| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D L Sparks, W R Markesbery, J T Slevi. Alzheimer's disease: monoamines and spiperone binding reduced in nucleus basalis. Annals of neurology. vol 19. issue 6. 1986-08-13. PMID:2425718. |
levels of dopamine and serotonin, and of their precursors and metabolites, were measured in the nucleus basalis of meynert (nbm) of patients with alzheimer's disease and control patients. |
1986-08-13 |
2023-08-11 |
Not clear |
| P Etienne, Y Robitaille, S Gauthier, N P Nai. Nucleus basalis neuronal loss and neuritic plaques in advanced Alzheimer's disease. Canadian journal of physiology and pharmacology. vol 64. issue 3. 1986-07-14. PMID:3708439. |
nucleus basalis neuronal loss and neuritic plaques in advanced alzheimer's disease. |
1986-07-14 |
2023-08-11 |
Not clear |
| D M Mann, P O Yates, B Marcyniu. A comparison of nerve cell loss in cortical and subcortical structures in Alzheimer's disease. Journal of neurology, neurosurgery, and psychiatry. vol 49. issue 3. 1986-05-22. PMID:3958743. |
loss of nerve cells from temporal cortex, hippocampus, nucleus basalis of meynert and locus caeruleus was measured in 32 patients with alzheimer's disease ranging from 48 to 92 years of age. |
1986-05-22 |
2023-08-11 |
Not clear |
| C Ezrin-Waters, L Resc. The nucleus basalis of Meynert. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 13. issue 1. 1986-04-28. PMID:2937514. |
consistent and severe involvement of the nucleus basalis of meynert has been found in alzheimer's disease and in the dementia accompanying parkinson's disease. |
1986-04-28 |
2023-08-11 |
Not clear |
| S B Dunnett, G Toniolo, A Fine, C N Ryan, A Björklund, S D Iverse. Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis--II. Sensorimotor and learning impairments. Neuroscience. vol 16. issue 4. 1986-03-31. PMID:4094694. |
the cholinergic projection from the nucleus basalis magnocellularis to the neocortex has been implicated in normal memory function and in the dementia of alzheimer's disease. |
1986-03-31 |
2023-08-11 |
rat |
| M F Casanova, L C Walker, P J Whitehouse, D L Pric. Abnormalities of the nucleus basalis in Down's syndrome. Annals of neurology. vol 18. issue 3. 1985-11-13. PMID:2932050. |
since brains of patients with alzheimer's disease show significant loss of neurons in the nucleus basalis of meynert (nbm), we sought to establish normal standards of nbm neurons in persons with down's syndrome and to determine whether reductions in the number of neurons occur with increasing age. |
1985-11-13 |
2023-08-11 |
human |
| V Haroutunian, P Kanof, K L Davi. Pharmacological alleviation of cholinergic lesion induced memory deficits in rats. Life sciences. vol 37. issue 10. 1985-10-09. PMID:4040999. |
the cholinergic cells of the nucleus basalis of meynert (nbm) have recently been found to degenerate in alzheimer's disease and are thought to be at least partly responsible for the cognitive deficits which are characteristic of this disease. |
1985-10-09 |
2023-08-11 |
rat |
| J de Belleroche, I M Gardiner, M H Hamilton, N J Birdsal. Analysis of muscarinic receptor concentration and subtypes following lesion of rat substantia innominata. Brain research. vol 340. issue 2. 1985-10-07. PMID:4027649. |
cholinergic neurones located in the nucleus basalis of meynert (nbm) in the substantia innominata (si) of primates are known to project to cerebral cortex and cell loss in nbm is thought to be associated with the cholinergic deficit seen in alzheimer's disease. |
1985-10-07 |
2023-08-11 |
rat |
| B Dubois, W Mayo, Y Agid, M Le Moal, H Simo. Profound disturbances of spontaneous and learned behaviors following lesions of the nucleus basalis magnocellularis in the rat. Brain research. vol 338. issue 2. 1985-10-01. PMID:4027594. |
it has been shown that a marked decline in the cortical activity of the cholinergic synthesizing enzyme choline-acetyltransferase (chat), accompanied by a severe neuronal loss in the nucleus basalis magnocellularis of meynert occurs in the brains of patients with senile dementia of the alzheimer type. |
1985-10-01 |
2023-08-11 |
rat |
| B Dubois, W Mayo, Y Agid, M Le Moal, H Simo. Profound disturbances of spontaneous and learned behaviors following lesions of the nucleus basalis magnocellularis in the rat. Brain research. vol 338. issue 2. 1985-10-01. PMID:4027594. |
also, it is likely that the lesion of the nucleus basalis magnocellularis in the rat does not exactly reproduce the behavioral syndrome observed in alzheimer's disease in man. |
