| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Quirion, I Aubert, Y Robitaille, S Gauthier, D M Araujo, J G Chabo. Neurochemical deficits in pathological brain aging: specificity and possible relevance for treatment strategies. Clinical neuropharmacology. vol 13 Suppl 3. 1991-06-21. PMID:2093419. |
for example, the densities of forebrain cholinergic neurons are markedly decreased in cortical and hippocampal (but not striatal) areas in alzheimer's disease. |
1991-06-21 |
2023-08-11 |
Not clear |
| R Loy, D Heyer, M Clagett-Dame, P S DiStefan. Localization of NGF receptors in normal and Alzheimer's basal forebrain with monoclonal antibodies against the truncated form of the receptor. Journal of neuroscience research. vol 27. issue 4. 1991-04-26. PMID:1964180. |
the distribution of ngfr-containing neurons is similar to that previously described in normal human forebrain, as is the reduction in cell size in nucleus basalis (ch4am) in brains from patients with alzheimer's disease. |
1991-04-26 |
2023-08-11 |
human |
| G A Higgins, G A Oyler, R L Neve, K S Chen, F H Gag. Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 8. 1990-05-24. PMID:1970179. |
morphological and neurochemical changes occur within the forebrain in alzheimer disease and are also correlated with behavioral impairments in aged rats. |
1990-05-24 |
2023-08-11 |
rat |
| J Carlse. New perspectives on the functional anatomical organization of the basolateral amygdala. Acta neurologica Scandinavica. Supplementum. vol 122. 1989-09-18. PMID:2763796. |
the cholinergic system, in particular, has attracted much interest in relation to senile dementia of alzheimer's type (sdat), which often seems to be characterized by disruption of the ventral forebrain cholinergic projection system. |
1989-09-18 |
2023-08-11 |
rat |
| E J Mufson, R Benoit, M M Mesula. Immunohistochemical evidence for a possible somatostatin-containing amygdalostriatal pathway in normal and Alzheimer's disease brain. Brain research. vol 453. issue 1-2. 1988-09-15. PMID:2900053. |
somatostatin (som) immunohistochemistry was used to map som-containing fibers, perikarya and terminal-like structures in the human forebrain of 8 control and 8 alzheimer's diseased patients. |
1988-09-15 |
2023-08-11 |
human |
| A Scicutella, P Davie. Characterization of monoclonal antibodies to galactolipids and uses in studies of dementia. Journal of neuropathology and experimental neurology. vol 47. issue 4. 1988-08-04. PMID:3385437. |
a panel of monoclonal antibodies was prepared from mice immunized with homogenates of ventral forebrain from patients with alzheimer's disease (ad). |
1988-08-04 |
2023-08-11 |
mouse |
| F Hefti, B Wil. Nerve growth factor is a neurotrophic factor for forebrain cholinergic neurons; implications for Alzheimer's disease. Journal of neural transmission. Supplementum. vol 24. 1988-01-19. PMID:2824691. |
nerve growth factor is a neurotrophic factor for forebrain cholinergic neurons; implications for alzheimer's disease. |
1988-01-19 |
2023-08-11 |
human |
| M E Appleyard, A D Smith, P Berman, G K Wilcock, M M Esiri, D Neary, D M Bowe. Cholinesterase activities in cerebrospinal fluid of patients with senile dementia of Alzheimer type. Brain : a journal of neurology. vol 110 ( Pt 5). 1988-01-12. PMID:3676702. |
the lower level of ache in ventricular csf may reflect the changes in this enzyme in forebrain regions of alzheimer patients. |
1988-01-12 |
2023-08-11 |
Not clear |
| L J Thal, P Davie. Detection of antigens in Alzheimer cerebrospinal fluid by monoclonal antibodies. Journal of the American Geriatrics Society. vol 35. issue 12. 1987-12-30. PMID:3680836. |
monoclonal antibodies raised against cerebrospinal fluid (csf) and human ventral forebrain from patients with alzheimer's disease were tested against csf pools derived from patients with alzheimer's disease and normal controls. |
1987-12-30 |
2023-08-11 |
human |
| A Fine, S B Dunnett, A Björklund, S D Iverse. Cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 15. 1985-09-06. PMID:3860857. |
cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of alzheimer disease. |
1985-09-06 |
2023-08-11 |
rat |
| J T Coyle, H Singer, M McKinney, D Pric. Neurotransmitter specific alterations in dementing disorders: insights from animal models. Journal of psychiatric research. vol 18. issue 4. 1985-02-21. PMID:6150995. |
profound reductions in the forebrain cholinergic projections occur in alzheimer's disease. |
1985-02-21 |
2023-08-12 |
human |
| W Chec. Forebrain yields clues to Alzheimer's disease. JAMA. vol 249. issue 15. 1983-05-27. PMID:6403718. |
forebrain yields clues to alzheimer's disease. |
1983-05-27 |
2023-08-12 |
Not clear |
| W J Niklowitz, T I Mandybu. Neurofibrillary changes following childhood lead encephalopathy. Journal of neuropathology and experimental neurology. vol 34. issue 5. 1975-12-23. PMID:1176997. |
numerous pyramidal cells of the forebrain grisea contained alzheimer's neurofibrillary tangles. |
1975-12-23 |
2023-08-11 |
Not clear |