All Relations between Alzheimer Disease and magnocellular corticopetal cell complex

Publication Sentence Publish Date Extraction Date Species
Ting Yang, Zhongwei Guo, Jiapeng Li, Hong Zhu, Yulin Cao, Yanping Ding, Xiaozheng Li. Abnormally decreased functional connectivity of the right nucleus basalis of Meynert in Alzheimer's disease patients with depression symptoms. Biological psychology. 2024-03-25. PMID:38527571. abnormally decreased functional connectivity of the right nucleus basalis of meynert in alzheimer's disease patients with depression symptoms. 2024-03-25 2024-03-28 human
Yajun Shi, Dong Cui, Fengzhu Sun, Zhen OuYang, Ruhai Dou, Qing Jiao, Weifang Cao, Guanghui Y. Exploring sexual dimorphism in basal forebrain volume changes during aging and neurodegenerative diseases. iScience. vol 27. issue 3. 2024-02-16. PMID:38361626. in the cross-sectional study, we observed a significant reduction in bf volume in patients with mild cognitive impairment (mci) and alzheimer's disease (ad) compared to healthy controls (hcs), especially in the ch4 subregion. 2024-02-16 2024-02-18 Not clear
Marthe Mieling, Martin Göttlich, Mushfa Yousuf, Nico Bunzec. Basal forebrain activity predicts functional degeneration in the entorhinal cortex in Alzheimer's disease. Brain communications. vol 5. issue 5. 2023-10-30. PMID:37901036. recent models of alzheimer's disease suggest the nucleus basalis of meynert (nbm) as an early origin of structural degeneration followed by the entorhinal cortex (ec). 2023-10-30 2023-11-08 Not clear
Marthe Mieling, Hannah Meier, Nico Bunzec. Structural Degeneration of the Nucleus basalis of Meynert in Mild Cognitive Impairment and Alzheimer's Disease - Evidence from an MRI-based Meta-Analysis. Neuroscience and biobehavioral reviews. 2023-09-17. PMID:37717861. structural degeneration of the nucleus basalis of meynert in mild cognitive impairment and alzheimer's disease - evidence from an mri-based meta-analysis. 2023-09-17 2023-10-07 human
Marthe Mieling, Hannah Meier, Nico Bunzec. Structural Degeneration of the Nucleus basalis of Meynert in Mild Cognitive Impairment and Alzheimer's Disease - Evidence from an MRI-based Meta-Analysis. Neuroscience and biobehavioral reviews. 2023-09-17. PMID:37717861. recent models of alzheimer's disease (ad) suggest that neuropathological changes of the medial temporal lobe, especially entorhinal cortex, are preceded by degenerations of the cholinergic nucleus basalis of meynert (nbm). 2023-09-17 2023-10-07 human
Marthe Mieling, Martin Göttlich, Mushfa Yousuf, Nico Bunzec. Basal forebrain activity predicts functional degeneration in the entorhinal cortex and decreases with Alzheimer's Disease progression. bioRxiv : the preprint server for biology. 2023-04-10. PMID:37034733. recent models of alzheimer's disease (ad) suggest the nucleus basalis of meynert (nbm) as the origin of structural degeneration followed by the entorhinal cortex (ec). 2023-04-10 2023-08-14 Not clear
Julia Schumacher, Nicola J Ray, Calum A Hamilton, Maurizio Bergamino, Paul C Donaghy, Michael Firbank, Rosie Watson, Gemma Roberts, Louise Allan, Nicola Barnett, John T O'Brien, Alan J Thomas, John-Paul Taylo. Free water imaging of the cholinergic system in dementia with Lewy bodies and Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-03-15. PMID:36919460. degeneration of cortical cholinergic projections from the nucleus basalis of meynert (nbm) is characteristic of dementia with lewy bodies (dlb) and alzheimer's disease (ad), whereas involvement of cholinergic projections from the pedunculopontine nucleus (ppn) to the thalamus is less clear. 2023-03-15 2023-08-14 Not clear
