| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Klaffke, J Staed. Sundowning and circadian rhythm disorders in dementia. Acta neurologica Belgica. vol 106. issue 4. 2007-04-04. PMID:17323834. |
neuronal degeneration of cholinergic nucleus basalis meynert (nbm) neurons promote rest-activity disturbance and sundowning in alzheimer's disease. |
2007-04-04 |
2023-08-12 |
Not clear |
| Aneta Grudzien, Pamela Shaw, Sandra Weintraub, Eileen Bigio, Deborah C Mash, M Marsel Mesula. Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease. Neurobiology of aging. vol 28. issue 3. 2007-03-01. PMID:16574280. |
neurofibrillary degeneration in the nucleus basalis and a loss of its cortical cholinergic projections are prominent components of the neuropathology in alzheimer's disease (ad). |
2007-03-01 |
2023-08-12 |
human |
| R Huang, S E Podusl. CYP19 haplotypes increase risk for Alzheimer's disease. Journal of medical genetics. vol 43. issue 8. 2006-12-27. PMID:16882736. |
aromatase activity is increased in the nucleus basalis of meynert during aging and in alzheimer's disease (ad), making the gene (cyp19), at 15q21.1, a potential candidate risk factor. |
2006-12-27 |
2023-08-12 |
Not clear |
| Peter J Whitehous. Quality of life: the bridge from the cholinergic basal forebrain to cognitive science and bioethics. Journal of Alzheimer's disease : JAD. vol 9. issue 3 Suppl. 2006-10-19. PMID:16914884. |
our paper on loss of neurons in the nucleus basalis of meynert (now considered part of the cholinergic basal forebrain) in alzheimer disease (ad) stimulated scientific interest in this little studied brain region. |
2006-10-19 |
2023-08-12 |
Not clear |
| Bernhard Rosengarten, Sönke Paulsen, Sandor Molnar, Reiner Kaschel, Bernd Gallhofer, Manfred Kap. Acetylcholine esterase inhibitor donepezil improves dynamic cerebrovascular regulation in Alzheimer patients. Journal of neurology. vol 253. issue 1. 2006-09-29. PMID:16096820. |
alzheimer's disease (ad) leads to a degeneration of the nucleus basalis of meynert and thus to decreased cholinergic tonus in the brain. |
2006-09-29 |
2023-08-12 |
Not clear |
| Mikako Ogawa, Yasuhiko Iida, Masaki Nakagawa, Yugi Kuge, Hidekazu Kawashima, Akiko Tominaga, Masashi Ueda, Yasuhiro Magata, Hideo Saj. Change of central cholinergic receptors following lesions of nucleus basalis magnocellularis in rats: search for an imaging index suitable for the early detection of Alzheimer's disease. Nuclear medicine and biology. vol 33. issue 2. 2006-09-28. PMID:16546680. |
change of central cholinergic receptors following lesions of nucleus basalis magnocellularis in rats: search for an imaging index suitable for the early detection of alzheimer's disease. |
2006-09-28 |
2023-08-12 |
human |
| Mikako Ogawa, Yasuhiko Iida, Masaki Nakagawa, Yugi Kuge, Hidekazu Kawashima, Akiko Tominaga, Masashi Ueda, Yasuhiro Magata, Hideo Saj. Change of central cholinergic receptors following lesions of nucleus basalis magnocellularis in rats: search for an imaging index suitable for the early detection of Alzheimer's disease. Nuclear medicine and biology. vol 33. issue 2. 2006-09-28. PMID:16546680. |
thus, because the dysfunction of cholinergic system that project to the cerebral cortex from nucleus basalis of meynert (nbm) would be implicated in the memory function deficits in alzheimer's disease (ad), evaluating cholinergic function may be useful for the early detection of ad. |
2006-09-28 |
2023-08-12 |
human |
| Scott E Counts, Er-Yun Chen, Shaoli Che, Milos D Ikonomovic, Joanne Wuu, Stephen D Ginsberg, Steven T Dekosky, Elliott J Mufso. Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 21. issue 4. 2006-09-26. PMID:16410678. |
galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of alzheimer's disease. |
2006-09-26 |
2023-08-12 |
human |
| Scott E Counts, Er-Yun Chen, Shaoli Che, Milos D Ikonomovic, Joanne Wuu, Stephen D Ginsberg, Steven T Dekosky, Elliott J Mufso. Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 21. issue 4. 2006-09-26. PMID:16410678. |
galanin (gal)-containing fibers enlarge and hyperinnervate remaining cholinergic basal forebrain (cbf) neurons within the anterior nucleus basalis (nb) in late-stage alzheimer's disease (ad). |
2006-09-26 |
2023-08-12 |
human |
| Stephen D Ginsberg, Shaoli Che, Joanne Wuu, Scott E Counts, Elliott J Mufso. Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease. Journal of neurochemistry. vol 97. issue 2. 2006-06-08. PMID:16539663. |
dysfunction of cholinergic basal forebrain (cbf) neurons of the nucleus basalis (nb) is a cardinal feature of alzheimer's disease (ad) and correlates with cognitive decline. |
2006-06-08 |
2023-08-12 |
Not clear |
| Elisabeth J G Dubelaar, Elliott J Mufson, Wendela G ter Meulen, Joop J Van Heerikhuize, Ronald W H Verwer, Dick F Swaa. Increased metabolic activity in nucleus basalis of Meynert neurons in elderly individuals with mild cognitive impairment as indicated by the size of the Golgi apparatus. Journal of neuropathology and experimental neurology. vol 65. issue 3. 2006-06-05. PMID:16651887. |
