| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Riekkinen, H Soininen, J Partanen, A Pääkkönen, S Helisalmi, P Riekkine. The ability of THA treatment to increase cortical alpha waves is related to apolipoprotein E genotype of Alzheimer disease patients. Psychopharmacology. vol 129. issue 3. 1997-11-19. PMID:9084068. |
in a previous study, we reported that alzheimer disease (ad) patients with an apolipoprotein e (apoe) epsilon 4 allele (+ apoe4) show more severe loss of nucleus basalis (nb) cholinergic cells than patients without epsilon 4 alleles (-apoe4). |
1997-11-19 |
2023-08-12 |
Not clear |
| S Engelborghs, P P De Dey. The neurochemistry of Alzheimer's disease. Acta neurologica Belgica. vol 97. issue 2. 1997-09-05. PMID:9246374. |
a degeneration of the cholinergic nucleus basalis of meynert characterizes alzheimer's disease and results in neocortical cholinergic deficits correlating with cognitive impairment. |
1997-09-05 |
2023-08-12 |
Not clear |
| E J Mufson, N Lavine, S Jaffar, J H Kordower, R Quirion, H U Saragov. Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease. Experimental neurology. vol 146. issue 1. 1997-08-07. PMID:9225742. |
reduction in p140-trka receptor protein within the nucleus basalis and cortex in alzheimer's disease. |
1997-08-07 |
2023-08-12 |
Not clear |
| S Vyas, F Javoy-Agid, M T Herrero, O Strada, F Boissiere, U Hibner, Y Agi. Expression of Bcl-2 in adult human brain regions with special reference to neurodegenerative disorders. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202314. |
in patients with alzheimer's and parkinson's diseases, quantification of bcl-2 mrna in the nucleus basalis of meynert and substantia nigra, respectively, showed that the expression was unaltered compared with controls, raising the possibility that the expression of other components of apoptosis is modulated. |
1997-07-24 |
2023-08-12 |
mouse |
| K M Cullen, G M Halliday, K L Double, W S Brooks, H Creasey, G A Bro. Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease. Neuroscience. vol 78. issue 3. 1997-07-21. PMID:9153647. |
cell loss in the nucleus basalis is related to regional cortical atrophy in alzheimer's disease. |
1997-07-21 |
2023-08-12 |
human |
| K M Cullen, G M Halliday, K L Double, W S Brooks, H Creasey, G A Bro. Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease. Neuroscience. vol 78. issue 3. 1997-07-21. PMID:9153647. |
cortical atrophy and cell loss in the cholinergic nucleus basalis is a well-established characteristic of alzheimer's disease; however, previous studies not have analysed cholinergic cell loss and cortical atrophy in concert. |
1997-07-21 |
2023-08-12 |
human |
| K M Cullen, G M Halliday, K L Double, W S Brooks, H Creasey, G A Bro. Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease. Neuroscience. vol 78. issue 3. 1997-07-21. PMID:9153647. |
in autopsy brains from eight patients with alzheimer's disease and 12 control subjects, the numbers of nucleus basalis neurons were determined from 50-microm serial nissl-stained sections. |
1997-07-21 |
2023-08-12 |
human |
| K M Cullen, G M Halliday, K L Double, W S Brooks, H Creasey, G A Bro. Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease. Neuroscience. vol 78. issue 3. 1997-07-21. PMID:9153647. |
cell loss in the nucleus basalis was found to range between 89% and 42% in alzheimer's disease compared with controls. |
1997-07-21 |
2023-08-12 |
human |
| K M Cullen, G M Halliday, K L Double, W S Brooks, H Creasey, G A Bro. Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease. Neuroscience. vol 78. issue 3. 1997-07-21. PMID:9153647. |
a highly significant linear relationship was found between cortical volume and nucleus basalis cell number in controls and alzheimer's disease patients, with values for both groups on a single regression line. |
1997-07-21 |
2023-08-12 |
human |
| K M Cullen, G M Halliday, K L Double, W S Brooks, H Creasey, G A Bro. Cell loss in the nucleus basalis is related to regional cortical atrophy in Alzheimer's disease. Neuroscience. vol 78. issue 3. 1997-07-21. PMID:9153647. |
compromised viability of nucleus basalis neurons may precede cortical volume loss as large numbers of neurofibrillary tangles, detected with nickel peroxidase staining, were found in this nucleus in all alzheimer's disease cases, including those with minimal cell loss. |
1997-07-21 |
2023-08-12 |
human |
| J L Mui. Acetylcholine, aging, and Alzheimer's disease. Pharmacology, biochemistry, and behavior. vol 56. issue 4. 1997-07-07. PMID:9130295. |
a substantial body of literature has suggested that the memory and learning deficits associated with alzheimer's disease and aging are attributable to degeneration of the cholinergic magnocellular neurons of the nucleus basalis of meynert (nbm). |
1997-07-07 |
2023-08-12 |
human |
| F Boissiere, B Faucheux, M Ruberg, Y Agid, E C Hirsc. Decreased TrkA gene expression in cholinergic neurons of the striatum and basal forebrain of patients with Alzheimer's disease. Experimental neurology. vol 145. issue 1. 1997-06-27. PMID:9184126. |
