| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Oyanagi, H Takahashi, K Wakabayashi, F Ikut. Correlative decrease of large neurons in the neostriatum and basal nucleus of Meynert in Alzheimer's disease. Brain research. vol 504. issue 2. 1990-02-06. PMID:2598036. |
a quantitative investigation was performed on the large neurons in the neostriatum and basal nucleus of meynert (bnm) in patients with alzheimer's disease (ad) and progressive supranuclear palsy (psp). |
1990-02-06 |
2023-08-11 |
Not clear |
| W R Gib. Dementia and Parkinson's disease. The British journal of psychiatry : the journal of mental science. vol 154. 1990-02-01. PMID:2557109. |
the associated pathological lesions comprise cortical pathology, either alzheimer's disease or lewy bodies, in combination with moderate degeneration of the subcortical, cholinergic, basal nucleus of meynert. |
1990-02-01 |
2023-08-11 |
Not clear |
| D F Wozniak, G R Stewart, S Finger, J W Olne. Comparison of behavioral effects of nucleus basalis magnocellularis lesions and somatosensory cortex ablation in the rat. Neuroscience. vol 32. issue 3. 1990-02-01. PMID:2689907. |
injecting an excitotoxin into the basal forebrain to destroy nucleus basalis neurons provides a potentially useful animal model for studying the role of these neurons in alzheimer's disease. |
1990-02-01 |
2023-08-11 |
rat |
| D F Wozniak, G R Stewart, S Finger, J W Olne. Comparison of behavioral effects of nucleus basalis magnocellularis lesions and somatosensory cortex ablation in the rat. Neuroscience. vol 32. issue 3. 1990-02-01. PMID:2689907. |
the findings suggest that rats with nucleus basalis lesions manifest disturbances in several of the same spheres (emotionality, somatosensory information processing, memory) that are disrupted in alzheimer's disease and further confirm the utility of the excitotoxin lesion approach for studying the pathophysiology of alzheimer's disease. |
1990-02-01 |
2023-08-11 |
rat |
| K M Schegg, S Nielsen, R M Zweig, J H Peacoc. Decrease in membrane-bound G4 form of acetylcholinesterase in postmortem Alzheimer brain. Progress in clinical and biological research. vol 317. 1990-01-31. PMID:2602428. |
samples of left hippocampus, septal nucleus, parietal lobe (area 40), and nucleus basalis of meynert (nbm) were removed from eight patients with pathologically confirmed alzheimer's disease (ad), four controls, and three patients with non-alzheimer's dementia. |
1990-01-31 |
2023-08-11 |
mouse |
| G A Higgins, E J Mufso. NGF receptor gene expression is decreased in the nucleus basalis in Alzheimer's disease. Experimental neurology. vol 106. issue 3. 1990-01-22. PMID:2556292. |
ngf receptor gene expression is decreased in the nucleus basalis in alzheimer's disease. |
1990-01-22 |
2023-08-11 |
Not clear |
| S J Allen, D Dawbarn, M G Spillantini, M Goedert, G K Wilcock, T H Moss, F M Semenenk. Distribution of beta-nerve growth factor receptors in the human basal forebrain. The Journal of comparative neurology. vol 289. issue 4. 1990-01-22. PMID:2556457. |
in alzheimer's disease there is known to be a reduction in cholinergic function and an apparent loss of neurons in the cholinergic nucleus basalis of meynert. |
1990-01-22 |
2023-08-11 |
human |
| J H Kordower, D M Gash, M Bothwell, L Hersh, E J Mufso. Nerve growth factor receptor and choline acetyltransferase remain colocalized in the nucleus basalis (Ch4) of Alzheimer's patients. Neurobiology of aging. vol 10. issue 1. 1989-08-31. PMID:2547171. |
nerve growth factor receptor and choline acetyltransferase remain colocalized in the nucleus basalis (ch4) of alzheimer's patients. |
1989-08-31 |
2023-08-11 |
Not clear |
| W R Gibb, C Q Mountjoy, D M Mann, A J Lee. A pathological study of the association between Lewy body disease and Alzheimer's disease. Journal of neurology, neurosurgery, and psychiatry. vol 52. issue 6. 1989-08-25. PMID:2545826. |
this suggests that lewy body degeneration in the nucleus basalis of meynert contributes to the deficit of cortical chat, but not to the cortical alzheimer pathology. |
1989-08-25 |
2023-08-11 |
Not clear |
| J L Cumming. Intellectual impairment in Parkinson's disease: clinical, pathologic, and biochemical correlates. Journal of geriatric psychiatry and neurology. vol 1. issue 1. 1989-08-25. PMID:2908099. |
neuropathologic and neurochemical observations demonstrate that pd is a heterogeneous disorder: the classic subcortical pathology with dopamine deficiency may be complicated by atrophy of nucleus basalis and superimposed cortical cholinergic deficits, and a few patients have the histopathologic hallmarks of alzheimer's disease. |
