| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nozomi Tomita, Hiroki Katayama, Yuto Kurihara, Toru Takahashi, Sumiya Shibata, Tatsuya Mima, Rieko Osu, Hiroaki Kuman. Tackling social anxiety with targeted brain stimulation: investigating the effects of transcranial static magnetic field stimulation on self-focused attention. Frontiers in behavioral neuroscience. vol 18. 2024-03-28. PMID:38545414. |
previous studies suggested that self-focused attention (sfa), implicated in social anxiety disorder (sad), correlates with heightened activity in the right frontopolar area (rfpa), which is the right prefrontal cortex just behind the forehead. |
2024-03-28 |
2024-03-30 |
Not clear |
| Xin Yang, Fei Gen. Corticotropin-releasing factor signaling and its potential role in the prefrontal cortex-dependent regulation of anxiety. Journal of neuroscience research. 2023-08-18. PMID:37592912. |
then, the role of the crf system in other neuropsychiatric diseases is reviewed and the potential role of pfc crf signaling in the regulation of anxiety disorders is discussed. |
2023-08-18 |
2023-09-07 |
Not clear |
| Xin Yang, Fei Gen. Corticotropin-releasing factor signaling and its potential role in the prefrontal cortex-dependent regulation of anxiety. Journal of neuroscience research. 2023-08-18. PMID:37592912. |
although other signaling pathways are potentially involved in the process of anxiety, crf in the pfc primarily modulates anxiety disorders through the activation of corticotropin-releasing factor type1 receptors (crf-r1) and the excitation of the camp/pka signaling pathway. |
2023-08-18 |
2023-09-07 |
Not clear |
| Huicong Wang, Penghui Song, Yue Hou, Jianghong Liu, Wensi Hao, Shimin Hu, Xiaona Dai, Shuqin Zhan, Ning Li, Mao Peng, Hongxing Wang, Hua Lin, Yuping Wan. 820-nm Transcranial Near-infrared Stimulation on the Left DLPFC Relieved Anxiety: A Randomized, Double-blind, Sham-controlled Study. Brain research bulletin. 2023-06-10. PMID:37301483. |
generalized anxiety disorder (gad) is a chronic mood disease associated with abnormal brain network connections, including decreased activity in the left dorsolateral prefrontal cortex (dlpfc). |
2023-06-10 |
2023-08-14 |
Not clear |
| Nadia N Bouras, Nancy R Mack, Wen-Jun Ga. Prefrontal modulation of anxiety through a lens of noradrenergic signaling. Frontiers in systems neuroscience. vol 17. 2023-05-04. PMID:37139472. |
in contrast, based on current literature review of the individual contributions of ne and the pfc in anxiety disorders, we propose a model of ne level- and adrenergic receptor-dependent, circuit-specific ne-pfc modulation of anxiety disorders. |
2023-05-04 |
2023-08-14 |
Not clear |
| Nadia N Bouras, Nancy R Mack, Wen-Jun Ga. Prefrontal modulation of anxiety through a lens of noradrenergic signaling. Frontiers in systems neuroscience. vol 17. 2023-05-04. PMID:37139472. |
further, the advent of new techniques to measure ne in the pfc with unprecedented spatial and temporal resolution will significantly help us understand how ne modulates pfc function in anxiety disorders. |
2023-05-04 |
2023-08-14 |
Not clear |
| Rodrigo Moraga-Amaro, Paula Muñoz, Tomás Villalobos, Sergio Linsambarth, Francisco Maldonado, Valeria Meirone, Bruno Femopase, Jimmy Stehber. Real-world data of non-invasive stimulation of the human insula-prefrontal cortices using deep TMS to treat anxiety for occupational stress and generalized anxiety disorder. Psychiatry research. vol 320. 2022-12-31. PMID:36586377. |
in this study, the combined stimulation of the insula and pfc using the dtms h4 (insula+lpfc) and h2 (pfc) coils were used to reduce anxiety in 13 subjects experiencing occupational stress, and 55 participants suffering from generalized anxiety disorder (gad). |
2022-12-31 |
2023-08-14 |
human |
| Yihua Chen, Nengyuan Hu, Jianming Yang, Tianming Ga. Prefrontal cortical circuits in anxiety and fear: an overview. Frontiers of medicine. 2022-08-09. PMID:35943704. |
studies have implicated structural changes within the prefrontal cortex (pfc) and functional changes in the communication of the pfc with distal brain structures in anxiety disorders. |
2022-08-09 |
2023-08-14 |
Not clear |
| Yongxiang Li, Shuqing Zhu, Kailai Xie, Xiajie Feng, Lvshuang Chen, Xin Wu, Zhonghua Sun, Gang Shu, Songbo Wang, Canjun Zhu, Ping Gao, Qingyan Jiang, Lina Wan. TLR4 in Tph2 neurons modulates anxiety-related behaviors in a sex-dependent manner. Neuropharmacology. 2022-07-05. PMID:35787402. |
tph2 is a rate-limiting enzyme for 5-ht biosynthesis that is expressed at high levels in the drn, which includes the main 5-ht projection to the hippocampus and prefrontal cortex and regulates anxiety disorder. |
2022-07-05 |
2023-08-14 |
mouse |
| Ceylan Ergül, Çiğdem Ulaşoğlu Yildiz, Elif Kurt, Ani Kiçik, Raşit Tüke. Evaluation of Resting-State Functional Magnetic Resonance Imaging Findings of Patients with Social Anxiety Disorder. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 33. issue 2. 2022-06-22. PMID:35730507. |