the study was performed by in situ hybridization using a 35s-labeled rna probe complementary to human trka mrna on immunohistochemically identified cholinergic neurons of the nucleus basalis of meynert, the ventral striatum, and the putamen in postmortem brains of patients with clinically and neuropathologically confirmed alzheimer's disease and control subjects. |
1997-06-27 |
2023-08-12 |
human |
| F Boissiere, B Faucheux, M Ruberg, Y Agid, E C Hirsc. Decreased TrkA gene expression in cholinergic neurons of the striatum and basal forebrain of patients with Alzheimer's disease. Experimental neurology. vol 145. issue 1. 1997-06-27. PMID:9184126. |
in patients with alzheimer's disease, a decrease in trka mrna expression was observed in the nucleus basalis of meynert (-75%, p < 0.001) and the ventral striatum (-41%, p < 0.01), where the cholinergic neurons degenerate, and also in the anterior (-43%, p < 0.01) and posterior (-51%, p < 0.01) parts of the putamen, where they are spared but display precocious signs of cell alterations. |
1997-06-27 |
2023-08-12 |
human |
| b' M Popovi\\xc4\\x87, K Jovanova-Nesi\\xc4\\x87, N Popovi\\xc4\\x87, N Ugresi\\xc4\\x87, V Kosti\\xc4\\x87, L Raki\\xc4\\x8. Humoral and cell-mediated immune responses following lesions of the nucleus basalis magnocellularis in the rat. The International journal of neuroscience. vol 89. issue 3-4. 1997-05-30. PMID:9134454.' |
the present study was undertaken to elucidate whether electrolytic lesions of nucleus basalis magnocellularis--nbm (an animal model of alzheimer's disease--ad) may influence humoral and cellular immune responses in adult male wistar rats. |
1997-05-30 |
2023-08-12 |
rat |
| D P Behan, O Khongsaly, M J Owens, H D Chung, C B Nemeroff, E B De Souz. Corticotropin-releasing factor (CRF), CRF-binding protein (CRF-BP), and CRF/CRF-BP complex in Alzheimer's disease and control postmortem human brain. Journal of neurochemistry. vol 68. issue 5. 1997-05-15. PMID:9109532. |
complexed hcrf levels were significantly decreased in ba 8/ba 9, ba 22, ba 39, nucleus basalis, and globus pallidus in the alzheimer's group and free hcrf levels were significantly decreased only in three brain areas, ba 4, ba 39, and caudate; substantial (40%) but nonsignificant decreases were also noted in ba 8/ba 9 and ba 22. |
1997-05-15 |
2023-08-12 |
human |
| F Boissière, B Faucheux, Y Agid, E C Hirsc. Expression of catalytic trkB gene in the striatum and the basal forebrain of patients with Alzheimer's disease: an in situ hybridization study. Neuroscience letters. vol 221. issue 2-3. 1997-04-18. PMID:9121684. |
the expression of catalytic trkb gene, encoding for the high affinity brain-derived neurotrophic factor (bdnf) and neurotrophin-4/5 (nt-4/5) receptor, was studied post mortem in the striatum and the nucleus basalis of meynert of patients with alzheimer's disease (ad) and control subjects, using in situ hybridization coupled with choline acetyltransferase immunohistochemistry. |
1997-04-18 |
2023-08-12 |
human |
| A Salehi, J Verhaagen, P A Dijkhuizen, D F Swaa. Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease. Neuroscience. vol 75. issue 2. 1997-03-14. PMID:8931004. |
co-localization of high-affinity neurotrophin receptors in nucleus basalis of meynert neurons and their differential reduction in alzheimer's disease. |
1997-03-14 |
2023-08-12 |
human |
| A Salehi, J Verhaagen, P A Dijkhuizen, D F Swaa. Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease. Neuroscience. vol 75. issue 2. 1997-03-14. PMID:8931004. |
the present study deals with (i) the expression and co-localization of tyrosine kinase receptors (trks) in the human nucleus basalis of meynert and (ii) alterations of these receptors in alzheimer's disease in the nucleus basalis of meynert, an area severely affected in alzheimer's disease. |
1997-03-14 |
2023-08-12 |
human |
| A Salehi, J Verhaagen, P A Dijkhuizen, D F Swaa. Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease. Neuroscience. vol 75. issue 2. 1997-03-14. PMID:8931004. |
the expression of trka, trkb and trkc in the nucleus basalis of meynert of control and alzheimer's disease brains was studied using three polyclonal antibodies specifically recognizing the extracellular domain of trka, trkb and trkc. |
1997-03-14 |
2023-08-12 |
human |
| A Salehi, J Verhaagen, P A Dijkhuizen, D F Swaa. Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease. Neuroscience. vol 75. issue 2. 1997-03-14. PMID:8931004. |
these observations indicate that nucleus basalis of meynert neurons can be supported by more than one neurotrophin and that the degeneration of these neurons in alzheimer's disease is associated with a decreased expression of trk receptors, suggesting a decreased neurotrophin responsiveness of nucleus basalis of meynert neurons in alzheimer's disease. |
1997-03-14 |
2023-08-12 |
human |