1985-10-01 |
2023-08-11 |
rat |
| A Fine, S B Dunnett, A Björklund, S D Iverse. Cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 15. 1985-09-06. PMID:3860857. |
the memory dysfunction of alzheimer disease has been associated with a cortical cholinergic deficiency and loss of cholinergic neurons of the nucleus basalis of meynert. |
1985-09-06 |
2023-08-11 |
rat |
| A Fine, S B Dunnett, A Björklund, S D Iverse. Cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 15. 1985-09-06. PMID:3860857. |
this cholinergic component of alzheimer disease can be modeled in the rat by ibotenic acid lesions of the cholinergic nucleus basalis magnocellularis. |
1985-09-06 |
2023-08-11 |
rat |
| C B Saper, D C German, C L Whit. Neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the Alzheimer's type: possible role in cell loss. Neurology. vol 35. issue 8. 1985-09-05. PMID:4022341. |
neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the alzheimer's type: possible role in cell loss. |
1985-09-05 |
2023-08-11 |
Not clear |
| C B Saper, D C German, C L Whit. Neuronal pathology in the nucleus basalis and associated cell groups in senile dementia of the Alzheimer's type: possible role in cell loss. Neurology. vol 35. issue 8. 1985-09-05. PMID:4022341. |
the loss of cortical cholinergic innervation in senile dementia of the alzheimer's type (sdat) is associated with cell loss in the nucleus basalis and related cell groups (magnocellular basal nucleus, mbn). |
1985-09-05 |
2023-08-11 |
Not clear |
| F Koukoli. [Diagnosis of Alzheimer's disease in the aged. II. Quantitative aspects]. Ceskoslovenska patologie. vol 21. issue 2. 1985-08-27. PMID:4017029. |
subclinical forms of alzheimer's disease in old age can be supposed because of the finding of plaques in neocortex and neuronal decrease in nucleus basalis in several cases of the control group. |
1985-08-27 |
2023-08-11 |
Not clear |
| R W Jacobs, N Farivar, L L Butche. Plaque-like lesions in the basal forebrain in Alzheimer's disease. Neuroscience letters. vol 56. issue 3. 1985-08-23. PMID:2410820. |
silver staining (bodian procedure) in the nucleus of the sublenticular substantia innominata (si), also referred to as the nucleus basalis of meynert, was evaluated in autopsy material from patients with alzheimer's disease or senile dementia of the alzheimer type (age at death: mean 69 years, range 63 to 81 years; time between onset of symptoms and death: mean 5.6 years, range 2.5 to 11.0 years). |
1985-08-23 |
2023-08-11 |
Not clear |
| D M Mann, P O Yates, B Marcyniu. Correlation between senile plaque and neurofibrillary tangle counts in cerebral cortex and neuronal counts in cortex and subcortical structures in Alzheimer's disease. Neuroscience letters. vol 56. issue 1. 1985-08-12. PMID:4011048. |
the quantitative relationship between the numbers of senile plaques and neurofibrillary tangles in the temporal cortex and the degree of atrophy and loss of nerve cells from this region and from cortically projecting areas such as the nucleus basalis of meynert, locus coeruleus and raphe nucleus was investigated in 32 patients with alzheimer's disease. |
1985-08-12 |
2023-08-11 |
Not clear |
| P R Stanfield, Y Nakajima, K Yamaguch. Substance P raises neuronal membrane excitability by reducing inward rectification. Nature. vol 315. issue 6019. 1985-07-24. PMID:2582270. |
these neurones have previously been shown to respond to substance p3 and are analogous to the nucleus basalis of meynert in man, which gives a diffuse projection to the cerebral cortex and whose degeneration is the likely cause of alzheimer's disease. |
1985-07-24 |
2023-08-11 |
rat |
| N Butter. Alcoholic Korsakoff's syndrome: some unresolved issues concerning etiology, neuropathology, and cognitive deficits. Journal of clinical and experimental neuropsychology. vol 7. issue 2. 1985-06-20. PMID:3157699. |
furthermore, the report that alcoholic korsakoff patients, like patients with alzheimer's disease, have endured a substantial neuronal loss in the nucleus basalis of meynert has questioned the role of the medial diencephalon in the alcoholic patients' amnesic syndrome. |
1985-06-20 |
2023-08-11 |
Not clear |
| J P Blas. Alzheimer's disease. Disease-a-month : DM. vol 31. issue 4. 1985-06-18. PMID:3886334. |
the classic pathologic changes are alzheimer plaques, neurofibrillary tangles, and loss of subcortical cells, including particularly the cholinergic cells of the nucleus basalis complex. |
1985-06-18 |
2023-08-11 |
Not clear |