1989-08-25 |
2023-08-11 |
Not clear |
| R P Kesner, T B Adelstein, K A Crutche. Equivalent spatial location memory deficits in rats with medial septum or hippocampal formation lesions and patients with dementia of the Alzheimer's type. Brain and cognition. vol 9. issue 2. 1989-05-11. PMID:2923719. |
college students, healthy elderly subjects, patients diagnosed with mild or moderate dementia of the alzheimer's type, as well as rats with small or large lesions of the medial septum (ms), dorsal hippocampal formation (dhf) or nucleus basalis magnocellularis (nbm) were tested on an item memory task for a five- or six-item list of varying spatial locations. |
1989-05-11 |
2023-08-11 |
human |
| K Kosaka, K Tsuchiya, M Yoshimur. Lewy body disease with and without dementia: a clinicopathological study of 35 cases. Clinical neuropathology. vol 7. issue 6. 1989-03-29. PMID:3224472. |
in some of the cases (25%) with the brainstem type of lbd, the dementia was attributed to an alzheimer pathology, while in many cases (75%), degeneration in the subcortical nuclei, mainly the nucleus basalis of meynert, played a major role in the dementia. |
1989-03-29 |
2023-08-11 |
Not clear |
| V Chan-Pala. Galanin hyperinnervates surviving neurons of the human basal nucleus of Meynert in dementias of Alzheimer's and Parkinson's disease: a hypothesis for the role of galanin in accentuating cholinergic dysfunction in dementia. The Journal of comparative neurology. vol 273. issue 4. 1989-02-21. PMID:2463283. |
galanin hyperinnervates surviving neurons of the human basal nucleus of meynert in dementias of alzheimer's and parkinson's disease: a hypothesis for the role of galanin in accentuating cholinergic dysfunction in dementia. |
1989-02-21 |
2023-08-11 |
human |
| H R Brashear, M S Godec, J Carlse. The distribution of neuritic plaques and acetylcholinesterase staining in the amygdala in Alzheimer's disease. Neurology. vol 38. issue 11. 1988-12-06. PMID:3185903. |
acetylcholinesterase reactivity was reduced in the alzheimer's cases, but the basal nucleus was easily recognized by the characteristic large neurons. |
1988-12-06 |
2023-08-11 |
Not clear |
| S J Allen, D Dawbarn, G K Wilcoc. Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease. Brain research. vol 454. issue 1-2. 1988-10-11. PMID:3409011. |
morphometric immunochemical analysis of neurons in the nucleus basalis of meynert in alzheimer's disease. |
1988-10-11 |
2023-08-11 |
Not clear |
| S J Allen, D Dawbarn, G K Wilcoc. Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease. Brain research. vol 454. issue 1-2. 1988-10-11. PMID:3409011. |
in alzheimer's disease there is a reported loss of large cells in the cholinergic nucleus basalis of meynert. |
1988-10-11 |
2023-08-11 |
Not clear |
| S J Allen, D Dawbarn, G K Wilcoc. Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease. Brain research. vol 454. issue 1-2. 1988-10-11. PMID:3409011. |
it has been suggested, however, that there may be neurons in the nucleus basalis in alzheimer's disease which are atrophied and therefore difficult to distinguish from neuroglia by size. |
1988-10-11 |
2023-08-11 |
Not clear |
| S J Allen, D Dawbarn, G K Wilcoc. Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease. Brain research. vol 454. issue 1-2. 1988-10-11. PMID:3409011. |
it is suggested that in the nucleus basalis in alzheimer's disease, large neurons are not completely lost; many are shrunken and thus excluded from the previous studies of large cells counted in nissl-stained material. |
1988-10-11 |
2023-08-11 |
Not clear |
| G K Wilcock, M M Esiri, D M Bowen, A O Hughe. The differential involvement of subcortical nuclei in senile dementia of Alzheimer's type. Journal of neurology, neurosurgery, and psychiatry. vol 51. issue 6. 1988-09-21. PMID:3404192. |
a subgroup of demented subjects with alzheimer's disease had a relatively preserved basal nucleus, and frontal lobe (cat) choline acetyltransferase activities similar to those in control subjects, but significantly more neuronal loss in the locus caeruleus. |
1988-09-21 |
2023-08-11 |
human |
| G E Gibson, K F Sheu, J P Blass, A Baker, K C Carlson, B Harding, P Perrin. Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease. Archives of neurology. vol 45. issue 8. 1988-08-25. PMID:3395256. |
a report of cell loss in the nucleus basalis of meynert in patients with wernicke-korsakoff disease prompted the examination of thiamine pyrophosphate (tpp)-dependent enzymes in the brain and peripheral tissues of patients with alzheimer's disease. |
1988-08-25 |
2023-08-11 |
Not clear |