| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Strada, E C Hirsch, F Javoy-Agid, S Lehéricy, M Ruberg, J J Hauw, Y Agi. Does loss of nerve growth factor receptors precede loss of cholinergic neurons in Alzheimer's disease? An autoradiographic study in the human striatum and basal forebrain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 12. 1993-01-15. PMID:1464766. |
we have analyzed the state of these receptors by autoradiography, with 125i-ngf as the ligand, in the caudate nucleus, putamen, ventral striatum, nucleus basalis of meynert, and nucleus tegmenti pedunculopontinus of six patients with alzheimer's disease and five controls, matched for age and postmortem delay. |
1993-01-15 |
2023-08-11 |
human |
| O Strada, E C Hirsch, F Javoy-Agid, S Lehéricy, M Ruberg, J J Hauw, Y Agi. Does loss of nerve growth factor receptors precede loss of cholinergic neurons in Alzheimer's disease? An autoradiographic study in the human striatum and basal forebrain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 12. 1993-01-15. PMID:1464766. |
in alzheimer's disease, the density of ngf receptors was markedly decreased in the caudate nucleus, putamen, ventral striatum, and nucleus basalis of meynert. |
1993-01-15 |
2023-08-11 |
human |
| O Strada, E C Hirsch, F Javoy-Agid, S Lehéricy, M Ruberg, J J Hauw, Y Agi. Does loss of nerve growth factor receptors precede loss of cholinergic neurons in Alzheimer's disease? An autoradiographic study in the human striatum and basal forebrain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 12. 1993-01-15. PMID:1464766. |
in contrast, ache staining decreased less in the nucleus basalis of meynert in all alzheimer's disease patients, and in the ventral striatum of those most severely affected. |
1993-01-15 |
2023-08-11 |
human |
| O Strada, S Vyas, E C Hirsch, M Ruberg, A Brice, Y Agid, F Javoy-Agi. Decreased choline acetyltransferase mRNA expression in the nucleus basalis of Meynert in Alzheimer disease: an in situ hybridization study. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 20. 1992-11-17. PMID:1409664. |
decreased choline acetyltransferase mrna expression in the nucleus basalis of meynert in alzheimer disease: an in situ hybridization study. |
1992-11-17 |
2023-08-11 |
human |
| O Strada, S Vyas, E C Hirsch, M Ruberg, A Brice, Y Agid, F Javoy-Agi. Decreased choline acetyltransferase mRNA expression in the nucleus basalis of Meynert in Alzheimer disease: an in situ hybridization study. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 20. 1992-11-17. PMID:1409664. |
the subnormal choline acetyltransferase (choactase) activity in the cerebral cortex of patients with alzheimer disease (ad) is thought to originate from the loss of cholinergic neurons in the nucleus basalis of meynert (nbm). |
1992-11-17 |
2023-08-11 |
human |
| D L Sparks, J C Hunsaker, J T Slevin, S T DeKosky, R J Kryscio, W R Markesber. Monoaminergic and cholinergic synaptic markers in the nucleus basalis of Meynert (nbM): normal age-related changes and the effect of heart disease and Alzheimer's disease. Annals of neurology. vol 31. issue 6. 1992-09-25. PMID:1355334. |
monoaminergic and cholinergic synaptic markers in the nucleus basalis of meynert (nbm): normal age-related changes and the effect of heart disease and alzheimer's disease. |
1992-09-25 |
2023-08-11 |
human |
| D L Sparks, J C Hunsaker, J T Slevin, S T DeKosky, R J Kryscio, W R Markesber. Monoaminergic and cholinergic synaptic markers in the nucleus basalis of Meynert (nbM): normal age-related changes and the effect of heart disease and Alzheimer's disease. Annals of neurology. vol 31. issue 6. 1992-09-25. PMID:1355334. |
neurotransmitter markers for acetylcholine, serotonin (5-ht), and dopamine (da) were measured in autopsied human nucleus basalis of meynert (nbm) from nondemented individuals without heart disease (non-hd) (age range, 4-84 years; n = 77), nondemented individuals with heart disease (hd) (age range, 57-92 years; n = 23), and individuals with alzheimer's disease (ad) (age range, 59-92 years; n = 22). |
1992-09-25 |
2023-08-11 |
human |
| G M Murphy, B D Greenberg, W G Ellis, L S Forno, S M Salamat, P A Gonzalez-DeWhitt, D E Lowery, J R Tinklenberg, L F En. Alzheimer's disease. Beta-amyloid precursor protein expression in the nucleus basalis of Meynert. The American journal of pathology. vol 141. issue 2. 1992-09-10. PMID:1386714. |
the nucleus basalis of meynert (nbm) was examined using immunocytochemistry for beta-amyloid precursor protein (beta app) expression in alzheimer's disease (ad). |
1992-09-10 |
2023-08-11 |
Not clear |
| R S el-Mallakh, D G Kirch, R Shelton, K J Fan, G Pezeshkpour, S Kanhouwa, R J Wyatt, J E Kleinma. The nucleus basalis of Meynert, senile plaques, and intellectual impairment in schizophrenia. The Journal of neuropsychiatry and clinical neurosciences. vol 3. issue 4. 1992-08-18. PMID:1821257. |
the large, hyperchromic, cholinergic neurons of the nucleus basalis of meynert (nbm) and the presence of senile plaques were quantified in postmortem brain tissue from 10 intellectually impaired schizophrenic patients, seven intellectually intact schizophrenic patients, seven control subjects, and three patients with alzheimer's disease. |