in this study, we examined the metabolic activity of nucleus basalis of meynert (nbm) neurons in individuals clinically diagnosed with no cognitive impairment (nci, n = 8), mild cognitive impairment (mci, n = 9), and subjects with moderate alzheimer disease (ad, n = 7). |
2006-06-05 |
2023-08-12 |
human |
| M Villarroya, A G García, J L Marc. New classes of AChE inhibitors with additional pharmacological effects of interest for the treatment of Alzheimer's disease. Current pharmaceutical design. vol 10. issue 25. 2006-04-10. PMID:15544507. |
alzheimer's disease (ad) is associated to a gradual loss of attention and memory that have been associated to impairment of brain cholinergic neurotransmission, particularly a deficit of cholinergic neurons in the nucleus basalis of meynert. |
2006-04-10 |
2023-08-12 |
Not clear |
| Stefan J Teipel, Wilhelm H Flatz, Helmut Heinsen, Arun L W Bokde, Stefan O Schoenberg, Stephanie Stöckel, Olaf Dietrich, Maximilian F Reiser, Hans-Jürgen Möller, Harald Hampe. Measurement of basal forebrain atrophy in Alzheimer's disease using MRI. Brain : a journal of neurology. vol 128. issue Pt 11. 2005-11-28. PMID:16014654. |
alzheimer's disease is characterized by the degeneration and loss of cholinergic neurones in the nucleus basalis meynert, located within the substantia innominata at the ventral surface of the basal forebrain. |
2005-11-28 |
2023-08-12 |
human |
| Stefan J Teipel, Wilhelm H Flatz, Helmut Heinsen, Arun L W Bokde, Stefan O Schoenberg, Stephanie Stöckel, Olaf Dietrich, Maximilian F Reiser, Hans-Jürgen Möller, Harald Hampe. Measurement of basal forebrain atrophy in Alzheimer's disease using MRI. Brain : a journal of neurology. vol 128. issue Pt 11. 2005-11-28. PMID:16014654. |
an in vivo measure of morphological changes in the nucleus basalis meynert would be of high relevance to better understand the structural correlate of cholinergic dysfunction in alzheimer's disease. |
2005-11-28 |
2023-08-12 |
human |
| Stefan J Teipel, Wilhelm H Flatz, Helmut Heinsen, Arun L W Bokde, Stefan O Schoenberg, Stephanie Stöckel, Olaf Dietrich, Maximilian F Reiser, Hans-Jürgen Möller, Harald Hampe. Measurement of basal forebrain atrophy in Alzheimer's disease using MRI. Brain : a journal of neurology. vol 128. issue Pt 11. 2005-11-28. PMID:16014654. |
when matching the locations of signal reductions in the in vivo mri to the template of basal nuclei based on the postmortem brain, signal intensity was decreased in areas corresponding to anterior lateral and anterior medial nucleus basalis meynert and increased in the third ventricle, the transverse fissure and the optic tract in patients with alzheimer's disease compared with controls. |
2005-11-28 |
2023-08-12 |
human |
| Alcyr A Oliveira, Helen M Hodge. Alzheimer's disease and neural transplantation as prospective cell therapy. Current Alzheimer research. vol 2. issue 1. 2005-10-06. PMID:15977991. |
it has long been recognised that alzheimer's disease (ad) patients present an irreversible decline of cognitive functions as consequence of cell deterioration in the forebrain cholinergic projection system (fcps), particularly, in a structure called nucleus basalis of meynert (nbm). |
2005-10-06 |
2023-08-12 |
Not clear |
| A Toledano, M I Alvare. Lesions and dysfunctions of the nucleus basalis as Alzheimer's disease models: general and critical overview and analysis of the long-term changes in several excitotoxic models. Current Alzheimer research. vol 1. issue 3. 2005-09-07. PMID:15975067. |
lesions and dysfunctions of the nucleus basalis as alzheimer's disease models: general and critical overview and analysis of the long-term changes in several excitotoxic models. |
2005-09-07 |
2023-08-12 |
rat |
| Hidekazu Tomimoto, Ryo Ohtani, Masunari Shibata, Noriko Nakamura, Masafumi Ihar. Loss of cholinergic pathways in vascular dementia of the Binswanger type. Dementia and geriatric cognitive disorders. vol 19. issue 5-6. 2005-09-01. PMID:15785029. |
we sought to determine the changes in the cholinergic pathways, which project from the nucleus basalis of meynert (nbm) and travel in the subinsular region, in vascular dementia of the binswanger type (vdbt) and alzheimer's disease (ad). |
2005-09-01 |
2023-08-12 |
Not clear |
| François Sellal, André Nieoullon, Géraldine Michel, Bernard-François Michel, Lucette Lacomblez, Hugo Geerts, Alexandra Delini-Stula, Danièle Bentué-Ferrer, Régis Bordet, Hervé Allai. [Pharmacology of Alzheimer's disease: where do we go from here?]. Therapie. vol 60. issue 2. 2005-07-27. PMID:15969312. |
lesions of the nucleus basalis of meynert, the origin of cholinergic projections to the cortex underlying memory processes); and transgenic models, which are intended to reproduce some of the neuropathological hallmarks of alzheimer's disease. |
2005-07-27 |
2023-08-12 |
Not clear |
| Scott E Counts, Elliott J Mufso. The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease. Journal of neuropathology and experimental neurology. vol 64. issue 4. 2005-05-24. PMID:15835262. |
dysfunction of nerve growth factor (ngf) and its high (trka) and low (p75ntr) affinity receptors has been suggested to underlie the selective degeneration of the nucleus basalis (nb) cholinergic cortical projection neurons in end stage alzheimer disease (ad). |
2005-05-24 |
2023-08-12 |
Not clear |