. |
2020-05-21 |
2023-08-13 |
human |
| Chongyang Chen, Xin Jiang, Yingchao Li, Haitao Yu, Shupeng Li, Zaijun Zhang, Hua Xu, Ying Yang, Gongping Liu, Feiqi Zhu, Xiaohu Ren, Liangyu Zou, Benhong Xu, Jianjun Liu, Peter S Spencer, Xifei Yan. Low-dose oral copper treatment changes the hippocampal phosphoproteomic profile and perturbs mitochondrial function in a mouse model of Alzheimer's disease. Free radical biology & medicine. vol 135. 2020-05-21. PMID:30862541. |
low-dose oral copper treatment changes the hippocampal phosphoproteomic profile and perturbs mitochondrial function in a mouse model of alzheimer's disease. |
2020-05-21 |
2023-08-13 |
mouse |
| Nicholas C Firth, Silvia Primativo, Razvan-Valentin Marinescu, Timothy J Shakespeare, Aida Suarez-Gonzalez, Manja Lehmann, Amelia Carton, Dilek Ocal, Ivanna Pavisic, Ross W Paterson, Catherine F Slattery, Alexander J M Foulkes, Basil H Ridha, Eulogio Gil-Néciga, Neil P Oxtoby, Alexandra L Young, Marc Modat, M Jorge Cardoso, Sebastien Ourselin, Natalie S Ryan, Bruce L Miller, Gil D Rabinovici, Elizabeth K Warrington, Martin N Rossor, Nick C Fox, Jason D Warren, Daniel C Alexander, Jonathan M Schott, Keir X X Yong, Sebastian J Crutc. Longitudinal neuroanatomical and cognitive progression of posterior cortical atrophy. Brain : a journal of neurology. vol 142. issue 7. 2020-05-18. PMID:31219516. |
patients with typical alzheimer's disease showed early hippocampal atrophy, with subsequent higher rates of temporal atrophy and ventricular expansion. |
2020-05-18 |
2023-08-13 |
human |
| Xuejian Kong, Zhuo Gong, Le Zhang, Xiangdong Sun, Zhenri Ou, Biao Xu, Jingyi Huang, Dahong Long, Xiaosong He, Xiaohong Lin, Qingqing Li, Liping Xu, Aiguo Xua. JAK2/STAT3 signaling mediates IL-6-inhibited neurogenesis of neural stem cells through DNA demethylation/methylation. Brain, behavior, and immunity. vol 79. 2020-05-13. PMID:30763768. |
neuroinflammation, considered as a pathological hallmark of alzheimer's disease (ad), has been demonstrated to affect hippocampal neurogenesis and cognitive function. |
2020-05-13 |
2023-08-13 |
mouse |
| T M Lancaster, M J Hill, R Sims, J William. Microglia - mediated immunity partly contributes to the genetic association between Alzheimer's disease and hippocampal volume. Brain, behavior, and immunity. vol 79. 2020-05-13. PMID:30776473. |
microglia - mediated immunity partly contributes to the genetic association between alzheimer's disease and hippocampal volume. |
2020-05-13 |
2023-08-13 |
Not clear |
| Anna-Lina Gerberding, Silvia Zampar, Martina Stazi, David Liebetanz, Oliver Wirth. Physical Activity Ameliorates Impaired Hippocampal Neurogenesis in the Tg4-42 Mouse Model of Alzheimer's Disease. ASN neuro. vol 11. 2020-05-13. PMID:31818124. |
physical activity ameliorates impaired hippocampal neurogenesis in the tg4-42 mouse model of alzheimer's disease. |
2020-05-13 |
2023-08-13 |
mouse |
| Lan-Xue Zhao, Yan-Hui Ge, Jia-Bing Li, Cai-Hong Xiong, Ping-Yee Law, Jian-Rong Xu, Yu Qiu, Hong-Zhuan Che. M1 muscarinic receptors regulate the phosphorylation of AMPA receptor subunit GluA1 FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 5. 2020-05-12. PMID:30794430. |
m1 muscarinic receptors regulate the phosphorylation of ampa receptor subunit glua1 m1 muscarinic acetylcholine receptors are highly expressed in key areas that control cognition, such as the cortex and hippocampus, representing one potential therapeutic target for cognitive dysfunctions of alzheimer's disease and schizophrenia. |
2020-05-12 |
2023-08-13 |
Not clear |
| Dawson W Hedges, Lance D Erickson, Jackie Kunzelman, Bruce L Brown, Shawn D Gal. Association between exposure to air pollution and hippocampal volume in adults in the UK Biobank. Neurotoxicology. vol 74. 2020-05-12. PMID:31220475. |
several neuropsychiatric diseases including alzheimer's disease are associated with reduced hippocampal volume, and further the hippocampus appears vulnerable to environmental insult. |