Peng Ren, Wencai Ding, Siyang Li, Guiyou Liu, Meng Luo, Wenyang Zhou, Rui Cheng, Yiqun Li, Pingping Wang, Zhipeng Li, Lifen Yao, Qinghua Jiang, Xia Lian. Regional transcriptional vulnerability to basal forebrain functional dysconnectivity in mild cognitive impairment patients. Neurobiology of disease. 2022-12-31. PMID:36586468. nucleus basalis of meynert (nbm), one of the earliest targets of alzheimer's disease (ad), may act as a seed for pathological spreading to its connected regions. 2022-12-31 2023-08-14 human
Yin Jiang, Tian-Shuo Yuan, Ying-Chuan Chen, Peng Guo, Teng-Hong Lian, Yu-Ye Liu, Wei Liu, Yu-Tong Bai, Quan Zhang, Wei Zhang, Jian-Guo Zhan. Deep brain stimulation of the nucleus basalis of Meynert modulates hippocampal-frontoparietal networks in patients with advanced Alzheimer's disease. Translational neurodegeneration. vol 11. issue 1. 2022-12-05. PMID:36471370. deep brain stimulation of the nucleus basalis of meynert modulates hippocampal-frontoparietal networks in patients with advanced alzheimer's disease. 2022-12-05 2023-08-14 Not clear
Yin Jiang, Tian-Shuo Yuan, Ying-Chuan Chen, Peng Guo, Teng-Hong Lian, Yu-Ye Liu, Wei Liu, Yu-Tong Bai, Quan Zhang, Wei Zhang, Jian-Guo Zhan. Deep brain stimulation of the nucleus basalis of Meynert modulates hippocampal-frontoparietal networks in patients with advanced Alzheimer's disease. Translational neurodegeneration. vol 11. issue 1. 2022-12-05. PMID:36471370. deep brain stimulation (dbs) of the nucleus basalis of meynert (nbm) has shown potential for the treatment of mild-to-moderate alzheimer's disease (ad). 2022-12-05 2023-08-14 Not clear
Qingze Zeng, Tiantian Qiu, Kaicheng Li, Xiao Luo, Shuyue Wang, Xiaopei Xu, Xiaocao Liu, Luwei Hong, Jixuan Li, Peiyu Huang, Minming Zhan. Increased functional connectivity between nucleus basalis of Meynert and amygdala in cognitively intact elderly along the Alzheimer's continuum. NeuroImage. Clinical. vol 36. 2022-12-01. PMID:36451361. increased functional connectivity between nucleus basalis of meynert and amygdala in cognitively intact elderly along the alzheimer's continuum. 2022-12-01 2023-08-14 Not clear
Milan Nemy, Martin Dyrba, Frederic Brosseron, Katharina Buerger, Peter Dechent, Laura Dobisch, Michael Ewers, Klaus Fliessbach, Wenzel Glanz, Doreen Goerss, Michael T Heneka, Stefan Hetzer, Enise I Incesoy, Daniel Janowitz, Ingo Kilimann, Christoph Laske, Franziska Maier, Matthias H Munk, Robert Perneczky, Oliver Peters, Lukas Preis, Josef Priller, Boris-Stephan Rauchmann, Sandra Röske, Nina Roy, Klaus Scheffler, Anja Schneider, Björn H Schott, Annika Spottke, Eike J Spruth, Michael Wagner, Jens Wiltfang, Renat Yakupov, Maria Eriksdotter, Erik Westman, Olga Stepankova, Lenka Vyslouzilova, Emrah Düzel, Frank Jessen, Stefan J Teipel, Daniel Ferreir. Cholinergic white matter pathways along the Alzheimer's disease continuum. Brain : a journal of neurology. 2022-10-26. PMID:36288546. previous studies have shown that the cholinergic nucleus basalis of meynert and its white matter projections are affected in alzheimer's disease (ad) dementia and mild cognitive impairment (mci). 2022-10-26 2023-08-14 human
Jolien Schaeverbeke, Sandra O Tomé, Alicja Ronisz, Simona Ospitalieri, Christine A F von Arnim, Markus Otto, Rik Vandenberghe, Dietmar Rudolf Tha. Neuronal loss of the nucleus basalis of Meynert in primary progressive aphasia is associated with Alzheimer's disease neuropathological changes. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022-09-28. PMID:36170544. neuronal loss of the nucleus basalis of meynert in primary progressive aphasia is associated with alzheimer's disease neuropathological changes. 2022-09-28 2023-08-14 Not clear