1992-08-18 |
2023-08-11 |
human |
| R P Gaykema, C Nyakas, E Horvath, L B Hersh, C Majtenyi, P G Luite. Cholinergic fiber aberrations in nucleus basalis lesioned rat and Alzheimer's disease. Neurobiology of aging. vol 13. issue 3. 1992-08-12. PMID:1625774. |
cholinergic fiber aberrations in nucleus basalis lesioned rat and alzheimer's disease. |
1992-08-12 |
2023-08-11 |
human |
| T Itakura, M Umemoto, I Kamei, H Imai, H Yokote, S Yukawa, N Koma. Autotransplantation of peripheral cholinergic neurons into the brains of Alzheimer model rats. Acta neurochirurgica. vol 115. issue 3-4. 1992-07-15. PMID:1605081. |
eighteen sprague-dawley strain rats were divided into three groups: 1) unoperated control rats, 2) rats that had undergone bilateral destruction of the nucleus basalis of meynert (nbm) (alzheimer model), and 3) the transplantation group in which the vagal nodosal ganglion was transplanted into the cerebral neocortex one week after the bilateral destruction of the meynert nucleus. |
1992-07-15 |
2023-08-11 |
rat |
| I Kracun, H Rosner, V Drnovsek, M Heffer-Lauc, C Cosović, G Lau. Human brain gangliosides in development, aging and disease. The International journal of developmental biology. vol 35. issue 3. 1992-06-25. PMID:1814411. |
in alzheimer's disease, we found all ganglio-series gangliosides (gm1, gd1a, gd1b, gt1b) to be decreased in regions (temporal and frontal cortex and nucleus basalis of meynert) involved in pathogenesis of disease. |
1992-06-25 |
2023-08-11 |
human |
| K Kobayashi, K Miyazu, I Nakamura, Y Fukutani, N Yamaguchi, I Nakanish. Are there sequential morphometrical changes in the nucleus basalis in Alzheimer's disease? European neurology. vol 32. issue 1. 1992-05-19. PMID:1563457. |
are there sequential morphometrical changes in the nucleus basalis in alzheimer's disease? |
1992-05-19 |
2023-08-11 |
human |
| K Kobayashi, K Miyazu, I Nakamura, Y Fukutani, N Yamaguchi, I Nakanish. Are there sequential morphometrical changes in the nucleus basalis in Alzheimer's disease? European neurology. vol 32. issue 1. 1992-05-19. PMID:1563457. |
degenerated neurons of the nucleus basalis of meynert (nbm) were quantitatively analyzed in 3 normal and 3 alzheimer's disease (ad) subjects. |
1992-05-19 |
2023-08-11 |
human |
| K Kobayashi, K Miyazu, Y Fukutani, I Nakamura, N Yamaguch. Morphometric study on the CH4 of the nucleus basalis of Meynert in Alzheimer's disease. Molecular and chemical neuropathology. vol 15. issue 3. 1992-05-18. PMID:1725482. |
morphometric study on the ch4 of the nucleus basalis of meynert in alzheimer's disease. |
1992-05-18 |
2023-08-11 |
Not clear |
| K Kobayashi, K Miyazu, Y Fukutani, I Nakamura, N Yamaguch. Morphometric study on the CH4 of the nucleus basalis of Meynert in Alzheimer's disease. Molecular and chemical neuropathology. vol 15. issue 3. 1992-05-18. PMID:1725482. |
ch4 neurons were studied morphometrically in three normal controls and three patients with alzheimer's disease (ad). |
1992-05-18 |
2023-08-11 |
Not clear |
| A A Farooqui, L J Wallace, L A Horrock. Stimulation of mono- and diacylglycerol lipase activities in ibotenate-induced lesions of nucleus basalis magnocellularis. Neuroscience letters. vol 131. issue 1. 1992-04-02. PMID:1791985. |
ibotenic acid was injected into the nucleus basalis magnocellularis region of rat brain in order to study whether an elevation of lipase activities was associated with the degeneration of cholinergic neurons in this potential animal model of alzheimer's disease. |
1992-04-02 |
2023-08-11 |
rat |
| R U Hasenöhrl, P Gerhardt, J P Husto. Positively reinforcing effects of the neurokinin substance P in the basal forebrain: mediation by its C-terminal sequence. Experimental neurology. vol 115. issue 2. 1992-03-10. PMID:1370940. |
furthermore, neuropathological implications of the present data are considered, since the homologous nucleus basalis of meynert in man is known to degenerate in alzheimer's disease, which is characterized behaviorally by a progressive deterioration in associative functioning. |
1992-03-10 |
2023-08-11 |
rat |
| L J Kromer Vogt, B T Hyman, G W Van Hoesen, A R Damasi. Pathological alterations in the amygdala in Alzheimer's disease. Neuroscience. vol 37. issue 2. 1992-03-10. PMID:2133349. |
this comparison suggests that (1) nuclei receiving and giving rise to hippocampal projections are consistently affected by neuropathological alterations in alzheimer's disease; (2) the nuclei which receive strong cholinergic projections from the nucleus basalis of meynert (e.g. |
1992-03-10 |
2023-08-11 |
Not clear |
| L Bergström, A Garlind, L Nilsson, I Alafuzoff, C J Fowler, B Winblad, R F Cowbur. Regional distribution of somatostatin receptor binding and modulation of adenylyl cyclase activity in Alzheimer's disease brain. Journal of the neurological sciences. vol 105. issue 2. 1992-02-04. PMID:1684616. |
the pattern of change of somatostatin binding in the alzheimer's disease cases observed in the present study differs from the reported pattern of loss of somatostatin neurons and may be secondary to the degeneration of somatostatin receptor-bearing cholinergic afferents arising from the nucleus basalis. |
1992-02-04 |
2023-08-11 |
Not clear |