the most prominent functional magnetic resonance imaging findings about social anxiety disorder are increased activity in emotional regulation areas (amygdala, insula, hippocampus, dorsal anterior cingulate cortex) and fear circuit, and altered activity in prefrontal cortex. |
2022-06-22 |
2023-08-14 |
Not clear |
| Laith Alexander, Christian M Wood, Angela C Robert. The ventromedial prefrontal cortex and emotion regulation: lost in translation? The Journal of physiology. 2022-05-31. PMID:35635793. |
abstract figure legend the value of non-human primates in bridging the translational divide between correlative functional neuroimaging studies of the ventromedial prefrontal cortex in humans and intervention studies of prelimbic and infralimbic cortex in rodents with a view to understanding the aetiology and treatment of mood and anxiety disorders. |
2022-05-31 |
2023-08-13 |
human |
| Margaux M Kenwood, Ned H Kalin, Helen Barba. Correction: The prefrontal cortex, pathological anxiety, and anxiety disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-02-03. PMID:35110689. |
correction: the prefrontal cortex, pathological anxiety, and anxiety disorders. |
2022-02-03 |
2023-08-13 |
Not clear |
| Adam R Teed, Justin S Feinstein, Maria Puhl, Rachel C Lapidus, Valerie Upshaw, Rayus T Kuplicki, Jerzy Bodurka, Olujimi A Ajijola, Walter H Kaye, Wesley K Thompson, Martin P Paulus, Sahib S Khals. Association of Generalized Anxiety Disorder With Autonomic Hypersensitivity and Blunted Ventromedial Prefrontal Cortex Activity During Peripheral Adrenergic Stimulation: A Randomized Clinical Trial. JAMA psychiatry. 2022-02-02. PMID:35107563. |
association of generalized anxiety disorder with autonomic hypersensitivity and blunted ventromedial prefrontal cortex activity during peripheral adrenergic stimulation: a randomized clinical trial. |
2022-02-02 |
2023-08-13 |
Not clear |
| Nancy R Mack, Suixin Deng, Sha-Sha Yang, Yousheng Shu, Wen-Jun Ga. Prefrontal Cortical Control of Anxiety: Recent Advances. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 2022-01-28. PMID:35086369. |
dysfunction in the prefrontal cortex is commonly implicated in anxiety disorders, but the mechanisms remain unclear. |
2022-01-28 |
2023-08-13 |
Not clear |
| Nancy R Mack, Suixin Deng, Sha-Sha Yang, Yousheng Shu, Wen-Jun Ga. Prefrontal Cortical Control of Anxiety: Recent Advances. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 2022-01-28. PMID:35086369. |
approach-avoidance conflict tasks have been extensively used in animal research to better understand how changes in neural activity within the prefrontal cortex contribute to avoidance behaviors, which are believed to play a major role in the maintenance of anxiety disorders. |
2022-01-28 |
2023-08-13 |
Not clear |
| Margaux M Kenwood, Ned H Kalin, Helen Barba. The prefrontal cortex, pathological anxiety, and anxiety disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 47. issue 1. 2021-12-12. PMID:34400783. |
the prefrontal cortex, pathological anxiety, and anxiety disorders. |
2021-12-12 |
2023-08-13 |
Not clear |
| Margaux M Kenwood, Ned H Kalin, Helen Barba. The prefrontal cortex, pathological anxiety, and anxiety disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 47. issue 1. 2021-12-12. PMID:34400783. |
disruption of specific nodes within the pfc that interface with inhibitory systems can affect the negative bias, failure to regulate autonomic arousal, and avoidance that characterize anxiety disorders. |
2021-12-12 |
2023-08-13 |
Not clear |
| Vahid Nejati, Soheila Khalaji, Hesam Goodarzi, Michael Nitsch. The role of ventromedial and dorsolateral prefrontal cortex in attention and interpretation biases in individuals with general anxiety disorder (GAD): A tDCS study. Journal of psychiatric research. vol 144. 2021-12-07. PMID:34710663. |
the role of ventromedial and dorsolateral prefrontal cortex in attention and interpretation biases in individuals with general anxiety disorder (gad): a tdcs study. |
2021-12-07 |
2023-08-13 |
Not clear |
| Shuang Hu, Xiao-Jun Li, Samuel Law, Chen-Yu Shen, Guan-Qun Yao, Xiao-Qian Zhang, Juan Li, Gui-Fang Chen, Bo Xu, Xiao-Min Liu, Xiang-Yun Ma, Kun Feng, Po-Zi Li. Prefrontal cortex alterations in major depressive disorder, generalized anxiety disorder and their comorbidity during a verbal fluency task assessed by multi-channel near-infrared spectroscopy. Psychiatry research. vol 306. 2021-12-06. PMID:34749225. |
prefrontal cortex alterations in major depressive disorder, generalized anxiety disorder and their comorbidity during a verbal fluency task assessed by multi-channel near-infrared spectroscopy. |
2021-12-06 |
2023-08-13 |
Not clear |
| Rany Abend, Mira A Bajaj, Anita Harrewijn, Chika Matsumoto, Kalina J Michalska, Elizabeth Necka, Esther E Palacios-Barrios, Ellen Leibenluft, Lauren Y Atlas, Daniel S Pin. Threat-anticipatory psychophysiological response is enhanced in youth with anxiety disorders and correlates with prefrontal cortex neuroanatomy. Journal of psychiatry & neuroscience : JPN. vol 46. issue 2. 2021-12-05. PMID:33703868. |
threat-anticipatory psychophysiological response is enhanced in youth with anxiety disorders and correlates with prefrontal cortex neuroanatomy. |
2021-12-05 |
2023-08-13 |
Not clear |