Manfred J Oswald, Yechao Han, Han Li, Samuel Marashli, Deniz Nouri Oglo, Bhavya Ojha, Paul V Naser, Zheng Gan, Rohini Kune. Cholinergic basal forebrain nucleus of Meynert regulates chronic pain-like behavior via modulation of the prelimbic cortex. Nature communications. vol 13. issue 1. 2022-08-25. PMID:36008394. the basal nucleus of meynert (nbm) subserves critically important functions in attention, arousal and cognition via its profound modulation of neocortical activity and is emerging as a key target in alzheimer's and parkinson's dementias. 2022-08-25 2023-08-14 mouse
Chen-Pei Lin, Irene Frigerio, Baayla D C Boon, Zihan Zhou, Annemieke J M Rozemuller, Femke H Bouwman, Menno M Schoonheim, Wilma D J van de Berg, Laura E Jonkma. Structural (dys)connectivity associates with cholinergic cell density in Alzheimer's disease. Brain : a journal of neurology. 2022-03-08. PMID:35259207. to better understand the pathophysiology of nucleus basalis of meynert atrophy and its neocortical projections in alzheimer's disease, we utilized a combined post-mortem in situ mri and histopathology approach. 2022-03-08 2023-08-13 Not clear
Chen-Pei Lin, Irene Frigerio, Baayla D C Boon, Zihan Zhou, Annemieke J M Rozemuller, Femke H Bouwman, Menno M Schoonheim, Wilma D J van de Berg, Laura E Jonkma. Structural (dys)connectivity associates with cholinergic cell density in Alzheimer's disease. Brain : a journal of neurology. 2022-03-08. PMID:35259207. a total of 19 alzheimer's disease (ten amnestic and nine non-amnestic) and nine non-neurological control donors underwent 3 t t1-weighted mri for anatomical delineation and volume assessment of the nucleus basalis of meynert, and diffusion-weighted imaging for microstructural assessment of the nucleus and its projections. 2022-03-08 2023-08-13 Not clear
Chen-Pei Lin, Irene Frigerio, Baayla D C Boon, Zihan Zhou, Annemieke J M Rozemuller, Femke H Bouwman, Menno M Schoonheim, Wilma D J van de Berg, Laura E Jonkma. Structural (dys)connectivity associates with cholinergic cell density in Alzheimer's disease. Brain : a journal of neurology. 2022-03-08. PMID:35259207. compared to controls, we observed an mri-derived volume reduction and altered microstructural integrity of the nucleus basalis of meynert in alzheimer's disease donors. 2022-03-08 2023-08-13 Not clear
Chen-Pei Lin, Irene Frigerio, Baayla D C Boon, Zihan Zhou, Annemieke J M Rozemuller, Femke H Bouwman, Menno M Schoonheim, Wilma D J van de Berg, Laura E Jonkma. Structural (dys)connectivity associates with cholinergic cell density in Alzheimer's disease. Brain : a journal of neurology. 2022-03-08. PMID:35259207. our study illustrates that in alzheimer's disease, cholinergic degeneration in the nucleus basalis of meynert may contribute to damaged cortical projections, specifically to the temporal lobe, leading to cognitive deterioration. 2022-03-08 2023-08-13 Not clear
Selena Gonzalez, Tyne L M McHugh, Tao Yang, Wassim Syriani, Stephen M Massa, Frank M Longo, Danielle A Simmon. Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage. Neurobiology of disease. vol 162. 2021-12-10. PMID:34838668. degeneration of basal forebrain cholinergic neurons (bfcns) in the nucleus basalis of meynert (nbm) and vertical diagonal band (vdb) along with their connections is a key pathological event leading to memory impairment in alzheimer's disease (ad). 2021-12-10 2023-08-13 mouse
Muhammad Nazmuddin, Ingrid H C H M Philippens, Teus van Laa. Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data. Scientific reports. vol 11. issue 1. 2021-11-29. PMID:34083732. deep brain stimulation (dbs) of the nucleus basalis of meynert (nbm) has been clinically investigated in alzheimer's disease (ad) and lewy body dementia (lbd). 2021-11-29 2023-08-13 human