2020-05-12 |
2023-08-13 |
Not clear |
| Ryan A Kirk, Raymond P Kesner, Li-Ming Wang, Qi Wu, Rheal A Towner, John M Hoffman, Kathryn A Morto. Lipopolysaccharide exposure in a rat sepsis model results in hippocampal amyloid-β plaque and phosphorylated tau deposition and corresponding behavioral deficits. GeroScience. vol 41. issue 4. 2020-05-12. PMID:31473912. |
hippocampal abnormalities, particularly those of the dentate gyrus, are seen in alzheimer's disease and age-related memory loss. |
2020-05-12 |
2023-08-13 |
rat |
| Seonggyun Han, Jason E Miller, Seyoun Byun, Dokyoon Kim, Shannon L Risacher, Andrew J Saykin, Younghee Lee, Kwangsik Nh. Identification of exon skipping events associated with Alzheimer's disease in the human hippocampus. BMC medical genomics. vol 12. issue Suppl 1. 2020-05-11. PMID:30704480. |
identification of exon skipping events associated with alzheimer's disease in the human hippocampus. |
2020-05-11 |
2023-08-13 |
human |
| Sushma, Amal Chandra Monda. Role of GPCR signaling and calcium dysregulation in Alzheimer's disease. Molecular and cellular neurosciences. vol 101. 2020-05-05. PMID:31655116. |
alzheimer's disease (ad), a late onset neurodegenerative disorder is characterized by the loss of memory, disordered cognitive function, caused by accumulation of amyloid-β (aβ) peptide and neurofibrillary tangles (nfts) in the neocortex and hippocampal brain area. |
2020-05-05 |
2023-08-13 |
Not clear |
| Yi Ying Wang, Meng Gao, Guo Ping Qiu, Jin Xu, Yan Jun Wu, Yi Xu, Jian Rong Wang, Hua Jun Sheng, Shu Juan Zh. [Effect of electroacupuncture on the P35/P25-cyclin-dependent kinase 5-Tau pathway in hippocampus of rats with Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 45. issue 3. 2020-05-04. PMID:32202710. |
[effect of electroacupuncture on the p35/p25-cyclin-dependent kinase 5-tau pathway in hippocampus of rats with alzheimer's disease]. |
2020-05-04 |
2023-08-13 |
rat |
| Yin Fu, Xiaoyang Hu, Chunyu Zheng, Guicai Sun, Jianyu Xu, Shanshan Luo, Peigang Ca. Intrahippocampal miR-342-3p inhibition reduces β-amyloid plaques and ameliorates learning and memory in Alzheimer's disease. Metabolic brain disease. vol 34. issue 5. 2020-04-30. PMID:31134481. |
accumulation of extracellular amyloid-β (aβ) in hippocampal subregions is a hallmark of alzheimer's disease (ad), which promotes neuronal apoptosis, potentiates cognitive decline and play a causative role in ad pathogenesis. |
2020-04-30 |
2023-08-13 |
mouse |
| Kasra Moazzami, Iris Yuefan Shao, Lin Yee Chen, Pamela L Lutsey, Clifford R Jack, Thomas Mosley, David A Joyner, Rebecca Gottesman, Alvaro Alons. Atrial Fibrillation, Brain Volumes, and Subclinical Cerebrovascular Disease (from the Atherosclerosis Risk in Communities Neurocognitive Study [ARIC-NCS]). The American journal of cardiology. vol 125. issue 2. 2020-04-22. PMID:31771759. |
however, af was associated with smaller regional brain volumes (including temporal, occipital, and parietal lobes; deep gray matter; alzheimer disease signature region; and hippocampus [all p <0.05]) after controlling for demographics, cardiovascular risk factors, prevalent cardiovascular disease, and markers of subclinical cerebrovascular disease. |
2020-04-22 |
2023-08-13 |
human |
| Pierre-Yves Jonin, Clara Calia, Sophie Muratot, Serge Belliard, Quentin Duché, Emmanuel J Barbeau, Mario A Parr. Refining understanding of working memory buffers through the construct of binding: Evidence from a single case informs theory and clinical practise. Cortex; a journal devoted to the study of the nervous system and behavior. vol 112. 2020-04-21. PMID:30245198. |
otherwise, and as expected, ka was impaired on three relational memory tasks thought to depend on the hippocampus that are widely used in the early detection of alzheimer's disease. |
2020-04-21 |
2023-08-13 |
Not clear |